메뉴 건너뛰기




Volumn 124, Issue 6, 2014, Pages 2523-2537

KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; DNA; DOXORUBICIN; KRUPPEL LIKE FACTOR 4; NEPHRIN;

EID: 84902166317     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI69557     Document Type: Article
Times cited : (103)

References (49)
  • 1
    • 0034532675 scopus 로고    scopus 로고
    • The biology of the mammalian Kruppel-like family of transcription factors
    • Dang DT, Pevsner J, Yang VW. The biology of the mammalian Kruppel-like family of transcription factors. Int J Biochem Cell Biol. 2000;32(11-12):1103- 1121.
    • (2000) Int J Biochem Cell Biol. , vol.32 , Issue.11-12 , pp. 1103-1121
    • Dang, D.T.1    Pevsner, J.2    Yang, V.W.3
  • 2
    • 0036340041 scopus 로고    scopus 로고
    • The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
    • Katz JP, et al. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development. 2002;129(11):2619-2628.
    • (2002) Development. , vol.129 , Issue.11 , pp. 2619-2628
    • Katz, J.P.1
  • 3
    • 0032813661 scopus 로고    scopus 로고
    • Klf4 is a transcription factor required for establishing the barrier function of the skin
    • Segre JA, Bauer C, Fuchs E. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat Genet. 1999;22(4):356-360.
    • (1999) Nat Genet. , vol.22 , Issue.4 , pp. 356-360
    • Segre, J.A.1    Bauer, C.2    Fuchs, E.3
  • 4
    • 34250216304 scopus 로고    scopus 로고
    • The diverse functions of Kruppel-like factors 4 and 5 in epithelial biology and pathobiology
    • McConnell BB, Ghaleb AM, Nandan MO, Yang VW. The diverse functions of Kruppel-like factors 4 and 5 in epithelial biology and pathobiology. Bioessays. 2007;29(6):549-557.
    • (2007) Bioessays. , vol.29 , Issue.6 , pp. 549-557
    • McConnell, B.B.1    Ghaleb, A.M.2    Nandan, M.O.3    Yang, V.W.4
  • 5
    • 17644391337 scopus 로고    scopus 로고
    • Combinatorial control of the bradykinin B2 receptor promoter by p53, CREB, KLF-4, and CBP: Implications for terminal nephron differentiation
    • Saifudeen Z, Dipp S, Fan H, El-Dahr SS. Combinatorial control of the bradykinin B2 receptor promoter by p53, CREB, KLF-4, and CBP: implications for terminal nephron differentiation. Am J Physiol. 2005;288(5):F899-F909.
    • (2005) Am J Physiol. , vol.288 , Issue.5
    • Saifudeen, Z.1    Dipp, S.2    Fan, H.3    El-Dahr, S.S.4
  • 6
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126(4):663-676.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 7
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131(5):861-872.
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1
  • 8
    • 50849142559 scopus 로고    scopus 로고
    • A high-efficiency system for the generation and study of human induced pluripotent stem cells
    • Maherali N, Ahfeldt T, Rigamonti A, Utikal J, Cowan C, Hochedlinger K. A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell. 2008;3(3):340-345.
    • (2008) Cell Stem Cell , vol.3 , Issue.3 , pp. 340-345
    • Maherali, N.1    Ahfeldt, T.2    Rigamonti, A.3    Utikal, J.4    Cowan, C.5    Hochedlinger, K.6
  • 9
    • 41949134533 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from adult mouse liver and stomach cells
    • Aoi T, et al. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science. 2008;321(5889):699-702.
    • (2008) Science , vol.321 , Issue.5889 , pp. 699-702
    • Aoi, T.1
  • 10
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol. 2008;26(1):101-106.
    • (2008) Nat Biotechnol. , vol.26 , Issue.1 , pp. 101-106
    • Nakagawa, M.1
  • 11
    • 37549008674 scopus 로고    scopus 로고
    • C-Myc is dispensable for direct reprogramming of mouse fibroblasts
    • Wernig M, Meissner A, Cassady JP, Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell. 2008;2(1):10-12.
    • (2008) Cell Stem Cell , vol.2 , Issue.1 , pp. 10-12
    • Wernig, M.1    Meissner, A.2    Cassady, J.P.3    Jaenisch, R.4
  • 12
    • 77957551870 scopus 로고    scopus 로고
    • A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • Li R, et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell. 2010;7(1):51-63.
    • (2010) Cell Stem Cell , vol.7 , Issue.1 , pp. 51-63
    • Li, R.1
  • 13
    • 77953683141 scopus 로고    scopus 로고
    • Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2
    • Hayashi K, Sasamura H, Ishiguro K, Sakamaki Y, Azegami T, Itoh H. Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2. Kidney Int. 2010;78(1):69-78.
    • (2010) Kidney Int. , vol.78 , Issue.1 , pp. 69-78
    • Hayashi, K.1    Sasamura, H.2    Ishiguro, K.3    Sakamaki, Y.4    Azegami, T.5    Itoh, H.6
  • 14
    • 0033802098 scopus 로고    scopus 로고
    • Progressive adriamycin nephropathy in mice: Sequence of histologic and immunohistochemical events
    • Wang Y, Wang YP, Tay YC, Harris DC. Progressive adriamycin nephropathy in mice: sequence of histologic and immunohistochemical events. Kidney Int. 2000;58(4):1797-1804.
    • (2000) Kidney Int. , vol.58 , Issue.4 , pp. 1797-1804
    • Wang, Y.1    Wang, Y.P.2    Tay, Y.C.3    Harris, D.C.4
  • 16
    • 77955877135 scopus 로고    scopus 로고
    • Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria
    • Dai C, Saleem MA, Holzman LB, Mathieson P, Liu Y. Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria. Kidney Int. 2010;77(11):962-973.
    • (2010) Kidney Int. , vol.77 , Issue.11 , pp. 962-973
    • Dai, C.1    Saleem, M.A.2    Holzman, L.B.3    Mathieson, P.4    Liu, Y.5
  • 17
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    • Liu F, Song Y, Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther. 1999;6(7):1258-1266.
    • (1999) Gene Ther. , vol.6 , Issue.7 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 18
    • 80053377598 scopus 로고    scopus 로고
    • Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glomerular podocytes
    • Bu X, et al. Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glomerular podocytes. Am J Physiol. 2011;301(4):F784-F792.
    • (2011) Am J Physiol. , vol.301 , Issue.4
    • Bu, X.1
  • 19
    • 84861748655 scopus 로고    scopus 로고
    • Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation
    • Mallipattu SK, et al. Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation. J Biol Chem. 2012;287(23):19122-19135.
    • (2012) J Biol Chem. , vol.287 , Issue.23 , pp. 19122-19135
    • Mallipattu, S.K.1
  • 20
    • 0032004389 scopus 로고    scopus 로고
    • Identification of the DNA sequence that interacts with the gut-enriched Kruppel-like factor
    • Shields JM, Yang VW. Identification of the DNA sequence that interacts with the gut-enriched Kruppel-like factor. Nucleic Acids Res. 1998;26(3):796-802.
    • (1998) Nucleic Acids Res. , vol.26 , Issue.3 , pp. 796-802
    • Shields, J.M.1    Yang, V.W.2
  • 21
    • 80053519863 scopus 로고    scopus 로고
    • Valproic acid attenuates proteinuria and kidney injury
    • Van Beneden K, et al. Valproic acid attenuates proteinuria and kidney injury. J Am Soc Nephrol. 2011;22(10):1863-1875.
    • (2011) J Am Soc Nephrol. , vol.22 , Issue.10 , pp. 1863-1875
    • Van Beneden, K.1
  • 22
    • 77949777194 scopus 로고    scopus 로고
    • Kruppel-like factor 4 is widely expressed in the mouse male and female reproductive tract and responds as an immediate early gene to activation of the protein kinase A in TM4 Sertoli cells
    • Godmann M, Kosan C, Behr R. Kruppel-like factor 4 is widely expressed in the mouse male and female reproductive tract and responds as an immediate early gene to activation of the protein kinase A in TM4 Sertoli cells. Reproduction. 2010;139(4):771-782.
    • (2010) Reproduction. , vol.139 , Issue.4 , pp. 771-782
    • Godmann, M.1    Kosan, C.2    Behr, R.3
  • 23
    • 77957922334 scopus 로고    scopus 로고
    • Kruppellike factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation
    • Kaushik DK, Gupta M, Das S, Basu A. Kruppellike factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation. J Neuroinflammation. 2010;7:68.
    • (2010) J Neuroinflammation. , vol.7 , pp. 68
    • Kaushik, D.K.1    Gupta, M.2    Das, S.3    Basu, A.4
  • 24
    • 58149504280 scopus 로고    scopus 로고
    • Adriamycin alters glomerular endothelium to induce proteinuria
    • Jeansson M, Bjorck K, Tenstad O, Haraldsson B. Adriamycin alters glomerular endothelium to induce proteinuria. J Am Soc Nephrol. 2009;20(1):114-122.
    • (2009) J Am Soc Nephrol. , vol.20 , Issue.1 , pp. 114-122
    • Jeansson, M.1    Bjorck, K.2    Tenstad, O.3    Haraldsson, B.4
  • 25
    • 42149122041 scopus 로고    scopus 로고
    • Properties of the glomerular barrier and mechanisms of proteinuria
    • Haraldsson B, Nystrom J, Deen WM. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev. 2008;88(2):451-487.
    • (2008) Physiol Rev. , vol.88 , Issue.2 , pp. 451-487
    • Haraldsson, B.1    Nystrom, J.2    Deen, W.M.3
  • 26
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature. 2007;447(7143):425-432.
    • (2007) Nature , vol.447 , Issue.7143 , pp. 425-432
    • Reik, W.1
  • 27
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol. 2010;28(10):1057-1068.
    • (2010) Nat Biotechnol. , vol.28 , Issue.10 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 28
    • 77950965653 scopus 로고    scopus 로고
    • Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes
    • Mali P, et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells. 2010;28(4):713-720.
    • (2010) Stem Cells , vol.28 , Issue.4 , pp. 713-720
    • Mali, P.1
  • 29
    • 33947368681 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines
    • Ou JN, et al. Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. Biochem Pharmacol. 2007;73(9):1297-1307.
    • (2007) Biochem Pharmacol. , vol.73 , Issue.9 , pp. 1297-1307
    • Ou, J.N.1
  • 30
    • 84855854046 scopus 로고    scopus 로고
    • Chronic kidney disease
    • Levey AS, Coresh J. Chronic kidney disease. Lancet. 2012;379(9811):165- 180.
    • (2012) Lancet , vol.379 , Issue.9811 , pp. 165-180
    • Levey, A.S.1    Coresh, J.2
  • 31
    • 0141468244 scopus 로고    scopus 로고
    • Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention
    • Sarnak MJ, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation. 2003;108(17):2154- 2169.
    • (2003) Circulation , vol.108 , Issue.17 , pp. 2154-2169
    • Sarnak, M.J.1
  • 32
    • 84870542457 scopus 로고    scopus 로고
    • Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice
    • Zhou G, et al. Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice. J Clin Invest. 2012;122(12):4727-4731.
    • (2012) J Clin Invest. , vol.122 , Issue.12 , pp. 4727-4731
    • Zhou, G.1
  • 33
    • 84885067891 scopus 로고    scopus 로고
    • Kruppel-like factor 15 is critical for vascular inflammation
    • Lu Y, et al. Kruppel-like factor 15 is critical for vascular inflammation. J Clin Invest. 2013;123(10):4232-4241.
    • (2013) J Clin Invest. , vol.123 , Issue.10 , pp. 4232-4241
    • Lu, Y.1
  • 34
    • 77953713216 scopus 로고    scopus 로고
    • Kruppel-like factor 4 regulates pressure-induced cardiac hypertrophy
    • Liao X, et al. Kruppel-like factor 4 regulates pressure-induced cardiac hypertrophy. J Mol Cell Cardiol. 2010;49(2):334-338.
    • (2010) J Mol Cell Cardiol. , vol.49 , Issue.2 , pp. 334-338
    • Liao, X.1
  • 35
    • 0037947656 scopus 로고    scopus 로고
    • Diabetic kidney disease in the db/db mouse
    • Sharma K, McCue P, Dunn SR. Diabetic kidney disease in the db/db mouse. Am J Physiol. 2003;284(6):F1138-F1144.
    • (2003) Am J Physiol. , vol.284 , Issue.6
    • Sharma, K.1    McCue, P.2    Dunn, S.R.3
  • 36
    • 77955875400 scopus 로고    scopus 로고
    • Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes
    • Deb DK, et al. Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes. Kidney Int. 2010;77(11):1000-1009.
    • (2010) Kidney Int. , vol.77 , Issue.11 , pp. 1000-1009
    • Deb, D.K.1
  • 37
  • 38
    • 58149384447 scopus 로고    scopus 로고
    • "Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension
    • Ishiguro K, Hayashi K, Sasamura H, Sakamaki Y, Itoh H. "Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension. Hypertension. 2009;53(1):83-89.
    • (2009) Hypertension , vol.53 , Issue.1 , pp. 83-89
    • Ishiguro, K.1    Hayashi, K.2    Sasamura, H.3    Sakamaki, Y.4    Itoh, H.5
  • 39
    • 33749011145 scopus 로고    scopus 로고
    • Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation
    • Sohara E, et al. Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation. Proc Natl Acad Sci U S A. 2006;103(38):14217-14222.
    • (2006) Proc Natl Acad Sci U S A. , vol.103 , Issue.38 , pp. 14217-14222
    • Sohara, E.1
  • 40
    • 77954599877 scopus 로고    scopus 로고
    • Inhibition of podocyte FAK protects against proteinuria and foot process effacement
    • Ma H, et al. Inhibition of podocyte FAK protects against proteinuria and foot process effacement. J Am Soc Nephrol. 2010;21(7):1145-1156.
    • (2010) J Am Soc Nephrol. , vol.21 , Issue.7 , pp. 1145-1156
    • Ma, H.1
  • 41
    • 77953530356 scopus 로고    scopus 로고
    • Beta-Catenin mediates adriamycin-induced albuminuria and podocyte injury in adult mouse kidneys
    • Heikkila E, et al. beta-Catenin mediates adriamycin-induced albuminuria and podocyte injury in adult mouse kidneys. Nephrol Dial Transplant. 2010;25(8):2437-2446.
    • (2010) Nephrol Dial Transplant. , vol.25 , Issue.8 , pp. 2437-2446
    • Heikkila, E.1
  • 42
    • 0034005452 scopus 로고    scopus 로고
    • Analysis of segmental renal gene expression by laser capture microdissection
    • Kohda Y, Murakami H, Moe OW, Star RA. Analysis of segmental renal gene expression by laser capture microdissection. Kidney Int. 2000;57(1):321-331.
    • (2000) Kidney Int. , vol.57 , Issue.1 , pp. 321-331
    • Kohda, Y.1    Murakami, H.2    Moe, O.W.3    Star, R.A.4
  • 43
    • 0036149243 scopus 로고    scopus 로고
    • Laser microdissection and gene expression analysis on formaldehyde-fixed archival tissue
    • Cohen CD, Grone HJ, Grone EF, Nelson PJ, Schlondorff D, Kretzler M. Laser microdissection and gene expression analysis on formaldehyde-fixed archival tissue. Kidney Int. 2002;61(1):125-132.
    • (2002) Kidney Int. , vol.61 , Issue.1 , pp. 125-132
    • Cohen, C.D.1    Grone, H.J.2    Grone, E.F.3    Nelson, P.J.4    Schlondorff, D.5    Kretzler, M.6
  • 44
    • 0036189998 scopus 로고    scopus 로고
    • A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression
    • Saleem MA, et al. A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol. 2002;13(3):630-638.
    • (2002) J Am Soc Nephrol. , vol.13 , Issue.3 , pp. 630-638
    • Saleem, M.A.1
  • 45
    • 1542349097 scopus 로고    scopus 로고
    • Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties
    • Satchell SC, Anderson KL, Mathieson PW. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties. J Am Soc Nephrol. 2004;15(3):566-574.
    • (2004) J Am Soc Nephrol. , vol.15 , Issue.3 , pp. 566-574
    • Satchell, S.C.1    Anderson, K.L.2    Mathieson, P.W.3
  • 46
    • 39549098861 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria
    • Li Y, Kang YS, Dai C, Kiss LP, Wen X, Liu Y. Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am J Pathol. 2008;172(2):299-308.
    • (2008) Am J Pathol. , vol.172 , Issue.2 , pp. 299-308
    • Li, Y.1    Kang, Y.S.2    Dai, C.3    Kiss, L.P.4    Wen, X.5    Liu, Y.6
  • 47
    • 22344443467 scopus 로고    scopus 로고
    • WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment
    • Rico M, et al. WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment. Am J Physiol. 2005;289(2):F431-F441.
    • (2005) Am J Physiol. , vol.289 , Issue.2
    • Rico, M.1
  • 48
    • 2342627322 scopus 로고    scopus 로고
    • Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration
    • Shimizu-Hirota R, Sasamura H, Kuroda M, Kobayashi E, Hayashi M, Saruta T. Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration. Circ Res. 2004;94(8):1067-1074.
    • (2004) Circ Res. , vol.94 , Issue.8 , pp. 1067-1074
    • Shimizu-Hirota, R.1    Sasamura, H.2    Kuroda, M.3    Kobayashi, E.4    Hayashi, M.5    Saruta, T.6
  • 49
    • 52649086692 scopus 로고    scopus 로고
    • KLF4 promotes the expression, translocation, and releas eof HMGB1 in RAW264.7 macrophages in response to LPS
    • Liu J, Liu Y, Zhang H, Chen G, Wang K, Xiao X. KLF4 promotes the expression, translocation, and releas eof HMGB1 in RAW264.7 macrophages in response to LPS. Shock. 2008;30(3):260-266.
    • (2008) Shock. , vol.30 , Issue.3 , pp. 260-266
    • Liu, J.1    Liu, Y.2    Zhang, H.3    Chen, G.4    Wang, K.5    Xiao, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.