메뉴 건너뛰기




Volumn 85, Issue 2, 2015, Pages 148-152

Is nonalcoholic fatty liver disease an endogenous alcoholic fatty liver disease? - A mechanistic hypothesis

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE; FATTY ACID ESTER;

EID: 84944358185     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2015.04.021     Document Type: Article
Times cited : (39)

References (88)
  • 1
    • 84858842467 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease
    • Polyzos SA, Kountouras J, Zavos C, Deretzi G. Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease. J Clin Gastroenterol 2012;46:272-84. http://dx.doi.org/10.1097/MCG.0b013e31824587-0
    • (2012) J Clin Gastroenterol , vol.46 , pp. 272-284
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3    Deretzi, G.4
  • 2
    • 0036780539 scopus 로고    scopus 로고
    • Other disease associations with non-alcoholic fatty liver disease (NAFLD)
    • Allard JP. Other disease associations with non-alcoholic fatty liver disease (NAFLD). Best Pract Res Clin Gastroenterol 2002;16:783-95. http://dx.doi.org/10.1053/bega.2002.0330.
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , pp. 783-795
    • Allard, J.P.1
  • 3
    • 67649990082 scopus 로고    scopus 로고
    • Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis
    • Syn WK, Teaberry V, Choi SS, Diehl AM. Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. Semin Liver Dis 2009;29:200-10.
    • (2009) Semin Liver Dis , vol.29 , pp. 200-210
    • Syn, W.K.1    Teaberry, V.2    Choi, S.S.3    Diehl, A.M.4
  • 4
    • 84925260735 scopus 로고    scopus 로고
    • Association between patatin-like phospholipase domain containing 3 gene (PNPLA3) polymorphisms and nonalcoholic fatty liver disease: a huge review and meta-analysis
    • Xu R, Tao A, Zhang S, Deng Y, Chen G. Association between patatin-like phospholipase domain containing 3 gene (PNPLA3) polymorphisms and nonalcoholic fatty liver disease: a huge review and meta-analysis. Sci Rep 2015;5:9284. http://dx.doi.org/10.1038/srep09284.
    • (2015) Sci Rep , vol.5 , pp. 9284
    • Xu, R.1    Tao, A.2    Zhang, S.3    Deng, Y.4    Chen, G.5
  • 5
    • 78751536418 scopus 로고    scopus 로고
    • Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians
    • Stickel F, Buch S, Lau K, Meyer zu Schwabedissen H, Berg T, Ridinger M, et al. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology 2011;53:86-95. http://dx.doi.org/10.1002/hep.24017.
    • (2011) Hepatology , vol.53 , pp. 86-95
    • Stickel, F.1    Buch, S.2    Lau, K.3    Meyer zu Schwabedissen, H.4    Berg, T.5    Ridinger, M.6
  • 6
    • 84873296091 scopus 로고    scopus 로고
    • Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH
    • Zhu L, Baker SS, Gill C, Liu W, Alkhouri R, Baker RD, et al. Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH. Hepatology 2013;57:601-9. http://dx.doi.org/10.1002/hep.26093.
    • (2013) Hepatology , vol.57 , pp. 601-609
    • Zhu, L.1    Baker, S.S.2    Gill, C.3    Liu, W.4    Alkhouri, R.5    Baker, R.D.6
  • 7
    • 0035045382 scopus 로고    scopus 로고
    • Obesity and female gender increase breath ethanol concentration: potential implications for the pathogenesis of nonalcoholic steatohepatitis
    • Nair S, Cope K, Risby TH, Diehl AM, Terence RH. Obesity and female gender increase breath ethanol concentration: potential implications for the pathogenesis of nonalcoholic steatohepatitis. Am J Gastroenterol 2001;96:1200-4. http://dx.doi.org/10.1111/j.1572-0241.2001.03702.x.
    • (2001) Am J Gastroenterol , vol.96 , pp. 1200-1204
    • Nair, S.1    Cope, K.2    Risby, T.H.3    Diehl, A.M.4    Terence, R.H.5
  • 8
    • 79959805522 scopus 로고    scopus 로고
    • Ursodeoxycholic acid dose-dependently improves liver injury in rats fed a methionine-and choline-deficient diet
    • Buko VU, Kuzmitskaya-Nikolaeva IA, Naruta EE, Lukivskaya OY, Kirko SN, Tauschel H-D. Ursodeoxycholic acid dose-dependently improves liver injury in rats fed a methionine-and choline-deficient diet. Hepatol Res 2011;41:647-59. http://dx.doi.org/10.1111/j.1872-034X.2011.00820.x.
    • (2011) Hepatol Res , vol.41 , pp. 647-659
    • Buko, V.U.1    Kuzmitskaya-Nikolaeva, I.A.2    Naruta, E.E.3    Lukivskaya, O.Y.4    Kirko, S.N.5    Tauschel, H.-D.6
  • 9
    • 77949677097 scopus 로고    scopus 로고
    • Role of alcohol metabolism in non-alcoholic steatohepatitis
    • Baker SS, Baker RD, Liu W, Nowak NJ, Zhu L. Role of alcohol metabolism in non-alcoholic steatohepatitis. PloS One 2010;5:e9570. http://dx.doi.org/10.1371/journal.pone.0009570.
    • (2010) PloS One , vol.5
    • Baker, S.S.1    Baker, R.D.2    Liu, W.3    Nowak, N.J.4    Zhu, L.5
  • 10
    • 0016793479 scopus 로고
    • Endogenous ethanol production and hepatic disease following jejunoileal bypass for morbid obesity
    • Mezey E, Imbembo AL, Potter JJ, Rent KC, Lombardo R, Holt PR. Endogenous ethanol production and hepatic disease following jejunoileal bypass for morbid obesity. Am J Clin Nutr 1975;28:1277-83.
    • (1975) Am J Clin Nutr , vol.28 , pp. 1277-1283
    • Mezey, E.1    Imbembo, A.L.2    Potter, J.J.3    Rent, K.C.4    Lombardo, R.5    Holt, P.R.6
  • 11
    • 0022657702 scopus 로고
    • Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats
    • Baraona E, Julkunen R, Tannenbaum L, Lieber CS. Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats. Gastroenterology 1986;90:103-10.
    • (1986) Gastroenterology , vol.90 , pp. 103-110
    • Baraona, E.1    Julkunen, R.2    Tannenbaum, L.3    Lieber, C.S.4
  • 12
    • 0030923618 scopus 로고    scopus 로고
    • Intra-digestive fermentation in intestinal malabsorption syndromes: relations with elevated serum activity of gammaglutamyl-transpeptidase
    • Picot D, Lauvin R, Hellegouarc'h R [Intra-digestive fermentation in intestinal malabsorption syndromes: relations with elevated serum activity of gammaglutamyl-transpeptidase]. Gastroenterol Clin Biol 1997;21:562-6.
    • (1997) Gastroenterol Clin Biol , vol.21 , pp. 562-566
    • Picot, D.1    Lauvin, R.2    Hellegouarc'h, R.3
  • 14
    • 84881506662 scopus 로고    scopus 로고
    • Cytochrome P4502E1 inhibitor, chlormethiazole, decreases lipopolysaccharide-induced inflammation in rat Kupffer cells with ethanol treatment
    • Ye Q, Wang X, Wang Q, Xia M, Zhu Y, Lian F, et al. Cytochrome P4502E1 inhibitor, chlormethiazole, decreases lipopolysaccharide-induced inflammation in rat Kupffer cells with ethanol treatment. Hepatol Res 2013;43:1115-23. http://dx.doi.org/10.1111/hepr.12063.
    • (2013) Hepatol Res , vol.43 , pp. 1115-1123
    • Ye, Q.1    Wang, X.2    Wang, Q.3    Xia, M.4    Zhu, Y.5    Lian, F.6
  • 15
    • 84874110762 scopus 로고    scopus 로고
    • Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure
    • Swaminathan K, Clemens DL, Dey A. Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure. Life Sci 2013;92:325-36. http://dx.doi.org/10.1016/j.lfs.2012.12.014.
    • (2013) Life Sci , vol.92 , pp. 325-336
    • Swaminathan, K.1    Clemens, D.L.2    Dey, A.3
  • 17
    • 39849096127 scopus 로고    scopus 로고
    • Alcohol induced hepatic fibrosis: role of acetaldehyde
    • Mello T, Ceni E, Surrenti C, Galli A. Alcohol induced hepatic fibrosis: role of acetaldehyde. Mol Aspects Med 2008;29:17-21. http://dx.doi.org/10.1016/j.mam.2007.10.001.
    • (2008) Mol Aspects Med , vol.29 , pp. 17-21
    • Mello, T.1    Ceni, E.2    Surrenti, C.3    Galli, A.4
  • 18
    • 0030052919 scopus 로고    scopus 로고
    • Fatty acid ethyl ester synthase, an enzyme for nonoxidative ethanol metabolism, is present in serum after liver and pancreatic injury
    • Aleryani S, Kabakibi A, Cluette-Brown J, Laposata M. Fatty acid ethyl ester synthase, an enzyme for nonoxidative ethanol metabolism, is present in serum after liver and pancreatic injury. Clin Chem 1996;42:24-7.
    • (1996) Clin Chem , vol.42 , pp. 24-27
    • Aleryani, S.1    Kabakibi, A.2    Cluette-Brown, J.3    Laposata, M.4
  • 19
    • 33751253098 scopus 로고    scopus 로고
    • Metabolic basis of ethanol-induced hepatic and pancreatic injury in hepatic alcohol dehydrogenase deficient deer mice
    • Bhopale KK, Wu H, Boor PJ, Popov VL, Ansari GAS, Kaphalia BS. Metabolic basis of ethanol-induced hepatic and pancreatic injury in hepatic alcohol dehydrogenase deficient deer mice. Alcohol 2006;39:179-88. http://dx.doi.org/10.1016/j.alcohol.2006.09.005.
    • (2006) Alcohol , vol.39 , pp. 179-188
    • Bhopale, K.K.1    Wu, H.2    Boor, P.J.3    Popov, V.L.4    Ansari, G.A.S.5    Kaphalia, B.S.6
  • 20
    • 0029995165 scopus 로고    scopus 로고
    • Hepatotoxicity and absorption of extrahepatic acetaldehyde in rats
    • Matysiak-Budnik T, Jokelainen K, Kärkkäinen P, Mäkisalo H, Ohisalo J, Salaspuro M. Hepatotoxicity and absorption of extrahepatic acetaldehyde in rats. J Pathol 1996;178:469-74. http://dx.doi.org/10.1002/(SICI)1096-9896(199604)178:4<469::AID-PATH510>3.0.CO;2-9.
    • (1996) J Pathol , vol.178 , pp. 469-474
    • Matysiak-Budnik, T.1    Jokelainen, K.2    Kärkkäinen, P.3    Mäkisalo, H.4    Ohisalo, J.5    Salaspuro, M.6
  • 21
    • 0027210494 scopus 로고
    • Liver collagen of rats submitted to chronic intoxication with acetaldehyde
    • Bankowski E, Pawlicka E, Sobolewski K. Liver collagen of rats submitted to chronic intoxication with acetaldehyde. Mol Cell Biochem 1993;121:37-43.
    • (1993) Mol Cell Biochem , vol.121 , pp. 37-43
    • Bankowski, E.1    Pawlicka, E.2    Sobolewski, K.3
  • 22
    • 0022385842 scopus 로고
    • Acetaldehyde alone may initiate hepatocellular damage in acute alcoholic liver disease
    • Barry RE, McGivan JD. Acetaldehyde alone may initiate hepatocellular damage in acute alcoholic liver disease. Gut 1985;26:1065-9.
    • (1985) Gut , vol.26 , pp. 1065-1069
    • Barry, R.E.1    McGivan, J.D.2
  • 23
    • 0021140608 scopus 로고
    • Determination of endogenous ethanol in blood and breath by gas chromatography-mass spectrometry
    • Jones AW, Mårdh G, Anggård E. Determination of endogenous ethanol in blood and breath by gas chromatography-mass spectrometry. Pharmacol Biochem Behav 1983;18(Suppl 1):267-72.
    • (1983) Pharmacol Biochem Behav , vol.18 , pp. 267-272
    • Jones, A.W.1    Mårdh, G.2    Anggård, E.3
  • 24
    • 29144508524 scopus 로고    scopus 로고
    • A longitudinal study of ethanol and acetaldehyde in the exhaled breath of healthy volunteers using selected-ion flow-tube mass spectrometry
    • Turner C, Spanel P, Smith D. A longitudinal study of ethanol and acetaldehyde in the exhaled breath of healthy volunteers using selected-ion flow-tube mass spectrometry. Rapid Commun Mass Spectrom 2006;20:61-8. http://dx.doi.org/10.1002/rcm.2275.
    • (2006) Rapid Commun Mass Spectrom , vol.20 , pp. 61-68
    • Turner, C.1    Spanel, P.2    Smith, D.3
  • 25
    • 0014813667 scopus 로고
    • The physiological role of liver alcohol dehydrogenase
    • Krebs HA, Perkins JRC-P. The physiological role of liver alcohol dehydrogenase. Biochem J 1970;118:635-44.
    • (1970) Biochem J , vol.118 , pp. 635-644
    • Krebs, H.A.1    Perkins, J.R.C.-P.2
  • 26
    • 0034320252 scopus 로고    scopus 로고
    • Increased gastrointestinal ethanol production in obese mice. implications for fatty liver disease pathogenesis
    • Cope K, Risby T, Diehl AM. Increased gastrointestinal ethanol production in obese mice. implications for fatty liver disease pathogenesis. Gastroenterology 2000;119:1340-7.
    • (2000) Gastroenterology , vol.119 , pp. 1340-1347
    • Cope, K.1    Risby, T.2    Diehl, A.M.3
  • 27
    • 50049128311 scopus 로고    scopus 로고
    • The role of increased gastrointestinal alcohol production in patients with the metabolic syndrome: Implications for the pathogenesis of non-alcoholic fatty liver disease
    • Menezes CN, Raal F, Immelman A, Song E. The role of increased gastrointestinal alcohol production in patients with the metabolic syndrome: Implications for the pathogenesis of non-alcoholic fatty liver disease. J Endocrinol Metab Diabetes South Africa 2008;13:48-56.
    • (2008) J Endocrinol Metab Diabetes South Africa , vol.13 , pp. 48-56
    • Menezes, C.N.1    Raal, F.2    Immelman, A.3    Song, E.4
  • 28
    • 0016765944 scopus 로고
    • Enterotoxigenic intestinal bacteria in tropical sprue. III. Preliminary characterization of Klebsiella pneumoniae enterotoxin
    • Klipstein FA, Engert RF. Enterotoxigenic intestinal bacteria in tropical sprue. III. Preliminary characterization of Klebsiella pneumoniae enterotoxin. J Infect Dis 1975;132:200-3.
    • (1975) J Infect Dis , vol.132 , pp. 200-203
    • Klipstein, F.A.1    Engert, R.F.2
  • 29
    • 0015876114 scopus 로고
    • Distribution of ethanol in the human gastrointestinal tract
    • Halsted CH, Robles EA, Mezey E. Distribution of ethanol in the human gastrointestinal tract. Am J Clin Nutr 1973;26:831-4.
    • (1973) Am J Clin Nutr , vol.26 , pp. 831-834
    • Halsted, C.H.1    Robles, E.A.2    Mezey, E.3
  • 30
    • 84871570353 scopus 로고    scopus 로고
    • Systematic analysis of the gene expression in the livers of nonalcoholic steatohepatitis: implications on potential biomarkers and molecular pathological mechanism
    • Zhang Y, Baker SS, Baker RD, Zhu R, Zhu L. Systematic analysis of the gene expression in the livers of nonalcoholic steatohepatitis: implications on potential biomarkers and molecular pathological mechanism. PLoS One 2012;7:e51131. http://dx.doi.org/10.1371/journal.pone.0051131.
    • (2012) PLoS One , vol.7
    • Zhang, Y.1    Baker, S.S.2    Baker, R.D.3    Zhu, R.4    Zhu, L.5
  • 31
    • 84867921274 scopus 로고    scopus 로고
    • Alcohol metabolism
    • Cederbaum AI. Alcohol metabolism. Clin Liver Dis 2012;16:667-85. http://dx.doi.org/10.1016/j.cld.2012.08.002.
    • (2012) Clin Liver Dis , vol.16 , pp. 667-685
    • Cederbaum, A.I.1
  • 32
    • 33746324791 scopus 로고    scopus 로고
    • Standardization of alcohol calculations in research
    • Brick J. Standardization of alcohol calculations in research. Alcohol Clin Exp Res 2006;30:1276-87. http://dx.doi.org/10.1111/j.1530-0277.2006.00155.x.
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1276-1287
    • Brick, J.1
  • 33
    • 0020584474 scopus 로고
    • Uninterrupted prolonged ethanol oxidation as a main pathogenetic factor of alcoholic liver damage: evidence from a new liquid diet animal model
    • Lindros KO, Stowell L, Väänänen H, Sipponen P, Lamminsivu U, Pikkarainen P, et al. Uninterrupted prolonged ethanol oxidation as a main pathogenetic factor of alcoholic liver damage: evidence from a new liquid diet animal model. Liver 1983;3:79-91.
    • (1983) Liver , vol.3 , pp. 79-91
    • Lindros, K.O.1    Stowell, L.2    Väänänen, H.3    Sipponen, P.4    Lamminsivu, U.5    Pikkarainen, P.6
  • 34
    • 0034764545 scopus 로고    scopus 로고
    • Inhibition of alcohol dehydrogenase blocks enhanced Gi-protein expression following ethanol treatment in experimental hepatocellular carcinoma in vitro
    • Kovach SJ, Sitzmann JV, McKillop IH. Inhibition of alcohol dehydrogenase blocks enhanced Gi-protein expression following ethanol treatment in experimental hepatocellular carcinoma in vitro. Eur J Gastroenterol Hepatol 2001;13:1209-16.
    • (2001) Eur J Gastroenterol Hepatol , vol.13 , pp. 1209-1216
    • Kovach, S.J.1    Sitzmann, J.V.2    McKillop, I.H.3
  • 35
    • 84865459623 scopus 로고    scopus 로고
    • Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats
    • Dolai S, Liang T, Lam PP, Fernandez NA, Chidambaram S, Gaisano HY. Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats. Gastroenterology 2012;143:832-43. http://dx.doi.org/10.1053/j.gastro.2012.06.011.
    • (2012) Gastroenterology , vol.143 , pp. 832-843
    • Dolai, S.1    Liang, T.2    Lam, P.P.3    Fernandez, N.A.4    Chidambaram, S.5    Gaisano, H.Y.6
  • 36
    • 85124854801 scopus 로고    scopus 로고
    • Anatomy, histology, embryology, and developmental anomalies of the small and large intestine
    • Feldman M, Friedman LS, Brandt L, editors. 9th ed. Philadelphia, PA: Saunders Elsevier
    • Kahn EDF. Anatomy, histology, embryology, and developmental anomalies of the small and large intestine. In: Feldman M, Friedman LS, Brandt L, editors. Sleisenger Fordtran's Gastrointest. Liver Dis.-2 vol. set. 9th ed. Philadelphia, PA: Saunders Elsevier; 2010, p. 1615-40.
    • (2010) Sleisenger Fordtran's Gastrointest. Liver Dis.-set , vol.2 , pp. 1615-1640
    • Kahn, E.D.F.1
  • 37
    • 84944358092 scopus 로고
    • Fiber Deficiency and colonic tumors
    • Reilly RW, KJ, editor. 1st ed., Springer, US-Plenum Publishing Corporation
    • Burkitt D. Fiber Deficiency and colonic tumors. In: Reilly RW, KJ, editor. Fiber Defic. Colon. Disord. 1st ed., Springer, US-Plenum Publishing Corporation; 1975, p. 139-47. http://dx.doi.org/10.1007/978-1-4684-2172-9_11.
    • (1975) Fiber Defic. Colon. Disord , pp. 139-147
    • Burkitt, D.1
  • 38
    • 43349107591 scopus 로고    scopus 로고
    • High prevalence of small intestinal bacterial overgrowth in patients with morbid obesity: a contributor to severe hepatic steatosis
    • Sabate JM, Jouet P, Harnois F, Mechler C, Msika S, Grossin M, et al. High prevalence of small intestinal bacterial overgrowth in patients with morbid obesity: a contributor to severe hepatic steatosis. Obes Surg 2008;18:371-7.
    • (2008) Obes Surg , vol.18 , pp. 371-377
    • Sabate, J.M.1    Jouet, P.2    Harnois, F.3    Mechler, C.4    Msika, S.5    Grossin, M.6
  • 39
    • 79955597671 scopus 로고    scopus 로고
    • Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8
    • Shanab AA, Scully P, Crosbie O, Buckley M, O'Mahony L, Shanahan F, et al. Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8. Dig Dis Sci 2011;56:1524-34. http://dx.doi.org/10.1007/s10620-010-1447-3.
    • (2011) Dig Dis Sci , vol.56 , pp. 1524-1534
    • Shanab, A.A.1    Scully, P.2    Crosbie, O.3    Buckley, M.4    O'Mahony, L.5    Shanahan, F.6
  • 40
    • 84902550631 scopus 로고    scopus 로고
    • Intestinal permeability is increased in children with non-alcoholic fatty liver disease, and correlates with liver disease severity
    • Giorgio V, Miele L, Principessa L, Ferretti F, Villa MP, Negro V, et al. Intestinal permeability is increased in children with non-alcoholic fatty liver disease, and correlates with liver disease severity. Dig Liver Dis 2014;46:556-60. http://dx.doi.org/10.1016/j.dld.2014.02.010.
    • (2014) Dig Liver Dis , vol.46 , pp. 556-560
    • Giorgio, V.1    Miele, L.2    Principessa, L.3    Ferretti, F.4    Villa, M.P.5    Negro, V.6
  • 41
    • 34248141778 scopus 로고    scopus 로고
    • Increased intestinal permeability in pathogenesis and progress of nonalcoholic steatohepatitis in rats
    • Jin X, Yu CH, Lv GC, Li YM. Increased intestinal permeability in pathogenesis and progress of nonalcoholic steatohepatitis in rats. World J Gastroenterol 2007;13:1732-6.
    • (2007) World J Gastroenterol , vol.13 , pp. 1732-1736
    • Jin, X.1    Yu, C.H.2    Lv, G.C.3    Li, Y.M.4
  • 42
    • 33847040759 scopus 로고    scopus 로고
    • Increased intestinal permeability in obese mice. new evidence in the pathogenesis of nonalcoholic steatohepatitis
    • Brun P, Castagliuolo I, Leo VD, Buda A, Pinzani M, Palu G, et al. Increased intestinal permeability in obese mice. new evidence in the pathogenesis of nonalcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol 2007;292:G518-25.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292 , pp. G518-G525
    • Brun, P.1    Castagliuolo, I.2    Leo, V.D.3    Buda, A.4    Pinzani, M.5    Palu, G.6
  • 43
    • 0020026596 scopus 로고
    • Effect of antibiotics in the prevention of jejunoileal bypass-induced liver dysfunction
    • Vanderhoof JA, Tuma DJ, Antonson DL, Sorrell MF. Effect of antibiotics in the prevention of jejunoileal bypass-induced liver dysfunction. Digestion 1982;23:9-15.
    • (1982) Digestion , vol.23 , pp. 9-15
    • Vanderhoof, J.A.1    Tuma, D.J.2    Antonson, D.L.3    Sorrell, M.F.4
  • 44
    • 0025964069 scopus 로고
    • Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline
    • Lichtman SN, Keku J, Schwab JH, Sartor RB. Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline. Gastroenterology 1991;100:513-9.
    • (1991) Gastroenterology , vol.100 , pp. 513-519
    • Lichtman, S.N.1    Keku, J.2    Schwab, J.H.3    Sartor, R.B.4
  • 45
    • 43049161319 scopus 로고    scopus 로고
    • Antibiotics protect against fructose-induced hepatic lipid accumulation in mice. role of endotoxin
    • Bergheim I, Weber S, Vos M, Krämer S, Volynets V, Kaserouni S, et al. Antibiotics protect against fructose-induced hepatic lipid accumulation in mice. role of endotoxin. J Hepatol 2008;48:983-92. http://dx.doi.org/10.1016/j.jhep.2008.01.035.
    • (2008) J Hepatol , vol.48 , pp. 983-992
    • Bergheim, I.1    Weber, S.2    Vos, M.3    Krämer, S.4    Volynets, V.5    Kaserouni, S.6
  • 46
    • 46749098265 scopus 로고    scopus 로고
    • Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice
    • Membrez M, Blancher F, Jaquet M, Bibiloni R, Cani PD, Burcelin RG, et al. Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice. Faseb J 2008;22:2416-26.
    • (2008) Faseb J , vol.22 , pp. 2416-2426
    • Membrez, M.1    Blancher, F.2    Jaquet, M.3    Bibiloni, R.4    Cani, P.D.5    Burcelin, R.G.6
  • 47
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Adachi Y, Moore LE, Bradford BU, Gao W, Thurman RG. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995;108:218-24.
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 49
    • 84884414277 scopus 로고    scopus 로고
    • Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice
    • Le Roy T, Llopis M, Lepage P, Bruneau A, Rabot S, Bevilacqua C, et al. Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice. Gut 2013;62:1787-94. http://dx.doi.org/10.1136/gutjnl-2012-303816.
    • (2013) Gut , vol.62 , pp. 1787-1794
    • Le Roy, T.1    Llopis, M.2    Lepage, P.3    Bruneau, A.4    Rabot, S.5    Bevilacqua, C.6
  • 50
    • 0025136962 scopus 로고
    • Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth
    • Lichtman SN, Sartor RB, Keku J, Schwab JH. Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth. Gastroenterology 1990;98:414-23.
    • (1990) Gastroenterology , vol.98 , pp. 414-423
    • Lichtman, S.N.1    Sartor, R.B.2    Keku, J.3    Schwab, J.H.4
  • 51
    • 84889264686 scopus 로고    scopus 로고
    • Analysis of breath volatile organic compounds as a noninvasive tool to diagnose nonalcoholic fatty liver disease in children
    • Alkhouri N, Cikach F, Eng K, Moses J, Patel N, Yan C, et al. Analysis of breath volatile organic compounds as a noninvasive tool to diagnose nonalcoholic fatty liver disease in children. Eur J Gastroenterol Hepatol 2014;26:82-7. http://dx.doi.org/10.1097/MEG.0b013-3283650669
    • (2014) Eur J Gastroenterol Hepatol , vol.26 , pp. 82-87
    • Alkhouri, N.1    Cikach, F.2    Eng, K.3    Moses, J.4    Patel, N.5    Yan, C.6
  • 52
    • 0034867956 scopus 로고    scopus 로고
    • Auto-brewery syndrome in a child with short gut syndrome: case report and review of the literature
    • Dahshan A, Donovan K. Auto-brewery syndrome in a child with short gut syndrome: case report and review of the literature. J Pediatr Gastroenterol Nutr 2001;33:214-5.
    • (2001) J Pediatr Gastroenterol Nutr , vol.33 , pp. 214-215
    • Dahshan, A.1    Donovan, K.2
  • 55
    • 0029935028 scopus 로고    scopus 로고
    • Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism
    • Klyosov AA, Rashkovetsky LG, Tahir MK, Keung WM. Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism. Biochemistry 1996;35:4445-56. http://dx.doi.org/10.1021/bi9521093.
    • (1996) Biochemistry , vol.35 , pp. 4445-4456
    • Klyosov, A.A.1    Rashkovetsky, L.G.2    Tahir, M.K.3    Keung, W.M.4
  • 56
    • 0033646582 scopus 로고    scopus 로고
    • Covalent adducts of proteins with acetaldehyde in the liver as a result of acetaldehyde administration in drinking water
    • Jokelainen K, Parkkila S, Salaspuro M, Niemelä O. Covalent adducts of proteins with acetaldehyde in the liver as a result of acetaldehyde administration in drinking water. J Hepatol 2000;33:926-32.
    • (2000) J Hepatol , vol.33 , pp. 926-932
    • Jokelainen, K.1    Parkkila, S.2    Salaspuro, M.3    Niemelä, O.4
  • 57
    • 0020536806 scopus 로고
    • Determinants of blood acetaldehyde level during ethanol oxidation in chronic alcoholics
    • Nuutinen H, Lindros KO, Salaspuro M. Determinants of blood acetaldehyde level during ethanol oxidation in chronic alcoholics. Alcohol Clin Exp Res 1983;7:163-8.
    • (1983) Alcohol Clin Exp Res , vol.7 , pp. 163-168
    • Nuutinen, H.1    Lindros, K.O.2    Salaspuro, M.3
  • 58
    • 0019911683 scopus 로고
    • Role of hepatic acetaldehyde dehydrogenase in alcoholism: demonstration of persistent reduction of cytosolic activity in abstaining patients
    • Thomas M, Halsall S, Peters TJ. Role of hepatic acetaldehyde dehydrogenase in alcoholism: demonstration of persistent reduction of cytosolic activity in abstaining patients. Lancet 1982;2:1057-8.
    • (1982) Lancet , vol.2 , pp. 1057-1058
    • Thomas, M.1    Halsall, S.2    Peters, T.J.3
  • 59
    • 0021942125 scopus 로고
    • Ethanol feeding can produce secondary alterations in aldehyde dehydrogenase isozymes
    • Alderman JA, Sanny C, Gordon E, Lieber CS. Ethanol feeding can produce secondary alterations in aldehyde dehydrogenase isozymes. Alcohol 1985;2:91-5.
    • (1985) Alcohol , vol.2 , pp. 91-95
    • Alderman, J.A.1    Sanny, C.2    Gordon, E.3    Lieber, C.S.4
  • 60
    • 17544373959 scopus 로고    scopus 로고
    • Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease
    • Rolla R, Vay D, Mottaran E, Parodi M, Traverso N, Aricó S, et al. Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease. Hepatology 2000;31:878-84. http://dx.doi.org/10.1053/he.2000.5373.S0270913900170168[pii].
    • (2000) Hepatology , vol.31 , pp. 878-884
    • Rolla, R.1    Vay, D.2    Mottaran, E.3    Parodi, M.4    Traverso, N.5    Aricó, S.6
  • 61
    • 84887583809 scopus 로고    scopus 로고
    • Plasma IgA antibody levels to malondialdehyde acetaldehyde-adducts are associated with inflammatory mediators, obesity and type 2 diabetes
    • Vehkala L, Ukkola O, Kesäniemi YA, Kähönen M, Nieminen MS, Salomaa V, et al. Plasma IgA antibody levels to malondialdehyde acetaldehyde-adducts are associated with inflammatory mediators, obesity and type 2 diabetes. Ann Med 2013;45:501-10. http://dx.doi.org/10.3109/07853890.2013.841322.
    • (2013) Ann Med , vol.45 , pp. 501-510
    • Vehkala, L.1    Ukkola, O.2    Kesäniemi, Y.A.3    Kähönen, M.4    Nieminen, M.S.5    Salomaa, V.6
  • 62
    • 20644453966 scopus 로고    scopus 로고
    • Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption
    • Viitala K, Israel Y, Blake JE, Niemela O. Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption. Hepatology 1997;25:1418-24.
    • (1997) Hepatology , vol.25 , pp. 1418-1424
    • Viitala, K.1    Israel, Y.2    Blake, J.E.3    Niemela, O.4
  • 64
    • 84891551821 scopus 로고    scopus 로고
    • Targeting aldehyde dehydrogenase 2: new therapeutic opportunities
    • Chen C-H, Ferreira JCB, Gross ER, Mochly-Rosen D. Targeting aldehyde dehydrogenase 2: new therapeutic opportunities. Physiol Rev 2014;94:1-34. http://dx.doi.org/10.1152/physrev.00017.2013.
    • (2014) Physiol Rev , vol.94 , pp. 1-34
    • Chen, C.-H.1    Ferreira, J.C.B.2    Gross, E.R.3    Mochly-Rosen, D.4
  • 65
    • 81055158018 scopus 로고    scopus 로고
    • Posttranslational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications
    • Song B-J, Abdelmegeed MA, Yoo S-H, Kim B-J, Jo SA, Jo I, et al. Posttranslational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications. J Proteomics 2011;74:2691-702. http://dx.doi.org/10.1016/j.jprot.2011.05.013.
    • (2011) J Proteomics , vol.74 , pp. 2691-2702
    • Song, B.-J.1    Abdelmegeed, M.A.2    Yoo, S.-H.3    Kim, B.-J.4    Jo, S.A.5    Jo, I.6
  • 66
    • 84925292438 scopus 로고    scopus 로고
    • Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking
    • Eriksson CJP. Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking. Adv Exp Med Biol 2015;815:41-58. http://dx.doi.org/10.1007/978-3-319-09614-8_3.
    • (2015) Adv Exp Med Biol , vol.815 , pp. 41-58
    • Eriksson, C.J.P.1
  • 67
    • 84869436442 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review
    • White DL, Kanwal F, El-Serag HB. Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review. Clin Gastroenterol Hepatol 2012;10(1342-59):e2. http://dx.doi.org/10.1016/j.cgh.2012.10.001.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 1342-1359
    • White, D.L.1    Kanwal, F.2    El-Serag, H.B.3
  • 68
    • 84916233134 scopus 로고    scopus 로고
    • The association between obesity and cancer risk: a meta-analysis of observational studies from 1985 to 2011
    • Dobbins M, Decorby K, Choi BCK. The association between obesity and cancer risk: a meta-analysis of observational studies from 1985 to 2011. ISRN Prev Med 2013;2013:680536. http://dx.doi.org/10.5402/2013/680536.
    • (2013) ISRN Prev Med , vol.2013
    • Dobbins, M.1    Decorby, K.2    Choi, B.C.K.3
  • 69
    • 84868110731 scopus 로고    scopus 로고
    • Metabolic syndrome and risk of cancer: a systematic review and meta-analysis
    • Esposito K, Chiodini P, Colao A, Lenzi A, Giugliano D. Metabolic syndrome and risk of cancer: a systematic review and meta-analysis. Diabetes Care 2012;35:2402-11. http://dx.doi.org/10.2337/dc12-0336.
    • (2012) Diabetes Care , vol.35 , pp. 2402-2411
    • Esposito, K.1    Chiodini, P.2    Colao, A.3    Lenzi, A.4    Giugliano, D.5
  • 70
    • 84857206311 scopus 로고    scopus 로고
    • Significantly increased risk of cancer in diabetes mellitus patients: a meta-analysis of epidemiological evidence in Asians and non-Asians
    • Noto H, Tsujimoto T, Noda M. Significantly increased risk of cancer in diabetes mellitus patients: a meta-analysis of epidemiological evidence in Asians and non-Asians. J Diabetes Investig 2012;3:24-33. http://dx.doi.org/10.1111/j.2040-1124.2011.00183.x.
    • (2012) J Diabetes Investig , vol.3 , pp. 24-33
    • Noto, H.1    Tsujimoto, T.2    Noda, M.3
  • 71
    • 84896693460 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea
    • Minville C, Hilleret M-N, Tamisier R, Aron-Wisnewsky J, Clement K, Trocme C, et al. Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea. Chest 2014;145:525-33. http://dx.doi.org/10.1378/chest.13-0938.
    • (2014) Chest , vol.145 , pp. 525-533
    • Minville, C.1    Hilleret, M.-N.2    Tamisier, R.3    Aron-Wisnewsky, J.4    Clement, K.5    Trocme, C.6
  • 72
    • 84885484560 scopus 로고    scopus 로고
    • Obstructive sleep apnea is associated with fatty liver and abnormal liver enzymes: a meta-analysis
    • Sookoian S, Pirola CJ. Obstructive sleep apnea is associated with fatty liver and abnormal liver enzymes: a meta-analysis. Obes Surg 2013;23:1815-25. http://dx.doi.org/10.1007/s11695-013-0981-4.
    • (2013) Obes Surg , vol.23 , pp. 1815-1825
    • Sookoian, S.1    Pirola, C.J.2
  • 74
    • 79957574861 scopus 로고    scopus 로고
    • Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde
    • Yang K, Feng C, Lip H, Bruce WR, O'Brien PJ. Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde. Chem Biol Interact 2011;191:315-21. http://dx.doi.org/10.1016/j.cbi.2011.02.027.
    • (2011) Chem Biol Interact , vol.191 , pp. 315-321
    • Yang, K.1    Feng, C.2    Lip, H.3    Bruce, W.R.4    O'Brien, P.J.5
  • 75
    • 33646086233 scopus 로고    scopus 로고
    • Glyoxal markedly compromises hepatocyte resistance to hydrogen peroxide
    • Shangari N, Chan TS, Popovic M, O'Brien PJ. Glyoxal markedly compromises hepatocyte resistance to hydrogen peroxide. Biochem Pharmacol 2006;71:1610-8.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1610-1618
    • Shangari, N.1    Chan, T.S.2    Popovic, M.3    O'Brien, P.J.4
  • 76
    • 0348049806 scopus 로고    scopus 로고
    • Toxicity of glyoxals-role of oxidative stress, metabolic detoxification and thiamine deficiency
    • Shangari N, Bruce WR, Poon R, O'Brien PJ. Toxicity of glyoxals-role of oxidative stress, metabolic detoxification and thiamine deficiency. Biochem Soc Trans 2003;31:1390-3.
    • (2003) Biochem Soc Trans , vol.31 , pp. 1390-1393
    • Shangari, N.1    Bruce, W.R.2    Poon, R.3    O'Brien, P.J.4
  • 77
    • 77955664397 scopus 로고    scopus 로고
    • Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH
    • Kimura Y, Hyogo H, Yamagishi S, Takeuchi M, Ishitobi T, Nabeshima Y, et al. Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH. J Gastroenterol 2010;45:750-7. http://dx.doi.org/10.1007/s00535-010-0203-y.
    • (2010) J Gastroenterol , vol.45 , pp. 750-757
    • Kimura, Y.1    Hyogo, H.2    Yamagishi, S.3    Takeuchi, M.4    Ishitobi, T.5    Nabeshima, Y.6
  • 78
    • 0035719180 scopus 로고    scopus 로고
    • Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3
    • MacDonald GA, Bridle KR, Ward PJ, Walker NI, Houglum K, George DK, et al. Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3. J Gastroenterol Hepatol 2001;16:599-606. jgh2445 [pii].
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 599-606
    • MacDonald, G.A.1    Bridle, K.R.2    Ward, P.J.3    Walker, N.I.4    Houglum, K.5    George, D.K.6
  • 79
    • 0242438087 scopus 로고    scopus 로고
    • Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis
    • George J, Pera N, Phung N, Leclercq I, Yun Hou J, Farrell G. Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis. J Hepatol 2003;39:756-64.
    • (2003) J Hepatol , vol.39 , pp. 756-764
    • George, J.1    Pera, N.2    Phung, N.3    Leclercq, I.4    Yun Hou, J.5    Farrell, G.6
  • 80
    • 21044437187 scopus 로고    scopus 로고
    • Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis
    • Albano E, Mottaran E, Vidali M, Reale E, Saksena S, Occhino G, et al. Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis. Gut 2005;54:987-93.
    • (2005) Gut , vol.54 , pp. 987-993
    • Albano, E.1    Mottaran, E.2    Vidali, M.3    Reale, E.4    Saksena, S.5    Occhino, G.6
  • 81
    • 38449120093 scopus 로고    scopus 로고
    • Lipopolysaccharide-binding protein plasma levels and liver TNF-alpha gene expression in obese patients: evidence for the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitis
    • Ruiz AG, Casafont F, Crespo J, Cayón A, Mayorga M, Estebanez A, et al. Lipopolysaccharide-binding protein plasma levels and liver TNF-alpha gene expression in obese patients: evidence for the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitis. Obes Surg 2007;17:1374-80. http://dx.doi.org/10.1007/s11695-007-9243-7.
    • (2007) Obes Surg , vol.17 , pp. 1374-1380
    • Ruiz, A.G.1    Casafont, F.2    Crespo, J.3    Cayón, A.4    Mayorga, M.5    Estebanez, A.6
  • 82
    • 79955531353 scopus 로고    scopus 로고
    • Diet, commensals and the intestine as sources of pathogenassociated molecular patterns in atherosclerosis, type 2 diabetes and nonalcoholic fatty liver disease
    • Erridge C. Diet, commensals and the intestine as sources of pathogenassociated molecular patterns in atherosclerosis, type 2 diabetes and nonalcoholic fatty liver disease. Atherosclerosis 2011;216:1-6. http://dx.doi.org/10.1016/j.atherosclerosis.2011.02.043.
    • (2011) Atherosclerosis , vol.216 , pp. 1-6
    • Erridge, C.1
  • 83
    • 33749070988 scopus 로고    scopus 로고
    • Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: role of nonoxidative metabolism
    • Wu H, Cai P, Clemens DL, Jerrells TR, Ansari GA, Kaphalia BS. Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: role of nonoxidative metabolism. Toxicol Appl Pharmacol 2006;216:238-47. http://dx.doi.org/10.1016/j.taap.2006.05.003.S0041-008X(06)00157-8[pii].
    • (2006) Toxicol Appl Pharmacol , vol.216 , pp. 238-247
    • Wu, H.1    Cai, P.2    Clemens, D.L.3    Jerrells, T.R.4    Ansari, G.A.5    Kaphalia, B.S.6
  • 84
    • 9644295685 scopus 로고    scopus 로고
    • Induction of apoptosis by fatty acid ethyl esters in HepG2 cells
    • Aydin HH, Celik HA, Deveci R, Karacali S, Saydam G, Bedii Omay S, et al. Induction of apoptosis by fatty acid ethyl esters in HepG2 cells. Food Chem Toxicol 2005;43:139-45. http://dx.doi.org/10.1016/j.fct.2004.09.003.S0278-6915(04)00285-6[pii].
    • (2005) Food Chem Toxicol , vol.43 , pp. 139-145
    • Aydin, H.H.1    Celik, H.A.2    Deveci, R.3    Karacali, S.4    Saydam, G.5    Bedii Omay, S.6
  • 85
    • 84857973671 scopus 로고    scopus 로고
    • Formation of hydroxymethyl DNA adducts in rats orally exposed to stable isotope labeled methanol
    • Lu K, Gul H, Upton PB, Moeller BC, Swenberg JAC. Formation of hydroxymethyl DNA adducts in rats orally exposed to stable isotope labeled methanol. Toxicol Sci 2012;126:28-38. http://dx.doi.org/10.1093/toxsci/kfr328.
    • (2012) Toxicol Sci , vol.126 , pp. 28-38
    • Lu, K.1    Gul, H.2    Upton, P.B.3    Moeller, B.C.4    Swenberg, J.A.C.5
  • 86
    • 79957556006 scopus 로고    scopus 로고
    • Metabolic mechanisms of methanol/formaldehyde in isolated rat hepatocytes: carbonyl-metabolizing enzymes versus oxidative stress
    • MacAllister SL, Choi J, Dedina L, O'Brien PJ. Metabolic mechanisms of methanol/formaldehyde in isolated rat hepatocytes: carbonyl-metabolizing enzymes versus oxidative stress. Chem Biol Interact 2011;191:308-14. http://dx.doi.org/10.1016/j.cbi.2011.01.017.
    • (2011) Chem Biol Interact , vol.191 , pp. 308-314
    • MacAllister, S.L.1    Choi, J.2    Dedina, L.3    O'Brien, P.J.4
  • 87
    • 84903523617 scopus 로고    scopus 로고
    • Dynamics of oxidative/nitrosative stress in mice with methionine-cholinedeficient diet-induced nonalcoholic fatty liver disease
    • Jorgacevic B, Mladenovic D, Ninkovic M, Prokic V, Stankovic M, Aleksic V, et al. Dynamics of oxidative/nitrosative stress in mice with methionine-cholinedeficient diet-induced nonalcoholic fatty liver disease. Hum Exp Toxicol 2013;33:701-9. http://dx.doi.org/10.1177/0960327113506723.
    • (2013) Hum Exp Toxicol , vol.33 , pp. 701-709
    • Jorgacevic, B.1    Mladenovic, D.2    Ninkovic, M.3    Prokic, V.4    Stankovic, M.5    Aleksic, V.6
  • 88
    • 34548804940 scopus 로고    scopus 로고
    • Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake
    • 86/3/661 [pii]
    • Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, et al. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake. Am J Clin Nutr 2007;86:661-71. doi:86/3/661 [pii].
    • (2007) Am J Clin Nutr , vol.86 , pp. 661-671
    • Musso, G.1    Gambino, R.2    De Michieli, F.3    Biroli, G.4    Premoli, A.5    Pagano, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.