메뉴 건너뛰기




Volumn 2015, Issue 10, 2015, Pages 865-875

Animal models of chemical carcinogenesis: Driving breakthroughs in cancer research for 100 years

Author keywords

[No Author keywords available]

Indexed keywords

CROTON OIL; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYTOCHROME P450; DIETHYLNITROSAMINE; ETHYLNITROSOUREA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN P27; PROTEIN P53; URETHAN; CARCINOGEN;

EID: 84943259520     PISSN: 19403402     EISSN: 15596095     Source Type: Journal    
DOI: 10.1101/pdb.top069906     Document Type: Article
Times cited : (52)

References (106)
  • 1
    • 70249123827 scopus 로고    scopus 로고
    • Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications
    • Abel EL, Angel JM, Kiguchi K, DiGiovanni J. 2009. Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications. Nat Protoc 4: 1350-1362.
    • (2009) Nat Protoc , vol.4 , pp. 1350-1362
    • Abel, E.L.1    Angel, J.M.2    Kiguchi, K.3    DiGiovanni, J.4
  • 2
    • 4143134320 scopus 로고    scopus 로고
    • Introduction and overview. Perinatal carcinogenesis: Growing a node for epidemiology, risk management, and animal studies
    • Anderson LM. 2004. Introduction and overview. Perinatal carcinogenesis: Growing a node for epidemiology, risk management, and animal studies. Toxicol Appl Pharmacol 199: 85-90.
    • (2004) Toxicol Appl Pharmacol , vol.199 , pp. 85-90
    • Anderson, L.M.1
  • 4
    • 26044442246 scopus 로고    scopus 로고
    • Cancer in rodents: Does it tell us about cancer in humans?
    • Anisimov VN, Ukraintseva SV, Yashin AI. 2005. Cancer in rodents: Does it tell us about cancer in humans? Nat Rev Cancer 5: 807-819.
    • (2005) Nat Rev Cancer , vol.5 , pp. 807-819
    • Anisimov, V.N.1    Ukraintseva, S.V.2    Yashin, A.I.3
  • 5
    • 0034748480 scopus 로고    scopus 로고
    • Expectations for transgenic rodent cancer bioassay models
    • Ashby J. 2001. Expectations for transgenic rodent cancer bioassay models. Toxicol Pathol 29: 177-182.
    • (2001) Toxicol Pathol , vol.29 , pp. 177-182
    • Ashby, J.1
  • 6
    • 0037169357 scopus 로고    scopus 로고
    • Cancer as a complex genetic trait: Tumor susceptibility in humans and mouse models
    • Balmain A. 2002. Cancer as a complex genetic trait: Tumor susceptibility in humans and mouse models. Cell 108: 145-152.
    • (2002) Cell , vol.108 , pp. 145-152
    • Balmain, A.1
  • 7
    • 0020586334 scopus 로고
    • Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene
    • Balmain A, Pragnell IB. 1983. Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene. Nature 303: 72-74.
    • (1983) Nature , vol.303 , pp. 72-74
    • Balmain, A.1    Pragnell, I.B.2
  • 8
    • 33645736793 scopus 로고    scopus 로고
    • Genetically engineered models have advantages over xenografts for preclinical studies
    • discussion
    • Becher OJ, Holland EC. 2006. Genetically engineered models have advantages over xenografts for preclinical studies. Cancer Res 66: 3355-3358, discussion.
    • (2006) Cancer Res , vol.66 , pp. 3355-3358
    • Becher, O.J.1    Holland, E.C.2
  • 9
    • 84966175904 scopus 로고
    • A new, quantitative, approach to the study of the stages of chemical carcinogenesis in the mouse's skin
    • Berenblum I, Shubik P. 1947. A new, quantitative, approach to the study of the stages of chemical carcinogenesis in the mouse's skin. Br J Cancer 1: 383-391.
    • (1947) Br J Cancer , vol.1 , pp. 383-391
    • Berenblum, I.1    Shubik, P.2
  • 10
    • 27944437061 scopus 로고    scopus 로고
    • Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: Effects of dose, route, and diet
    • Bissahoyo A, Pearsall RS, Hanlon K, Amann V, Hicks D, Godfrey VL, Threadgill DW. 2005. Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: Effects of dose, route, and diet. Toxicol Sci 88: 340-345.
    • (2005) Toxicol Sci , vol.88 , pp. 340-345
    • Bissahoyo, A.1    Pearsall, R.S.2    Hanlon, K.3    Amann, V.4    Hicks, D.5    Godfrey, V.L.6    Threadgill, D.W.7
  • 11
    • 0014443413 scopus 로고
    • The correlation of experimental carcinogenesis and cancer in man
    • Boyland F. 1969. The correlation of experimental carcinogenesis and cancer in man. Prog Exp Tumor Res 11: 222-234.
    • (1969) Prog Exp Tumor Res , vol.11 , pp. 222-234
    • Boyland, F.1
  • 12
    • 37049045997 scopus 로고
    • Evidence for the binding of polynuclear aromatic hydrocarbons to the nucleic acids of mouse skin: Relation between carcinogenic power of hydrocarbons and their binding to deoxynucleic acid
    • Brookes P, Lawley PD. 1964. Evidence for the binding of polynuclear aromatic hydrocarbons to the nucleic acids of mouse skin: Relation between carcinogenic power of hydrocarbons and their binding to deoxynucleic acid. Nature 202: 781-784.
    • (1964) Nature , vol.202 , pp. 781-784
    • Brookes, P.1    Lawley, P.D.2
  • 13
    • 0025038030 scopus 로고
    • Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumour progression
    • Brown K, Buchmann A, Balmain A. 1990. Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumour progression. Proc Natl Acad Sci 87: 538-542.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 538-542
    • Brown, K.1    Buchmann, A.2    Balmain, A.3
  • 14
    • 0026349058 scopus 로고
    • Loss of heterozygosity and mutational alterations of the p53 gene in skin tumors of interspecific hybrid mice
    • Burns PA, Kemp CJ, Gannon JV, Lane DP, Bremner R, Balmain A. 1991. Loss of heterozygosity and mutational alterations of the p53 gene in skin tumors of interspecific hybrid mice. Oncogene 6: 2363- 2369.
    • (1991) Oncogene , vol.6 , pp. 2363-2369
    • Burns, P.A.1    Kemp, C.J.2    Gannon, J.V.3    Lane, D.P.4    Bremner, R.5    Balmain, A.6
  • 15
    • 84862023155 scopus 로고    scopus 로고
    • ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model
    • Busch SE, Gurley KE, Moser RD, Kemp CJ. 2012. ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model. J Pathol 227: 298-305.
    • (2012) J Pathol , vol.227 , pp. 298-305
    • Busch, S.E.1    Gurley, K.E.2    Moser, R.D.3    Kemp, C.J.4
  • 16
    • 84940726869 scopus 로고    scopus 로고
    • p19arf inhibits the growth and malignant progression of carcinogen induced non small cell lung cancer
    • Busch SE, Gurley KE, Moser R, Kelly-Spratt KS, Liggitt D, Kemp CJ. 2013. p19arf inhibits the growth and malignant progression of carcinogen induced non small cell lung cancer. Oncogene (in press).
    • (2013) Oncogene
    • Busch, S.E.1    Gurley, K.E.2    Moser, R.3    Kelly-Spratt, K.S.4    Liggitt, D.5    Kemp, C.J.6
  • 17
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • Chu IM, Hengst L, Slingerland JM. 2008. The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 8: 253-267.
    • (2008) Nat Rev Cancer , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 19
    • 0042881036 scopus 로고    scopus 로고
    • Cancer susceptibility in the mouse: Genetics, biology and implications for human cancer
    • Demant P. 2003. Cancer susceptibility in the mouse: Genetics, biology and implications for human cancer. Nat Rev Genet 4: 721-734.
    • (2003) Nat Rev Genet , vol.4 , pp. 721-734
    • Demant, P.1
  • 21
    • 0027363063 scopus 로고
    • Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
    • Dietrich WF, Lander ES, Smith JS, Moser AR, Gould KA, Luongo C, Borenstein N, Dove W. 1993. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 75: 631-639.
    • (1993) Cell , vol.75 , pp. 631-639
    • Dietrich, W.F.1    Lander, E.S.2    Smith, J.S.3    Moser, A.R.4    Gould, K.A.5    Luongo, C.6    Borenstein, N.7    Dove, W.8
  • 22
    • 0019829568 scopus 로고
    • The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today
    • Doll R, Peto R. 1981. The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst 66: 1191-1308.
    • (1981) J Natl Cancer Inst , vol.66 , pp. 1191-1308
    • Doll, R.1    Peto, R.2
  • 24
    • 0037732512 scopus 로고    scopus 로고
    • 10 years of mouse cancer modifier loci: Human relevance
    • Dragani TA. 2003. 10 years of mouse cancer modifier loci: Human relevance. Cancer Res 63: 3011-3018.
    • (2003) Cancer Res , vol.63 , pp. 3011-3018
    • Dragani, T.A.1
  • 28
    • 0022792772 scopus 로고
    • Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice
    • Drinkwater NR, Ginsler JJ. 1986. Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice. Carcinogenesis 7: 1701-1707.
    • (1986) Carcinogenesis , vol.7 , pp. 1701-1707
    • Drinkwater, N.R.1    Ginsler, J.J.2
  • 31
    • 0032511848 scopus 로고    scopus 로고
    • The murine gene p27Kip1 is haplo-insufficient for tumour suppression
    • Fero ML, Randel E, Gurley KE, Roberts JM, Kemp CJ. 1998. The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature 396: 177-180.
    • (1998) Nature , vol.396 , pp. 177-180
    • Fero, M.L.1    Randel, E.2    Gurley, K.E.3    Roberts, J.M.4    Kemp, C.J.5
  • 32
    • 49749166118 scopus 로고
    • Ultra-violet light and skin cancer
    • Findlay GM. 1928. Ultra-violet light and skin cancer. The Lancet ii: 1070- 1073.
    • (1928) The Lancet , vol.2 , pp. 1070-1073
    • Findlay, G.M.1
  • 33
    • 77951450917 scopus 로고    scopus 로고
    • Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate
    • Forkert PG. 2010. Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate. Drug Metab Rev 42: 355-378.
    • (2010) Drug Metab Rev , vol.42 , pp. 355-378
    • Forkert, P.G.1
  • 34
    • 34548217651 scopus 로고    scopus 로고
    • Maximizing mouse cancer models
    • Frese KK, Tuveson DA. 2007. Maximizing mouse cancer models. Nat Rev Cancer 7: 645-658.
    • (2007) Nat Rev Cancer , vol.7 , pp. 645-658
    • Frese, K.K.1    Tuveson, D.A.2
  • 35
    • 0029153806 scopus 로고
    • The carcinogenesis bioassay in perspective: Application in identifying human cancer hazards
    • Fung VA, Barrett JC, Huff J. 1995. The carcinogenesis bioassay in perspective: Application in identifying human cancer hazards. Environ Health Perspect 103: 680-683.
    • (1995) Environ Health Perspect , vol.103 , pp. 680-683
    • Fung, V.A.1    Barrett, J.C.2    Huff, J.3
  • 36
    • 2542592551 scopus 로고
    • Neoplastic diseases produced in mice by general irradiation with X-rays
    • Furth J, Furth OB. 1936. Neoplastic diseases produced in mice by general irradiation with X-rays. Am J Cancer 28: 54-65.
    • (1936) Am J Cancer , vol.28 , pp. 54-65
    • Furth, J.1    Furth, O.B.2
  • 38
    • 0014125843 scopus 로고
    • Binding of tritium-labeled polycyclic hydrocarbons to DNA of mouse skin
    • Goshman LM, Heidelberger C. 1967. Binding of tritium-labeled polycyclic hydrocarbons to DNA of mouse skin. Cancer Res 27: 1678-1688.
    • (1967) Cancer Res , vol.27 , pp. 1678-1688
    • Goshman, L.M.1    Heidelberger, C.2
  • 39
    • 84856013431 scopus 로고    scopus 로고
    • Clonal evolution in cancer
    • Greaves M, Maley CC. 2012. Clonal evolution in cancer. Nature 481: 306- 313.
    • (2012) Nature , vol.481 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2
  • 41
    • 84943247993 scopus 로고    scopus 로고
    • Induction of liver tumors in mice with N-ethyl-N-nitrosourea or N-nitrosodiethylamine
    • Gurley KE, Moser RD, Kemp CJ. 2014b. Induction of liver tumors in mice with N-ethyl-N-nitrosourea or N-nitrosodiethylamine. Cold Spring Harb Protoc doi: 10.1101/pdb.prot077438.
    • (2014) Cold Spring Harb Protoc
    • Gurley, K.E.1    Moser, R.D.2    Kemp, C.J.3
  • 42
    • 84940737950 scopus 로고    scopus 로고
    • Induction of colon cancer in mice with 1,2-dimethylhydrazine
    • Gurley KE, Moser RD, Kemp CJ. 2014c. Induction of colon cancer in mice with 1,2-dimethylhydrazine. Cold Spring Harb Protoc doi: 10.1101/pdb. prot077453.
    • (2014) Cold Spring Harb Protoc
    • Gurley, K.E.1    Moser, R.D.2    Kemp, C.J.3
  • 44
    • 33847613305 scopus 로고    scopus 로고
    • Epigenetics and cancer: Towards an evaluation of the impact of environmental and dietary factors
    • Herceg Z. 2007. Epigenetics and cancer: Towards an evaluation of the impact of environmental and dietary factors. Mutagenesis 22: 91-103.
    • (2007) Mutagenesis , vol.22 , pp. 91-103
    • Herceg, Z.1
  • 45
    • 0027175399 scopus 로고
    • Chemicals and cancer in humans: First evidence in experimental animals
    • Huff J. 1993. Chemicals and cancer in humans: First evidence in experimental animals. Environ Health Perspect 100: 201-210.
    • (1993) Environ Health Perspect , vol.100 , pp. 201-210
    • Huff, J.1
  • 46
    • 0003825978 scopus 로고
    • Scientific Publication No. 100. (ed. Tomatis L). Who Press, New York
    • IARC (International Agency for Research on Cancer). Scientific Publication No. 100. (ed. Tomatis L). Who Press, New York. 1990. Cancer: Causes, occurrence, and control.
    • (1990) Cancer: Causes, occurrence, and control
  • 50
    • 0033595088 scopus 로고    scopus 로고
    • p53 protects against skin cancer induction by UV-B radiation
    • Jiang W, Ananthaswamy HN, Muller HK, Kripke ML. 1999. p53 protects against skin cancer induction by UV-B radiation. Oncogene 18: 4247- 4253.
    • (1999) Oncogene , vol.18 , pp. 4247-4253
    • Jiang, W.1    Ananthaswamy, H.N.2    Muller, H.K.3    Kripke, M.L.4
  • 51
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • Jirtle RL, Skinner MK. 2007. Environmental epigenomics and disease susceptibility. Nat Rev Genet 8: 253-262.
    • (2007) Nat Rev Genet , vol.8 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 52
    • 19344364856 scopus 로고    scopus 로고
    • p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways
    • Kelly-Spratt KS, Gurley KE, Yasui Y, Kemp CJ. 2004. p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways. PLoS Biol 2: 1138-1149.
    • (2004) PLoS Biol , vol.2 , pp. 1138-1149
    • Kelly-Spratt, K.S.1    Gurley, K.E.2    Yasui, Y.3    Kemp, C.J.4
  • 54
    • 24944535307 scopus 로고    scopus 로고
    • Multistep skin cancer in mice as a model to study the evolvability of cancer cells
    • Kemp CJ. 2005. Multistep skin cancer in mice as a model to study the evolvability of cancer cells. Sem Cancer Biol 15: 460-473.
    • (2005) Sem Cancer Biol , vol.15 , pp. 460-473
    • Kemp, C.J.1
  • 55
    • 0028168643 scopus 로고
    • p53 deficient mice are extremely susceptible to radiation-induced tumorigenesis
    • Kemp CJ, Wheldon T, Balmain A. 1994. p53 deficient mice are extremely susceptible to radiation-induced tumorigenesis. Nat Genet 8: 66-69.
    • (1994) Nat Genet , vol.8 , pp. 66-69
    • Kemp, C.J.1    Wheldon, T.2    Balmain, A.3
  • 56
    • 0027203921 scopus 로고
    • Reduction of p53 gene dosage does not increase initiation or promotion but greatly enhances malignant progression of chemically induced skin tumors
    • Kemp CJ, Donchower LA, Bradley A, Balmain A. 1993. Reduction of p53 gene dosage does not increase initiation or promotion but greatly enhances malignant progression of chemically induced skin tumors. Cell 74: 813-822.
    • (1993) Cell , vol.74 , pp. 813-822
    • Kemp, C.J.1    Donchower, L.A.2    Bradley, A.3    Balmain, A.4
  • 57
    • 0006000333 scopus 로고
    • The identification of a carcinogenic compound in coal tar
    • Kennaway EL. 1955. The identification of a carcinogenic compound in coal tar. Br Med J ii: 749-752.
    • (1955) Br Med J , vol.2 , pp. 749-752
    • Kennaway, E.L.1
  • 58
    • 0004541482 scopus 로고
    • Researches on the carcinogenesis of the various chemical substances
    • Kinosita R. 1936. Researches on the carcinogenesis of the various chemical substances. Gann 30: 423-426.
    • (1936) Gann , vol.30 , pp. 423-426
    • Kinosita, R.1
  • 60
    • 0028073078 scopus 로고
    • Historical origins of current concepts of carcinogenesis
    • Lawley PD. 1994. Historical origins of current concepts of carcinogenesis. Adv Cancer Res 65: 17-111.
    • (1994) Adv Cancer Res , vol.65 , pp. 17-111
    • Lawley, P.D.1
  • 61
    • 13444278808 scopus 로고    scopus 로고
    • The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma
    • Lewis BC, Klimstra DS, Socci ND, Xu S, Koutcher JA, Varmus HE. 2005. The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma. Mol Cell Biol 25: 1228-1237.
    • (2005) Mol Cell Biol , vol.25 , pp. 1228-1237
    • Lewis, B.C.1    Klimstra, D.S.2    Socci, N.D.3    Xu, S.4    Koutcher, J.A.5    Varmus, H.E.6
  • 63
    • 33746556713 scopus 로고    scopus 로고
    • Candidate lung tumor susceptibility genes identified through wholegenome association analyses in inbred mice
    • Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, Liu Y, You M. 2006. Candidate lung tumor susceptibility genes identified through wholegenome association analyses in inbred mice. Nat Genet 38: 888-895.
    • (2006) Nat Genet , vol.38 , pp. 888-895
    • Liu, P.1    Wang, Y.2    Vikis, H.3    Maciag, A.4    Wang, D.5    Lu, Y.6    Liu, Y.7    You, M.8
  • 64
    • 0009723262 scopus 로고
    • Studies on the relation between tumor susceptibility and heredity. III. Spontaneous tumors of the lung in mice
    • Lynch CJ. 1926. Studies on the relation between tumor susceptibility and heredity. III. Spontaneous tumors of the lung in mice. J Exp Med 43: 339-355.
    • (1926) J Exp Med , vol.43 , pp. 339-355
    • Lynch, C.J.1
  • 65
    • 84961004853 scopus 로고
    • The production of malignant primary hepatic tumours in the rat by feeding dimethylnitrosamine
    • Magee PN, Barnes JM. 1956. The production of malignant primary hepatic tumours in the rat by feeding dimethylnitrosamine. Br J Cancer 10: 114- 122.
    • (1956) Br J Cancer , vol.10 , pp. 114-122
    • Magee, P.N.1    Barnes, J.M.2
  • 66
    • 0014176161 scopus 로고
    • Carcinogenic nitroso compounds
    • Magee PN, Barnes JM. 1967. Carcinogenic nitroso compounds. Adv Cancer Res 10: 163-246.
    • (1967) Adv Cancer Res , vol.10 , pp. 163-246
    • Magee, P.N.1    Barnes, J.M.2
  • 67
    • 0026320324 scopus 로고
    • The need for epidemiological studies of the medical exposures of Japanese patients to the carcinogenic ethyl carbamate (urethane) from 1950 to 1975
    • Miller JA. 1991. The need for epidemiological studies of the medical exposures of Japanese patients to the carcinogenic ethyl carbamate (urethane) from 1950 to 1975. Jpn J Cancer Res 82: 1323-1324.
    • (1991) Jpn J Cancer Res , vol.82 , pp. 1323-1324
    • Miller, J.A.1
  • 68
    • 0002664083 scopus 로고
    • The metabolism and carcinogenicity of p-dimethylaminoazobenzene and related compounds in the rat
    • Miller JA, Miller EC. 1947. The metabolism and carcinogenicity of p-dimethylaminoazobenzene and related compounds in the rat. Cancer Res 7: 39-41.
    • (1947) Cancer Res , vol.7 , pp. 39-41
    • Miller, J.A.1    Miller, E.C.2
  • 69
    • 0018577895 scopus 로고
    • Milestones in chemical carcinogenesis
    • Miller EC, Miller JA. 1979. Milestones in chemical carcinogenesis. Semin Oncol 6: 445-460.
    • (1979) Semin Oncol , vol.6 , pp. 445-460
    • Miller, E.C.1    Miller, J.A.2
  • 70
    • 0029086835 scopus 로고
    • Distinct genetic loci control development of benign and malignant skin tumours in mice
    • Nagase H, Bryson S, Cordell H, Kemp CJ, Fee F, Balmain A. 1995. Distinct genetic loci control development of benign and malignant skin tumours in mice. Nature Genet 10: 424-429.
    • (1995) Nature Genet , vol.10 , pp. 424-429
    • Nagase, H.1    Bryson, S.2    Cordell, H.3    Kemp, C.J.4    Fee, F.5    Balmain, A.6
  • 71
    • 80053648469 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Services Public Health Service National Toxicoloy Program
    • National Toxicology Program. 2011. 12th Report on Carcinogens. U.S. Department of Health and Human Services Public Health Service National Toxicoloy Program.
    • (2011) 12th Report on Carcinogens
  • 72
    • 84910748811 scopus 로고
    • Induction of pulmonary tumors in mice with ethyl carbamate (urethane)
    • Nettleship A, Henshaw PS, Meyer HL. 1943. Induction of pulmonary tumors in mice with ethyl carbamate (urethane). J Natl Cancer Inst 4: 309-319.
    • (1943) J Natl Cancer Inst , vol.4 , pp. 309-319
    • Nettleship, A.1    Henshaw, P.S.2    Meyer, H.L.3
  • 73
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC. 1976. The clonal evolution of tumor cell populations. Science 194: 23-28.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 74
    • 4243604626 scopus 로고
    • (ed. Office of Technology Assessment). U.S. Government Printing Office, Washington, DC
    • OTA (Office of Technology Assessment). 1981. Assessment of technologies for determining cancer risks from the environment (ed. Office of Technology Assessment). U.S. Government Printing Office, Washington, DC.
    • (1981) Assessment of technologies for determining cancer risks from the environment
  • 75
    • 0041804536 scopus 로고    scopus 로고
    • p27Kip1(Cdkn1b)-deficient mice are susceptible to chemical carcinogenesis and may be a useful model for carcinogen screening
    • Payne SR, Kemp CJ. 2003. p27Kip1(Cdkn1b)-deficient mice are susceptible to chemical carcinogenesis and may be a useful model for carcinogen screening. Toxicol Pathol 31: 355-363.
    • (2003) Toxicol Pathol , vol.31 , pp. 355-363
    • Payne, S.R.1    Kemp, C.J.2
  • 76
    • 27944490866 scopus 로고    scopus 로고
    • Tumor suppressor genetics
    • Payne SR, Kemp CJ. 2005. Tumor suppressor genetics. Carcinogenesis 26: 2031-2045.
    • (2005) Carcinogenesis , vol.26 , pp. 2031-2045
    • Payne, S.R.1    Kemp, C.J.2
  • 77
    • 0035835828 scopus 로고    scopus 로고
    • p27(Kip1): Regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer
    • Philipp-Staheli J, Payne SR, Kemp CJ. 2001. p27(Kip1): Regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer. Exp Cell Res 264: 148-168.
    • (2001) Exp Cell Res , vol.264 , pp. 148-168
    • Philipp-Staheli, J.1    Payne, S.R.2    Kemp, C.J.3
  • 78
    • 0036559462 scopus 로고    scopus 로고
    • Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice
    • Philipp-Staheli J, Kim KH, Payne SR, Gurley KE, Liggitt D, Longton G, Kemp CJ. 2002. Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice. Cancer Cell 1: 355-368.
    • (2002) Cancer Cell , vol.1 , pp. 355-368
    • Philipp-Staheli, J.1    Kim, K.H.2    Payne, S.R.3    Gurley, K.E.4    Liggitt, D.5    Longton, G.6    Kemp, C.J.7
  • 79
    • 0345213730 scopus 로고
    • Contributions to our understanding of the natural history of neoplastic development in lower animals to the cause and control of human cancer
    • Pitot HC. 1983. Contributions to our understanding of the natural history of neoplastic development in lower animals to the cause and control of human cancer. Cancer Surveys 2: 519-538.
    • (1983) Cancer Surveys , vol.2 , pp. 519-538
    • Pitot, H.C.1
  • 84
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
    • Quintanilla M, Brown K, Ramsden M, Balmain A. 1986. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 322: 78-80.
    • (1986) Nature , vol.322 , pp. 78-80
    • Quintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 85
    • 0034039895 scopus 로고    scopus 로고
    • Laboratory animal tests and human cancer
    • Rall DP. 2000. Laboratory animal tests and human cancer. Drug Metab Rev 32: 119-128.
    • (2000) Drug Metab Rev , vol.32 , pp. 119-128
    • Rall, D.P.1
  • 86
    • 0001662538 scopus 로고
    • Uberblasentumoren bei fuchsinarbeiten
    • Rehn L. 1895. Uberblasentumoren bei fuchsinarbeiten. Arch Klin Chir 50: 588.
    • (1895) Arch Klin Chir , vol.50 , pp. 588
    • Rehn, L.1
  • 87
    • 43749106257 scopus 로고    scopus 로고
    • p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis
    • Ruddell A, Kelly-Spratt KS, Furuya M, Parghi SS, Kemp CJ. 2008. p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis. Oncogene 27: 3145-3155.
    • (2008) Oncogene , vol.27 , pp. 3145-3155
    • Ruddell, A.1    Kelly-Spratt, K.S.2    Furuya, M.3    Parghi, S.S.4    Kemp, C.J.5
  • 88
    • 0001257519 scopus 로고
    • Liver carcinoma induced by feeding O-amidoazotoluene
    • Sasaki T, Yoshida T. 1935. Liver carcinoma induced by feeding O-amidoazotoluene. Arch Pathol Anat 295: 175-220.
    • (1935) Arch Pathol Anat , vol.295 , pp. 175-220
    • Sasaki, T.1    Yoshida, T.2
  • 90
    • 0022558843 scopus 로고
    • SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice
    • Slaga TJ. 1986. SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice. Environ Health Perspect 68: 27-32.
    • (1986) Environ Health Perspect , vol.68 , pp. 27-32
    • Slaga, T.J.1
  • 91
    • 0029855293 scopus 로고    scopus 로고
    • Evaluation of transgenic mouse bioassays for identifying carcinogens and noncarcinogens
    • Tennant RW, Spalding J, French JE. 1996. Evaluation of transgenic mouse bioassays for identifying carcinogens and noncarcinogens. Mutat Res 365: 119-127.
    • (1996) Mutat Res , vol.365 , pp. 119-127
    • Tennant, R.W.1    Spalding, J.2    French, J.E.3
  • 93
    • 0035802288 scopus 로고    scopus 로고
    • Complexity of lung cancer modifiers: Mapping of thirty genes and twenty-five interactions in half of the mouse genome
    • Tripodis N, Hart AA, Fijneman RJ, Demant P. 2001. Complexity of lung cancer modifiers: Mapping of thirty genes and twenty-five interactions in half of the mouse genome. J Natl Cancer Inst 93: 1484-1491.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1484-1491
    • Tripodis, N.1    Hart, A.A.2    Fijneman, R.J.3    Demant, P.4
  • 94
    • 84870845421 scopus 로고    scopus 로고
    • Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
    • Tsai JH, Donaher JL, Murphy DA, Chau S, Yang J. 2012. Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell 22: 725-736.
    • (2012) Cancer Cell , vol.22 , pp. 725-736
    • Tsai, J.H.1    Donaher, J.L.2    Murphy, D.A.3    Chau, S.4    Yang, J.5
  • 95
    • 2642605593 scopus 로고
    • Uber das kustlich erzeugte cancroid bei der maus
    • Tsutsui H. 1918. Uber das kustlich erzeugte cancroid bei der maus. Gann 12: 17-21.
    • (1918) Gann , vol.12 , pp. 17-21
    • Tsutsui, H.1
  • 96
    • 0037169361 scopus 로고    scopus 로고
    • Cancer modeling in the modern era: Progress and challenges
    • Van Dyke T, Jacks T. 2002. Cancer modeling in the modern era: Progress and challenges. Cell 108: 135-144.
    • (2002) Cell , vol.108 , pp. 135-144
    • Van Dyke, T.1    Jacks, T.2
  • 98
    • 0032541321 scopus 로고    scopus 로고
    • Retention of wild-type 53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation
    • Venkatachalam S, Shi YP, Jones SN, Vogel H, Bradley A, Pinkel D, Donehower LA. 1998. Retention of wild-type 53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation. EMBO J 17: 4657-4667.
    • (1998) EMBO J , vol.17 , pp. 4657-4667
    • Venkatachalam, S.1    Shi, Y.P.2    Jones, S.N.3    Vogel, H.4    Bradley, A.5    Pinkel, D.6    Donehower, L.A.7
  • 99
    • 0019121552 scopus 로고
    • Effects of dose and duration of treatment with the tumour promoting agent, 12-O-tetradecanoylphorbol-13- acetate
    • Verma AK, Boutwell RK. 1980. Effects of dose and duration of treatment with the tumour promoting agent, 12-O-tetradecanoylphorbol-13- acetate. Carcinogenesis 1: 271-276.
    • (1980) Carcinogenesis , vol.1 , pp. 271-276
    • Verma, A.K.1    Boutwell, R.K.2
  • 101
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW. 2004. Cancer genes and the pathways they control. Nat Med 10: 789-799.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 102
    • 0000567484 scopus 로고
    • Chemistry, carcinogenicity, and metabolism of 2-fluorenamine and related compounds
    • Weisberger EK, Weisburger JH. 1958. Chemistry, carcinogenicity, and metabolism of 2-fluorenamine and related compounds. Adv Cancer Res 5: 331-431.
    • (1958) Adv Cancer Res , vol.5 , pp. 331-431
    • Weisberger, E.K.1    Weisburger, J.H.2
  • 103
    • 0019792758 scopus 로고
    • Carcinogen testing: Current problems and new approaches
    • Weisburger JH, Williams GM. 1981. Carcinogen testing: Current problems and new approaches. Science 214: 401-407.
    • (1981) Science , vol.214 , pp. 401-407
    • Weisburger, J.H.1    Williams, G.M.2
  • 104
    • 0003139306 scopus 로고
    • Experimental study of the pathogenesis of carcinoma
    • Yamagiwa K, Ichikawa K. 1918. Experimental study of the pathogenesis of carcinoma. J Cancer Res 3: 1-29.
    • (1918) J Cancer Res , vol.3 , pp. 1-29
    • Yamagiwa, K.1    Ichikawa, K.2
  • 105
    • 0021871265 scopus 로고
    • Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats
    • Zarbl H, Sukumar S, Arthur AV, Martin-Zanca D, Barbacid M. 1985. Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats. Nature 315: 382-385.
    • (1985) Nature , vol.315 , pp. 382-385
    • Zarbl, H.1    Sukumar, S.2    Arthur, A.V.3    Martin-Zanca, D.4    Barbacid, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.