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Volumn 23, Issue 4, 2013, Pages 445-453

Prognostic significance of Ror2 and Wnt5a expression in medulloblastoma

Author keywords

medulloblastoma; prognostic factor; Ror2; Wnt 5a; WNT pathway

Indexed keywords

BETA CATENIN; MESSENGER RNA; ROR2 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT5A PROTEIN;

EID: 84879205263     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12017     Document Type: Article
Times cited : (23)

References (31)
  • 2
    • 84862808809 scopus 로고    scopus 로고
    • ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour
    • Edris B, Espinosa I, Muhlenberg T, Mikels A, Lee CH, Steigen SE, et al (2012) ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour. J Pathol 227: 223-233.
    • (2012) J Pathol , vol.227 , pp. 223-233
    • Edris, B.1    Espinosa, I.2    Muhlenberg, T.3    Mikels, A.4    Lee, C.H.5    Steigen, S.E.6
  • 3
    • 77956227746 scopus 로고    scopus 로고
    • Childhood medulloblastoma: Novel approaches to the classification of a heterogeneous disease
    • Ellison DW, (2010) Childhood medulloblastoma: novel approaches to the classification of a heterogeneous disease. Acta Neuropathol 120: 305-316.
    • (2010) Acta Neuropathol , vol.120 , pp. 305-316
    • Ellison, D.W.1
  • 4
    • 65849356587 scopus 로고    scopus 로고
    • Beta-catenin status in paediatric medulloblastomas: Correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics
    • Fattet S, Haberler C, Legoix P, Varlet P, Lellouch-Tubiana A, Lair S, et al (2009) Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics. J Pathol 218: 86-94.
    • (2009) J Pathol , vol.218 , pp. 86-94
    • Fattet, S.1    Haberler, C.2    Legoix, P.3    Varlet, P.4    Lellouch-Tubiana, A.5    Lair, S.6
  • 5
    • 0036159121 scopus 로고    scopus 로고
    • The Ror receptor tyrosine kinase family
    • Forrester WC, (2002) The Ror receptor tyrosine kinase family. Cell Mol Life Sci 59: 83-96.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 83-96
    • Forrester, W.C.1
  • 6
    • 84859061223 scopus 로고    scopus 로고
    • Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis
    • Geng M, Cao YC, Chen YJ, Jiang H, Bi LQ, Liu XH, (2012) Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis. World J Gastroenterol 18: 1328-1338.
    • (2012) World J Gastroenterol , vol.18 , pp. 1328-1338
    • Geng, M.1    Cao, Y.C.2    Chen, Y.J.3    Jiang, H.4    Bi, L.Q.5    Liu, X.H.6
  • 9
    • 33644698339 scopus 로고    scopus 로고
    • WNT/PCP signaling pathway and human cancer (review)
    • Katoh M, (2005) WNT/PCP signaling pathway and human cancer (review). Oncol Rep 14: 1583-1588.
    • (2005) Oncol Rep , vol.14 , pp. 1583-1588
    • Katoh, M.1
  • 11
    • 77952671657 scopus 로고    scopus 로고
    • The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma
    • Kongkham PN, Northcott PA, Croul SE, Smith CA, Taylor MD, Rutka JT, (2010) The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma. Oncogene 29: 3017-3024.
    • (2010) Oncogene , vol.29 , pp. 3017-3024
    • Kongkham, P.N.1    Northcott, P.A.2    Croul, S.E.3    Smith, C.A.4    Taylor, M.D.5    Rutka, J.T.6
  • 12
    • 84863393028 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
    • Kool M, Korshunov A, Remke M, Jones DT, Schlanstein M, Northcott PA, et al (2012) Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol 123: 473-484.
    • (2012) Acta Neuropathol , vol.123 , pp. 473-484
    • Kool, M.1    Korshunov, A.2    Remke, M.3    Jones, D.T.4    Schlanstein, M.5    Northcott, P.A.6
  • 14
    • 39849091185 scopus 로고    scopus 로고
    • Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2
    • Li C, Chen H, Hu L, Xing Y, Sasaki T, Villosis MF, et al (2008) Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2. BMC Mol Biol 9: 11.
    • (2008) BMC Mol Biol , vol.9 , pp. 11
    • Li, C.1    Chen, H.2    Hu, L.3    Xing, Y.4    Sasaki, T.5    Villosis, M.F.6
  • 15
    • 79958171015 scopus 로고    scopus 로고
    • Wnt/beta-catenin pathway in human glioma: Expression pattern and clinical/prognostic correlations
    • Liu C, Tu Y, Sun X, Jiang J, Jin X, Bo X, et al (2011) Wnt/beta-catenin pathway in human glioma: expression pattern and clinical/prognostic correlations. Clin Exp Med 11: 105-112.
    • (2011) Clin Exp Med , vol.11 , pp. 105-112
    • Liu, C.1    Tu, Y.2    Sun, X.3    Jiang, J.4    Jin, X.5    Bo, X.6
  • 16
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan CY, Nusse R, (2004) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20: 781-810.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 18
    • 0027074850 scopus 로고
    • A novel family of cell surface receptors with tyrosine kinase-like domain
    • Masiakowski P, Carroll RD, (1992) A novel family of cell surface receptors with tyrosine kinase-like domain. J Biol Chem 267: 26181-26190.
    • (1992) J Biol Chem , vol.267 , pp. 26181-26190
    • Masiakowski, P.1    Carroll, R.D.2
  • 19
    • 67650594771 scopus 로고    scopus 로고
    • The opposing roles of Wnt-5a in cancer
    • McDonald SL, Silver A, (2009) The opposing roles of Wnt-5a in cancer. Br J Cancer 101: 209-214.
    • (2009) Br J Cancer , vol.101 , pp. 209-214
    • McDonald, S.L.1    Silver, A.2
  • 20
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • Mikels AJ, Nusse R, (2006) Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. Plos Biol 4: e115.
    • (2006) Plos Biol , vol.4
    • Mikels, A.J.1    Nusse, R.2
  • 21
    • 0035964486 scopus 로고    scopus 로고
    • Trk receptor tyrosine kinases: A bridge between cancer and neural development
    • Nakagawara A, (2001) Trk receptor tyrosine kinases: a bridge between cancer and neural development. Cancer Lett 169: 107-114.
    • (2001) Cancer Lett , vol.169 , pp. 107-114
    • Nakagawara, A.1
  • 22
    • 73849123750 scopus 로고    scopus 로고
    • The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma
    • O'Connell MP, Fiori JL, Xu M, Carter AD, Frank BP, Camilli TC, et al (2010) The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. Oncogene 29: 34-44.
    • (2010) Oncogene , vol.29 , pp. 34-44
    • O'Connell, M.P.1    Fiori, J.L.2    Xu, M.3    Carter, A.D.4    Frank, B.P.5    Camilli, T.C.6
  • 23
    • 0030999606 scopus 로고    scopus 로고
    • A novel drosophila receptor tyrosine kinase expressed specifically in the nervous system. Unique structural features and implication in developmental signaling
    • Oishi I, Sugiyama S, Liu ZJ, Yamamura H, Nishida Y, Minami Y, (1997) A novel drosophila receptor tyrosine kinase expressed specifically in the nervous system. Unique structural features and implication in developmental signaling. J Biol Chem 272: 11916-11923.
    • (1997) J Biol Chem , vol.272 , pp. 11916-11923
    • Oishi, I.1    Sugiyama, S.2    Liu, Z.J.3    Yamamura, H.4    Nishida, Y.5    Minami, Y.6
  • 24
    • 10744219743 scopus 로고    scopus 로고
    • The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway
    • Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B, et al (2003) The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells 8: 645-654.
    • (2003) Genes Cells , vol.8 , pp. 645-654
    • Oishi, I.1    Suzuki, H.2    Onishi, N.3    Takada, R.4    Kani, S.5    Ohkawara, B.6
  • 25
    • 0034009511 scopus 로고    scopus 로고
    • Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B
    • Oldridge M, Fortuna AM, Maringa M, Propping P, Mansour S, Pollitt C, et al (2000) Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B. Nat Genet 24: 275-278.
    • (2000) Nat Genet , vol.24 , pp. 275-278
    • Oldridge, M.1    Fortuna, A.M.2    Maringa, M.3    Propping, P.4    Mansour, S.5    Pollitt, C.6
  • 26
    • 19544375032 scopus 로고    scopus 로고
    • Wnt control of stem cells and differentiation in the intestinal epithelium
    • Pinto D, Clevers H, (2005) Wnt control of stem cells and differentiation in the intestinal epithelium. Exp Cell Res 306: 357-363.
    • (2005) Exp Cell Res , vol.306 , pp. 357-363
    • Pinto, D.1    Clevers, H.2
  • 27
    • 0031596806 scopus 로고    scopus 로고
    • Identification of a frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases
    • Saldanha J, Singh J, Mahadevan D, (1998) Identification of a frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases. Protein Sci 7: 1632-1635.
    • (1998) Protein Sci , vol.7 , pp. 1632-1635
    • Saldanha, J.1    Singh, J.2    Mahadevan, D.3
  • 28
    • 0043234811 scopus 로고    scopus 로고
    • Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation
    • Topol L, Jiang X, Choi H, Garrett-Beal L, Carolan PJ, Yang Y, (2003) Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation. J Cell Biol 162: 899-908.
    • (2003) J Cell Biol , vol.162 , pp. 899-908
    • Topol, L.1    Jiang, X.2    Choi, H.3    Garrett-Beal, L.4    Carolan, P.J.5    Yang, Y.6
  • 29
    • 0029939701 scopus 로고    scopus 로고
    • Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development
    • Torres MA, Yang-Snyder JA, Purcell SM, DeMarais AA, McGrew LL, Moon RT, (1996) Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development. J Cell Biol 133: 1123-1137.
    • (1996) J Cell Biol , vol.133 , pp. 1123-1137
    • Torres, M.A.1    Yang-Snyder, J.A.2    Purcell, S.M.3    Demarais, A.A.4    McGrew, L.L.5    Moon, R.T.6
  • 30
    • 67650429679 scopus 로고    scopus 로고
    • Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma
    • Wright TM, Brannon AR, Gordan JD, Mikels AJ, Mitchell C, Chen S, et al (2009) Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma. Oncogene 28: 2513-2523.
    • (2009) Oncogene , vol.28 , pp. 2513-2523
    • Wright, T.M.1    Brannon, A.R.2    Gordan, J.D.3    Mikels, A.J.4    Mitchell, C.5    Chen, S.6
  • 31
    • 0036166289 scopus 로고    scopus 로고
    • JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates
    • Yamanaka H, Moriguchi T, Masuyama N, Kusakabe M, Hanafusa H, Takada R, et al (2002) JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates. EMBO Rep 3: 69-75.
    • (2002) EMBO Rep , vol.3 , pp. 69-75
    • Yamanaka, H.1    Moriguchi, T.2    Masuyama, N.3    Kusakabe, M.4    Hanafusa, H.5    Takada, R.6


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