Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate

Drug Metabolism Reviews

Volumn 42, Issue 2, 2010, Pages 355-378

  Forkert, Poh Gek ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Big Blue mice; Carboxylesterase; CYP2E1; Diallyl sulfone; Epoxide; Ethyl carbamate; Kras2; Lung; Mutations; Vinyl carbamate

Indexed keywords

1,N4 ETHENODEOXYCYTIDINE; 1,N6 ETHENODEOXYADENOSINE; CARBAMIC ACID DERIVATIVE; CARBAMIC ACID VINYL ESTER; CARBOXYLESTERASE; CYTIDINE DERIVATIVE; CYTOCHROME P450 2E1; CYTOCHROME P450 INHIBITOR; DEOXYADENOSINE DERIVATIVE; DIALLYL SULFONE; DNA; EPOXIDE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MONOCLONAL ANTIBODY; N METHYL DEXTRO ASPARTIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG; URETHAN;

A J MOUSE; C57BL 6 MOUSE; DNA ADDUCT; DNA BINDING; DOSE RESPONSE; DRUG MECHANISM; FRAMESHIFT MUTATION; HUMAN; K RAS 2 ONCOGENE; LAMBDA CII TRANSGENE; LUNG CARCINOGENESIS; LUNG CARCINOMA; METABOLISM; MICROSOME; MUTATION RATE; NONHUMAN; ONCOGENE K RAS; OXIDATION; POINT MUTATION; REVIEW; TRANSGENE; TRANSGENIC MOUSE;

ALLYL COMPOUNDS; ANIMALS; CARCINOGENS, ENVIRONMENTAL; DNA ADDUCTS; HUMANS; LUNG NEOPLASMS; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, TRANSGENIC; MUTATION; SULFONES; URETHANE;

EID: 77951450917     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602531003611915     Document Type: Review

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