메뉴 건너뛰기




Volumn 42, Issue 11, 2014, Pages 6839-6849

Unraveling the regulatory connections between two controllers of breast cancer cell fate

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; TRANSCRIPTION FACTOR GATA 3;

EID: 84903149344     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku360     Document Type: Article
Times cited : (10)

References (71)
  • 1
    • 79952638264 scopus 로고    scopus 로고
    • Cellular decision making and biological noise: From microbes to mammals
    • Baĺazsi, G., van Oudenaarden, A. and Collins, J.J. (2011) Cellular decision making and biological noise: From microbes to mammals. Cell, 144, 910-925.
    • (2011) Cell , vol.144 , pp. 910-925
    • Baĺazsi, G.1    Van Oudenaarden, A.2    Collins, J.J.3
  • 3
    • 0001389945 scopus 로고
    • Enzyme induction as an all-or-none phenomenon
    • Novick, A. and Weiner, M. (1957) Enzyme induction as an all-or-none phenomenon. Proc. Natl. Acad. Sci. U.S.A., 43, 553-566.
    • (1957) Proc. Natl. Acad. Sci. U.S.A. , vol.43 , pp. 553-566
    • Novick, A.1    Weiner, M.2
  • 5
    • 18744361871 scopus 로고    scopus 로고
    • Enhancement of cellular memory by reducing stochastic transitions
    • Acar, M., Becskei, A. and van Oudenaarden, A. (2005) Enhancement of cellular memory by reducing stochastic transitions. Nature, 435, 228-232.
    • (2005) Nature , vol.435 , pp. 228-232
    • Acar, M.1    Becskei, A.2    Van Oudenaarden, A.3
  • 6
    • 77951604611 scopus 로고    scopus 로고
    • Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression
    • Singh, A., Razooky, B., Cox, C.D., Simpson, M.L. and Weinberger, L.S. (2010) Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression. Biophys. J., 98, L32-L34.
    • (2010) Biophys. J. , vol.98
    • Singh, A.1    Razooky, B.2    Cox, C.D.3    Simpson, M.L.4    Weinberger, L.S.5
  • 8
    • 84878832501 scopus 로고    scopus 로고
    • Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence
    • Narula, J., Williams, C.J., Tiwari, A., Marks-Bluth, J., Pimanda, J.E. and Igoshin, O.A. (2013) Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence. Dev. Biol., 379, 258-269.
    • (2013) Dev. Biol. , vol.379 , pp. 258-269
    • Narula, J.1    Williams, C.J.2    Tiwari, A.3    Marks-Bluth, J.4    Pimanda, J.E.5    Igoshin, O.A.6
  • 9
    • 67349284051 scopus 로고    scopus 로고
    • Non-genetic heterogeneity-A mutation-independent driving force for the somatic evolution of tumours
    • Brock, A., Chang, H. and Huang, S. (2009) Non-genetic heterogeneity-a mutation-independent driving force for the somatic evolution of tumours. Nat. Rev. Genet., 10, 336-342.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 336-342
    • Brock, A.1    Chang, H.2    Huang, S.3
  • 10
    • 84860214990 scopus 로고    scopus 로고
    • Intra-tumour heterogeneity: A looking glass for cancer?
    • Marusyk, A., Almendro, V. and Polyak, K. (2012) Intra-tumour heterogeneity: A looking glass for cancer? Nat. Rev. Cancer, 12, 323-334.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 323-334
    • Marusyk, A.1    Almendro, V.2    Polyak, K.3
  • 14
    • 40349102278 scopus 로고    scopus 로고
    • Estrogen regulation of mammary gland development and breast cancer: Amphiregulin takes center stage
    • LaMarca, H.L. and Rosen, J.M. (2007) Estrogen regulation of mammary gland development and breast cancer: Amphiregulin takes center stage. Breast Cancer Res., 9, 304.
    • (2007) Breast Cancer Res. , vol.9 , pp. 304
    • Lamarca, H.L.1    Rosen, J.M.2
  • 15
    • 0024044464 scopus 로고
    • Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: Findings from National Surgical Adjuvant Breast and Bowel Project Protocol B-06
    • Fisher, B., Redmond, C., Fisher, E.R. and Caplan, R. (1988) Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: Findings from National Surgical Adjuvant Breast and Bowel Project Protocol B-06. J. Clin. Oncol., 6, 1076-1087.
    • (1988) J. Clin. Oncol. , vol.6 , pp. 1076-1087
    • Fisher, B.1    Redmond, C.2    Fisher, E.R.3    Caplan, R.4
  • 16
    • 0028934347 scopus 로고
    • Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer
    • Roodi, N., Bailey, L.R., Kao, W.Y., Verrier, C.S., Yee, C.J., Dupont, W.D. and Parl, F.F. (1995) Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer. J. Natl. Cancer Inst., 87, 446-451.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 446-451
    • Roodi, N.1    Bailey, L.R.2    Kao, W.Y.3    Verrier, C.S.4    Yee, C.J.5    Dupont, W.D.6    Parl, F.F.7
  • 17
    • 0037108359 scopus 로고    scopus 로고
    • Cutting edge: The differential involvement of the N-finger of GATA-3 in chromatin remodeling and transactivation during Th2 development
    • Takemoto, N., Arai, K. and Miyatake, S. (2002) Cutting edge: The differential involvement of the N-finger of GATA-3 in chromatin remodeling and transactivation during Th2 development. J. Immunol., 169, 4103-4107.
    • (2002) J. Immunol. , vol.169 , pp. 4103-4107
    • Takemoto, N.1    Arai, K.2    Miyatake, S.3
  • 18
    • 50449088811 scopus 로고    scopus 로고
    • Minireview: Hormones and mammary cell fate-what will i become when i grow up?
    • LaMarca, H.L. and Rosen, J.M. (2008) Minireview: Hormones and mammary cell fate-what will I become when I grow up? Endocrinology, 149, 4317-4321.
    • (2008) Endocrinology , vol.149 , pp. 4317-4321
    • Lamarca, H.L.1    Rosen, J.M.2
  • 21
    • 0032971250 scopus 로고    scopus 로고
    • GATA-3 is expressed in association with estrogen receptor in breast cancer
    • Hoch, R.V., Thompson, D.A., Baker, R.J. and Weigel, R.J. (1999) GATA-3 is expressed in association with estrogen receptor in breast cancer. Int. J. Cancer, 84, 122-128.
    • (1999) Int. J. Cancer , vol.84 , pp. 122-128
    • Hoch, R.V.1    Thompson, D.A.2    Baker, R.J.3    Weigel, R.J.4
  • 22
    • 29244481995 scopus 로고    scopus 로고
    • Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis
    • Mehra, R., Varambally, S., Ding, L., Shen, R., Sabel, M.S., Ghosh, D., Chinnaiyan, A.M. and Kleer, C.G. (2005) Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis. Cancer Res., 65, 11259-11264.
    • (2005) Cancer Res. , vol.65 , pp. 11259-11264
    • Mehra, R.1    Varambally, S.2    Ding, L.3    Shen, R.4    Sabel, M.S.5    Ghosh, D.6    Chinnaiyan, A.M.7    Kleer, C.G.8
  • 26
    • 77951546955 scopus 로고    scopus 로고
    • GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
    • Yan, W., Cao, Q.J., Arenas, R.B., Bentley, B. and Shao, R. (2010) GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition. J. Biol. Chem., 285, 14042-14051.
    • (2010) J. Biol. Chem. , vol.285 , pp. 14042-14051
    • Yan, W.1    Cao, Q.J.2    Arenas, R.B.3    Bentley, B.4    Shao, R.5
  • 27
    • 84873364088 scopus 로고    scopus 로고
    • GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression
    • Chou, J., Lin, J.H., Brenot, A., Kim, J.W., Provot, S. and Werb, Z. (2013) GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat. Cell Biol., 15, 201-213.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 201-213
    • Chou, J.1    Lin, J.H.2    Brenot, A.3    Kim, J.W.4    Provot, S.5    Werb, Z.6
  • 28
    • 34447130861 scopus 로고    scopus 로고
    • Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer
    • Eeckhoute, J., Keeton, E.K., Lupien, M., Krum, S.A., Carroll, J.S. and Brown, M. (2007) Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Res., 67, 6477-6483.
    • (2007) Cancer Res. , vol.67 , pp. 6477-6483
    • Eeckhoute, J.1    Keeton, E.K.2    Lupien, M.3    Krum, S.A.4    Carroll, J.S.5    Brown, M.6
  • 29
    • 77950667476 scopus 로고    scopus 로고
    • Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop
    • Marconett, C.N., Sundar, S.N., Poindexter, K.M., Stueve, T.R., Bjeldanes, L.F. and Firestone, G.L. (2010) Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop. Mol. Biol. Cell, 21, 1166-1177.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 1166-1177
    • Marconett, C.N.1    Sundar, S.N.2    Poindexter, K.M.3    Stueve, T.R.4    Bjeldanes, L.F.5    Firestone, G.L.6
  • 30
    • 2642544592 scopus 로고    scopus 로고
    • Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
    • Metivier, R., Penot, G., Hubner, M.R., Reid, G., Brand, H., Kos, M. and Gannon, F. (2003) Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell, 115, 751-763.
    • (2003) Cell , vol.115 , pp. 751-763
    • Metivier, R.1    Penot, G.2    Hubner, M.R.3    Reid, G.4    Brand, H.5    Kos, M.6    Gannon, F.7
  • 31
    • 79952901680 scopus 로고    scopus 로고
    • Enhancer function: New insights into the regulation of tissue-specific gene expression
    • Ong, C.T. and Corces, V.G. (2011) Enhancer function: New insights into the regulation of tissue-specific gene expression.Nat. Rev. Genet., 12, 283-293.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 283-293
    • Ong, C.T.1    Corces, V.G.2
  • 34
    • 84867263322 scopus 로고    scopus 로고
    • Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching times
    • Tiwari, A. and Igoshin, O.A. (2012) Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching times. Phys. Biol., 9, 055003.
    • (2012) Phys. Biol. , vol.9 , pp. 055003
    • Tiwari, A.1    Igoshin, O.A.2
  • 35
    • 0035962650 scopus 로고    scopus 로고
    • Chromatin remodeling: Why it is important in cancer
    • Wolffe, A.P. (2001) Chromatin remodeling: Why it is important in cancer. Oncogene, 20, 2988-2990.
    • (2001) Oncogene , vol.20 , pp. 2988-2990
    • Wolffe, A.P.1
  • 36
    • 0035208142 scopus 로고    scopus 로고
    • Minireview: Genomic organization of the human ERalpha gene promoter region
    • Kos, M., Reid, G., Denger, S. and Gannon, F. (2001) Minireview: Genomic organization of the human ERalpha gene promoter region. Mol. Endocrinol., 15, 2057-2063.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 2057-2063
    • Kos, M.1    Reid, G.2    Denger, S.3    Gannon, F.4
  • 38
    • 0036428761 scopus 로고    scopus 로고
    • Negative autoregulation speeds the response times of transcription networks
    • Rosenfeld, N., Elowitz, M.B. and Alon, U. (2002) Negative autoregulation speeds the response times of transcription networks. J. Mol. Biol., 323, 785-793.
    • (2002) J. Mol. Biol. , vol.323 , pp. 785-793
    • Rosenfeld, N.1    Elowitz, M.B.2    Alon, U.3
  • 39
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • Dauvois, S., White, R. and Parker, M.G. (1993) The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J. Cell Sci., 106(Pt 4), 1377-1388.
    • (1993) J. Cell Sci. , vol.106 , Issue.PART 4 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 40
    • 0037351881 scopus 로고    scopus 로고
    • Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling
    • Reid, G., Hubner, M.R., Metivier, R., Brand, H., Denger, S., Manu, D., Beaudouin, J., Ellenberg, J. and Gannon, F. (2003) Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling. Mol. Cell, 11, 695-707.
    • (2003) Mol. Cell , vol.11 , pp. 695-707
    • Reid, G.1    Hubner, M.R.2    Metivier, R.3    Brand, H.4    Denger, S.5    Manu, D.6    Beaudouin, J.7    Ellenberg, J.8    Gannon, F.9
  • 43
    • 41349119880 scopus 로고    scopus 로고
    • Stochastic switching as a survival strategy in fluctuating environments
    • Acar, M., Mettetal, J.T. and van Oudenaarden, A. (2008) Stochastic switching as a survival strategy in fluctuating environments. Nat. Genet., 40, 471-475.
    • (2008) Nat. Genet. , vol.40 , pp. 471-475
    • Acar, M.1    Mettetal, J.T.2    Van Oudenaarden, A.3
  • 45
    • 79954579296 scopus 로고    scopus 로고
    • Bistable responses in bacterial genetic networks: Designs and dynamical consequences
    • Tiwari, A., Ray, J.C., Narula, J. and Igoshin, O.A. (2011) Bistable responses in bacterial genetic networks: Designs and dynamical consequences. Math. Biosci., 231, 76-89.
    • (2011) Math. Biosci. , vol.231 , pp. 76-89
    • Tiwari, A.1    Ray, J.C.2    Narula, J.3    Igoshin, O.A.4
  • 46
    • 53849146767 scopus 로고    scopus 로고
    • Bistability, epigenetics, and bet-hedging in bacteria
    • Veening, J.W., Smits, W.K. and Kuipers, O.P. (2008) Bistability, epigenetics, and bet-hedging in bacteria. Annu. Rev. Microbiol., 62, 193-210.
    • (2008) Annu. Rev. Microbiol. , vol.62 , pp. 193-210
    • Veening, J.W.1    Smits, W.K.2    Kuipers, O.P.3
  • 47
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • Elowitz, M.B., Levine, A.J., Siggia, E.D. and Swain, P.S. (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186.
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3    Swain, P.S.4
  • 48
    • 19544379881 scopus 로고    scopus 로고
    • Stochasticity in gene expression: From theories to phenotypes
    • Kaern, M., Elston, T.C., Blake, W.J. and Collins, J.J. (2005) Stochasticity in gene expression: From theories to phenotypes. Nat. Rev. Genet., 6, 451-464.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 451-464
    • Kaern, M.1    Elston, T.C.2    Blake, W.J.3    Collins, J.J.4
  • 51
    • 0242490781 scopus 로고    scopus 로고
    • Fast evaluation of fluctuations in biochemical networks with the linear noise approximation
    • Elf, J. and Ehrenberg, M. (2003) Fast evaluation of fluctuations in biochemical networks with the linear noise approximation. Genome Res., 13, 2475-2484.
    • (2003) Genome Res. , vol.13 , pp. 2475-2484
    • Elf, J.1    Ehrenberg, M.2
  • 52
    • 0033665572 scopus 로고    scopus 로고
    • Extending the method of mathematically controlled comparison to include numerical comparisons
    • Alves, R. and Savageau, M.A. (2000) Extending the method of mathematically controlled comparison to include numerical comparisons. Bioinformatics, 16, 786-798.
    • (2000) Bioinformatics , vol.16 , pp. 786-798
    • Alves, R.1    Savageau, M.A.2
  • 53
    • 70450228872 scopus 로고    scopus 로고
    • The combination of positive and negative feedback loops confers exquisite flexibility to biochemical switches
    • Pfeuty, B. and Kaneko, K. (2009) The combination of positive and negative feedback loops confers exquisite flexibility to biochemical switches. Phys. Biol., 6, 046013.
    • (2009) Phys. Biol. , vol.6 , pp. 046013
    • Pfeuty, B.1    Kaneko, K.2
  • 54
    • 0036532226 scopus 로고    scopus 로고
    • Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
    • Ferrell, J.E. Jr. (2002) Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability. Curr. Opin. Cell Biol., 14, 140-148.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 140-148
    • Ferrell Jr., J.E.1
  • 56
    • 43149108161 scopus 로고    scopus 로고
    • A bistable Rb-E2F switch underlies the restriction point.Nat
    • Yao, G., Lee, T.J., Mori, S., Nevins, J.R. and You, L. (2008) A bistable Rb-E2F switch underlies the restriction point.Nat. Cell Biol., 10, 476-482.
    • (2008) Cell Biol. , vol.10 , pp. 476-482
    • Yao, G.1    Lee, T.J.2    Mori, S.3    Nevins, J.R.4    You, L.5
  • 57
    • 70350324632 scopus 로고    scopus 로고
    • Emergent bistability by a growth-modulating positive feedback circuit
    • Tan, C., Marguet, P. and You, L. (2009) Emergent bistability by a growth-modulating positive feedback circuit. Nat. Chem. Biol., 5, 842-848.
    • (2009) Nat. Chem. Biol. , vol.5 , pp. 842-848
    • Tan, C.1    Marguet, P.2    You, L.3
  • 59
    • 23844485897 scopus 로고    scopus 로고
    • Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response
    • Laganiere, J., Deblois, G., Lefebvre, C., Bataille, A.R., Robert, F. and Giguere, V. (2005) Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response. Proc. Natl. Acad. Sci. U.S.A., 102, 11651-11656.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 11651-11656
    • Laganiere, J.1    Deblois, G.2    Lefebvre, C.3    Bataille, A.R.4    Robert, F.5    Giguere, V.6
  • 60
    • 33748679908 scopus 로고    scopus 로고
    • A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer
    • Eeckhoute, J., Carroll, J.S., Geistlinger, T.R., Torres-Arzayus, M.I. and Brown, M. (2006) A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes Dev., 20, 2513-2526.
    • (2006) Genes Dev. , vol.20 , pp. 2513-2526
    • Eeckhoute, J.1    Carroll, J.S.2    Geistlinger, T.R.3    Torres-Arzayus, M.I.4    Brown, M.5
  • 61
    • 80052398200 scopus 로고    scopus 로고
    • Cellular reprogramming by the conjoint action of ERalpha, FOXA1, and GATA3 to a ligand-inducible growth state
    • Kong, S.L., Li, G., Loh, S.L., Sung, W.K. and Liu, E.T. (2011) Cellular reprogramming by the conjoint action of ERalpha, FOXA1, and GATA3 to a ligand-inducible growth state. Mol. Syst. Biol., 7, 526.
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 526
    • Kong, S.L.1    Li, G.2    Loh, S.L.3    Sung, W.K.4    Liu, E.T.5
  • 62
    • 33751202983 scopus 로고    scopus 로고
    • GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland
    • Kouros-Mehr, H., Slorach, E.M., Sternlicht, M.D. and Werb, Z. (2006) GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell, 127, 1041-1055.
    • (2006) Cell , vol.127 , pp. 1041-1055
    • Kouros-Mehr, H.1    Slorach, E.M.2    Sternlicht, M.D.3    Werb, Z.4
  • 64
    • 80053611688 scopus 로고    scopus 로고
    • FOXA1: Master of steroid receptor function in cancer
    • Augello, M.A., Hickey, T.E. and Knudsen, K.E. (2011) FOXA1: Master of steroid receptor function in cancer. EMBO J., 30, 3885-3894.
    • (2011) EMBO J. , vol.30 , pp. 3885-3894
    • Augello, M.A.1    Hickey, T.E.2    Knudsen, K.E.3
  • 66
    • 54249137797 scopus 로고    scopus 로고
    • Feedback loops shape cellular signals in space and time
    • Brandman, O. and Meyer, T. (2008) Feedback loops shape cellular signals in space and time. Science, 322, 390-395.
    • (2008) Science , vol.322 , pp. 390-395
    • Brandman, O.1    Meyer, T.2
  • 68
    • 78349256632 scopus 로고    scopus 로고
    • The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response
    • Tiwari, A., Baĺazsi, G., Gennaro, M.L. and Igoshin, O.A. (2010) The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response. Phys. Biol., 7, 036005.
    • (2010) Phys. Biol. , vol.7 , pp. 036005
    • Tiwari, A.1    Baĺazsi, G.2    Gennaro, M.L.3    Igoshin, O.A.4
  • 69
    • 0038048325 scopus 로고    scopus 로고
    • Inferring genetic networks and identifying compound mode of action via expression profiling
    • Gardner, T.S., di Bernardo, D., Lorenz, D. and Collins, J.J. (2003) Inferring genetic networks and identifying compound mode of action via expression profiling. Science, 301, 102-105.
    • (2003) Science , vol.301 , pp. 102-105
    • Gardner, T.S.1    Di Bernardo, D.2    Lorenz, D.3    Collins, J.J.4
  • 70
    • 77249100734 scopus 로고    scopus 로고
    • Network inference and network response identification: Moving genome-scale data to the next level of biological discovery
    • Veiga, D.F., Dutta, B. and Baĺazsi, G. (2010) Network inference and network response identification: Moving genome-scale data to the next level of biological discovery. Mol. Biosyst., 6, 469-480.
    • (2010) Mol. Biosyst. , vol.6 , pp. 469-480
    • Veiga, D.F.1    Dutta, B.2    Baĺazsi, G.3
  • 71
    • 68749118345 scopus 로고    scopus 로고
    • Defining network topologies that can achieve biochemical adaptation
    • Ma, W.Z., Trusina, A., El-Samad, H., Lim, W.A. and Tang, C. (2009) Defining network topologies that can achieve biochemical adaptation. Cell, 138, 760-773.
    • (2009) Cell , vol.138 , pp. 760-773
    • Ma, W.Z.1    Trusina, A.2    El-Samad, H.3    Lim, W.A.4    Tang, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.