Sodium caprate transiently opens claudin-5-containing barriers at tight junctions of epithelial and endothelial cells

Molecular Pharmaceutics

Volumn 9, Issue 9, 2012, Pages 2523-2533

  Del Vecchio, G ^a   Tscheik, C ^a   Tenz, K ^a   Helms, H C ^b   Winkler, L ^a   Blasig, R ^a   Blasig, I E ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

actin; claudin 5; drug delivery; sodium caprate; tight junctions; tissue barrier permeability

Indexed keywords

CLAUDIN 5; DECANOATE SODIUM; F ACTIN; LUCIFER YELLOW; PROTEIN ZO1; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CHEMICAL INTERACTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; EPITHELIUM CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION; WESTERN BLOTTING;

ACTIN CYTOSKELETON; ACTINS; ANIMALS; BRAIN; CAPILLARIES; CELL LINE; CLAUDIN-5; DECANOIC ACIDS; DOGS; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HEK293 CELLS; HUMANS; ISOQUINOLINES; MADIN DARBY CANINE KIDNEY CELLS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PERMEABILITY; TIGHT JUNCTIONS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84866001368     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp3001414     Document Type: Article

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