Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 292, Issue 2, 2007, Pages

  Katakam, Prasad V G ^a   Jordan, James E ^a   Snipes, James A ^a   Tulbert, Christina D ^a   Miller, Allison W ^a   Busija, David W ^a  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

Mitochondrial KATP; Obesity; Type 2 diabetes

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE; DIAZOXIDE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL PROTEIN; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON MICROSCOPY; HEART DEPOLARIZATION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMMUNOBLOTTING; INSULIN RESISTANCE; ISCHEMIC PRECONDITIONING; MALE; MITOCHONDRION; MITOCHONDRION SWELLING; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; ZUCKER RAT;

ANIMALS; DECANOIC ACIDS; DIAZOXIDE; HYDROXY ACIDS; IMMUNOBLOTTING; INSULIN RESISTANCE; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MEMBRANE POTENTIALS; MICROSCOPY, ELECTRON; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANES; MYOCARDIAL REPERFUSION INJURY; OBESITY; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, ZUCKER; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE; VASODILATOR AGENTS;

EID: 33846815373     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00520.2006     Document Type: Article

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