The effect of phytic acid on tight junctions in the human intestinal Caco-2 cell line and its mechanism

European Journal of Pharmaceutical Sciences

Volumn 80, Issue , 2015, Pages 1-8

  Fu, Qingxue ^a   Wang, Huizhen ^a   Xia, Mengxin ^a   Deng, Bing ^a   Shen, Hongyi ^a   Ji, Guang ^a   Li, Guowen ^a   Xie, Yan ^a  

^a SHANGHAI UNIVERSITY   (China)

Author keywords

Divalent cations; Paracellular permeability; Phytic acid; Protein distribution; Protein expression level; Tight junction

Indexed keywords

CALCIUM ION; CLAUDIN 1; MAGNESIUM ION; OCCLUDIN; PHYTIC ACID; PROTEIN ZO1; CLDN1 PROTEIN, HUMAN; TJP1 PROTEIN, HUMAN;

ARTICLE; ATTENUATION; CACO 2 CELL LINE; CELL VIABILITY; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TIGHT JUNCTION; DOSE RESPONSE; DRUG EFFECTS; INTESTINE ABSORPTION; METABOLISM;

CACO-2 CELLS; CLAUDIN-1; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOBLOTTING; INTESTINAL ABSORPTION; MICROSCOPY, CONFOCAL; OCCLUDIN; PHYTIC ACID; TIGHT JUNCTIONS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84943371842     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.09.009     Document Type: Article

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