메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

Deficiency of Capicua disrupts bile acid homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

AUTACOID; BILE ACID; CIC PROTEIN, MOUSE; CYTOKINE; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 84943376843     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep08272     Document Type: Article
Times cited : (27)

References (45)
  • 1
    • 0343986271 scopus 로고    scopus 로고
    • Relief of gene repression by torso RTK signaling: Role of capicua in Drosophila terminal and dorsoventral patterning
    • Jiménez, G., Guichet, A., Ephrussi, A. & Casanova, J. Relief of gene repression by torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning. Genes Dev. 14, 224-231 (2000).
    • (2000) Genes Dev , vol.14 , pp. 224-231
    • Jiménez, G.1    Guichet, A.2    Ephrussi, A.3    Casanova, J.4
  • 2
    • 84861209129 scopus 로고    scopus 로고
    • The Capicua repressor-A general sensor of RTK signaling in development and disease
    • Jiménez, G., Shvartsman, S. Y. & Paroush, Z. The Capicua repressor-a general sensor of RTK signaling in development and disease. J. Cell. Sci. 125, 1383-1391 (2012).
    • (2012) J. Cell. Sci. , vol.125 , pp. 1383-1391
    • Jiménez, G.1    Shvartsman, S.Y.2    Paroush, Z.3
  • 3
    • 33745283008 scopus 로고    scopus 로고
    • Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation
    • Kawamura-Saito, M. et al. Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation. Hum. Mol. Genet. 15, 2125-2137 (2006).
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 2125-2137
    • Kawamura-Saito, M.1
  • 4
    • 79951522309 scopus 로고    scopus 로고
    • Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
    • Ajuria, L. et al. Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila. Development 138, 915-924 (2011).
    • (2011) Development , vol.138 , pp. 915-924
    • Ajuria, L.1
  • 5
    • 80555125089 scopus 로고    scopus 로고
    • Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua
    • Fryer, J. D. et al. Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua. Science 334, 690-693 (2011).
    • (2011) Science , vol.334 , pp. 690-693
    • Fryer, J.D.1
  • 6
    • 33749993417 scopus 로고    scopus 로고
    • The consensus coding sequences of human breast and colorectal cancers
    • Sjöblom, T. et al. The consensus coding sequences of human breast and colorectal cancers. Science 314, 268-274 (2006).
    • (2006) Science , vol.314 , pp. 268-274
    • Sjöblom, T.1
  • 7
    • 77955660663 scopus 로고    scopus 로고
    • Diverse somatic mutation patterns and pathway alterations in human cancers
    • Kan, Z. et al. Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 466, 869-873 (2010).
    • (2010) Nature , vol.466 , pp. 869-873
    • Kan, Z.1
  • 8
    • 84868206005 scopus 로고    scopus 로고
    • Oligodendrogliomas: New insights from the genetics and perspectives
    • Alentorn, A., Sanson, M. & Idbaih, A. Oligodendrogliomas: new insights from the genetics and perspectives. Curr Opin Oncol 24, 687-693 (2012).
    • (2012) Curr Opin Oncol , vol.24 , pp. 687-693
    • Alentorn, A.1    Sanson, M.2    Idbaih, A.3
  • 10
    • 78751532247 scopus 로고    scopus 로고
    • ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicuá
    • Dissanayake, K. et al. ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicuá. Biochem. J. 433, 515-525 (2011).
    • (2011) Biochem. J. , vol.433 , pp. 515-525
    • Dissanayake, K.1
  • 11
    • 80054734186 scopus 로고    scopus 로고
    • ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization
    • Lee, Y. et al. ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Dev. Cell 21, 746-757 (2011).
    • (2011) Dev. Cell , vol.21 , pp. 746-757
    • Lee, Y.1
  • 12
    • 78650793157 scopus 로고    scopus 로고
    • Bile acids induce inflammatory genes in hepatocytes: A novel mechanism of inflammation during obstructive cholestasis
    • Allen, K., Jaeschke, H. & Copple, B. L. Bile acids induce inflammatory genes in hepatocytes: A novel mechanism of inflammation during obstructive cholestasis. Am. J. Pathol. 178, 175-186 (2011).
    • (2011) Am. J. Pathol. , vol.178 , pp. 175-186
    • Allen, K.1    Jaeschke, H.2    Copple, B.L.3
  • 13
    • 77951522428 scopus 로고    scopus 로고
    • The role of inflammation in cholestasis: Clinical and basic aspects
    • Kosters, A. & Karpen, S. J. The role of inflammation in cholestasis: clinical and basic aspects. Semin. Liver Dis. 30, 186-194 (2010).
    • (2010) Semin. Liver Dis. , vol.30 , pp. 186-194
    • Kosters, A.1    Karpen, S.J.2
  • 14
    • 27444434833 scopus 로고    scopus 로고
    • Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver
    • Zollner, G. et al. Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver. Am. J. Physiol. Gastrointest. Liver Physiol. 289, G798-805 (2005).
    • (2005) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.289 , pp. G798-G805
    • Zollner, G.1
  • 15
    • 0034664729 scopus 로고    scopus 로고
    • Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
    • Sinal, C. J. et al. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102, 731-744 (2000).
    • (2000) Cell , vol.102 , pp. 731-744
    • Sinal, C.J.1
  • 16
    • 49149090637 scopus 로고    scopus 로고
    • Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress
    • Bochkis, I. M. et al. Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress. Nat. Med. 14, 828-836 (2008).
    • (2008) Nat. Med. , vol.14 , pp. 828-836
    • Bochkis, I.M.1
  • 17
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for annotation, visualization, and integrated discovery
    • Dennis, G. Jr. et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4, P3 (2003).
    • (2003) Genome Biol , vol.4 , pp. 3
    • Dennis, G.1
  • 18
    • 53049089913 scopus 로고    scopus 로고
    • Welcoming Foxa2 in the bile acid entourage
    • Moschetta, A. Welcoming Foxa2 in the bile acid entourage. Cell Metab. 8, 276-278 (2008).
    • (2008) Cell Metab , vol.8 , pp. 276-278
    • Moschetta, A.1
  • 19
    • 23044436687 scopus 로고    scopus 로고
    • CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice
    • Wagner, M. et al. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice. Hepatology 42, 420-430 (2005).
    • (2005) Hepatology , vol.42 , pp. 420-430
    • Wagner, M.1
  • 20
    • 10344224570 scopus 로고    scopus 로고
    • The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity
    • Zhang, J., Huang, W., Qatanani, M., Evans, R. M. &Moore, D. D. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. J. Biol. Chem. 279, 49517-49522 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 49517-49522
    • Zhang, J.1    Huang, W.2    Qatanani, M.3    Evans, R.M.4    Moore, D.D.5
  • 21
    • 11244327692 scopus 로고    scopus 로고
    • Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice
    • Uppal, H. et al. Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice. Hepatology 41, 168-176 (2005).
    • (2005) Hepatology , vol.41 , pp. 168-176
    • Uppal, H.1
  • 22
    • 0032555487 scopus 로고    scopus 로고
    • Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter
    • Song, C. S. et al. Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter. J. Biol. Chem. 273, 21856-21866 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 21856-21866
    • Song, C.S.1
  • 23
    • 0034671554 scopus 로고    scopus 로고
    • Feedback inhibition of the retinaldehyde dehydrogenase gene ALDH1 by retinoic acid through retinoic acid receptor alpha and CCAAT/enhancer-binding protein beta
    • Elizondo, G., Corchero, J., Sterneck, E.&Gonzalez, F. J. Feedback inhibition of the retinaldehyde dehydrogenase gene ALDH1 by retinoic acid through retinoic acid receptor alpha and CCAAT/enhancer-binding protein beta. J. Biol. Chem. 275, 39747-39753 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 39747-39753
    • Elizondo, G.1    Corchero, J.2    Sterneck, E.3    Gonzalez, F.J.4
  • 24
    • 47749111708 scopus 로고    scopus 로고
    • Liver-enriched transcription factors and their role in regulating UDP glucuronosyltransferase gene expression
    • Gardner-Stephen, D. A. & Mackenzie, P. I. Liver-enriched transcription factors and their role in regulating UDP glucuronosyltransferase gene expression. Curr. Drug Metab. 9, 439-452 (2008).
    • (2008) Curr. Drug Metab. , vol.9 , pp. 439-452
    • Gardner-Stephen, D.A.1    Mackenzie, P.I.2
  • 25
    • 44149115226 scopus 로고    scopus 로고
    • Forkhead box A2-mediated regulation of female-predominant expression of the mouse Cyp2b9 gene
    • Hashita, T. et al. Forkhead box A2-mediated regulation of female-predominant expression of the mouse Cyp2b9 gene. Drug Metab. Dispos. 36, 1080-1087 (2008).
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 1080-1087
    • Hashita, T.1
  • 26
    • 45649084346 scopus 로고    scopus 로고
    • Differential regulation of human hepatic flavin containing monooxygenase 3 (FMO3) by CCAAT/enhancer-binding protein beta (C/EBPbeta) liver inhibitory and liver activating proteins
    • Klick, D. E., Shadley, J. D. & Hines, R. N. Differential regulation of human hepatic flavin containing monooxygenase 3 (FMO3) by CCAAT/enhancer-binding protein beta (C/EBPbeta) liver inhibitory and liver activating proteins. Biochem. Pharmacol. 76, 268-278 (2008).
    • (2008) Biochem. Pharmacol. , vol.76 , pp. 268-278
    • Klick, D.E.1    Shadley, J.D.2    Hines, R.N.3
  • 27
    • 78149496291 scopus 로고    scopus 로고
    • HNF4a-role in drug metabolism and potential drug target?
    • Hwang-Verslues, W. W. & Sladek, F. M. HNF4a-role in drug metabolism and potential drug target? Curr Opin Pharmacol 10, 698-705 (2010).
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 698-705
    • Hwang-Verslues, W.W.1    Sladek, F.M.2
  • 28
    • 63849258680 scopus 로고    scopus 로고
    • Induction of mouse UDPglucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2
    • Buckley, D. B. & Klaassen, C. D. Induction of mouse UDPglucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2. Drug Metab. Dispos. 37, 847-856 (2009).
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 847-856
    • Buckley, D.B.1    Klaassen, C.D.2
  • 29
    • 84862689443 scopus 로고    scopus 로고
    • Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARa-, and Nrf2-null mice
    • Aleksunes, L. M. & Klaassen, C. D. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARa-, and Nrf2-null mice. Drug Metab. Dispos. 40, 1366-1379 (2012).
    • (2012) Drug Metab. Dispos. , vol.40 , pp. 1366-1379
    • Aleksunes, L.M.1    Klaassen, C.D.2
  • 30
    • 84862107719 scopus 로고    scopus 로고
    • Transcription factormediated regulation of carboxylesterase enzymes in livers of mice
    • Zhang, Y., Cheng, X., Aleksunes, L. & Klaassen, C. D. Transcription factormediated regulation of carboxylesterase enzymes in livers of mice. Drug Metab. Dispos. 40, 1191-1197 (2012).
    • (2012) Drug Metab. Dispos. , vol.40 , pp. 1191-1197
    • Zhang, Y.1    Cheng, X.2    Aleksunes, L.3    Klaassen, C.D.4
  • 31
    • 0034035667 scopus 로고    scopus 로고
    • Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver
    • Wan, Y. J. et al. Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver. Mol. Cell. Biol. 20, 4436-4444 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4436-4444
    • Wan, Y.J.1
  • 32
    • 33845481284 scopus 로고    scopus 로고
    • Xenobiotic- And Vitamin D-responsive induction of the steroid/bile acid-sulfotransferase Sult2A1 in young and old mice: The role of a gene enhancer in the liver chromatin
    • Seo, Y.-K. et al. Xenobiotic- And vitamin D-responsive induction of the steroid/bile acid-sulfotransferase Sult2A1 in young and old mice: The role of a gene enhancer in the liver chromatin. Gene 386, 218-223 (2007).
    • (2007) Gene , vol.386 , pp. 218-223
    • Seo, Y.-K.1
  • 34
    • 33846426043 scopus 로고    scopus 로고
    • Sepsis-induced cholestasis
    • Chand, N. & Sanyal, A. J. Sepsis-induced cholestasis. Hepatology 45, 230-241 (2007).
    • (2007) Hepatology , vol.45 , pp. 230-241
    • Chand, N.1    Sanyal, A.J.2
  • 35
    • 0028931318 scopus 로고
    • Regulation of the human TNF promoter by the transcription factor Ets
    • Krämer, B., Wiegmann, K. & Krönke, M. Regulation of the human TNF promoter by the transcription factor Ets. J. Biol. Chem. 270, 6577-6583 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 6577-6583
    • Krämer, B.1    Wiegmann, K.2    Krönke, M.3
  • 36
    • 84899478638 scopus 로고    scopus 로고
    • Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4
    • Catanzaro, J. M. et al. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4. Nat Commun 5, 3729 (2014).
    • (2014) Nat Commun , vol.5 , pp. 3729
    • Catanzaro, J.M.1
  • 37
    • 80053124740 scopus 로고    scopus 로고
    • Branched-chain amino acids, mitochondrial biogenesis, and healthspan: An evolutionary perspective
    • Albany NY
    • Valerio, A., D'Antona, G.&Nisoli, E. Branched-chain amino acids, mitochondrial biogenesis, and healthspan: An evolutionary perspective. Aging (Albany NY) 3, 464-478 (2011).
    • (2011) Aging , vol.3 , pp. 464-478
    • Valerio, A.1    D'Antona, G.2    Nisoli, E.3
  • 38
    • 33947575572 scopus 로고    scopus 로고
    • Regulation of gluconeogenesis by Krüppel-like factor 15
    • Gray, S. et al. Regulation of gluconeogenesis by Krüppel-like factor 15. Cell Metab. 5, 305-312 (2007).
    • (2007) Cell Metab , vol.5 , pp. 305-312
    • Gray, S.1
  • 39
    • 84907482179 scopus 로고    scopus 로고
    • Mutations in CIC and IDH1 cooperatively regulate 2- hydroxyglutarate levels and cell clonogenicity
    • Chittaranjan, S. et al. Mutations in CIC and IDH1 cooperatively regulate 2- hydroxyglutarate levels and cell clonogenicity. Oncotarget 5, 7960-7979 (2014).
    • (2014) Oncotarget , vol.5 , pp. 7960-7979
    • Chittaranjan, S.1
  • 40
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • Bolstad, B. M., Irizarry, R. A., Astrand, M. & Speed, T. P. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19, 185-193 (2003).
    • (2003) Bioinformatics , vol.19 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 41
    • 77950571596 scopus 로고    scopus 로고
    • Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies
    • Lee, H.-J. et al. Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies. J. Biol. Chem. 285, 9262-9272 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 9262-9272
    • Lee, H.-J.1
  • 43
    • 28444475160 scopus 로고    scopus 로고
    • A data integration methodology for systems biology
    • Hwang, D. et al. A data integration methodology for systems biology. Proc. Natl. Acad. Sci. U.S.A. 102, 17296-17301 (2005).
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 17296-17301
    • Hwang, D.1
  • 44
    • 33845657872 scopus 로고    scopus 로고
    • ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology
    • Lam, Y. C. et al. ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology. Cell 127, 1335-1347 (2006).
    • (2006) Cell , vol.127 , pp. 1335-1347
    • Lam, Y.C.1
  • 45
    • 0036190875 scopus 로고    scopus 로고
    • PROMO: Detection of known transcription regulatory elements using species-tailored searches
    • Messeguer, X. et al. PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 18, 333-334 (2002).
    • (2002) Bioinformatics , vol.18 , pp. 333-334
    • Messeguer, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.