The master switchers in the aging of cardiovascular system, reverse senescence by microRNA signatures; as highly conserved molecules

Progress in Biophysics and Molecular Biology

Volumn 119, Issue 2, 2015, Pages 111-128

  Pourrajab, Fatemeh ^a   Vakili Zarch, Abbas ^a   Hekmatimoghaddam, Seyedhossein ^a   Zare Khormizi, Mohamad Reza ^a  

^a SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Aging; Cardiovascular system; microRNA

Indexed keywords

MICRORNA; SOMATOMEDIN C;

AGING; ANIMAL; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; CELL AGING; CELL DIFFERENTIATION; CELL LINEAGE; CYTOLOGY; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; GENOMIC INSTABILITY; HUMAN; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; PATHOLOGY; RAT; RISK FACTOR; SIGNAL TRANSDUCTION; STEM CELL;

AGING; ANIMALS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; CELL AGING; CELL DIFFERENTIATION; CELL LINEAGE; EPIGENESIS, GENETIC; FIBROSIS; GENE EXPRESSION REGULATION; GENOMIC INSTABILITY; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MICE; MICRORNAS; OXIDATION-REDUCTION; RATS; RISK FACTORS; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84943455508     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbiomolbio.2015.05.004     Document Type: Review

References (93)

1. Abonnenc M., et al. Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ. Res. 2013, 113(10):1138-1147.
2. van Almen G.C., et al. MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. Aging Cell. 2011, 10(5):76-79.
3. Bagnall R.D., et al. Global microRNA profiling of the mouse ventricles during development of severe hypertrophic cardiomyopathy and heart failure. PloS one 2012, 7(9):e44744.
4. Bai P., et al. PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell. Metab. 2011, 13(4):461-468.
5. Bisso A., et al. Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer. Cell. Cycle (Georgetown Tex. 1) 2013, 12(11):1679-1687.
6. Bisso A., et al. Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer. Cell. Cycle (Georgetown, Tex) 2013, 12(11):1679-1687.
7. Bonifacio L.N., Jarstfer M.B. MiRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts. PloS one 2010, 5(9).
8. Braunersreuther V., et al. Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury. J. Mol. Cell. Cardiol. 2013, 64:99-107.
9. Canto C., Auwerx J. Interference between PARPs and SIRT1: a novel approach to healthy ageing?. Aging 2011, 3(5):543-547.
10. Cha M.J., et al. MicroRNA-145 suppresses ROS-induced Ca2+ overload of cardiomyocytes by targeting CaMKIIdelta. Biochem. Biophys. Res. Commun. 2013, 435(4):720-726.
11. Chen P.S., et al. Dysregulation of microRNAs in cancer. J. Biomed. Sci. 2012, 19:90.
12. Chen K.C., et al. OxLDL causes both epigenetic modification and signaling regulation on the microRNA-29b gene: novel mechanisms for cardiovascular diseases. J. Mol. Cell. Cardiol. 2012, 52:587-595.
13. Chilton W.L., et al. Acute exercise leads to regulation of telomere-associated genes and microRNA expression in immune cells. PloS One 2014, 9(4):e92088.
14. Chimenti C., et al. Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure. Circ. Res. 2003, 93(7):604-613.
15. Csiszar A., et al. Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr. Vasc. Pharmacol. 2005, 3(3):285-291.
16. Das S., et al. Nuclear miRNA regulates the mitochondrial genome in the heart. Circ. Res. 8 2012, 110(12):1596-1603.
17. Devaux Y., et al. MicroRNA-150: a novel marker of left ventricular remodeling after acute myocardial infarction. Circ. Cardiovasc. Genet. 2013, 6(3):290-298.
18. Dong De-li, Yang Bao-feng Role of microRNAs in cardiac hypertrophy, myocardial fibrosis and heart failure. Acta Pharm. Sin. B 2011, 1(1):1-7.
19. Duisters R.F., et al. miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ. Res. 30 2009, 104(2):170-178. 6pp. following 8.
20. Duisters R.F., et al. miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ. Res. 2009, 104(2):170-178. 6p Following 8.
21. Dutta D., et al. Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities. Circ. Res. 2012, 110(8):1125-1138.
22. Gonzalez A., et al. Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan. Circ. Res. 2008, 102(5):597-606.
23. Gorospe M., Abdelmohsen K. MicroRegulators come of age in senescence. Trends Genet.: TIG 2011, 27(6):233-241.
24. Guo H., et al. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010, 466(7308):835-840.
25. Gurha P., et al. microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. PloS One 2013, 8(9):e75882.
26. Huang Z.P., et al. MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circ. Res. 2013, 112(9):1234-1243.
27. Ikeda S., et al. Altered microRNA expression in human heart disease. Physiol. Genomics 2007, 31(3):367-373.
28. Ito T., et al. MicroRNA-34a regulation of endothelial senescence. Biochem. Biophys. Res. Commun. 6 2010, 398(4):735-740.
29. Jayawardena T.M., et al. MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ. Res. 2012, 110(11):1465-1473.
30. Jazbutyte V., et al. MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart. Age Dordr. Neth. 2013, 35(3):747-762.
31. Khanna N., et al. MicroRNA-146b promotes myogenic differentiation and modulates multiple gene targets in muscle cells. PloS One 2014, 9(6):e100657.
32. Kim H.J., et al. Augmentation of NAD(+) by NQO1 attenuates cisplatin-mediated hearing impairment. Cell Death Dis. 2014, 5:e1292.
33. Konstantinidis K., et al. Mechanisms of cell death in heart disease. Arterioscler. Thromb. Vasc. Biol. 2012, 32(7):1552-1562.
34. Krishnan K., et al. MicroRNA-182-5p targets a network of genes involved in DNA repair. RNA (New York, NY) 2013, 19(2):230-242.
35. Lafferty-Whyte K., et al. Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms. Biochim. Biophys. Acta 2009, 1792(4):341-352.
36. Leung A.K., et al. Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm. Mol. Cell. 2011, 42(4):489-499.
37. Li G., et al. Alterations in microRNA expression in stress-induced cellular senescence. Mech. Ageing Dev. 2009, 130(11-12):731-741.
38. Li Y., et al. IGF-1 prevents oxidative stress induced-apoptosis in induced pluripotent stem cells which is mediated by microRNA-1. Biochem. Biophys. Res. Commun. 2012, 426(4):615-619.
39. Limana F., et al. Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation. Circ. Res. 2005, 97(8):e73-83.
40. Limana F., et al. HMGB1 attenuates cardiac remodelling in the failing heart via enhanced cardiac regeneration and miR-206-mediated inhibition of TIMP-3. PloS One 2011, 6(6):e19845.
41. Lopez-Otin C., et al. The hallmarks of aging. Cell 2013, 153(6):1194-1217.
42. Maes O.C., et al. Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts. J. Cell. Physiol. 2009, 221(1):109-119.
43. Magenta A., et al. miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition. Cell Death Differ. 2011, 18(10):1628-1639.
44. Magenta A., et al. Oxidative stress and microRNAs in vascular diseases. Int. J. Mol. Sci. 2013, 14(9):17319-17346.
45. Martinelli N.C., et al. An analysis of the global expression of microRNAs in an experimental model of physiological left ventricular hypertrophy. PloS One 2014, 9(4):e93271.
46. Matkovich S.J., et al. MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ. Res. 2010, 106(1):166-175.
47. Menghini R., et al. MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1. Circulation 2009, 120(15):1524-1532.
48. Menghini R., et al. MicroRNAs in endothelial senescence and atherosclerosis. J. Cardiovasc. Transl. Res. Dec 2013, 6(6):924-930.
49. Mohamed J.S., et al. MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1alpha network in skeletal muscle. Diabetes 2014, 63(5):1546-1559.
50. Moskwa P., et al. miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol. Cell 2011, 41(2):210-220.
51. Moskwa P., et al. miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol. Cell 2011, 41(2):210-220.
52. Motohashi N., et al. Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis. J. Cell Sci. 2013, 126(Pt 12):2678-2691.
53. Naga Prasad S.V., et al. Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J. Biol. Chem. 2009, 284(40):27487-27499.
54. Neijenhuis S., et al. Identification of miRNA modulators to PARP inhibitor response. DNA Repair 2013, 12(6):394-402.
55. Noren Hooten N., et al. microRNA expression patterns reveal differential expression of target genes with age. PloS One 2010, 5(5):e10724.
56. Pacher P., Szabo C. Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors. Cardiovasc. Drug Rev. 2007, 25(3):235-260.
57. Patrick D.M., et al. Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J. Clin. Investig. 2010, 120(11):3912-3916.
58. Porrello E.R., et al. MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes. Circ. Res. 2 2011, 109(6):670-679.
59. Potus F., et al. Vascular remodeling process in pulmonary arterial hypertension, with focus on miR-204 and miR-126 (2013 Grover Conference series). Pulm. Circ. 2014, 4(2):175-184.
60. Pourrajab F., et al. MicroRNA-based system in stem cell reprogramming; differentiation/dedifferentiation. Int. J. Biochem. Cell Biol. 2014, 20.
61. Pourrajab F., et al. Application of stem cell/growth factor system, as a multimodal therapy approach in regenerative medicine to improve cell therapy yields. Int. J. Cardiol. 15 2014, 173(1):12-19.
62. Qin B., et al. Role of microRNAs in endothelial inflammation and senescence. Mol. Biol. reports 2012, 39(4):4509-4518.
63. Rangrez A.Y., et al. miR-143 and miR-145: molecular keys to switch the phenotype of vascular smooth muscle cells. Circ. Cardiovasc. Genet. 2011, 4(2):197-205.
64. Rippe C., et al. MicroRNA changes in human arterial endothelial cells with senescence: relation to apoptosis, eNOS and inflammation. Exp. Gerontol. 2012, 47(1):45-51.
65. Rippo M.R., et al. MitomiRs in human inflamm-aging: a hypothesis involving miR-181a, miR-34a and miR-146a. Exp. Gerontol. 2014, 56:154-163.
66. van Rooij E., et al. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc. Natl. Acad. Sci. USA 2008, 105(35):13027-13032.
67. Rodier F., Campisi J. Four faces of cellular senescence. J. Cell Biol. 2011, 192(4):547-556.
68. Schraml E., Grillari J. From cellular senescence to age-associated diseases: the miRNA connection. Longev. Heal. 2012, 1(1):10.
69. Schroen B., Heymans S. Small but smart-microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing. Cardiovasc. Res. 2012, 93(4):605-613.
70. Seeger T., et al. Immunosenescence-associated microRNAs in age and heart failure. Eur. J. Heart Fail. 2013, 15(4):385-393.
71. Sharma A., et al. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J. Biol. Chem. 2013, 288(25):18439-18447.
72. Song X.W., et al. MicroRNAs are dynamically regulated in hypertrophic hearts, and miR-199a is essential for the maintenance of cell size in cardiomyocytes. J. Cell. Physiol. 2010, 225(2):437-443.
73. Staszel T., et al. Role of microRNAs in endothelial cell pathophysiology. Pol. Arch. Med. Wewnetrznej 2011, 121(10):361-366.
74. Tabuchi T., et al. MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression. Clin. Sci. Lond. Engl.: 1979) 2012, 123(3):161-171.
75. Takaya T., et al. MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells. Circ. J. Off. J. Jpn. Circ. Soc. 2009, 73(8):1492-1497.
76. Tan K.S., et al. Expression profile of MicroRNAs in young stroke patients. PloS One 2009, 4(11):e7689.
77. Tessitore A., et al. MicroRNAs in the DNA damage/repair network and cancer. Int. J. genomics 2014, 2014:820248.
78. Tian F.J., et al. Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis. Cardiovasc. Res. 2014, 103(1):100-110.
79. Topkara V.K., Mann D.L. Role of microRNAs in cardiac remodeling and heart failure. Cardiovasc. Drugs Therapy/Sponsor. Int. Soc. Cardiovasc. Pharmacother. 2011, 25(2):171-182.
80. Torella D., et al. Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression. Circ. Res. 2004, 94(4):514-524.
81. Tsirpanlis G. Cellular senescence, cardiovascular risk, and CKD: a review of established and hypothetical interconnections. Am. J. kidney Dis.: Off. J. Natl. Kidney Found. 2008, 51(1):131-144.
82. Ugalde A.P., et al. Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53. EMBO J. 2011, 30(11):2219-2232.
83. Varga Z.V., et al. MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart. J. Mol. Cell. Cardiol. 2013, 62:111-121.
84. Vasa-Nicotera M., et al. miR-146a is modulated in human endothelial cell with aging. Atherosclerosis 2011, 217(2):326-330.
85. Wang Y., et al. MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition. Cancer Res. 2012, 72(16):4037-4046.
86. Wang J., et al. MicroRNA-24 regulates cardiac fibrosis after myocardial infarction. J. Cell. Mol. Med. 2012, 16(9):2150-2160.
87. Wei Y., et al. MicroRNA-126, -145, and -155: a therapeutic triad in atherosclerosis?. Arteriosclerosis, Thromb. Vasc. Biol. 2013, 33(3):449-454.
88. Wu C.W., et al. MicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer. PloS One 2013, 8(2):e57036.
89. Yao E., Ventura A. A new role for miR-182 in DNA repair. Mol. Cell 2011, 41(2):135-137.
90. Zhang T., Kraus W.L. SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions. Biochimicaetbiophysicaacta 2010, 1804(8):1666-1675.
91. Zhang X., et al. The expression of microRNA and microRNA clusters in the aging heart. PloS One 2012, 7(4):e34688.
92. Zhao T., et al. MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1. Am. J. Physiol. Endocrinol. Metabol. 2010, 299(1):E110-E116.
93. Zhu H., et al. MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1. Cardiovasc. Res. 2011, 92(1):75-84.