메뉴 건너뛰기




Volumn 28, Issue 36, 2009, Pages 3197-3208

Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling

Author keywords

Invadopodia; MMP 13; Osteosarcoma; Ror2; Wnt5a

Indexed keywords

ALPHA TUBULIN; COLLAGENASE 3; GREEN FLUORESCENT PROTEIN; MATRIGEL; PROTEIN TYROSINE KINASE; ROR2 ENZYME; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; WNT5A PROTEIN; YELLOW FLUORESCENT PROTEIN;

EID: 70349101267     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.175     Document Type: Article
Times cited : (157)

References (34)
  • 1
    • 46749088657 scopus 로고    scopus 로고
    • The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src
    • Akbarzadeh S, Wheldon LM, Sweet SM, Talma S, Mardakheh FK, Heath JK. (2008). The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src. PLoS ONE 3: e1873.
    • (2008) PLoS ONE , vol.3
    • Akbarzadeh, S.1    Wheldon, L.M.2    Sweet, S.M.3    Talma, S.4    Mardakheh, F.K.5    Heath, J.K.6
  • 2
    • 0031761892 scopus 로고    scopus 로고
    • Tumor and endothelial cell invasion of basement membranes
    • Albini A. (1998). Tumor and endothelial cell invasion of basement membranes. The matrigel chemoinvasion assay as a tool for dissecting molecular mechanisms. Pathol Oncol Res 4: 230-241.
    • (1998) Pathol Oncol Res , vol.4 , pp. 230-241
    • Albini, A.1
  • 3
    • 0033527066 scopus 로고    scopus 로고
    • An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation
    • Bowden ET, Barth M, Thomas D, Glazer RI, Mueller SC. (1999). An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation. Oncogene 18: 4440-4449.
    • (1999) Oncogene , vol.18 , pp. 4440-4449
    • Bowden, E.T.1    Barth, M.2    Thomas, D.3    Glazer, R.I.4    Mueller, S.C.5
  • 4
    • 40849120593 scopus 로고    scopus 로고
    • Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion
    • Cortesio CL, Chan KT, Perrin BJ, Burton NO, Zhang S, Zhang ZY et al. (2008). Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion. J Cell Biol 180: 957-971.
    • (2008) J Cell Biol , vol.180 , pp. 957-971
    • Cortesio, C.L.1    Chan, K.T.2    Perrin, B.J.3    Burton, N.O.4    Zhang, S.5    Zhang, Z.Y.6
  • 5
    • 33846651513 scopus 로고    scopus 로고
    • A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma
    • Dass CR, Ek ET, Contreras KG, Choong PF. (2006). A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma. Clin Exp Metastasis 23: 367-380.
    • (2006) Clin Exp Metastasis , vol.23 , pp. 367-380
    • Dass, C.R.1    Ek, E.T.2    Contreras, K.G.3    Choong, P.F.4
  • 6
    • 27144450534 scopus 로고    scopus 로고
    • Wnt-5a protein expression in primary dukes B colon cancers identifies a subgroup of patients with good prognosis
    • Dejmek J, Dejmek A, Safholm A, Sjolander A, Andersson T. (2005). Wnt-5a protein expression in primary dukes B colon cancers identifies a subgroup of patients with good prognosis. Cancer Res 65 : 9142-9146.
    • (2005) Cancer Res , vol.65 , pp. 9142-9146
    • Dejmek, J.1    Dejmek, A.2    Safholm, A.3    Sjolander, A.4    Andersson, T.5
  • 7
    • 2442680430 scopus 로고    scopus 로고
    • Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
    • Gonzalez-Sancho JM, Brennan KR, Castelo-Soccio LA, Brown AM. (2004). Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin. Mol Cell Biol 24: 4757-4768.
    • (2004) Mol Cell Biol , vol.24 , pp. 4757-4768
    • Gonzalez-Sancho, J.M.1    Brennan, K.R.2    Castelo-Soccio, L.A.3    Brown, A.M.4
  • 8
    • 50649124475 scopus 로고    scopus 로고
    • Dominant negative LRP5 decreases tumorigenicity and metastasis of osteosarcoma in an animal model
    • Guo Y, Rubin EM, Xie J, Zi X, Hoang BH. (2008). Dominant negative LRP5 decreases tumorigenicity and metastasis of osteosarcoma in an animal model. Clin Orthop Relat Res 466: 2039-2045.
    • (2008) Clin Orthop Relat Res , vol.466 , pp. 2039-2045
    • Guo, Y.1    Rubin, E.M.2    Xie, J.3    Zi, X.4    Hoang, B.H.5
  • 9
    • 59749093869 scopus 로고    scopus 로고
    • Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development
    • He F, Xiong W, Yu X, Espinoza-Lewis R, Liu C, Gu S et al. (2008). Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development. Development 135: 3871-3879.
    • (2008) Development , vol.135 , pp. 3871-3879
    • He, F.1    Xiong, W.2    Yu, X.3    Espinoza-Lewis, R.4    Liu, C.5    Gu, S.6
  • 10
    • 9244240664 scopus 로고    scopus 로고
    • Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway
    • Hoang BH, Kubo T, Healey JH, Yang R, Nathan SS, Kolb EA et al. (2004). Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway. Cancer Res 64: 2734-2739.
    • (2004) Cancer Res , vol.64 , pp. 2734-2739
    • Hoang, B.H.1    Kubo, T.2    Healey, J.H.3    Yang, R.4    Nathan, S.S.5    Kolb, E.A.6
  • 11
    • 0029096787 scopus 로고
    • Aberrant expression of the growth factor Wnt-5A in human malignancy
    • Iozzo RV, Eichstetter I, Danielson KG. (1995). Aberrant expression of the growth factor Wnt-5A in human malignancy. Cancer Res 55: 3495-3499.
    • (1995) Cancer Res , vol.55 , pp. 3495-3499
    • Iozzo, R.V.1    Eichstetter, I.2    Danielson, K.G.3
  • 12
    • 9644290911 scopus 로고    scopus 로고
    • The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon
    • Kani S, Oishi I, Yamamoto H, Yoda A, Suzuki H, Nomachi A et al. (2004). The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon. J Biol Chem 279: 50102-50109.
    • (2004) J Biol Chem , vol.279 , pp. 50102-50109
    • Kani, S.1    Oishi, I.2    Yamamoto, H.3    Yoda, A.4    Suzuki, H.5    Nomachi, A.6
  • 13
    • 7244224817 scopus 로고    scopus 로고
    • Coordinating cytoskeletal tracks to polarize cellular movements
    • Kodama A, Lechler T, Fuchs E. (2004). Coordinating cytoskeletal tracks to polarize cellular movements. J Cell Biol 167: 203-207.
    • (2004) J Cell Biol , vol.167 , pp. 203-207
    • Kodama, A.1    Lechler, T.2    Fuchs, E.3
  • 15
    • 33751295132 scopus 로고    scopus 로고
    • Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion
    • Kurayoshi M, Oue N, Yamamoto H, Kishida M, Inoue A, Asahara T et al. (2006). Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. Cancer Res 66: 10439-10448.
    • (2006) Cancer Res , vol.66 , pp. 10439-10448
    • Kurayoshi, M.1    Oue, N.2    Yamamoto, H.3    Kishida, M.4    Inoue, A.5    Asahara, T.6
  • 16
    • 0345356929 scopus 로고    scopus 로고
    • Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
    • Liang H, Chen Q, Coles AH, Anderson SJ, Pihan G, Bradley A et al. (2003). Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue. Cancer Cell 4: 349-360.
    • (2003) Cancer Cell , vol.4 , pp. 349-360
    • Liang, H.1    Chen, Q.2    Coles, A.H.3    Anderson, S.J.4    Pihan, G.5    Bradley, A.6
  • 17
    • 33845398385 scopus 로고    scopus 로고
    • Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2
    • Masckauchan TN, Agalliu D, Vorontchikhina M, Ahn A, Parmalee NL, Li CM et al. (2006). Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2. Mol Biol Cell 17: 5163-5172.
    • (2006) Mol Biol Cell , vol.17 , pp. 5163-5172
    • Masckauchan, T.N.1    Agalliu, D.2    Vorontchikhina, M.3    Ahn, A.4    Parmalee, N.L.5    Li, C.M.6
  • 18
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • Mikels AJ, Nusse R. (2006). Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 4: e115.
    • (2006) PLoS Biol , vol.4
    • Mikels, A.J.1    Nusse, R.2
  • 19
    • 33751215213 scopus 로고    scopus 로고
    • Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration
    • Nishita M, Yoo SK, Nomachi A, Kani S, Sougawa N, Ohta Y et al. (2006). Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration. J Cell Biol 175: 555-562.
    • (2006) J Cell Biol , vol.175 , pp. 555-562
    • Nishita, M.1    Yoo, S.K.2    Nomachi, A.3    Kani, S.4    Sougawa, N.5    Ohta, Y.6
  • 20
    • 54249099723 scopus 로고    scopus 로고
    • Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A
    • Nomachi A, Nishita M, Inaba D, Enomoto M, Hamasaki M, Minami Y. (2008). Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A. J Biol Chem 283: 27973-27981.
    • (2008) J Biol Chem , vol.283 , pp. 27973-27981
    • Nomachi, A.1    Nishita, M.2    Inaba, D.3    Enomoto, M.4    Hamasaki, M.5    Minami, Y.6
  • 21
    • 10744219743 scopus 로고    scopus 로고
    • The receptor tyrosine kinase Ror2 is involved in noncanonical Wnt5a/JNK signalling pathway
    • Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B et al. (2003). The receptor tyrosine kinase Ror2 is involved in noncanonical Wnt5a/JNK signalling pathway. Genes Cells 8: 645-654.
    • (2003) Genes Cells , vol.8 , pp. 645-654
    • Oishi, I.1    Suzuki, H.2    Onishi, N.3    Takada, R.4    Kani, S.5    Ohkawara, B.6
  • 22
    • 0031846665 scopus 로고    scopus 로고
    • Antisense wnt-5a mimics wnt-1-mediated C57MG mammary epithelial cell transformation
    • Olson DJ, Gibo DM. (1998). Antisense wnt-5a mimics wnt-1-mediated C57MG mammary epithelial cell transformation. Exp Cell Res 241: 134-141.
    • (1998) Exp Cell Res , vol.241 , pp. 134-141
    • Olson, D.J.1    Gibo, D.M.2
  • 23
    • 43449088823 scopus 로고    scopus 로고
    • The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src
    • Oneyama C, Hikita T, Enya K, Dobenecker MW, Saito K, Nada S et al. (2008). The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src. Mol Cell 30: 426-436.
    • (2008) Mol Cell , vol.30 , pp. 426-436
    • Oneyama, C.1    Hikita, T.2    Enya, K.3    Dobenecker, M.W.4    Saito, K.5    Nada, S.6
  • 24
    • 20144386716 scopus 로고    scopus 로고
    • Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities
    • Onodera Y, Hashimoto S, Hashimoto A, Morishige M, Mazaki Y, Yamada A et al. (2005). Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities. EMBO J 24: 963-973.
    • (2005) EMBO J , vol.24 , pp. 963-973
    • Onodera, Y.1    Hashimoto, S.2    Hashimoto, A.3    Morishige, M.4    Mazaki, Y.5    Yamada, A.6
  • 25
    • 33645774667 scopus 로고    scopus 로고
    • Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines
    • Pukrop T, Klemm F, Hagemann T, Gradl D, Schulz M, Siemes S et al. (2006). Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines. Proc Natl Acad Sci USA 103: 5454-5459.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5454-5459
    • Pukrop, T.1    Klemm, F.2    Hagemann, T.3    Gradl, D.4    Schulz, M.5    Siemes, S.6
  • 27
    • 34547604466 scopus 로고    scopus 로고
    • Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity
    • Schlessinger K, McManus EJ, Hall A. (2007). Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity. J Cell Biol 178: 355-361.
    • (2007) J Cell Biol , vol.178 , pp. 355-361
    • Schlessinger, K.1    McManus, E.J.2    Hall, A.3
  • 28
    • 15244360639 scopus 로고    scopus 로고
    • Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation
    • Schulte G, Bryja V, Rawal N, Castelo-Branco G, Sousa KM, Arenas E. (2005). Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. J Neurochem 92 : 1550-1553.
    • (2005) J Neurochem , vol.92 , pp. 1550-1553
    • Schulte, G.1    Bryja, V.2    Rawal, N.3    Castelo-Branco, G.4    Sousa, K.M.5    Arenas, E.6
  • 29
    • 19944426775 scopus 로고    scopus 로고
    • Altered endochondral bone development in matrix metalloproteinase 13-deficient mice
    • Stickens D, Behonick DJ, Ortega N, Heyer B, Hartenstein B, Yu Y et al. (2004). Altered endochondral bone development in matrix metalloproteinase 13-deficient mice. Development 131: 5883-5895.
    • (2004) Development , vol.131 , pp. 5883-5895
    • Stickens, D.1    Behonick, D.J.2    Ortega, N.3    Heyer, B.4    Hartenstein, B.5    Yu, Y.6
  • 30
    • 6744265274 scopus 로고    scopus 로고
    • Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation
    • Takeuchi S, Takeda K, Oishi I, Nomi M, Ikeya M, Itoh K et al. (2000). Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation. Genes Cells 5: 71-78.
    • (2000) Genes Cells , vol.5 , pp. 71-78
    • Takeuchi, S.1    Takeda, K.2    Oishi, I.3    Nomi, M.4    Ikeya, M.5    Itoh, K.6
  • 31
    • 33748979745 scopus 로고    scopus 로고
    • Invadopodia: Specialized cell structures for cancer invasion
    • Weaver AM. (2006). Invadopodia: specialized cell structures for cancer invasion. Clin Exp Metastasis 23: 97-105.
    • (2006) Clin Exp Metastasis , vol.23 , pp. 97-105
    • Weaver, A.M.1
  • 33
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz A, Nusse R. (1998). Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 14: 59-88.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 34
    • 46049083566 scopus 로고    scopus 로고
    • Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex
    • Yamamoto S, Nishimura O, Misaki K, Nishita M, Minami Y, Yonemura S et al. (2008). Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell 15: 23-36.
    • (2008) Dev Cell , vol.15 , pp. 23-36
    • Yamamoto, S.1    Nishimura, O.2    Misaki, K.3    Nishita, M.4    Minami, Y.5    Yonemura, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.