-
1
-
-
84872225149
-
PGC1alpha and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders
-
Austin S, St-Pierre J. PGC1alpha and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders. J Cell Sci. 2012; 125:4963-4971.
-
(2012)
J Cell Sci.
, vol.125
, pp. 4963-4971
-
-
Austin, S.1
St-Pierre, J.2
-
2
-
-
79251539237
-
The importance of PGC-1alpha in contractile activity-induced mitochondrial adaptations
-
Uguccioni G, Hood DA. The importance of PGC-1alpha in contractile activity-induced mitochondrial adaptations. Am J Physiol Endocrinol Metab. 2011; 300:E361-71.
-
(2011)
Am J Physiol Endocrinol Metab.
, vol.300
, pp. E361-E371
-
-
Uguccioni, G.1
Hood, D.A.2
-
3
-
-
58149326913
-
Activation of mitochondrial biogenesis by hormesis
-
Sano M, Fukuda K. Activation of mitochondrial biogenesis by hormesis. Circ Res. 2008; 103:1191-1193.
-
(2008)
Circ Res.
, vol.103
, pp. 1191-1193
-
-
Sano, M.1
Fukuda, K.2
-
4
-
-
0037389416
-
Raising Ca2+ in L6 myotubes mimics effects of exercise on mitochondrial biogenesis in muscle
-
Ojuka EO, Jones TE, Han DH, Chen M, Holloszy JO. Raising Ca2+ in L6 myotubes mimics effects of exercise on mitochondrial biogenesis in muscle. FASEB J. 2003; 17:675-681.
-
(2003)
FASEB J.
, vol.17
, pp. 675-681
-
-
Ojuka, E.O.1
Jones, T.E.2
Han, D.H.3
Chen, M.4
Holloszy, J.O.5
-
5
-
-
71849083948
-
Abnormal mitochondrial dynamics and neurodegenerative diseases
-
Su B, Wang X, Zheng L, Perry G, Smith MA, Zhu X. Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease. 2010; 1802:135-142.
-
(2010)
Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease.
, vol.1802
, pp. 135-142
-
-
Su, B.1
Wang, X.2
Zheng, L.3
Perry, G.4
Smith, M.A.5
Zhu, X.6
-
6
-
-
79551600416
-
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
-
Iwasawa R, Mahul-Mellier A, Datler C, Pazarentzos E, Grimm S. Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J. 2011; 30:556-568.
-
(2011)
EMBO J.
, vol.30
, pp. 556-568
-
-
Iwasawa, R.1
Mahul-Mellier, A.2
Datler, C.3
Pazarentzos, E.4
Grimm, S.5
-
7
-
-
84877813802
-
A comparative study of protein carbonylation and mitochondrial dysfunction using the neurotoxicants 1, 3-dinitrobenzene, 3-nitropropionic acid, and 3-chloropropanediol
-
Steiner SR, Milton E, Philbert MA. A comparative study of protein carbonylation and mitochondrial dysfunction using the neurotoxicants 1, 3-dinitrobenzene, 3-nitropropionic acid, and 3-chloropropanediol. Neurotoxicology. 2013; 37:74-84.
-
(2013)
Neurotoxicology.
, vol.37
, pp. 74-84
-
-
Steiner, S.R.1
Milton, E.2
Philbert, M.A.3
-
8
-
-
84874435362
-
The energy cost of action potential propagation in dopamine neurons: Clues to susceptibility in parkinson's disease
-
Pissadaki EK, Bolam JP. The energy cost of action potential propagation in dopamine neurons: Clues to susceptibility in parkinson's disease. Frontiers in Computational Neuroscience. 2013; 7.
-
(2013)
Frontiers in Computational Neuroscience
, pp. 7
-
-
Pissadaki, E.K.1
Bolam, J.P.2
-
11
-
-
84900434854
-
Axon degeneration and PGC1a-mediated protection in a vertebrate model of a-synuclein toxicity
-
O'Donnell KC, Lulla A, Stahl MC, Wheat ND, Bronstein JM, Sagasti A. Axon degeneration and PGC1a-mediated protection in a vertebrate model of a-synuclein toxicity. Disease Models & Mechanisms. 2014.
-
(2014)
Disease Models & Mechanisms
-
-
O'Donnell, K.C.1
Lulla, A.2
Stahl, M.C.3
Wheat, N.D.4
Bronstein, J.M.5
Sagasti, A.6
-
12
-
-
77957742105
-
Mitochondrial loss, dysfunction and altered dynamics in huntington's disease
-
Kim J, Moody JP, Edgerly CK, Bordiuk OL, Cormier K, Smith K, Beal MF, Ferrante RJ. Mitochondrial loss, dysfunction and altered dynamics in huntington's disease. Hum Mol Genet. 2010; 19:3919-3935.
-
(2010)
Hum Mol Genet.
, vol.19
, pp. 3919-3935
-
-
Kim, J.1
Moody, J.P.2
Edgerly, C.K.3
Bordiuk, O.L.4
Cormier, K.5
Smith, K.6
Beal, M.F.7
Ferrante, R.J.8
-
13
-
-
33745429701
-
Past adult lead exposure is linked to neurodegeneration measured by brain MRI
-
Stewart WF, Schwartz BS, Davatzikos C, Shen D, Liu D, Wu X, Todd AC, Shi W, Bassett S, Youssem D. Past adult lead exposure is linked to neurodegeneration measured by brain MRI. Neurology. 2006; 66:1476-1484.
-
(2006)
Neurology.
, vol.66
, pp. 1476-1484
-
-
Stewart, W.F.1
Schwartz, B.S.2
Davatzikos, C.3
Shen, D.4
Liu, D.5
Wu, X.6
Todd, A.C.7
Shi, W.8
Bassett, S.9
Youssem, D.10
-
14
-
-
33845298245
-
Whole-body lifetime occupational lead exposure and risk of parkinson's disease
-
Coon S, Stark A, Peterson E, Gloi A, Kortsha G, Pounds J, Chettle D, Gorell J. Whole-body lifetime occupational lead exposure and risk of parkinson's disease. Environ Health Perspect. 2006:1872-1876.
-
(2006)
Environ Health Perspect
, pp. 1872-1876
-
-
Coon, S.1
Stark, A.2
Peterson, E.3
Gloi, A.4
Kortsha, G.5
Pounds, J.6
Chettle, D.7
Gorell, J.8
-
15
-
-
84943428054
-
Association of cumulative lead exposure with parkinson's disease
-
Weisskopf MG, Weuve J, Nie H, Saint-Hilaire M, Sudarsky L, Simon DK, Hersh B, Schwartz J, Wright RO, Hu H. Association of cumulative lead exposure with parkinson's disease. 2010.
-
(2010)
-
-
Weisskopf, M.G.1
Weuve, J.2
Nie, H.3
Saint-Hilaire, M.4
Sudarsky, L.5
Simon, D.K.6
Hersh, B.7
Schwartz, J.8
Wright, R.O.9
Hu, H.10
-
16
-
-
1642493782
-
Correlation between clinical indicators of lead poisoning and oxidative stress parameters in controls and lead-exposed workers
-
Gurer-Orhan H, Sabir HU, Özgünes H. Correlation between clinical indicators of lead poisoning and oxidative stress parameters in controls and lead-exposed workers. Toxicology. 2004; 195:147-154.
-
(2004)
Toxicology.
, vol.195
, pp. 147-154
-
-
Gurer-Orhan, H.1
Sabir, H.U.2
Özgünes, H.3
-
17
-
-
58149147335
-
Lead-induced oxidative stress adversely affects health of the occupational workers
-
Khan DA, Qayyum S, Saleem S, Khan FA. Lead-induced oxidative stress adversely affects health of the occupational workers. Toxicol Ind Health. 2008; 24:611-618.
-
(2008)
Toxicol Ind Health.
, vol.24
, pp. 611-618
-
-
Khan, D.A.1
Qayyum, S.2
Saleem, S.3
Khan, F.A.4
-
18
-
-
85027937309
-
Lead-induced ER calcium release and inhibitory effects of methionine choline in cultured rat hippocampal neurons
-
Fan G, Zhou F, Feng C, Wu F, Ye W, Wang C, Lin F, Yan J, Li Y, Chen Y. Lead-induced ER calcium release and inhibitory effects of methionine choline in cultured rat hippocampal neurons. Toxicology in Vitro. 2013; 27:387-395.
-
(2013)
Toxicology in Vitro.
, vol.27
, pp. 387-395
-
-
Fan, G.1
Zhou, F.2
Feng, C.3
Wu, F.4
Ye, W.5
Wang, C.6
Lin, F.7
Yan, J.8
Li, Y.9
Chen, Y.10
-
19
-
-
4544355935
-
Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle
-
Schaeffer PJ, Wende AR, Magee CJ, Neilson JR, Leone TC, Chen F, Kelly DP. Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle. J Biol Chem. 2004; 279:39593-39603.
-
(2004)
J Biol Chem.
, vol.279
, pp. 39593-39603
-
-
Schaeffer, P.J.1
Wende, A.R.2
Magee, C.J.3
Neilson, J.R.4
Leone, T.C.5
Chen, F.6
Kelly, D.P.7
-
20
-
-
0037417334
-
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
-
Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC. Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol. 2003; 160:1115-1127.
-
(2003)
J Cell Biol.
, vol.160
, pp. 1115-1127
-
-
Breckenridge, D.G.1
Stojanovic, M.2
Marcellus, R.C.3
Shore, G.C.4
-
21
-
-
65649092131
-
Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: Spare respiratory capacity and stochastic mitochondrial failure
-
Choi SW, Gerencser AA, Nicholls DG. Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: Spare respiratory capacity and stochastic mitochondrial failure. J Neurochem. 2009; 109:1179-1191.
-
(2009)
J Neurochem.
, vol.109
, pp. 1179-1191
-
-
Choi, S.W.1
Gerencser, A.A.2
Nicholls, D.G.3
-
22
-
-
34447122557
-
Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone
-
Yadava N, Nicholls DG. Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. J Neurosci. 2007; 27:7310-7317.
-
(2007)
J Neurosci.
, vol.27
, pp. 7310-7317
-
-
Yadava, N.1
Nicholls, D.G.2
-
23
-
-
79959634508
-
PPAR? co-activator-1a (PGC-1a) reduces amyloid-ß generation through a PPAR?-dependent mechanism
-
Katsouri L, Parr C, Bogdanovic N, Willem M, Sastre M. PPAR? co-activator-1a (PGC-1a) reduces amyloid-ß generation through a PPAR?-dependent mechanism. J Alzheimer's Dis. 2011; 25:151-162.
-
(2011)
J Alzheimer's Dis.
, vol.25
, pp. 151-162
-
-
Katsouri, L.1
Parr, C.2
Bogdanovic, N.3
Willem, M.4
Sastre, M.5
-
24
-
-
84900434854
-
Axon degeneration and PGC-1alpha-mediated protection in a zebrafish model of alpha-synuclein toxicity
-
O'Donnell KC, Lulla A, Stahl MC, Wheat ND, Bronstein JM, Sagasti A. Axon degeneration and PGC-1alpha-mediated protection in a zebrafish model of alpha-synuclein toxicity. Dis Model Mech. 2014; 7:571-582.
-
(2014)
Dis Model Mech.
, vol.7
, pp. 571-582
-
-
O'Donnell, K.C.1
Lulla, A.2
Stahl, M.C.3
Wheat, N.D.4
Bronstein, J.M.5
Sagasti, A.6
-
25
-
-
38449092832
-
Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators
-
Spiegelman BM. Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators. 2007; 287:60.
-
(2007)
, vol.287
, pp. 60
-
-
Spiegelman, B.M.1
-
26
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jäger S, Handschin C, Zheng K, Lin J, Yang W. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell. 2006; 127:397-408.
-
(2006)
Cell.
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jäger, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
-
27
-
-
31844439407
-
Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients:"Mitohormesis" for health and vitality
-
Tapia PC. Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients:"Mitohormesis" for health and vitality. Med Hypotheses. 2006; 66:832-843.
-
(2006)
Med Hypotheses.
, vol.66
, pp. 832-843
-
-
Tapia, P.C.1
-
28
-
-
84859242538
-
Sustained expression of PGC-1alpha in the rat nigrostriatal system selectively impairs dopaminergic function
-
Ciron C, Lengacher S, Dusonchet J, Aebischer P, Schneider BL. Sustained expression of PGC-1alpha in the rat nigrostriatal system selectively impairs dopaminergic function. Hum Mol Genet. 2012; 21:1861-1876.
-
(2012)
Hum Mol Genet.
, vol.21
, pp. 1861-1876
-
-
Ciron, C.1
Lengacher, S.2
Dusonchet, J.3
Aebischer, P.4
Schneider, B.L.5
-
29
-
-
23844494686
-
Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise
-
Cartoni R, Leger B, Hock MB, Praz M, Crettenand A, Pich S, Ziltener JL, Luthi F, Deriaz O, Zorzano A, Gobelet C, Kralli A, Russell AP. Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise. J Physiol. 2005; 567:349-358.
-
(2005)
J Physiol.
, vol.567
, pp. 349-358
-
-
Cartoni, R.1
Leger, B.2
Hock, M.B.3
Praz, M.4
Crettenand, A.5
Pich, S.6
Ziltener, J.L.7
Luthi, F.8
Deriaz, O.9
Zorzano, A.10
Gobelet, C.11
Kralli, A.12
Russell, A.P.13
-
30
-
-
84894425052
-
A role for peroxisome proliferator-activated receptor gamma coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth
-
Martin OJ, Lai L, Soundarapandian MM, Leone TC, Zorzano A, Keller MP, Attie AD, Muoio DM, Kelly DP. A role for peroxisome proliferator-activated receptor gamma coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth. Circ Res. 2014; 114:626-636.
-
(2014)
Circ Res.
, vol.114
, pp. 626-636
-
-
Martin, O.J.1
Lai, L.2
Soundarapandian, M.M.3
Leone, T.C.4
Zorzano, A.5
Keller, M.P.6
Attie, A.D.7
Muoio, D.M.8
Kelly, D.P.9
-
31
-
-
0032936755
-
Etiology and pathogenesis of parkinson's disease
-
Olanow C, Tatton W. Etiology and pathogenesis of parkinson's disease. Annu Rev Neurosci. 1999; 22:123-144.
-
(1999)
Annu Rev Neurosci.
, vol.22
, pp. 123-144
-
-
Olanow, C.1
Tatton, W.2
-
32
-
-
79955487757
-
Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1
-
Merrill RA, Dagda RK, Dickey AS, Cribbs JT, Green SH, Usachev YM, Strack S. Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. PLoS Biology. 2011; 9:e1000612.
-
(2011)
PLoS Biology.
, vol.9
-
-
Merrill, R.A.1
Dagda, R.K.2
Dickey, A.S.3
Cribbs, J.T.4
Green, S.H.5
Usachev, Y.M.6
Strack, S.7
-
33
-
-
10744222588
-
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK
-
1
-
Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J, Jäeger S, Erdjument-Bromage H, Tempst P, Spiegelman BM. Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes Dev. 2004; 1;18(3):278-89.
-
(2004)
Genes Dev
, vol.18
, Issue.3
, pp. 278-289
-
-
Fan, M.1
Rhee, J.2
St-Pierre, J.3
Handschin, C.4
Puigserver, P.5
Lin, J.6
Jäeger, S.7
Erdjument-Bromage, H.8
Tempst, P.9
Spiegelman, B.M.10
-
34
-
-
33644762875
-
Cellular mechanisms of lead neurotoxicity
-
Garza A, Vega R, Soto E. Cellular mechanisms of lead neurotoxicity. Med Sci Monit. 2006; 12:RA57-65.
-
(2006)
Med Sci Monit
, vol.12
, pp. RA57-RA65
-
-
Garza, A.1
Vega, R.2
Soto, E.3
-
35
-
-
0034618728
-
Stimulatory and inhibitory effects of inorganic lead on calcineurin
-
Kern M, Audesirk G. Stimulatory and inhibitory effects of inorganic lead on calcineurin. Toxicology. 2000; 150:171-178.
-
(2000)
Toxicology.
, vol.150
, pp. 171-178
-
-
Kern, M.1
Audesirk, G.2
-
36
-
-
27844472724
-
Disruption of endoplasmic reticulum calcium stores is involved in neuronal death induced by glycolysis inhibition in cultured hippocampal neurons
-
Hernández-Fonseca K, Massieu L. Disruption of endoplasmic reticulum calcium stores is involved in neuronal death induced by glycolysis inhibition in cultured hippocampal neurons. J Neurosci Res. 2005; 82:196-205.
-
(2005)
J Neurosci Res.
, vol.82
, pp. 196-205
-
-
Hernández-Fonseca, K.1
Massieu, L.2
-
37
-
-
3242675057
-
Association of active caspase 8 with the mitochondrial membrane during apoptosis: Potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death
-
Chandra D, Choy G, Deng X, Bhatia B, Daniel P, Tang DG. Association of active caspase 8 with the mitochondrial membrane during apoptosis: Potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. Mol Cell Biol. 2004; 24:6592-6607.
-
(2004)
Mol Cell Biol.
, vol.24
, pp. 6592-6607
-
-
Chandra, D.1
Choy, G.2
Deng, X.3
Bhatia, B.4
Daniel, P.5
Tang, D.G.6
-
38
-
-
0037417334
-
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
-
Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC. Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol. 2003; 160:1115-1127.
-
(2003)
J Cell Biol.
, vol.160
, pp. 1115-1127
-
-
Breckenridge, D.G.1
Stojanovic, M.2
Marcellus, R.C.3
Shore, G.C.4
-
39
-
-
0023760665
-
The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
-
Gundersen H, Bagger P, Bendtsen T, Evans S, Korbo L, Marcussen N, Møller A, Nielsen K, Nyengaard J, Pakkenberg B. The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS. 1988; 96:857-881.
-
(1988)
APMIS.
, vol.96
, pp. 857-881
-
-
Gundersen, H.1
Bagger, P.2
Bendtsen, T.3
Evans, S.4
Korbo, L.5
Marcussen, N.6
Møller, A.7
Nielsen, K.8
Nyengaard, J.9
Pakkenberg, B.10
-
40
-
-
33847661809
-
Protocol for the fast chromatin immunoprecipitation (ChIP) method
-
Nelson JD, Denisenko O, Bomsztyk K. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nature Protocols. 2006; 1:179-185.
-
(2006)
Nature Protocols.
, vol.1
, pp. 179-185
-
-
Nelson, J.D.1
Denisenko, O.2
Bomsztyk, K.3
|