Application of stem cell/growth factor system, as a multimodal therapy approach in regenerative medicine to improve cell therapy yields

International Journal of Cardiology

Volumn 173, Issue 1, 2014, Pages 12-19

  Pourrajab, Fatemeh ^a   Babaei Zarch, Mojtaba ^a   Baghi Yazdi, Mohammad ^a   Rahimi Zarchi, Abolfazl ^b   Vakili Zarch, Abbas ^a  

^a SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF SOCIAL WELFARE AND REHABILITATION SCIENCES   (Iran)

Author keywords

Growth factors; Regenerative medicine; Stem cell

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; CHEMOKINE; SIGNAL PEPTIDE;

ANGIOGENESIS; AUTOCRINE EFFECT; CELL FATE; CELL HOMING; CELL LINEAGE; CELL PROLIFERATION; CELL RENEWAL; CELL SURVIVAL; ENGRAFTMENT; ENZYME SYNTHESIS; GENE EXPRESSION; HEART CONTRACTION; HEART INFARCTION; HEART VENTRICLE WALL; HUMAN; PARACRINE SIGNALING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; REGENERATIVE MEDICINE; REVIEW; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION; TRANSCRIPTION INITIATION; ANIMAL; CELL DIFFERENTIATION; DRUG EFFECTS; HEART FAILURE; METABOLISM; MULTIMODALITY CANCER THERAPY; PHYSIOLOGY; PROCEDURES; SECRETION (PROCESS); STEM CELL; TRENDS;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMOKINES; COMBINED MODALITY THERAPY; HEART FAILURE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; REGENERATIVE MEDICINE; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 84897417014     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.02.006     Document Type: Review

References (81)

1. J.S. Da Silva, and J.M. Hare Cell-based therapies for myocardial repair: emerging role for bone marrow-derived mesenchymal stem cells (MSCs) in the treatment of the chronically injured heart Methods Mol Biol 1037 2013 145 163
2. J. Pons, Y. Huang, and J. Arakawa-Hoyt et al. VEGF improves survival of mesenchymal stem cells in infarcted hearts Biochem Biophys Res Commun 376 2 2008 419 422
3. J.M. Tang, J.N. Wang, and L. Zhang et al. VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart Cardiovasc Res 91 3 2011 402 411
4. D. Orlic, J. Kajstura, and S. Chimenti et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival Proc Natl Acad Sci U S A 98 8 2001 10344 10349
5. H. Haider, S. Jiang, N.M. Idris, and M. Ashraf IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair Circ Res 103 11 2008 1300 1308
6. J.F. Ji, B.P. He, S.T. Dheen, and S.S. Tay Interactions of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury Stem Cells 22 3 2004 415 427
7. A.L. Ponte, E. Marais, and N. Gallay et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities Stem Cells 25 7 2007 1737 1745
8. J. Fiedler, C. Brill, W.F. Blum, and R.E. Brenner IGF-I and IGF-II stimulate directed cell migration of bone marrow-derived human mesenchymal progenitor cells Biochem Biophys Res Commun 345 3 2006 1177 1183
9. J. Fiedler, G. Roderer, K.P. Gunther, and R.E. Brenner BMP-2, BMP-4, and PDGF-bb stimulate chemotactic migration of primary human mesenchymal progenitor cells J Cell Biochem 87 3 2002 305 312
10. A.T. Askari, S. Unzek, and Z.B. Popovic et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy Lancet 362 9385 2003 697 703
11. O. Kollet, S. Shivtiel, and Y.Q. Chen et al. HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34 + stem cell recruitment to the liver J Clin Invest 112 2 2003 160 169
12. D.E. Wright, A.J. Wagers, A.P. Gulati, F.L. Johnson, and I.L. Weissman Physiological migration of hematopoietic stem and progenitor cells Science 294 5548 2001 1933 1936
13. B. Witzenbichler, P.C. Maisonpierre, P. Jones, G.D. Yancopoulos, and J.M. Isner Chemotactic properties of angiopoietin-1 and - 2, ligands for the endothelial-specific receptor tyrosine kinase Tie2 J Biol Chem 273 29 1998 18514 18521
14. F. Arai, A. Hirao, and M. Ohmura et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche Cell 118 2 2004 149 161
15. K. Tamama, V.H. Fan, L.G. Griffith, H.C. Blair, and A. Wells Epidermal growth factor as a candidate for ex vivo expansion of bone marrow-derived mesenchymal stem cells Stem Cells 24 3 2006 686 695
16. R. Godiska, D. Chantry, and C.J. Raport et al. Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells J Exp Med 185 9 1997 1595 1604
17. N. Okumura, K. Tsuji, and Y. Ebihara et al. Chemotactic and chemokinetic activities of stem cell factor on murine hematopoietic progenitor cells Blood 87 10 1996 4100 4108
18. K. Urbanek, M. Rota, and S. Cascapera et al. Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival Circ Res 97 7 2005 663 673
19. T.M. Coyne, A.J. Marcus, D. Woodbury, and I.B. Black Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia Stem Cells 24 11 2006 2483 2492
20. M. Girgenrath, S. Weng, and C.A. Kostek et al. TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration EMBO J 25 24 2006 5826 5839
21. C. Ries, V. Egea, M. Karow, H. Kolb, M. Jochum, and P. Neth MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines Blood 109 9 2007 4055 4063
22. Y. Higashi, S. Sukhanov, A. Anwar, S.Y. Shai, and P. Delafontaine Aging, atherosclerosis, and IGF-1 J Gerontol A Biol Sci Med Sci 67 6 2012 626 639
23. P.G. Laustsen, S.J. Russell, and L. Cui et al. Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function Mol Cell Biol 27 5 2007 1649 1664
24. M. Grunewald, I. Avraham, and Y. Dor et al. VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells Cell 124 1 2006 175 189
25. T. Kofidis, J.L. de Bruin, and T. Yamane et al. Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration Stem Cells 22 7 2004 1239 1245
26. M.E. Davis, P.C. Hsieh, and T. Takahashi et al. Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction Proc Natl Acad Sci U S A 103 21 2006 8155 8160
27. T.M. Yau, C. Kim, G. Li, Y. Zhang, R.D. Weisel, and R.K. Li Maximizing ventricular function with multimodal cell-based gene therapy Circulation 112 9 Suppl. 2005 I123 I128
28. J. Ren, W.K. Samson, and J.R. Sowers Insulin-like growth factor I as a cardiac hormone: physiological and pathophysiological implications in heart disease J Mol Cell Cardiol 31 11 1999 2049 2061
29. R.L. Duerr, S. Huang, H.R. Miraliakbar, R. Clark, K.R. Chien, and J. Ross Jr. Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure J Clin Invest 95 2 1995 619 627
30. N. Abe, T. Matsunaga, and K. Kameda et al. Increased level of pericardial insulin-like growth factor-1 in patients with left ventricular dysfunction and advanced heart failure J Am Coll Cardiol 48 7 2006 1387 1395
31. Y.L. Tang, Q. Zhao, and Y.C. Zhang et al. Autologous mesenchymal stem cell transplantation induce VEGF and neovascularization in ischemic myocardium Regul Pept 117 1 2004 3 10
32. D. Torella, M. Rota, and D. Nurzynska et al. Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression Circ Res 94 4 2004 514 524
33. M. Gnecchi, H. He, and N. Noiseux et al. Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement FASEB J 20(6 2006 661 669
34. S. Mieno, B. Ramlawi, and M. Boodhwani et al. Role of stromal-derived factor-1alpha in the induction of circulating CD34 + CXCR4 + progenitor cells after cardiac surgery Circulation 114 1 Suppl. 2006 186 192
35. H.P. Gerber, V. Dixit, and N. Ferrara Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells J Biol Chem 273 21 1998 13313 13316
36. M. Clauss, M. Gerlach, and H. Gerlach et al. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration J Exp Med 172 6 1990 1535 1545
37. A.M. Byrne, D.J. Bouchier-Hayes, and J.H. Harmey Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF) J Cell Mol Med 9 4 2005 777 794
38. D.R. Senger, S.J. Galli, A.M. Dvorak, C.A. Perruzzi, V.S. Harvey, and H.F. Dvorak Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid Science 219 4587 1983 983 985
39. D. Zisa, A. Shabbir, G. Suzuki, and T. Lee Vascular endothelial growth factor (VEGF) as a key therapeutic trophic factor in bone marrow mesenchymal stem cell-mediated cardiac repair Biochem Biophys Res Commun 390 3 2009 834 838
40. S.G. Ball, C.A. Shuttleworth, and C.M. Kielty Vascular endothelial growth factor can signal through platelet-derived growth factor receptors J Cell Biol 177 3 2007 489 500
41. F. Pourrajab, S.K. Forouzannia, and S.A. Tabatabaee Molecular characteristics of bone marrow mesenchymal stem cells, source of regenerative medicine Int J Cardiol 163 2 2013 125 131
42. E. Potier, E. Ferreira, and R. Andriamanalijaona et al. Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression Bone 40 4 2007 1078 1087
43. B. Olofsson, K. Pajusola, and A. Kaipainen et al. Vascular endothelial growth factor B, a novel growth factor for endothelial cells Proc Natl Acad Sci U S A 93 6 1996 2576 2581
44. K. Matsudaira, K. Maeda, and N. Okumura et al. Impact of low levels of vascular endothelial growth factor after myocardial infarction on 6-month clinical outcome. Results from the Nagoya Acute Myocardial Infarction Study Circ J 76 6 2012 1509 1516
45. K.W. Lee, G.Y. Lip, and A.D. Blann Plasma angiopoietin-1, angiopoietin-2, angiopoietin receptor tie-2, and vascular endothelial growth factor levels in acute coronary syndromes Circulation 110 16 2004 2355 2360
46. A. Kranz, C. Rau, M. Kochs, and J. Waltenberger Elevation of vascular endothelial growth factor-A serum levels following acute myocardial infarction Evidence for its origin and functional significance J Mol Cell Cardiol 32 1 2000 65 72
47. P.R. Vale, D.W. Losordo, and C.E. Milliken et al. Left ventricular electromechanical mapping to assess efficacy of phVEGF(165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia Circulation 102 9 2000 965 974
48. D.W. Losordo, P.R. Vale, and R.C. Hendel et al. Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia Circulation 105 17 2002 2012 2018
49. J. Kastrup, E. Jorgensen, and S. Fuchs et al. A randomised, double-blind, placebo-controlled, multicentre study of the safety and efficacy of BIOBYPASS (AdGVVEGF121.10NH) gene therapy in patients with refractory advanced coronary artery disease: the NOVA trial EuroIntervention 6 7 2011 813 818
50. R.S. Ripa, Y. Wang, E. Jorgensen, H.E. Johnsen, B. Hesse, and J. Kastrup Intramyocardial injection of vascular endothelial growth factor-A165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease Eur Heart J 27 15 2006 1785 1792
51. M. Gyongyosi, A. Khorsand, and S. Zamini et al. NOGA-guided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study Circulation 112 9 Suppl. 2005 I157 I165
52. B. Assmus, V. Schachinger, and C. Teupe et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI) Circulation 106 24 2002 3009 3017
53. V. Schachinger, S. Erbs, and A. Elsasser et al. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction N Engl J Med 355 12 2006 1210 1221
54. R.G. Turan, T.I. Bozdag, and J. Ortak et al. Improved functional activity of bone marrow derived circulating progenitor cells after intra coronary freshly isolated bone marrow cells transplantation in patients with ischemic heart disease Stem Cell Rev 7 3 2011 646 656
55. A. Besse, F. Trimoreau, V. Praloran, and Y. Denizot Effect of cytokines and growth factors on the macrophage colony-stimulating factor secretion by human bone marrow stromal cells Cytokine 12 5 2000 522 525
56. T. Matsunaga, D.C. Warltier, J. Tessmer, D. Weihrauch, M. Simons, and W.M. Chilian Expression of VEGF and angiopoietins-1 and-2 during ischemia-induced coronary angiogenesis Am J Physiol Heart Circ Physiol 285 1 2003 H352 H358
57. K.E. Hatzistergos, H. Quevedo, and B.N. Oskouei et al. Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation Circ Res 107 7 2010 913 922
58. J.H. Qi, and L. Claesson-Welsh VEGF-induced activation of phosphoinositide 3-kinase is dependent on focal adhesion kinase Exp Cell Res 263 1 2001 173 182
59. H. Gille, J. Kowalski, and B. Li et al. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants J Biol Chem 276 5 2001 3222 3230
60. T.A. Brock, H.F. Dvorak, and D.R. Senger Tumor-secreted vascular permeability factor increases cytosolic Ca2 + and von Willebrand factor release in human endothelial cells Am J Pathol 138 1 1991 213 221
61. Y. Myoken, Y. Kayada, T. Okamoto, M. Kan, G.H. Sato, and J.D. Sato Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites Proc Natl Acad Sci U S A 88 13 1991 5819 5823
62. D.D. Ku, J.K. Zaleski, S. Liu, and T.A. Brock Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries Am J Physiol 265 2 Pt 2 1993 H586 H592
63. H.M. Wu, Q. Huang, Y. Yuan, and H.J. Granger VEGF induces NO-dependent hyperpermeability in coronary venules Am J Physiol 271 6 Pt 2 1996 H2735 H2739
64. L. Morbidelli, C.H. Chang, J.G. Douglas, H.J. Granger, F. Ledda, and M. Ziche Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium Am J Physiol 270 1 Pt 2 1996 H411 H415
65. M. Ziche, L. Morbidelli, E. Masini, H. Granger, P. Geppetti, and F. Ledda Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules Biochem Biophys Res Commun 192 3 1993 1198 1203
66. M. Ziche, L. Morbidelli, and E. Masini et al. Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P J Clin Invest 94(5 1994 2036 2044
67. S. Moncada, and A. Higgs The L-arginine-nitric oxide pathway N Engl J Med 329 27 1993 2002 2012
68. S.J. Leibovich, P.J. Polverini, T.W. Fong, L.A. Harlow, and A.E. Koch Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism Proc Natl Acad Sci U S A 91 10 1994 4190 4194
69. M. Ziche, L. Morbidelli, and R. Choudhuri et al. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis J Clin Invest 99 11 1997 2625 2634
70. M. Friedlander, P.C. Brooks, R.W. Shaffer, C.M. Kincaid, J.A. Varner, and D.A. Cheresh Definition of two angiogenic pathways by distinct alpha v integrins Science 270 5241 1995 1500 1502
71. Y. Asaumi, Y. Kagaya, and M. Takeda et al. Protective role of endogenous erythropoietin system in nonhematopoietic cells against pressure overload-induced left ventricular dysfunction in mice Circulation 115 15 2007 2022 2032
72. B.D. Westenbrink, E. Lipsic, and P. van der Meer et al. Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization Eur Heart J 28 16 2007 2018 2027
73. B.D. Westenbrink, H. Oeseburg, and L. Kleijn et al. Erythropoietin stimulates normal endothelial progenitor cell-mediated endothelial turnover, but attributes to neovascularization only in the presence of local ischemia Cardiovasc Drugs Ther 22 4 2008 265 274
74. B.D. Westenbrink, W.P. Ruifrok, and A.A. Voors et al. Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure Cardiovasc Res 87 1 2010 30 39
75. K. Reiss, W. Cheng, and P. Pierzchalski et al. Insulin-like growth factor-1 receptor and its ligand regulate the reentry of adult ventricular myocytes into the cell cycle Exp Cell Res 235 1 1997 198 209
76. S. Jiang, H. Haider, N.M. Idris, A. Salim, and M. Ashraf Supportive interaction between cell survival signaling and angiocompetent factors enhances donor cell survival and promotes angiomyogenesis for cardiac repair Circ Res 99 7 2006 776 784
77. T.B. Liu, P.W. Fedak, and R.D. Weisel et al. Enhanced IGF-1 expression improves smooth muscle cell engraftment after cell transplantation Am J Physiol Heart Circ Physiol 287 6 2004 H2840 H2849
78. N. Kanemitsu, K. Tambara, and G.U. Premaratne et al. Insulin-like growth factor-1 enhances the efficacy of myoblast transplantation with its multiple functions in the chronic myocardial infarction rat model J Heart Lung Transplant 25 10 2006 1253 1262
79. M. Parrizas, A.R. Saltiel, and D. LeRoith Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways J Biol Chem 272 1 1997 154 161
80. I. Elmadbouh, H. Haider, S. Jiang, N.M. Idris, G. Lu, and M. Ashraf Ex vivo delivered stromal cell-derived factor-1alpha promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium J Mol Cell Cardiol 42 4 2007 792 803
81. F.J. Giordano, H.P. Gerber, and S.P. Williams et al. A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function Proc Natl Acad Sci U S A 98 10 2001 5780 5785