Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise

Journal of Physiology

Volumn 567, Issue 1, 2005, Pages 349-358

  Cartoni, Romain ^a   Léger, Bertrand ^a   Hock, M Benjamin ^b   Praz, Manu ^a   Crettenand, Antoinette ^a   Pich, Sara ^c   Ziltener, Jean Luc ^a   Luthi, François ^a   Dériaz, Olivier ^a   Zorzano, Antonio ^c   Gobelet, Charles ^a   Kralli, Anastasia ^b   Russell, Aaron P ^a  

^a SUVA   (Switzerland)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; MITOFUSIN 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; CYCLOOXYGENASE 4; GA BINDING PROTEIN; NUCLEAR RESPIRATORY FACTOR 1; PROSTAGLANDIN SYNTHASE;

ADULT; ARTICLE; CELL FUSION; CONTROLLED STUDY; EXERCISE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IN VITRO STUDY; MALE; MITOCHONDRION; NORMAL HUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SKELETAL MUSCLE; AEROBIC EXERCISE; GENE EXPRESSION; TRANSCRIPTION REGULATION;

ADULT; ENERGY METABOLISM; ESTROGEN RECEPTOR ALPHA; EXERCISE; GENE EXPRESSION; GTP PHOSPHOHYDROLASES; HUMANS; MALE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION;

EID: 23844494686     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2005.092031     Document Type: Article

References (35)

1. Baar K, Wende AR, Jones TE, Marison M, Nolte LA, Chen M, Kelly DP & Holloszy JO (2002). Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J 16, 1879-1886.
2. Bach D, Pich S, Soriano FX, Vega N, Baumgartner B, Oriola J, Daugaard JR, Lloberas J, Camps M, Zierath JR, Rabasa-Lhoret R, Wallberg-Henriksson H, Laville M, Palacin M, Vidal H, Rivera F, Brand M & Zorzano A (2003). Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem 278, 17190-17197.
3. Chen H, Lin RJ, Xie W, Wilpitz D & Evans RM (1999). Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell 98, 675-686.
4. Dela F, Mikines KJ, von Linstow M, Secher NH & Galbo H (1992). Effect of training on insulin-mediated glucose uptake in human muscle. Am J Physiol 263, E1134-E1143.
5. Dempster P & Aitkens S (1995). A new air displacement method for the determination of human body composition. Med Sci Sports Exerc 27, 1692-1697.
6. Eura Y, Ishihara N, Yokota S & Mihara K (2003). Two mitofusin proteins, mammalian homologues of FZO, with distinct functions are both required for mitochondrial fusion. J Biochem (Tokyo) 134, 333-344.
7. Goto M, Terada S, Kato M, Katoh M, Yokozeki T, Tabata I & Shimokawa T (2000). cDNA Cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats. Biochem Biophys Res Commun 274, 350-354.
8. Grant S, Craig I, Wilson J & Aitchison T (1997). The relationship between 3 km running performance and selected physiological variables. J Sports Sci 15, 403-410.
9. Higuchi R, Fockler C, Dollinger G & Watson R (1993). Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (N Y) 11, 1026-1030.
10. Holloszy JO & Coyle EF (1984). Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J Appl Physiol 56, 831-838.
11. Hood DA (2001). Invited Review: contractile activity-induced mitochondrial biogenesis in skeletal muscle. J Appl Physiol 90, 1137-1157.
12. Huss JM, Kopp RP & Kelly DP (2002). Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha. J Biol Chem 277, 40265-40274.
13. Irrcher I, Adhihetty PJ, Joseph AM, Ljubicic V & Hood DA (2003). Regulation of mitochondrial biogenesis in muscle by endurance exercise. Sports Med 33, 783-793.
14. Johnston SD, Liu X, Zuo F, Eisenbraun TL, Wiley SR, Kraus RJ & Mertz JE (1997). Estrogen-related receptor alpha 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements. Mol Endocrinol 11, 342-352.
15. Kelley DE, He J, Menshikova EV & Ritov VB (2002). Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51, 2944-2950.
16. Kelly DP & Scarpulla RC (2004). Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev 18, 357-368.
17. Knutti D & Kralli A (2001). PGC-1, a versatile coactivator. Trends Endocrinol Metab 12, 360-365.
18. Laganiere J, Tremblay GB, Dufour CR, Giroux S, Rousseau F & Giguere V (2004). A polymorphic autoregulatory hormone response element in the human estrogen-related receptor alpha (ERRalpha) promoter dictates peroxisome proliferator-activated receptor gamma coactivator-1alpha control of ERRalpha expression. J Biol Chem 279, 18504-18510.
19. Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, Michael LF, Puigserver P, Isotani E, Olson EN, Lowell BB, Bassel-Duby R & Spiegelman BM (2002). Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature 418, 797-801.
20. Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES & Spiegelman BM (2004). Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci U S A 101, 6570-6575.
21. Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D & Groop LC (2003). PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genet 34, 267-273.
22. Murakami T, Shimomura Y, Yoshimura A, Sokabe M & Fujitsuka N (1998). Induction of nuclear respiratory factor-1 expression by an acute bout of exercise in rat muscle. Biochim Biophys Acta 1381, 113-122.
23. Norrbom J, Sundberg CJ, Ameln H, Kraus WE, Jansson E & Gustafsson T (2004). PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle. J Appl Physiol 96, 189-194.
24. Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR & Mandarino LJ (2003). Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A 100, 8466-8471.
25. Pilegaard H, Saltin B & Neufer PD (2003). Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. J Physiol 546, 851-858.
26. Puigserver P & Spiegelman BM (2003). Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr Rev 24, 78-90.
27. Russell AP, Feilchenfeldt J, Schreiber S, Praz M, Crettenand A, Gobelet C, Meier CA, Bell DR, Kralli A, Giacobino JP & Deriaz O (2003). Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle. Diabetes 52, 2874-2881.
28. Schreiber SN, Emter R, Hock MB, Knutti D, Cardenas J, Podvinec M, Oakeley EJ & Kralli A (2004). The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha) -induced mitochondrial biogenesis. Proc Natl Acad Sci U S A 101, 6472-6477.
29. Schreiber SN, Knutti D, Brogli K, Uhlmann T & Kralli A (2003). The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha). J Biol Chem 278, 9013-9018.
30. Short KR, Vittone JL, Bigelow ML, Proctor DN, Rizza RA, Coenen-Schimke JM & Nair KS (2003). Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes 52, 1888-1896.
31. Sladek R, Bader JA & Giguere V (1997). The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol Cell Biol 17, 5400-5409.
32. Terada S, Goto M, Kato M, Kawanaka K, Shimokawa T & Tabata I (2002). Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle. Biochem Biophys Res Commun 296, 350-354.
33. Virbasius JV & Scarpulla RC (1991). Transcriptional activation through ETS domain binding sites in the cytochrome c oxidase subunit IV gene. Mol Cell Biol 11, 5631-5638.
34. Vogt M, Puntschart A, Geiser J, Zuleger C, Billeter R & Hoppeler H (2001). Molecular adaptations in human skeletal muscle to endurance training under simulated hypoxic conditions. J Appl Physiol 91, 173-182.
35. Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC & Spiegelman BM (1999). Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98, 115-124.