MicroRNA-18a Attenuates DNA Damage Repair through Suppressing the Expression of Ataxia Telangiectasia Mutated in Colorectal Cancer

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Wu, Chung Wah ^a   Dong, Yu Juan ^a   Liang, Qiao Yi ^a   He, Xin Qi ^a,b   Ng, Simon S M ^a   Chan, Francis K L ^a   Sung, Joseph J Y ^a   Yu, Jun ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; MICRORNA; MICRORNA 18A; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; AGED; APOPTOSIS; ARTICLE; BINDING SITE; CANCER RECURRENCE; CANCER SURVIVAL; CELL VIABILITY; CLINICAL ARTICLE; COLON CARCINOGENESIS; COLONY FORMATION; COLORECTAL CANCER; COMET ASSAY; COMPUTER MODEL; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; ENZYME ASSAY; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; PROGRESSION FREE SURVIVAL; UPREGULATION; WESTERN BLOTTING;

EID: 84874300506     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057036     Document Type: Article

References (32)

1. Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
2. Guo H, Ingolia NT, Weissman JS, Bartel DP, (2010) Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466: 835-840.
3. Brennecke J, Cohen SM, (2003) Towards a complete description of the microRNA complement of animal genomes. Genome Biol 4: 228.
4. Chan JA, Krichevsky AM, Kosik KS, (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033.
5. Chen CZ, Calero M, DeRegis CJ, Heidtman M, Barlowe C, et al. (2004) Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor. Genetics 168: 1827-1841.
6. He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, et al. (2005) A microRNA polycistron as a potential human oncogene. Nature 435: 828-833.
7. Bandres E, Barricarte R, Cantero C, Honorato B, Malumbres R, et al. (2007) Epidermal growth factor receptor (EGFR) polymorphisms and survival in head and neck cancer patients. Oral Oncol 43: 713-719.
8. Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, et al. (2006) The colorectal microRNAome. Proc Natl Acad Sci U S A 103: 3687-3692.
9. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838.
10. Ng EK, Chong WW, Jin H, Lam EK, Shin VY, et al. (2009) Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 58: 1375-1381.
11. Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, et al. (2006) Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 38: 1060-1065.
12. Wang CL, Wang BB, Bartha G, Li L, Channa N, et al. (2006) Activation of an oncogenic microRNA cistron by provirus integration. Proc Natl Acad Sci U S A 103: 18680-18684.
13. Wu CW, Dong YJ, Ng SS, Leung WW, Lee CW, et al. (2011) Identification of a Panel of MicroRNAs in Stool as Screening Markers for Colorectal Cancer. Gastroenterology 140 (5Suppl 1): S-17.
14. Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, et al. (2005) A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 65: 9628-9632.
15. Diosdado B, van de Wiel MA, Terhaar Sive Droste JS, Mongera S, Postma C, et al. (2009) MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer 101: 707-714.
16. Song BJ, Matsunaga T, Hardwick JP, Park SS, Veech RL, et al. (1987) Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat. Mol Endocrinol 1: 542-547.
17. Tao J, Wu D, Li P, Xu B, Lu Q, et al. (2012) microRNA-18a, a member of the oncogenic miR-17-92 cluster, targets Dicer and suppresses cell proliferation in bladder cancer T24 cells. Molecular medicine reports 5: 167-172.
18. Morimura R, Komatsu S, Ichikawa D, Takeshita H, Tsujiura M, et al. (2011) Novel diagnostic value of circulating miR-18a in plasma of patients with pancreatic cancer. British journal of cancer 105: 1733-1740.
19. Kim WJ, Vo QN, Shrivastav M, Lataxes TA, Brown KD, (2002) Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line. Oncogene 21: 3864-3871.
20. Tamakawa RA, Fleisig HB, Wong JM, (2010) Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner. Cancer Res 70: 8684-8694.
21. Wu CW, Ng SS, Dong YJ, Ng SC, Leung WW, et al. (2012) Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps. Gut 61: 739-745.
22. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB, (2003) Prediction of mammalian microRNA targets. Cell 115: 787-798.
23. John B, Enright AJ, Aravin A, Tuschl T, Sander C, et al. (2004) Human MicroRNA targets. PLoS Biol 2: e363.
24. Bakkenist CJ, Kastan MB, (2003) DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506.
25. Derheimer FA, Kastan MB, (2010) Multiple roles of ATM in monitoring and maintaining DNA integrity. FEBS Lett 584: 3675-3681.
26. Boder E, Sedgwick RP, (1958) Ataxia-telangiectasia; a familial syndrome of progressive cerebellar ataxia, oculocutaneous telangiectasia and frequent pulmonary infection. Pediatrics 21: 526-554.
27. Kastan MB, Lim DS, Kim ST, Xu B, Canman C, (2000) Multiple signaling pathways involving ATM. Cold Spring Harb Symp Quant Biol 65: 521-526.
28. Lavin MF, Shiloh Y, (1997) The genetic defect in ataxia-telangiectasia. Annu Rev Immunol 15: 177-202.
29. Roossink F, Wieringa HW, Noordhuis MG, et al. (2012) The role of ATM and 53BP1 as predictive markers in cervical cancer. International journal of cancer. Journal international du cancer 131: 2056-66.
30. Jiang H, Reinhardt HC, Bartkova J, Tommiska J, Blomqvist C, et al. (2009) The combined status of ATM and p53 link tumor development with therapeutic response. Genes & development 23: 1895-909.
31. Huehls AM, Wagner JM, Huntoon CJ, Geng L, Erlichman C, et al. (2011) Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells. Cancer research 71: 4944-54.
32. Adamsen BL, Kravik KL, De Angelis PM, (2011) DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status. International journal of oncology 39: 673-82.