-
1
-
-
84896723562
-
Worldwide epidemiology of atrial fibrillation: A global burden of disease 2010 study
-
Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, Gillum RF, Kim YH, McAnulty JH Jr, Zheng ZJ, Forouzanfar MH, Naghavi M, Mensah GA, Ezzati M, Murray CJ. Worldwide epidemiology of atrial fibrillation: a global burden of disease 2010 study. Circulation 2014; 129: 837-847
-
(2014)
Circulation
, vol.129
, pp. 837-847
-
-
Chugh, S.S.1
Havmoeller, R.2
Narayanan, K.3
Singh, D.4
Rienstra, M.5
Benjamin, E.J.6
Gillum, R.F.7
Kim, Y.H.8
McAnulty, J.H.9
Zheng, Z.J.10
Forouzanfar, M.H.11
Naghavi, M.12
Mensah, G.A.13
Ezzati, M.14
Murray, C.J.15
-
2
-
-
84892657574
-
Metabolic syndrome remodels electrical activity of the sinoatrial node and produces arrhythmias in rats
-
Albarado-Ibanez A, Avelino-Cruz JE, Velasco M, Torres-Jacome J, Hiriart M. Metabolic syndrome remodels electrical activity of the sinoatrial node and produces arrhythmias in rats. PLoS ONE 2013; 8: e76534
-
(2013)
PLoS ONE
, vol.8
, pp. e76534
-
-
Albarado-Ibanez, A.1
Avelino-Cruz, J.E.2
Velasco, M.3
Torres-Jacome, J.4
Hiriart, M.5
-
3
-
-
84867160101
-
Amp-Activated protein kinase: Potential role in cardiac electrophysiology and arrhythmias
-
Harada M, Nattel SN, Nattel S. Amp-Activated protein kinase: potential role in cardiac electrophysiology and arrhythmias. Circ Arrhythm Electrophysiol 2012; 5: 860-867
-
(2012)
Circ Arrhythm Electrophysiol
, vol.5
, pp. 860-867
-
-
Harada, M.1
Nattel, S.N.2
Nattel, S.3
-
4
-
-
84865846785
-
Amp-Activated protein kinase regulation and biological actions in the heart
-
Zaha VG, Young LH. AMP-Activated protein kinase regulation and biological actions in the heart. Circ Res 2012; 111: 800-814
-
(2012)
Circ Res
, vol.111
, pp. 800-814
-
-
Zaha, V.G.1
Young, L.H.2
-
5
-
-
12144287284
-
Lkb1 is a master kinase that activates 13 kinases of the ampk subfamily, including mark/par-1
-
Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR. LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J 2004; 23: 833-843
-
(2004)
EMBO J
, vol.23
, pp. 833-843
-
-
Lizcano, J.M.1
Göransson, O.2
Toth, R.3
Deak, M.4
Morrice, N.A.5
Boudeau, J.6
Hawley, S.A.7
Udd, L.8
Mäkelä, T.P.9
Hardie, D.G.10
Alessi, D.R.11
-
6
-
-
33646420605
-
Deficiency of lkb1 in heart prevents ischemia-mediated activation of ampkalpha2 but not ampkalpha1
-
Sakamoto K, Zarrinpashneh E, Budas GR, Pouleur AC, Dutta A, Prescott AR, Vanoverschelde JL, Ashworth A, Jovanović A, Alessi DR, Bertrand L. Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1. Am J Physiol Endocrinol Metab 2006; 290: E780-e788
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
, pp. E780-e788
-
-
Sakamoto, K.1
Zarrinpashneh, E.2
Budas, G.R.3
Pouleur, A.C.4
Dutta, A.5
Prescott, A.R.6
Vanoverschelde, J.L.7
Ashworth, A.8
Jovanović, A.9
Alessi, D.R.10
Bertrand, L.11
-
7
-
-
34547828813
-
Specific pattern of lkb1 and phospho-Acetyl-coa carboxylase protein immunostaining in human normal tissues and lung carcinomas
-
Conde E, Suarez-Gauthier A, Garcia-Garcia E, Lopez-Rios F, Lopez-Encuentra A, Garcia-Lujan R, Morente M, Sanchez-Verde L, Sanchez-Cespedes M. Specific pattern of LKB1 and phospho-Acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas. Hum Pathol 2007; 38: 1351-1360
-
(2007)
Hum Pathol
, vol.38
, pp. 1351-1360
-
-
Conde, E.1
Suarez-Gauthier, A.2
Garcia-Garcia, E.3
Lopez-Rios, F.4
Lopez-Encuentra, A.5
Garcia-Lujan, R.6
Morente, M.7
Sanchez-Verde, L.8
Sanchez-Cespedes, M.9
-
8
-
-
0038614742
-
Activation of the tumour suppressor kinase lkb1 by the ste20-like pseudokinase strad
-
Baas AF, Boudeau J, Sapkota GP, Smit L, Medema R, Morrice NA, Alessi DR, Clevers HC. Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. EMBO J 2003; 22: 3062-3072
-
(2003)
EMBO J
, vol.22
, pp. 3062-3072
-
-
Baas, A.F.1
Boudeau, J.2
Sapkota, G.P.3
Smit, L.4
Medema, R.5
Morrice, N.A.6
Alessi, D.R.7
Clevers, H.C.8
-
9
-
-
0141753981
-
Mo25alpha/beta interact with stradalpha/beta enhancing their ability to bind, activate and localize lkb1 in the cytoplasm
-
Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR. MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J 2003; 22: 5102-5114
-
(2003)
EMBO J
, vol.22
, pp. 5102-5114
-
-
Boudeau, J.1
Baas, A.F.2
Deak, M.3
Morrice, N.A.4
Kieloch, A.5
Schutkowski, M.6
Prescott, A.R.7
Clevers, H.C.8
Alessi, D.R.9
-
10
-
-
34748845413
-
Prevalence and specificity of lkb1 genetic alterations in lung cancers
-
Matsumoto S, Iwakawa R, Takahashi K, Kohno T, Nakanishi Y, Matsuno Y, Suzuki K, Nakamoto M, Shimizu E, Minna JD, Yokota J. Prevalence and specificity of LKB1 genetic alterations in lung cancers. Oncogene 2007; 26: 5911-5918
-
(2007)
Oncogene
, vol.26
, pp. 5911-5918
-
-
Matsumoto, S.1
Iwakawa, R.2
Takahashi, K.3
Kohno, T.4
Nakanishi, Y.5
Matsuno, Y.6
Suzuki, K.7
Nakamoto, M.8
Shimizu, E.9
Minna, J.D.10
Yokota, J.11
-
11
-
-
0032495530
-
A serine/threonine kinase gene defective in peutz-jeghers syndrome
-
Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Hö glund P, Järvinen H, Kristo P, Pelin K, Ridanpää M, Salovaara R, Toro T, Bodmer W, Olschwang S, Olsen AS, Stratton MR, de la Chapelle A, Aaltonen LA. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 1998; 391: 184-187
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
Loukola, A.6
Bignell, G.7
Warren, W.8
Aminoff, M.9
Hö Glund, P.10
Järvinen, H.11
Kristo, P.12
Pelin, K.13
Ridanpää, M.14
Salovaara, R.15
Toro, T.16
Bodmer, W.17
Olschwang, S.18
Olsen, A.S.19
Stratton, M.R.20
De La Chapelle, A.21
Aaltonen, L.A.22
more..
-
12
-
-
77951783390
-
Stradalpha deficiency results in aberrant mtorc1 signaling during corticogenesis in humans and mice
-
Orlova KA, Parker WE, Heuer GG, Tsai V, Yoon J, Baybis M, Fenning RS, Strauss K, Crino PB. Stradalpha deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice. J Clin Invest 2010; 120: 1591-1602
-
(2010)
J Clin Invest
, vol.120
, pp. 1591-1602
-
-
Orlova, K.A.1
Parker, W.E.2
Heuer, G.G.3
Tsai, V.4
Yoon, J.5
Baybis, M.6
Fenning, R.S.7
Strauss, K.8
Crino, P.B.9
-
13
-
-
34447637612
-
Polyhydramnios, megalencephaly and symptomatic epilepsy caused by a homozygous 7-kilobase deletion in lyk5
-
Puffenberger EG, Strauss KA, Ramsey KE, Craig DW, Stephan DA, Robinson DL, Hendrickson CL, Gottlieb S, Ramsay DA, Siu VM, Heuer GG, Crino PB, Morton DH. Polyhydramnios, megalencephaly and symptomatic epilepsy caused by a homozygous 7-kilobase deletion in LYK5. Brain 2007; 130: 1929-1941
-
(2007)
Brain
, vol.130
, pp. 1929-1941
-
-
Puffenberger, E.G.1
Strauss, K.A.2
Ramsey, K.E.3
Craig, D.W.4
Stephan, D.A.5
Robinson, D.L.6
Hendrickson, C.L.7
Gottlieb, S.8
Ramsay, D.A.9
Siu, V.M.10
Heuer, G.G.11
Crino, P.B.12
Morton, D.H.13
-
14
-
-
0035903028
-
Vascular abnormalities and deregulation of vegf in lkb1-deficient mice
-
Ylikorkala A, Rossi DJ, Korsisaari N, Luukko K, Alitalo K, Henkemeyer M, Mäkelä TP. Vascular abnormalities and deregulation of VEGF in LKB1-deficient mice. Science 2001; 293: 1323-1326
-
(2001)
Science
, vol.293
, pp. 1323-1326
-
-
Ylikorkala, A.1
Rossi, D.J.2
Korsisaari, N.3
Luukko, K.4
Alitalo, K.5
Henkemeyer, M.6
Mäkelä, T.P.7
-
15
-
-
83455245205
-
The tumor suppressor kinase lkb1: Lessons from mouse models
-
Ollila S, Mäkelä TP. The tumor suppressor kinase LKB1: lessons from mouse models. J Mol Cell Biol 2011; 3: 330-340
-
(2011)
J Mol Cell Biol
, vol.3
, pp. 330-340
-
-
Ollila, S.1
Mäkelä, T.P.2
-
16
-
-
33846003474
-
Skeletal muscle and heart lkb1 deficiency causes decreased voluntary running and reduced muscle mitochondrial marker enzyme expression in mice
-
Thomson DM, Porter BB, Tall JH, Kim HJ, Barrow JR, Winder WW. Skeletal muscle and heart LKB1 deficiency causes decreased voluntary running and reduced muscle mitochondrial marker enzyme expression in mice. Am J Physiol Endocrinol Metab 2007; 292: E196-E202
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
, pp. E196-E202
-
-
Thomson, D.M.1
Porter, B.B.2
Tall, J.H.3
Kim, H.J.4
Barrow, J.R.5
Winder, W.W.6
-
17
-
-
77953169730
-
Skeletal muscle dysfunction in muscle-specific lkb1 knockout mice
-
Thomson DM, Hancock CR, Evanson BG, Kenney SG, Malan BB, Mongillo AD, Brown JD, Hepworth S, Fillmore N, Parcell AC, Kooyman DL, Winder WW. Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice. J Appl Physiol 2010; 108: 1775-1785
-
(2010)
J Appl Physiol
, vol.108
, pp. 1775-1785
-
-
Thomson, D.M.1
Hancock, C.R.2
Evanson, B.G.3
Kenney, S.G.4
Malan, B.B.5
Mongillo, A.D.6
Brown, J.D.7
Hepworth, S.8
Fillmore, N.9
Parcell, A.C.10
Kooyman, D.L.11
Winder, W.W.12
-
18
-
-
72149093508
-
Cardiac-specific deletion of lkb1 leads to hypertrophy and dysfunction
-
Ikeda Y, Sato K, Pimentel DR, Sam F, Shaw RJ, Dyck JR, Walsh K. Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. J Biol Chem 2009; 284: 35839-35849
-
(2009)
J Biol Chem
, vol.284
, pp. 35839-35849
-
-
Ikeda, Y.1
Sato, K.2
Pimentel, D.R.3
Sam, F.4
Shaw, R.J.5
Dyck, J.R.6
Walsh, K.7
-
19
-
-
0037068461
-
Loss of the lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
-
Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA. Loss of the LKB1 tumour suppressor provokes intestinal polyposis but resistance to transformation. Nature 2002; 419: 162-167
-
(2002)
Nature
, vol.419
, pp. 162-167
-
-
Bardeesy, N.1
Sinha, M.2
Hezel, A.F.3
Signoretti, S.4
Hathaway, N.A.5
Sharpless, N.E.6
Loda, M.7
Carrasco, D.R.8
DePinho, R.A.9
-
20
-
-
0030878260
-
Gene recombination in postmitotic cells
-
Agah R, Frenkel PA, French BA, Michael LH, Overbeek PA, Schneider MD. Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest 1997; 100: 169-179
-
(1997)
Targeted Expression of Cre Recombinase Provokes Cardiac-restricted, Site-specific Rearrangement in Adult Ventricular Muscle in Vivo. J Clin Invest
, vol.100
, pp. 169-179
-
-
Agah, R.1
Frenkel, P.A.2
French, B.A.3
Michael, L.H.4
Overbeek, P.A.5
Schneider, M.D.6
-
21
-
-
78149279712
-
Amp-Activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
-
Russell RR, Li J, Coven D, Pypaert M, Zechner C, Palmeri M, Giordano F, Mu J, Birnbaum M, Young L. Amp-Activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest 2004; 114: 495-503
-
(2004)
J Clin Invest
, vol.114
, pp. 495-503
-
-
Russell, R.R.1
Li, J.2
Coven, D.3
Pypaert, M.4
Zechner, C.5
Palmeri, M.6
Giordano, F.7
Mu, J.8
Birnbaum, M.9
Young, L.10
-
22
-
-
77955457622
-
Functional anatomy of the murine sinus node: High-resolution optical mapping of ankyrin-b heterozygous mice
-
Glukhov AV, Fedorov VV, Anderson ME, Mohler PJ, Efimov IR. Functional anatomy of the murine sinus node: high-resolution optical mapping of ankyrin-B heterozygous mice. Am J Physiol Heart Circ Physiol 2010; 299: H482-H491
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
, pp. H482-H491
-
-
Glukhov, A.V.1
Fedorov, V.V.2
Anderson, M.E.3
Mohler, P.J.4
Efimov, I.R.5
-
23
-
-
34547909627
-
Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure
-
Akar FG, Nass RD, Hahn S, Cingolani E, Shah M, Hesketh GG, DiSilvestre D, Tunin RS, Kass DA, Tomaselli GF. Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure. Am J Physiol Heart Circ Physiol 2007; 293: H1223-H1230
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, pp. H1223-H1230
-
-
Akar, F.G.1
Nass, R.D.2
Hahn, S.3
Cingolani, E.4
Shah, M.5
Hesketh, G.G.6
DiSilvestre, D.7
Tunin, R.S.8
Kass, D.A.9
Tomaselli, G.F.10
-
24
-
-
79956298543
-
A small molecule ampk activator protects the heart against ischemia-reperfusion injury
-
Kim AS, Miller EJ, Wright TM, Li J, Qi D, Atsina K, Zaha V, Sakamoto K, Young LH. A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. J Mol Cell Cardiol 2011; 51: 24-32
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 24-32
-
-
Kim, A.S.1
Miller, E.J.2
Wright, T.M.3
Li, J.4
Qi, D.5
Atsina, K.6
Zaha, V.7
Sakamoto, K.8
Young, L.H.9
-
25
-
-
84884188524
-
Isolation and culture of neonatal mouse cardiomyocytes
-
Ehler E, Moore-Morris T, Lange S. Isolation and culture of neonatal mouse cardiomyocytes. J Vis Exp 2013; doi: 10.3791/50154
-
(2013)
J Vis Exp
-
-
Ehler, E.1
Moore-Morris, T.2
Lange, S.3
-
26
-
-
84922392783
-
Ankyrin-g coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo
-
Makara MA, Curran J, Little SC, Musa H, Polina I, Smith SA, Wright PJ, Unudurthi SD, Snyder J, Bennett V, Hund TJ, Mohler PJ. Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo. Circ Res 2014; 115: 929-938
-
(2014)
Circ Res
, vol.115
, pp. 929-938
-
-
Makara, M.A.1
Curran, J.2
Little, S.C.3
Musa, H.4
Polina, I.5
Smith, S.A.6
Wright, P.J.7
Unudurthi, S.D.8
Snyder, J.9
Bennett, V.10
Hund, T.J.11
Mohler, P.J.12
-
27
-
-
72849146175
-
Cardiac macrophage migration inhibitory factor inhibits jnk pathway activation and injury during ischemia/reperfusion
-
Qi D, Hu X, Wu X, Merk M, Leng L, Bucala R, Young L. Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion. J Clin Invest 2009; 119: 3807-3816
-
(2009)
J Clin Invest
, vol.119
, pp. 3807-3816
-
-
Qi, D.1
Hu, X.2
Wu, X.3
Merk, M.4
Leng, L.5
Bucala, R.6
Young, L.7
-
28
-
-
77953808195
-
Ablation of lkb1 in the heart leads to energy deprivation and impaired cardiac function
-
Jessen N, Koh HJ, Folmes CD, Wagg C, Fujii N, Løfgren B, Wolf CM, Berul CI, Hirshman MF, Lopaschuk GD, Goodyear LJ. Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function. Biochim Biophys Acta 2010; 1802: 593-600
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 593-600
-
-
Jessen, N.1
Koh, H.J.2
Folmes, C.D.3
Wagg, C.4
Fujii, N.5
Løfgren, B.6
Wolf, C.M.7
Berul, C.I.8
Hirshman, M.F.9
Lopaschuk, G.D.10
Goodyear, L.J.11
-
29
-
-
50949115126
-
Atrial remodeling and atrial fibrillation: Mechanisms and implications
-
Nattel S, Burstein B, Dobrev D. Atrial remodeling and atrial fibrillation: mechanisms and implications. Circ Arrhythm Electrophysiol 2008; 1: 62-73
-
(2008)
Circ Arrhythm Electrophysiol
, vol.1
, pp. 62-73
-
-
Nattel, S.1
Burstein, B.2
Dobrev, D.3
-
30
-
-
0028607266
-
Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light
-
Whittaker P, Kloner RA, Boughner DR, Pickering JG. Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Basic Res Cardiol 1994; 89: 397-410
-
(1994)
Basic Res Cardiol
, vol.89
, pp. 397-410
-
-
Whittaker, P.1
Kloner, R.A.2
Boughner, D.R.3
Pickering, J.G.4
-
31
-
-
56749180988
-
Paroxysmal atrial fibrillation is associated with increased intra-Atrial conduction delay
-
Pytkowski M, Jankowska A, Maciag A, Kowalik I, Sterlinski M, Szwed H, Saumarez RC. Paroxysmal atrial fibrillation is associated with increased intra-Atrial conduction delay. Europace 2008; 10: 1415-1420
-
(2008)
Europace
, vol.10
, pp. 1415-1420
-
-
Pytkowski, M.1
Jankowska, A.2
Maciag, A.3
Kowalik, I.4
Sterlinski, M.5
Szwed, H.6
Saumarez, R.C.7
-
32
-
-
59849102624
-
Regulation of cl(2) secretion by ampk in vivo
-
Kongsuphol P, Hieke B, Ousingsawat J, Almaca J, Viollet B, Schreiber R, Kunzelmann K. Regulation of Cl(2) secretion by AMPK in vivo. Pflugers Arch 2009; 457: 1071-1078
-
(2009)
Pflugers Arch
, vol.457
, pp. 1071-1078
-
-
Kongsuphol, P.1
Hieke, B.2
Ousingsawat, J.3
Almaca, J.4
Viollet, B.5
Schreiber, R.6
Kunzelmann, K.7
-
33
-
-
84857030688
-
Sgt1 acts via an lkb1/ampk pathway to establish cortical polarity in larval neuroblasts
-
Andersen RO, Turnbull DW, Johnson EA, Doe CQ. Sgt1 acts via an LKB1/AMPK pathway to establish cortical polarity in larval neuroblasts. Dev Biol 2012; 363: 258-265
-
(2012)
Dev Biol
, vol.363
, pp. 258-265
-
-
Andersen, R.O.1
Turnbull, D.W.2
Johnson, E.A.3
Doe, C.Q.4
-
34
-
-
0030792079
-
Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system
-
Delorme B, Dahl E, Jarry-Guichard T, Briand JP, Willecke K, Gros D, Théveniau-Ruissy M. Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system. Circ Res 1997; 81: 423-437
-
(1997)
Circ Res
, vol.81
, pp. 423-437
-
-
Delorme, B.1
Dahl, E.2
Jarry-Guichard, T.3
Briand, J.P.4
Willecke, K.5
Gros, D.6
Théveniau-Ruissy, M.7
-
35
-
-
0030013202
-
Connexins, connexons, and intercellular communication
-
Goodenough DA, Goliger JA, Paul DL. Connexins, connexons, and intercellular communication. Annu Rev Biochem 1996; 65: 475-502
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 475-502
-
-
Goodenough, D.A.1
Goliger, J.A.2
Paul, D.L.3
-
36
-
-
0032567957
-
Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice
-
Kirchhoff S, Nelles E, Hagendorff A, Krüger O, Traub O, Willecke K. Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr Biol 1998; 8: 299-302
-
(1998)
Curr Biol
, vol.8
, pp. 299-302
-
-
Kirchhoff, S.1
Nelles, E.2
Hagendorff, A.3
Krüger, O.4
Traub, O.5
Willecke, K.6
-
37
-
-
0032567887
-
Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
-
Simon AM, Goodenough DA, Paul DL. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr Biol 1998; 8: 295-298
-
(1998)
Curr Biol
, vol.8
, pp. 295-298
-
-
Simon, A.M.1
Goodenough, D.A.2
Paul, D.L.3
-
38
-
-
24944471422
-
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene scn5a
-
Lei M, Goddard C, Liu J, Léoni AL, Royer A, Fung SS, Xiao G, Ma A, Zhang H, Charpentier F, Vandenberg JI, Colledge WH, Grace AA, Huang CL. Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a. J Physiol 2005; 567: 387-400
-
(2005)
J Physiol
, vol.567
, pp. 387-400
-
-
Lei, M.1
Goddard, C.2
Liu, J.3
Léoni, A.L.4
Royer, A.5
Fung, S.S.6
Xiao, G.7
Ma, A.8
Zhang, H.9
Charpentier, F.10
Vandenberg, J.I.11
Colledge, W.H.12
Grace, A.A.13
Huang, C.L.14
-
39
-
-
18344362987
-
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene scn5a
-
Papadatos GA, Wallerstein PM, Head CE, Ratcliff R, Brady PA, Benndorf K, Saumarez RC, Trezise AE, Huang CL, Vandenberg JI, Colledge WH, Grace AA. Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci USA 2002; 99: 6210-6215
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6210-6215
-
-
Papadatos, G.A.1
Wallerstein, P.M.2
Head, C.E.3
Ratcliff, R.4
Brady, P.A.5
Benndorf, K.6
Saumarez, R.C.7
Trezise, A.E.8
Huang, C.L.9
Vandenberg, J.I.10
Colledge, W.H.11
Grace, A.A.12
-
40
-
-
84885537887
-
The connexin40a96s mutation from a patient with atrial fibrillation causes decreased atrial conduction velocities and sustained episodes of induced atrial fibrillation in mice
-
Lubkemeier I, Andrie R, Lickfett L, Bosen F, Stockigt F, Dobrowolski R, Draffehn AM, Fregeac J, Schultze JL, Bukauskas FF, Schrickel JW, Willecke K. The connexin40a96s mutation from a patient with atrial fibrillation causes decreased atrial conduction velocities and sustained episodes of induced atrial fibrillation in mice. J Mol Cell Cardiol 2013; 65: 19-32
-
(2013)
J Mol Cell Cardiol
, vol.65
, pp. 19-32
-
-
Lubkemeier, I.1
Andrie, R.2
Lickfett, L.3
Bosen, F.4
Stockigt, F.5
Dobrowolski, R.6
Draffehn, A.M.7
Fregeac, J.8
Schultze, J.L.9
Bukauskas, F.F.10
Schrickel, J.W.11
Willecke, K.12
-
41
-
-
84859312522
-
Reduced heterogeneous expression of cx43 results in decreased nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional cx43 knockout mice
-
Jansen JA, Noorman M, Musa H, Stein M, de Jong S, van der Nagel R, Hund TJ, Mohler PJ, Vos MA, van Veen TA, de Bakker JM, Delmar M, van Rijen HV. Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice. Heart Rhythm 2012; 9: 600-607
-
(2012)
Heart Rhythm
, vol.9
, pp. 600-607
-
-
Jansen, J.A.1
Noorman, M.2
Musa, H.3
Stein, M.4
De Jong, S.5
Van Der Nagel, R.6
Hund, T.J.7
Mohler, P.J.8
Vos, M.A.9
Van Veen, T.A.10
De Bakker, J.M.11
Delmar, M.12
Van Rijen, H.V.13
-
42
-
-
23044463854
-
Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation
-
Gaborit N, Steenman M, Lamirault G, Le Meur N, Le Bouter S, Lande G, Leger J, Charpentier F, Christ T, Dobrev D, Escande D, Nattel S, Demolombe S. Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation. Circulation 2005; 112: 471-481
-
(2005)
Circulation
, vol.112
, pp. 471-481
-
-
Gaborit, N.1
Steenman, M.2
Lamirault, G.3
Le Meur, N.4
Le Bouter, S.5
Lande, G.6
Leger, J.7
Charpentier, F.8
Christ, T.9
Dobrev, D.10
Escande, D.11
Nattel, S.12
Demolombe, S.13
-
43
-
-
84992243318
-
Lkb1 knockout mouse develops spontaneous atrial fibrillation and provides mechanistic insights into human disease process
-
Ozcan C, Battaglia E, Young R, Suzuki G. LKB1 knockout mouse develops spontaneous atrial fibrillation and provides mechanistic insights into human disease process. J Am Heart Assoc 2015; 4: e001733
-
(2015)
J Am Heart Assoc
, vol.4
, pp. e001733
-
-
Ozcan, C.1
Battaglia, E.2
Young, R.3
Suzuki, G.4
-
44
-
-
35448966624
-
Spatial distribution of fibrosis governs fibrillation wave dynamics in the posterior left atrium during heart failure
-
Tanaka K, Zlochiver S, Vikstrom KL, Yamazaki M, Moreno J, Klos M, Zaitsev AV, Vaidyanathan R, Auerbach DS, Landas S, Guiraudon G, Jalife J, Berenfeld O, Kalifa J. Spatial distribution of fibrosis governs fibrillation wave dynamics in the posterior left atrium during heart failure. Circ Res 2007; 101: 839-847
-
(2007)
Circ Res
, vol.101
, pp. 839-847
-
-
Tanaka, K.1
Zlochiver, S.2
Vikstrom, K.L.3
Yamazaki, M.4
Moreno, J.5
Klos, M.6
Zaitsev, A.V.7
Vaidyanathan, R.8
Auerbach, D.S.9
Landas, S.10
Guiraudon, G.11
Jalife, J.12
Berenfeld, O.13
Kalifa, J.14
-
45
-
-
0034677796
-
Atrial but not ventricular fibrosis in mice expressing a mutant transforming growth factorbeta(1) transgene in the heart
-
Nakajima H, Nakajima HO, Salcher O, Dittié AS, Dembowsky K, Jing S, Field LJ. Atrial but not ventricular fibrosis in mice expressing a mutant transforming growth factorbeta(1) transgene in the heart. Circ Res 2000; 86: 571-579
-
(2000)
Circ Res
, vol.86
, pp. 571-579
-
-
Nakajima, H.1
Nakajima, H.O.2
Salcher, O.3
Dittié, A.S.4
Dembowsky, K.5
Jing, S.6
Field, L.J.7
-
46
-
-
4944249400
-
Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy
-
Akar FG, Spragg DD, Tunin RS, Kass DA, Tomaselli GF. Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy. Circ Res 2004; 95: 717-725
-
(2004)
Circ Res
, vol.95
, pp. 717-725
-
-
Akar, F.G.1
Spragg, D.D.2
Tunin, R.S.3
Kass, D.A.4
Tomaselli, G.F.5
-
47
-
-
84938861015
-
Ampk deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism
-
Sung MM, Zordoky BN, Bujak AL, Lally JS, Fung D, Young ME, Horman S, Miller EJ, Light PE, Kemp BE, Steinberg GR, Dyck JR. AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism. Cardiovasc Res 2015; 107: 235-245
-
(2015)
Cardiovasc Res
, vol.107
, pp. 235-245
-
-
Sung, M.M.1
Zordoky, B.N.2
Bujak, A.L.3
Lally, J.S.4
Fung, D.5
Young, M.E.6
Horman, S.7
Miller, E.J.8
Light, P.E.9
Kemp, B.E.10
Steinberg, G.R.11
Dyck, J.R.12
-
48
-
-
79960620794
-
Different expression of the catalytic alpha subunits of the amp activated protein kinase-An immunohistochemical study in human tissue
-
Quentin T, Kitz J, Steinmetz M, Poppe A, Bar K, Kratzner R. Different expression of the catalytic alpha subunits of the amp activated protein kinase-An immunohistochemical study in human tissue. Histol Histopathol 2011; 26: 589-596
-
(2011)
Histol Histopathol
, vol.26
, pp. 589-596
-
-
Quentin, T.1
Kitz, J.2
Steinmetz, M.3
Poppe, A.4
Bar, K.5
Kratzner, R.6
-
49
-
-
0035859215
-
Identification of a gene responsible for familial wolff-Parkinson-white syndrome
-
Gollob MH, Green MS, Tang AS, Gollob T, Karibe A, Ali Hassan AS, Ahmad F, Lozado R, Shah G, Fananapazir L, Bachinski LL, Roberts R. Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. N Engl J Med 2001; 344: 1823-1831
-
(2001)
N Engl J Med
, vol.344
, pp. 1823-1831
-
-
Gollob, M.H.1
Green, M.S.2
Tang, A.S.3
Gollob, T.4
Karibe, A.5
Ali Hassan, A.S.6
Ahmad, F.7
Lozado, R.8
Shah, G.9
Fananapazir, L.10
Bachinski, L.L.11
Roberts, R.12
-
50
-
-
0037782349
-
Transgenic mice overexpressing mutant prkag2 define the cause of wolff-Parkinson-white syndrome in glycogen storage cardiomyopathy
-
Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG. Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy. Circulation 2003; 107: 2850-2856
-
(2003)
Circulation
, vol.107
, pp. 2850-2856
-
-
Arad, M.1
Moskowitz, I.P.2
Patel, V.V.3
Ahmad, F.4
Perez-Atayde, A.R.5
Sawyer, D.B.6
Walter, M.7
Li, G.H.8
Burgon, P.G.9
Maguire, C.T.10
Stapleton, D.11
Schmitt, J.P.12
Guo, X.X.13
Pizard, A.14
Kupershmidt, S.15
Roden, D.M.16
Berul, C.I.17
Seidman, C.E.18
Seidman, J.G.19
-
51
-
-
79953767585
-
A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation
-
Wirka RC, Gore S, VanWagoner DR, Arking DE, Lubitz SA, Lunetta KL, Benjamin EJ, Alonso A, Ellinor PT, Barnard J, Chung MK, Smith JD. A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation. Circ Arrhythm Electrophysiol 2011; 4: 87-93
-
(2011)
Circ Arrhythm Electrophysiol
, vol.4
, pp. 87-93
-
-
Wirka, R.C.1
Gore, S.2
VanWagoner, D.R.3
Arking, D.E.4
Lubitz, S.A.5
Lunetta, K.L.6
Benjamin, E.J.7
Alonso, A.8
Ellinor, P.T.9
Barnard, J.10
Chung, M.K.11
Smith, J.D.12
-
52
-
-
33845983622
-
A common polymorphism in scn5a is associated with lone atrial fibrillation
-
Chen LY, Ballew JD, Herron KJ, Rodeheffer RJ, Olson TM. A common polymorphism in Scn5a is associated with lone atrial fibrillation. Clin Pharmacol Ther 2007; 81: 35-41
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 35-41
-
-
Chen, L.Y.1
Ballew, J.D.2
Herron, K.J.3
Rodeheffer, R.J.4
Olson, T.M.5
-
53
-
-
37549043581
-
Cardiac sodium channel mutation in atrial fibrillation
-
Ellinor PT, Nam EG, Shea MA, Milan DJ, Ruskin JN, MacRae CA. Cardiac sodium channel mutation in atrial fibrillation. Heart Rhythm 2008; 5: 99-105
-
(2008)
Heart Rhythm
, vol.5
, pp. 99-105
-
-
Ellinor, P.T.1
Nam, E.G.2
Shea, M.A.3
Milan, D.J.4
Ruskin, J.N.5
MacRae, C.A.6
-
54
-
-
84866643004
-
High prevalence of long qt syndrome-Associated scn5a variants in patients with early-onset lone atrial fibrillation
-
Olesen MS, Yuan L, Liang B, Holst AG, Nielsen N, Nielsen JB, Hedley PL, Christiansen M, Olesen SP, Haunso S, Schmitt N, Jespersen T, Svendsen JH. High prevalence of long QT syndrome-Associated Scn5a variants in patients with early-onset lone atrial fibrillation. Circulation 2012; 5: 450-459
-
(2012)
Circulation
, vol.5
, pp. 450-459
-
-
Olesen, M.S.1
Yuan, L.2
Liang, B.3
Holst, A.G.4
Nielsen, N.5
Nielsen, J.B.6
Hedley, P.L.7
Christiansen, M.8
Olesen, S.P.9
Haunso, S.10
Schmitt, N.11
Jespersen, T.12
Svendsen, J.H.13
|