Enhanced oxidative stress sensitizes the mitochondrial permeability transition pore to opening in heart from Zucker Fa/fa rats with type 2 diabetes

Life Sciences

Volumn 141, Issue , 2015, Pages 32-43

  Riojas Hernández, Adriana ^a   Bernal Ramírez, Judith ^a   Rodríguez Mier, David ^a   Morales Marroquín, Flor E ^a   Domínguez Barragán, Elvia M ^a   Borja Villa, Cuauhtémoc ^a   Rivera Álvarez, Irais ^a   García Rivas, Gerardo ^a,b   Altamirano, Julio ^a,b   García, Noemí ^a,b  

^a SCHOOL OF ENGINEERING AND SCIENCES   (Mexico)

^b HOSPITAL ZAMBRANO HELLION   (Mexico)

Author keywords

Calcium; Cardiovascular disease; Diastolic dysfunction; Mitochondrial dysfunction; Obesity

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; ADENINE NUCLEOTIDE TRANSLOCASE; ATRACTYLOSIDE; CARBOXYATRACTYLOSIDE; CARRIER PROTEIN; LEPTIN; LIPID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ENZYME ACTIVITY; HEART DISEASE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MITOCHONDRION; HEART MUSCLE CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; RAT; ZUCKER FATTY RAT; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; COMPLICATION; ECHOGRAPHY; HEART DISEASES; METABOLISM; OXYGEN CONSUMPTION; PATHOLOGY; PATHOPHYSIOLOGY; PERMEABILITY; ZUCKER RAT;

ANIMALS; ATRACTYLOSIDE; CALCIUM SIGNALING; DIABETES MELLITUS, TYPE 2; HEART DISEASES; LEPTIN; LIPIDS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCYTES, CARDIAC; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PERMEABILITY; RATS; RATS, ZUCKER;

EID: 84943148758     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.09.018     Document Type: Article

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