Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde

Chemico-Biological Interactions

Volumn 191, Issue 1-3, 2011, Pages 315-321

  Yang, Kai ^a   Feng, Cynthia ^a   Lip, Hoyin ^a   Bruce, W R ^b   O'Brien, Peter J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Hydroxypyruvate; Glyceraldehyde; Glycolaldehyde; Hepatocyte cytotoxicity; Oxidative stress; Protein carbonylation

Indexed keywords

BETA HYDROXYPYRUVIC ACID; FRUCTOSE; GLUTATHIONE; GLYCERALDEHYDE; GLYCOALDEHYDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; AUTOOXIDATION; CELL ISOLATION; CELL PROTECTION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; ENZYME METABOLISM; LIVER CELL; MOLECULAR MECHANICS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEIN DEPLETION; RAT;

ACETALDEHYDE; ANIMALS; COPPER; FATTY LIVER; GLUTATHIONE; GLYCERALDEHYDE; GLYOXAL; HEPATOCYTES; HYDROGEN PEROXIDE; OXIDATION-REDUCTION; PROTEIN CARBONYLATION; PYRUVATES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 79957574861     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.02.027     Document Type: Conference Paper

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