메뉴 건너뛰기




Volumn 6, Issue 28, 2015, Pages 24912-24921

Over-expression of ROR2 and Wnt5a cooperatively correlates with unfavorable prognosis in patients with non-small cell lung cancer

Author keywords

immunohistochemistry; Non small cell lung cancer; prognosis; RTK like orphan receptor 2 (ROR2); Wnt5a

Indexed keywords

MESSENGER RNA; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR 2; UNCLASSIFIED DRUG; WNT5A PROTEIN; ONCOPROTEIN; ROR2 PROTEIN, HUMAN; WNT PROTEIN; WNT5A PROTEIN, HUMAN;

EID: 84944460953     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4701     Document Type: Article
Times cited : (54)

References (53)
  • 1
    • 84856662546 scopus 로고    scopus 로고
    • Molecular predictors of prognosis in lung cancer
    • Lin J, Beer DG. Molecular predictors of prognosis in lung cancer. Ann Surg Oncol. 2012; 19:669-676.
    • (2012) Ann Surg Oncol. , vol.19 , pp. 669-676
    • Lin, J.1    Beer, D.G.2
  • 2
    • 84860918028 scopus 로고    scopus 로고
    • Antiangiogenic agents as second-line therapy for advanced non-small cell lung cancer
    • Reckamp KL. Antiangiogenic agents as second-line therapy for advanced non-small cell lung cancer. Cancer Lett. 2012; 321:101-109.
    • (2012) Cancer Lett. , vol.321 , pp. 101-109
    • Reckamp, K.L.1
  • 4
    • 60349084045 scopus 로고    scopus 로고
    • Epidemiology of lung cancer prognosis: quantity and quality of life
    • Yang P. Epidemiology of lung cancer prognosis: quantity and quality of life. Methods Mol Biol. 2009; 471:469-486.
    • (2009) Methods Mol Biol. , vol.471 , pp. 469-486
    • Yang, P.1
  • 5
    • 80052403945 scopus 로고    scopus 로고
    • The EMT regulator slug and lung carcinogenesis
    • Shih JY, Yang PC. The EMT regulator slug and lung carcinogenesis. Carcinogenesis. 2011; 32:1299-1304.
    • (2011) Carcinogenesis. , vol.32 , pp. 1299-1304
    • Shih, J.Y.1    Yang, P.C.2
  • 6
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • Mikels AJ, Nusse R. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol. 2006; 4:e115.
    • (2006) PLoS Biol. , vol.4 , pp. e115
    • Mikels, A.J.1    Nusse, R.2
  • 7
    • 0036159121 scopus 로고    scopus 로고
    • The Ror receptor tyrosine kinase family
    • Forrester WC. The Ror receptor tyrosine kinase family. Cell Mol Life Sci. 2002; 59:83-96.
    • (2002) Cell Mol Life Sci. , vol.59 , pp. 83-96
    • Forrester, W.C.1
  • 12
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S, Moon RT. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol. 2009; 10:468-477.
    • (2009) Nat Rev Mol Cell Biol. , vol.10 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 14
    • 84864352822 scopus 로고    scopus 로고
    • Wnt5a can both activate and repress Wnt/beta-catenin signaling during mouse embryonic development
    • Van Amerongen R, Fuerer C, Mizutani M, Nusse R. Wnt5a can both activate and repress Wnt/beta-catenin signaling during mouse embryonic development. Dev Biol. 2012; 369:101-114.
    • (2012) Dev Biol. , vol.369 , pp. 101-114
    • Van Amerongen, R.1    Fuerer, C.2    Mizutani, M.3    Nusse, R.4
  • 16
    • 39749108763 scopus 로고    scopus 로고
    • The complex pathways of Wnt 5a in cancer progression
    • Pukrop T, Binder C. The complex pathways of Wnt 5a in cancer progression. J Mol Med (Berl). 2008; 86:259-266.
    • (2008) J Mol Med (Berl). , vol.86 , pp. 259-266
    • Pukrop, T.1    Binder, C.2
  • 17
    • 84886109721 scopus 로고    scopus 로고
    • Upregulation of Wnt5a promotes epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells
    • Bo H, Zhang S, Gao L, Chen Y, Zhang J, Chang X, Zhu M. Upregulation of Wnt5a promotes epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells. BMC Cancer. 2013; 13:496.
    • (2013) BMC Cancer. , vol.13 , pp. 496
    • Bo, H.1    Zhang, S.2    Gao, L.3    Chen, Y.4    Zhang, J.5    Chang, X.6    Zhu, M.7
  • 19
    • 84876457158 scopus 로고    scopus 로고
    • WNT5A is a key regulator of the epithelial-mesenchymal transition and cancer stem cell properties in human gastric carcinoma cells
    • Kanzawa M, Semba S, Hara S, Itoh T, Yokozaki H. WNT5A is a key regulator of the epithelial-mesenchymal transition and cancer stem cell properties in human gastric carcinoma cells. Pathobiology. 2013; 80:235-244.
    • (2013) Pathobiology. , vol.80 , pp. 235-244
    • Kanzawa, M.1    Semba, S.2    Hara, S.3    Itoh, T.4    Yokozaki, H.5
  • 20
    • 27144450534 scopus 로고    scopus 로고
    • Wnt-5a protein expression in primary dukes B colon cancers identifies a subgroup of patients with good prognosis
    • Dejmek J, Dejmek A, Safholm A, Sjolander A, Andersson T. Wnt-5a protein expression in primary dukes B colon cancers identifies a subgroup of patients with good prognosis. Cancer Res. 2005; 65:9142-9146.
    • (2005) Cancer Res. , vol.65 , pp. 9142-9146
    • Dejmek, J.1    Dejmek, A.2    Safholm, A.3    Sjolander, A.4    Andersson, T.5
  • 22
    • 84903622908 scopus 로고    scopus 로고
    • Wnt5a suppresses colon cancer by inhibiting cell proliferation and epithelial-mesenchymal transition
    • Cheng R, Sun B, Liu Z, Zhao X, Qi L, Li Y, Gu Q. Wnt5a suppresses colon cancer by inhibiting cell proliferation and epithelial-mesenchymal transition. J Cell Physiol. 2014; 229:1908-1917.
    • (2014) J Cell Physiol. , vol.229 , pp. 1908-1917
    • Cheng, R.1    Sun, B.2    Liu, Z.3    Zhao, X.4    Qi, L.5    Li, Y.6    Gu, Q.7
  • 31
    • 52149117142 scopus 로고    scopus 로고
    • Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling
    • Winkel A, Stricker S, Tylzanowski P, Seiffart V, Mundlos S, Gross G, Hoffmann A. Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling. Cellular signalling. 2008; 20:2134-2144.
    • (2008) Cellular signalling. , vol.20 , pp. 2134-2144
    • Winkel, A.1    Stricker, S.2    Tylzanowski, P.3    Seiffart, V.4    Mundlos, S.5    Gross, G.6    Hoffmann, A.7
  • 32
    • 84869065974 scopus 로고    scopus 로고
    • ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy
    • Rebagay G, Yan S, Liu C, Cheung NK. ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy. Frontiers in oncology. 2012; 2:34.
    • (2012) Frontiers in oncology. , vol.2 , pp. 34
    • Rebagay, G.1    Yan, S.2    Liu, C.3    Cheung, N.K.4
  • 34
    • 84879205263 scopus 로고    scopus 로고
    • Prognostic significance of Ror2 and Wnt5a expression in medulloblastoma
    • Lee SE, Lim SD, Kang SY, Suh SB, Suh YL. Prognostic significance of Ror2 and Wnt5a expression in medulloblastoma. Brain pathology. 2013; 23:445-453.
    • (2013) Brain pathology. , vol.23 , pp. 445-453
    • Lee, S.E.1    Lim, S.D.2    Kang, S.Y.3    Suh, S.B.4    Suh, Y.L.5
  • 40
    • 33646800545 scopus 로고    scopus 로고
    • Wnt signal pathways and neural stem cell differentiation
    • Lange C, Mix E, Rateitschak K, Rolfs A. Wnt signal pathways and neural stem cell differentiation. Neurodegener Dis. 2006; 3:76-86.
    • (2006) Neurodegener Dis. , vol.3 , pp. 76-86
    • Lange, C.1    Mix, E.2    Rateitschak, K.3    Rolfs, A.4
  • 41
    • 0028589430 scopus 로고
    • Induction of kidney epithelial morphogenesis by cells expressing Wnt-1
    • Herzlinger D, Qiao J, Cohen D, Ramakrishna N, Brown AM. Induction of kidney epithelial morphogenesis by cells expressing Wnt-1. Dev Biol. 1994; 166:815-818.
    • (1994) Dev Biol. , vol.166 , pp. 815-818
    • Herzlinger, D.1    Qiao, J.2    Cohen, D.3    Ramakrishna, N.4    Brown, A.M.5
  • 42
    • 0032518695 scopus 로고    scopus 로고
    • Signal transduction by the Wnt family of ligands
    • Dale TC. Signal transduction by the Wnt family of ligands. Biochem J. 1998; 329:209-223.
    • (1998) Biochem J. , vol.329 , pp. 209-223
    • Dale, T.C.1
  • 44
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature. 2005; 434:843-850.
    • (2005) Nature. , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 45
    • 84899496157 scopus 로고    scopus 로고
    • Wnt5a involved in regulation of the biological behavior of hepatocellular carcinoma
    • Bi L, Liu X, Wang C, Cao Y, Mao R, Li P, Geng M. Wnt5a involved in regulation of the biological behavior of hepatocellular carcinoma. Int J Clin Exp Pathol. 2014; 7:987-995.
    • (2014) Int J Clin Exp Pathol. , vol.7 , pp. 987-995
    • Bi, L.1    Liu, X.2    Wang, C.3    Cao, Y.4    Mao, R.5    Li, P.6    Geng, M.7
  • 46
    • 0028902359 scopus 로고
    • Wnt5a cloning, expression, and up-regulation in human primary breast cancers
    • Lejeune S, Huguet EL, Hamby A, Poulsom R, Harris AL. Wnt5a cloning, expression, and up-regulation in human primary breast cancers. Clin Cancer Res. 1995; 1:215-222.
    • (1995) Clin Cancer Res. , vol.1 , pp. 215-222
    • Lejeune, S.1    Huguet, E.L.2    Hamby, A.3    Poulsom, R.4    Harris, A.L.5
  • 47
    • 67650594771 scopus 로고    scopus 로고
    • The opposing roles of Wnt-5a in cancer
    • McDonald SL, Silver A. The opposing roles of Wnt-5a in cancer. Br J Cancer. 2009; 101:209-214.
    • (2009) Br J Cancer. , vol.101 , pp. 209-214
    • McDonald, S.L.1    Silver, A.2
  • 48
    • 33644833865 scopus 로고    scopus 로고
    • Wnt5a expression is associated with the tumor proliferation and the stromal vascular endothelial growth factor-an expression in non-small-cell lung cancer
    • Huang CL, Liu D, Nakano J, Ishikawa S, Kontani K, Yokomise H, Ueno M. Wnt5a expression is associated with the tumor proliferation and the stromal vascular endothelial growth factor-an expression in non-small-cell lung cancer. J Clin Oncol. 2005; 23:8765-8773.
    • (2005) J Clin Oncol. , vol.23 , pp. 8765-8773
    • Huang, C.L.1    Liu, D.2    Nakano, J.3    Ishikawa, S.4    Kontani, K.5    Yokomise, H.6    Ueno, M.7
  • 49
    • 34247589181 scopus 로고    scopus 로고
    • Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway
    • Schambony A, Wedlich D. Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway. Dev Cell. 2007; 12:779-792.
    • (2007) Dev Cell. , vol.12 , pp. 779-792
    • Schambony, A.1    Wedlich, D.2
  • 50
    • 34547103285 scopus 로고    scopus 로고
    • Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells
    • MacLeod RJ, Hayes M, Pacheco I. Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells. Am J Physiol Gastrointest Liver Physiol. 2007; 293:G403-411.
    • (2007) Am J Physiol Gastrointest Liver Physiol. , vol.293 , pp. G403-411
    • MacLeod, R.J.1    Hayes, M.2    Pacheco, I.3
  • 52
    • 67849110291 scopus 로고    scopus 로고
    • The 7th Edition of TNM in Lung Cancer: what now?
    • Goldstraw P. The 7th Edition of TNM in Lung Cancer: what now? J Thorac Oncol. 2009; 4:671-673.
    • (2009) J Thorac Oncol. , vol.4 , pp. 671-673
    • Goldstraw, P.1
  • 53
    • 84919925517 scopus 로고    scopus 로고
    • Prognostic value of LAMP3 and TP53 overexpression in benign and malignant gastrointestinal tissues
    • Sun R, Wang X, Zhu H, Mei H, Wang W, Zhang S, Huang J. Prognostic value of LAMP3 and TP53 overexpression in benign and malignant gastrointestinal tissues. Oncotarget. 2014; 5:12398-12409.
    • (2014) Oncotarget. , vol.5 , pp. 12398-12409
    • Sun, R.1    Wang, X.2    Zhu, H.3    Mei, H.4    Wang, W.5    Zhang, S.6    Huang, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.