Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα

Journal of Clinical Investigation

Volumn 125, Issue 10, 2015, Pages 3809-3818

  Bauer, Robert C ^a   Sasaki, Makoto ^a   Cohen, Daniel M ^b,c   Cui, Jian ^a   Smith, Mikhaila A ^a   Yenilmez, Batuhan O ^a   Steger, David J ^b,c   Rader, Daniel J ^a,c,d  

^a Division of Translational Medicine and Human Genetics   (United States)

^b Department of Medicine   (United States)

^c Institute for Diabetes Obesity and Metabolism   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; CCAAT ENHANCER BINDING PROTEIN ALPHA; CRE RECOMBINASE; DIACYLGLYCEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER PROTEIN; MESSENGER RNA; THYROXINE BINDING GLOBULIN; TRIACYLGLYCEROL; TRIBBLES 1; UNCLASSIFIED DRUG; CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, MOUSE; DNA; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; TRIB1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; CHOLESTEROL LIVER LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENETIC TRANSCRIPTION; LIPID LIVER LEVEL; LIPID STORAGE; LIPOGENESIS; LIPOPROTEIN METABOLISM; LIVER HYPERTROPHY; LIVER WEIGHT; LOXP SITE; MALE; MALLORY BODY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; WHITE ADIPOSE TISSUE; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIBODY SPECIFICITY; BLOOD; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; GENETICS; HYPERLIPIDEMIA; KNOCKOUT MOUSE; LIVER; METABOLISM; PHYSIOLOGY; RNA PROCESSING; TISSUE MICROARRAY; TRANSGENE; TRANSGENIC MOUSE;

ALANINE TRANSAMINASE; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; DISEASE MODELS, ANIMAL; DNA; FEMALE; HYPERLIPIDEMIAS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOGENESIS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; ORGAN SPECIFICITY; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RNA PROCESSING, POST-TRANSCRIPTIONAL; TISSUE ARRAY ANALYSIS; TRANSGENES; TRIGLYCERIDES; UP-REGULATION;

EID: 84943311798     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI77095     Document Type: Article

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