Oxidative stress in cardiomyocytes contributes to decreased SERCA2a activity in rats with metabolic syndrome

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 9, 2013, Pages

  Balderas Villalobos, Jaime ^a,b   Molina Muñoz, Tzindilu ^a   Mailloux Salinas, Patrick ^a   Bravo, Guadalupe ^a   Carvajal, Karla ^b   Gómez Viquez, Norma L ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

Author keywords

Calcium; Heart; Metabolic syndrome; Oxidative stress; Sarco(endo)plasmic reticulum Ca2+ ATPase 2a

Indexed keywords

ACETYLCYSTEINE; CALCIUM; INSULIN; IODOACETAMIDE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARDIOMYOPATHY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; HOMOGENATE; HYPOTHESIS; INSULIN RESISTANCE; LEFT VENTRICULAR DIASTOLIC DYSFUNCTION; MALE; METABOLIC DISORDER; METABOLIC SYNDROME X; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

CALCIUM; HEART; METABOLIC SYNDROME; OXIDATIVE STRESS; SARCO(ENDO)PLASMIC RETICULUM CA2+-ATPASE 2A;

ANIMALS; ANTIOXIDANTS; CALCIUM; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; DIETARY SUCROSE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HYPERINSULINISM; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; MALE; METABOLIC SYNDROME X; MYOCYTES, CARDIAC; OBESITY, ABDOMINAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHOSPHORYLATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84887049181     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00211.2013     Document Type: Article

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