Chitosan-g-TPGS nanoparticles for anticancer drug delivery and overcoming multidrug resistance

Molecular Pharmaceutics

Volumn 11, Issue 1, 2014, Pages 59-70

  Guo, Yuanyuan ^a   Chu, Min ^a   Tan, Songwei ^a   Zhao, Shuang ^a   Liu, Hanxiao ^a   Otieno, Ben Oketch ^a   Yang, Xiangliang ^a   Xu, Chuanrui ^a   Zhang, Zhiping ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

chitosan; doxorubicin; multidrug resistance; nanoparticles; TPGS

Indexed keywords

CHITOSAN GRAFT DEXTRO ALPHA TOCOPHERYL POLYETHYLENE GLYCOL; COPOLYMER; DOXORUBICIN; NANOPARTICLE; UNCLASSIFIED DRUG; VERAPAMIL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AREA UNDER THE CURVE; ARTICLE; BREAST ADENOCARCINOMA; CELL STRAIN MCF 7; CONFOCAL LASER SCANNING MICROSCOPE; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DOWN REGULATION; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG RELEASE; DRUG SYNTHESIS; ENCAPSULATION; EVAPORATION; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MAXIMUM PLASMA CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SOLVENT EXTRACTION; TIME TO MAXIMUM PLASMA CONCENTRATION; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CHITOSAN; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; FLOW CYTOMETRY; HUMANS; LIVER NEOPLASMS; MICE; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMERS; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED; VITAMIN E; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84891751669     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400514t     Document Type: Article

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