Analysis of Nearly One Thousand Mammalian Mirtrons Reveals Novel Features of Dicer Substrates

PLoS Computational Biology

Volumn 11, Issue 9, 2015, Pages

  Wen, Jiayu ^a   Ladewig, Erik ^a,c   Shenker, Sol ^a,b   Mohammed, Jaaved ^a,b   Lai, Eric C ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; MACHINERY; MAMMALS; RNA;

CHARACTERISTIC LENGTH; CHARACTERISTIC SEQUENCE; MAMMALIAN GENOMES; META-ANALYSIS; RNA DUPLEXES; SEQUENCE FEATURES; SEQUENCE LENGTHS; SMALL RNA; SPLICING MACHINERY; STRUCTURAL FEATURE;

SUBSTRATES;

DICER; MESSENGER RNA; MICRORNA; MICRORNA 1236; MICRORNA 4745; MICRORNA 5132; MICRORNA 6753; MIRTRON; UNCLASSIFIED DRUG; UNTRANSLATED RNA; RIBONUCLEASE III;

ARTICLE; BIOACCUMULATION; BIOGENESIS; CONTROLLED STUDY; DNA FLANKING REGION; DNA MODIFICATION; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; GENE EXPRESSION; GENE INTRON NUMBER; GENE LOCUS; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC PARAMETERS; GENETIC REGULATION; GENOMICS; HUMAN; INTRON; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; RNA PROCESSING; RNA SEQUENCE; RNA SPLICING; STRUCTURE ACTIVITY RELATION; URIDYLATION; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; CHEMISTRY; GENE LIBRARY; GENETICS; METABOLISM; PROCEDURES; SEQUENCE ANALYSIS;

ANIMALS; COMPUTATIONAL BIOLOGY; GENE LIBRARY; HUMANS; MICE; MICRORNAS; MODELS, GENETIC; RIBONUCLEASE III; SEQUENCE ANALYSIS, RNA;

EID: 84943574319     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004441     Document Type: Article

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