Co-delivery of docetaxel and chloroquine via PEO-PPO-PCL/TPGS micelles for overcoming multidrug resistance

International Journal of Pharmaceutics

Volumn 495, Issue 2, 2015, Pages 932-939

  Shi, Chunhuan ^a   Zhang, Zhiqing ^b   Shi, Jiaxing ^a   Wang, Fang ^b   Luan, Yuxia ^a  

^a SHANDONG UNIVERSITY   (China)

^b CHINA UNIVERSITY OF PETROLEUM   (China)

Author keywords

Chloroquine; Docetaxel; Micelles; Multidrug resistance

Indexed keywords

CHLOROQUINE; COPOLYMER; DOCETAXEL; MACROGOL; NANOMATERIAL; POLY(PROPYLENE OXIDE); POLYCAPROLACTONE; PROPYLENE OXIDE; TOCOFERSOLAN; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ALPHA-TOCOPHERYL POLYETHYLENE GLYCOL SUCCINATE; ANTINEOPLASTIC AGENT; DRUG COMBINATION; MACROGOL DERIVATIVE; MICELLE; POLYESTER; POLYETHYLENE OXIDE-POLYCAPROLACTONE COPOLYMER; TAXOID;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG MIXTURE; DRUG POTENTIATION; DRUG UPTAKE; FLOW CYTOMETRY; HEMOLYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; IC50; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MCF 7 CELL LINE; MICELLE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; SYNTHESIS; ANALOGS AND DERIVATIVES; CELL DEATH; DRUG COMBINATION; DRUG EFFECTS; DRUG RELEASE; DRUG RESISTANCE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL DEATH; CELL LINE, TUMOR; CHLOROQUINE; DRUG COMBINATIONS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; HEMOLYSIS; HUMANS; MICELLES; POLYESTERS; POLYETHYLENE GLYCOLS; TAXOIDS; VITAMIN E;

EID: 84944111992     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.10.009     Document Type: Article

References (36)

1. A.K. Calgarotto, G.J. da Silva Pereira, A. Bechara, E.J. Paredes-Gamero, C.M. Barbosa, H. Hirata, and C. Bincoletto Autophagy inhibited Ehrlich ascitic tumor cells apoptosis induced by the nitrostyrene derivative compounds: relationship with cytosolic calcium mobilization Eur. J. Pharmacol. 678 2012 6 14
2. T.C. Chou Drug combination studies and their synergy quantification using the Chou-Talalay method Cancer Res. 70 2010 440 446
3. T.C. Chou, and P. Talaly A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems J. Biol. Chem. 252 1977 6438 6442
4. D.J. Crommelin, G. Storm, W. Jiskoot, R. Stenekes, E. Mastrobattista, and W.E. Hennink Nanotechnological approaches for the delivery of macromolecules J. Control. Release 87 2003 81 88
5. D. de Melo-Diogo, V.M. Gaspar, E.C. Costa, A.F. Moreira, D. Oppolzer, E. Gallardo, and I.J. Correia Combinatorial delivery of Crizotinib-Palbociclib-Sildenafil using TPGS-PLA micelles for improved cancer treatment Eur. J. Pharm. Biopharm. 88 3 2014 718 729
6. P.V. Desai, G.A. Sawada, I.A. Watson, and T.J. Raub Integration of in silico and in vitro tools for scaffold optimization during drug discovery: predicting P-glycoprotein efflux Mol. Pharm. 10 4 2013 1249 1261
7. M. El-Sayed, M.F. Kiani, M.D. Naimark, A.H. Hikal, and H. Ghandehari Extravasation of poly(amidoamine) (PAMAM) dendrimers across microvascular network endothelium Pharm. Res. 18 2001 23 28
8. P. Forsyth, G. Cairncross, D. Stewart, M. Goodyear, N. Wainman, and E. Eisenhauer Phase II trial of docetaxel in patients with recurrent malignant glioma: a study of the National Cancer Institute of Canada Clinical Trials Group Investig. New Drugs 14 2 1996 203 206
9. M.M. Gottesman, T. Fojo, and S.E. Bates Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. 2 2002 48 58
10. Y. Guo, M. Chu, S. Tan, S. Zhao, H. Liu, B.O. Otieno, and Z. Zhang Chitosan-g-TPGS nanoparticles for anticancer drug delivery and overcoming multidrug resistance Mol. Pharm. 11 2013 59 70
11. C.M.J. Hu, and L. Zhang Therapeutic nanoparticles to combat cancer drug resistance Curr. Drug Metab. 10 2009 836 841
12. C. Hu, V.R. Solomon, G. Ulibarri, and H. Lee The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine Bioorg. Med. Chem. 16 2008 7888 7893
13. C.M.J. Hu, S. Kaushal, H.S.T. Cao, S. Aryal, M. Sartor, S. Esener, and L. Zhang Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells Mol. Pharm. 7 2010 914 920
14. C.T. Keith, A.A. Borisy, and B.R. Stockwell Multicomponent therapeutics for networked systems Nat. Rev. Drug Discov. 4 2005 71 78
15. W.G. Kaelin The concept of synthetic lethality in the context of anticancer therapy Nat. Rev. Cancer 5 2005 689 698
16. Y. Li, K. Xiao, J. Luo, W. Xiao, J.S. Lee, A.M. Gonik, J. Kato, T.A. Dong, and K.S. Lam Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery Biomaterials 27 32 2011 6633 6645
17. M. Li, W. Song, Z. Tang, S. Lv, L. Lin, H. Sun, and X. Chen Nanoscaled poly(l-glutamic acid)/doxorubicin-amphiphile complex as pH-responsive drug delivery system for effective treatment of nonsmall cell lung cancer ACS Appl. Mater. Interfaces 5 2013 1781 1792
18. S.L. Lomonaco, S. Finniss, C. Xiang, A. DeCarvalho, F. Umansky, S.N. Kalkanis, T. Mikkelsen, and C. Brodie The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells Int. J. Cancer 125 3 2009 717 722
19. B.T. Luk, and L. Zhang Current advances in polymer-based nanotheranostics for cancer treatment and diagnosis ACS Appl. Mater. Interfaces 6 2014 21859 21873
20. H. Maeda, J. Fang, T. Inutsuka, and Y. Kitamoto Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications Int. J. Immunopharmacol. 3 2003 319 328
21. M.J. Manganiello, C. Cheng, A.J. Convertine, J.D. Bryers, and P.S. Stayton Diblock copolymers with tunable pH transitions for gene delivery Biomaterials 7 33 2012 2301 2309
22. P. Maycotte, S. Aryal, C.T. Cummings, J. Thorburn, M.J. Morgan, and A. Thorburn Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy Autophagy 8 2012 200 212
23. Y. Mo, H. Wang, J. Liu, Y. Lan, R. Guo, Y. Zhang, and Y. Zhang Controlled release and targeted delivery to cancer cells of doxorubicin from polysaccharide-functionalised single-walled carbon nanotubes J. Mater. Chem. B 3 2015 1846 1855
24. P. Pellegrini, A. Strambi, C. Zipoli, M. Hägg-Olofsson, M. Buoncervello, S. Linder, and A. De Milito Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies Autophagy 10 2014 562 571
25. K. Rajagopal, A. Mahmud, D.A. Christian, J.D. Pajerowski, A.E. Brown, S.M. Loverde, and D.E. Discher Curvature-coupled hydration of semicrystalline polymer amphiphiles yields flexible worm micelles but favors rigid vesicles: polycaprolactone-based block copolymers Macromolecules 43 2010 9736 9746
26. M. Sanson, M. Napolitano, R. Yaya, F. Keime-Guibert, P. Broët, K. Hoang-Xuan, and J.Y. Delattre Second line chemotherapy with docetaxel in patients with recurrent malignant glioma: a phase II study J. Neurooncol. 50 2000 245 249
27. J.R. Sharom, D.S. Bellows, and M. Tyers From large networks to small molecules Chem. Biol. 8 2004 81 90
28. C. Shi, Z. Zhang, F. Wang, X. Ji, Z. Zhao, and Y. Luan Docetaxel-loaded PEO-PPO-PCL/TPGS mixed micelles for overcoming multidrug resistance and enhancing antitumor efficacy J. Mater. Chem. B 3 2015 4259 4271
29. A. Singh, M. Talekar, T.H. Tran, A. Samanta, R. Sundaram, and M. Amiji Combinatorial approach in the design of multifunctional polymeric nano-delivery systems for cancer therapy J. Mater. Chem. B 2 2014 8069 8084
30. 6 does not induce P-glycoprotein-mediated multidrug resistance Biomaterials 21 21 2000 2203 2210
31. Y. Wang, Q. Luo, R. Sun, G. Zha, X. Li, Z. Shen, and W. Zhu Acid-triggered drug release from micelles based on amphiphilic oligo(ethylene glycol)-doxorubicin alternative copolymers J. Mater. Chem. B 2 2014 7612 7619
32. L. Xu, Z. Zhang, F. Wang, D. Xie, S. Yang, T. Wang, and C. Chu Synthesis, characterization, and self-assembly of linear poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ε-caprolactone) (PEO-PPO-PCL) copolymers J. Colloid Interface Sci. 393 2013 174 181
33. M. Xu, J. Qian, A. Suo, N. Cui, Y. Yao, W. Xu, and H. Wang Co-delivery of doxorubicin and P-glycoprotein siRNA by multifunctional triblock copolymers for enhanced anticancer efficacy in breast cancer cells J. Mater. Chem. B 3 2015 2215 2228
34. L. Zhang, F.X. Gu, J.M. Chan, A.Z. Wang, R.S. Langer, and O.C. Farokhzad Nanoparticles in medicine: therapeutic applications and developments Clin. Pharmacol. Ther. 83 2008 761 769
35. X. Zhang, X. Zeng, X. Liang, Y. Yang, X. Li, H. Chen, and S.S. Feng The chemotherapeutic potential of PEG-b-PLGA copolymer micelles that combine chloroquine as autophagy inhibitor and docetaxel as an anti-cancer drug Biomaterials 35 2014 9144 9154
36. W. Zhuang, B. Li, L. Long, L. Chen, Q. Huang, and Z. Liang Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity Int. J. Cancer 129 11 2011 2720 2731