메뉴 건너뛰기




Volumn 26, Issue 10, 2015, Pages 2423-2433

NH4Cl treatment prevents tissue calcification in klotho deficiency

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ALKALINE PHOSPHATASE; AMMONIUM CHLORIDE; CALCITRIOL; CALCIUM; DRINKING WATER; KLOTHO PROTEIN; MESSENGER RNA; PHOSPHATE; PROTEIN P21; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFAT5; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASOPRESSIN; BETA GLUCURONIDASE;

EID: 84942920514     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2014030230     Document Type: Article
Times cited : (54)

References (81)
  • 1
    • 84890807103 scopus 로고    scopus 로고
    • Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism
    • Kuroo M: Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism. Nat Rev Nephrol 9: 650-660, 2013.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 650-660
    • Kuroo, M.1
  • 2
    • 34250636801 scopus 로고    scopus 로고
    • Regulation of the epithelial calcium channel TRPV5 by extracellular factors
    • Topala CN, Bindels RJ, Hoenderop JG: Regulation of the epithelial calcium channel TRPV5 by extracellular factors. Curr Opin Nephrol Hypertens 16: 319-324, 2007.
    • (2007) Curr Opin Nephrol Hypertens , vol.16 , pp. 319-324
    • Topala, C.N.1    Bindels, R.J.2    Hoenderop, J.G.3
  • 7
    • 73449102873 scopus 로고    scopus 로고
    • The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect
    • Invidia L, Salvioli S, Altilia S, Pierini M, Panourgia MP, Monti D, De-Rango F, Passarino G, Franceschi C: The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect. Biogerontology 11: 67-73, 2010.
    • (2010) Biogerontology , vol.11 , pp. 67-73
    • Invidia, L.1    Salvioli, S.2    Altilia, S.3    Pierini, M.4    Panourgia, M.P.5    Monti, D.6    De-Rango, F.7    Passarino, G.8    Franceschi, C.9
  • 8
    • 84873350580 scopus 로고    scopus 로고
    • Mechanistic insights into vascular calcification in CKD
    • Shroff R, Long DA, Shanahan C: Mechanistic insights into vascular calcification in CKD. J Am Soc Nephrol 24: 179-189, 2013.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 179-189
    • Shroff, R.1    Long, D.A.2    Shanahan, C.3
  • 9
    • 84875657698 scopus 로고    scopus 로고
    • Cardiovascular risk and mineral bone disorder in patients with chronic kidney disease
    • Staude H, Jeske S, Schmitz K, Warncke G, Fischer DC: Cardiovascular risk and mineral bone disorder in patients with chronic kidney disease. Kidney Blood Press Res 37: 68-83, 2013.
    • (2013) Kidney Blood Press Res , vol.37 , pp. 68-83
    • Staude, H.1    Jeske, S.2    Schmitz, K.3    Warncke, G.4    Fischer, D.C.5
  • 10
    • 84864398735 scopus 로고    scopus 로고
    • The emerging role of Klotho in clinical nephrology
    • Hu MC, Kuroo M, Moe OW: The emerging role of Klotho in clinical nephrology. Nephrol Dial Transplant 27: 2650-2657, 2012.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 2650-2657
    • Hu, M.C.1    Kuroo, M.2    Moe, O.W.3
  • 12
    • 67649678424 scopus 로고    scopus 로고
    • Vascular calcification: The killer of patients with chronic kidney disease
    • Mizobuchi M, Towler D, Slatopolsky E: Vascular calcification: The killer of patients with chronic kidney disease. J Am Soc Nephrol 20: 1453- 1464, 2009.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1453-1464
    • Mizobuchi, M.1    Towler, D.2    Slatopolsky, E.3
  • 13
    • 0035824898 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers
    • Steitz SA, Speer MY, Curinga G, Yang HY, Haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM: Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers. Circ Res 89: 1147- 1154, 2001.
    • (2001) Circ Res , vol.89 , pp. 1147-1154
    • Steitz, S.A.1    Speer, M.Y.2    Curinga, G.3    Yang, H.Y.4    Haynes, P.5    Aebersold, R.6    Schinke, T.7    Karsenty, G.8    Giachelli, C.M.9
  • 14
    • 0043037220 scopus 로고    scopus 로고
    • Vascular calcification: In vitro evidence for the role of inorganic phosphate
    • Giachelli CM: Vascular calcification: In vitro evidence for the role of inorganic phosphate. J AmSocNephrol 14[Suppl 4]: S300-S304, 2003.
    • (2003) J AmSocNephrol , vol.14 , pp. S300-S304
    • Giachelli, C.M.1
  • 15
    • 4644231530 scopus 로고    scopus 로고
    • Pathophysiology of vascular calcification in chronic kidney disease
    • Moe SM, Chen NX: Pathophysiology of vascular calcification in chronic kidney disease. Circ Res 95: 560-567, 2004.
    • (2004) Circ Res , vol.95 , pp. 560-567
    • Moe, S.M.1    Chen, N.X.2
  • 18
    • 84865539985 scopus 로고    scopus 로고
    • Transcription factor Runx2 and its application to bone tissue engineering
    • Dalle-Carbonare L, Innamorati G, Valenti MT: Transcription factor Runx2 and its application to bone tissue engineering. Stem Cell Rev 8: 891-897, 2012.
    • (2012) Stem Cell Rev , vol.8 , pp. 891-897
    • Dalle-Carbonare, L.1    Innamorati, G.2    Valenti, M.T.3
  • 19
    • 77954083762 scopus 로고    scopus 로고
    • Molecular determinants of extracellular matrix mineralization in bone and blood vessels
    • Murshed M, McKee MD:Molecular determinants of extracellular matrix mineralization in bone and blood vessels. Curr Opin Nephrol Hypertens 19: 359-365, 2010.
    • (2010) Curr Opin Nephrol Hypertens , vol.19 , pp. 359-365
    • Murshed, M.1    McKee, M.D.2
  • 21
    • 79954992400 scopus 로고    scopus 로고
    • The role of cellular senescence during vascular calcification: A key paradigmin aging research
    • Mackenzie NC, MacRae VE: The role of cellular senescence during vascular calcification: A key paradigmin aging research. Curr Aging Sci 4: 128-136, 2011.
    • (2011) Curr Aging Sci , vol.4 , pp. 128-136
    • Mackenzie, N.C.1    MacRae, V.E.2
  • 23
    • 40149102029 scopus 로고    scopus 로고
    • Klotho as a regulator of oxidative stress and senescence
    • Kuroo M: Klotho as a regulator of oxidative stress and senescence. Biol Chem 389: 233-241, 2008.
    • (2008) Biol Chem , vol.389 , pp. 233-241
    • Kuroo, M.1
  • 26
    • 84864614160 scopus 로고    scopus 로고
    • Metabolic acidosis and kidney disease: Does bicarbonate therapy slow the progression of CKD?
    • Kovesdy CP: Metabolic acidosis and kidney disease: Does bicarbonate therapy slow the progression of CKD? Nephrol Dial Transplant 27: 3056-3062, 2012.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 3056-3062
    • Kovesdy, C.P.1
  • 27
    • 68049148648 scopus 로고    scopus 로고
    • Vascular calcification and metabolic acidosis in end stage renal disease
    • Yonova D: Vascular calcification and metabolic acidosis in end stage renal disease. Hippokratia 13: 139-140, 2009.
    • (2009) Hippokratia , vol.13 , pp. 139-140
    • Yonova, D.1
  • 29
    • 77949885535 scopus 로고    scopus 로고
    • Compensatory regulation of the sodium/phosphate cotransporters NaPi-IIc (SCL34A3) and Pit-2 (SLC20A2) during Pi deprivation and acidosis
    • Villa-Bellosta R, Sorribas V: Compensatory regulation of the sodium/phosphate cotransporters NaPi-IIc (SCL34A3) and Pit-2 (SLC20A2) during Pi deprivation and acidosis. Pflugers Arch 459: 499-508, 2010.
    • (2010) Pflugers Arch , vol.459 , pp. 499-508
    • Villa-Bellosta, R.1    Sorribas, V.2
  • 30
    • 64549093430 scopus 로고    scopus 로고
    • Regulation of phosphate transport in proximal tubules
    • Biber J, Hernando N, Forster I, Murer H: Regulation of phosphate transport in proximal tubules. Pflugers Arch 458: 39-52, 2009.
    • (2009) Pflugers Arch , vol.458 , pp. 39-52
    • Biber, J.1    Hernando, N.2    Forster, I.3    Murer, H.4
  • 32
    • 0033857091 scopus 로고    scopus 로고
    • Chronic metabolic acidosis in azotemic rats on a high-phosphate diet halts the progression of renal disease
    • Jara A, Felsenfeld AJ, Bover J, Kleeman CR: Chronic metabolic acidosis in azotemic rats on a high-phosphate diet halts the progression of renal disease. Kidney Int 58: 1023-1032, 2000.
    • (2000) Kidney Int , vol.58 , pp. 1023-1032
    • Jara, A.1    Felsenfeld, A.J.2    Bover, J.3    Kleeman, C.R.4
  • 33
    • 4344661999 scopus 로고    scopus 로고
    • Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. I. Renal function and biochemical changes
    • Jara A, Chacón C, IbacetaM, Valdivieso A, Felsenfeld AJ: Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. I. Renal function and biochemical changes. Nephrol Dial Transplant 19: 1986-1992, 2004.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 1986-1992
    • Jara, A.1    Chacón, C.2    Ibaceta, M.3    Valdivieso, A.4    Felsenfeld, A.J.5
  • 34
    • 84895079730 scopus 로고    scopus 로고
    • Bicarbonate therapy for prevention of chronic kidney disease progression
    • Łoniewski I, Wesson DE: Bicarbonate therapy for prevention of chronic kidney disease progression. Kidney Int 85: 529-535, 2014.
    • (2014) Kidney Int , vol.85 , pp. 529-535
    • Łoniewski, I.1    Wesson, D.E.2
  • 35
    • 0021886145 scopus 로고
    • Pathophysiology of chronic tubulointerstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3
    • Nath KA, HostetterMK, HostetterT H: Pathophysiology of chronic tubulointerstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3. J Clin Invest 76: 667-675, 1985.
    • (1985) J Clin Invest , vol.76 , pp. 667-675
    • Nath, K.A.1    Hostetter, M.K.2    HostetterT, H.3
  • 36
    • 37549007188 scopus 로고    scopus 로고
    • Dietary protein causes a decline in the glomerular filtration rate of the remnant kidney mediated by metabolic acidosis and endothelin receptors
    • Phisitkul S, Hacker C, Simoni J, Tran RM, Wesson DE: Dietary protein causes a decline in the glomerular filtration rate of the remnant kidney mediated by metabolic acidosis and endothelin receptors. Kidney Int 73: 192-199, 2008.
    • (2008) Kidney Int , vol.73 , pp. 192-199
    • Phisitkul, S.1    Hacker, C.2    Simoni, J.3    Tran, R.M.4    Wesson, D.E.5
  • 37
    • 84869208407 scopus 로고    scopus 로고
    • Angiotensin II receptors mediate increased distal nephron acidification caused by acid retention
    • Wesson DE, Jo CH, Simoni J: Angiotensin II receptors mediate increased distal nephron acidification caused by acid retention. Kidney Int 82: 1184-1194, 2012.
    • (2012) Kidney Int , vol.82 , pp. 1184-1194
    • Wesson, D.E.1    Jo, C.H.2    Simoni, J.3
  • 39
    • 84924047041 scopus 로고    scopus 로고
    • Current status of bicarbonate in CKD
    • published online ahead of print August 22
    • Dobre M, Rahman M, Hostetter TH: Current status of bicarbonate in CKD [published online ahead of print August 22, 2014]. J Am Soc Nephrol doi:10.1681/ASN.2014020205.
    • (2014) J Am Soc Nephrol
    • Dobre, M.1    Rahman, M.2    Hostetter, T.H.3
  • 40
    • 78651262030 scopus 로고    scopus 로고
    • Induction of metabolic acidosis with ammoniumchloride (NH4Cl) in mice and rats- species differences and technical considerations
    • Nowik M, Kampik NB, Mihailova M, Eladari D, Wagner CA: Induction of metabolic acidosis with ammoniumchloride (NH4Cl) in mice and rats- species differences and technical considerations. Cell Physiol Biochem 26: 1059-1072, 2010.
    • (2010) Cell Physiol Biochem , vol.26 , pp. 1059-1072
    • Nowik, M.1    Kampik, N.B.2    Mihailova, M.3    Eladari, D.4    Wagner, C.A.5
  • 41
    • 84873114039 scopus 로고    scopus 로고
    • Regulation of two renal chloride transporters, AE1 and pendrin, by electrolytes and aldosterone
    • Mohebbi N, Perna A, van der Wijst J, Becker HM, Capasso G, Wagner CA: Regulation of two renal chloride transporters, AE1 and pendrin, by electrolytes and aldosterone. PLoS ONE 8: e55286, 2013.
    • (2013) PLoS ONE , vol.8 , pp. e55286
    • Mohebbi, N.1    Perna, A.2    Van Der Wijst, J.3    Becker, H.M.4    Capasso, G.5    Wagner, C.A.6
  • 42
    • 0019554835 scopus 로고
    • Intracellular pH
    • Roos A, Boron WF: Intracellular pH. Physiol Rev 61: 296-434, 1981.
    • (1981) Physiol Rev , vol.61 , pp. 296-434
    • Roos, A.1    Boron, W.F.2
  • 43
    • 0031748929 scopus 로고    scopus 로고
    • Mesangial cell hypertrophy induced by NH4Cl: Role of depressed activities of cathepsins due to elevated lysosomal pH
    • Ling H, Ardjomand P, Samvakas S, Simm A, Busch GL, Lang F, Sebekova K, Heidland A: Mesangial cell hypertrophy induced by NH4Cl: Role of depressed activities of cathepsins due to elevated lysosomal pH. Kidney Int 53: 1706-1712, 1998.
    • (1998) Kidney Int , vol.53 , pp. 1706-1712
    • Ling, H.1    Ardjomand, P.2    Samvakas, S.3    Simm, A.4    Busch, G.L.5    Lang, F.6    Sebekova, K.7    Heidland, A.8
  • 44
    • 0027495032 scopus 로고
    • Effect of cell volume on Acridine Orange fluorescence in hepatocytes
    • Völkl H, Friedrich F, Häussinger D, Lang F: Effect of cell volume on Acridine Orange fluorescence in hepatocytes. Biochem J 295: 11-14, 1993.
    • (1993) Biochem J , vol.295 , pp. 11-14
    • Völkl, H.1    Friedrich, F.2    Häussinger, D.3    Lang, F.4
  • 45
    • 73849102776 scopus 로고    scopus 로고
    • Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity
    • Häussinger D, Görg B: Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity. Curr Opin ClinNutr Metab Care 13: 87- 92, 2010.
    • (2010) Curr Opin ClinNutr Metab Care , vol.13 , pp. 87-92
    • Häussinger, D.1    Görg, B.2
  • 46
    • 77954142513 scopus 로고    scopus 로고
    • The Na-K-Cl Co-transporter in astrocyte swelling
    • Jayakumar AR, Norenberg MD: The Na-K-Cl Co-transporter in astrocyte swelling. Metab Brain Dis 25: 31-38, 2010.
    • (2010) Metab Brain Dis , vol.25 , pp. 31-38
    • Jayakumar, A.R.1    Norenberg, M.D.2
  • 47
    • 84871409681 scopus 로고    scopus 로고
    • Transporters and channels in cytotoxic astrocyte swelling
    • Pasantes-Morales H, Vázquez-Juárez E: Transporters and channels in cytotoxic astrocyte swelling. Neurochem Res 37: 2379-2387, 2012.
    • (2012) Neurochem Res , vol.37 , pp. 2379-2387
    • Pasantes-Morales, H.1    Vázquez-Juárez, E.2
  • 48
    • 0035106793 scopus 로고    scopus 로고
    • Cell and molecular biology of organic osmolyte accumulation in hypertonic renal cells
    • Handler JS, Kwon HM: Cell and molecular biology of organic osmolyte accumulation in hypertonic renal cells. Nephron 87: 106-110, 2001.
    • (2001) Nephron , vol.87 , pp. 106-110
    • Handler, J.S.1    Kwon, H.M.2
  • 49
  • 50
    • 84871645961 scopus 로고    scopus 로고
    • Osmolarity determines the in vitro chondrogenic differentiation capacity of progenitor cells via nuclear factor of activated T-cells 5
    • Caron MM, van der Windt AE, Emans PJ, van Rhijn LW, Jahr H, Welting TJ: Osmolarity determines the in vitro chondrogenic differentiation capacity of progenitor cells via nuclear factor of activated T-cells 5. Bone 53: 94-102, 2013.
    • (2013) Bone , vol.53 , pp. 94-102
    • Caron, M.M.1    Van Der Windt, A.E.2    Emans, P.J.3    Van Rhijn, L.W.4    Jahr, H.5    Welting, T.J.6
  • 51
    • 50849130582 scopus 로고    scopus 로고
    • Lysosomotropic drugs inhibit maturation of transforming growth factor-beta
    • Basque J, Marte lM, Leduc R, Cantin AM: Lysosomotropic drugs inhibit maturation of transforming growth factor-beta. Can J Physiol Pharmacol 86: 606-612, 2008.
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 606-612
    • Basque, J.1    Marte, L.2    Leduc, R.3    Cantin, A.M.4
  • 52
    • 77953483355 scopus 로고    scopus 로고
    • BMP-2 and TGF-beta stimulate expression of beta1, 3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: Role of MAPKs
    • Hiyama A, Gogate SS, Gajghate S, Mochida J, Shapiro IM, Risbud MV: BMP-2 and TGF-beta stimulate expression of beta1, 3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: Role of MAPKs. J Bone Miner Res 25: 1179-1190, 2010.
    • (2010) J Bone Miner Res , vol.25 , pp. 1179-1190
    • Hiyama, A.1    Gogate, S.S.2    Gajghate, S.3    Mochida, J.4    Shapiro, I.M.5    Risbud, M.V.6
  • 53
    • 79953690508 scopus 로고    scopus 로고
    • Pleiotropic effects of transforming growth factor-b1 on pericardial interstitial cells Implications for fibrosis and calcification in idiopathic constrictive pericarditis
    • Liu X, Bai C, Gong D, Yuan Y, Han L, Lu F, Han Q, Tang H, Huang S, Xu Z: Pleiotropic effects of transforming growth factor-b1 on pericardial interstitial cells. Implications for fibrosis and calcification in idiopathic constrictive pericarditis. J Am Coll Cardiol 57: 1634-1635, 2011.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 1634-1635
    • Liu, X.1    Bai, C.2    Gong, D.3    Yuan, Y.4    Han, L.5    Lu, F.6    Han, Q.7    Tang, H.8    Huang, S.9    Xu, Z.10
  • 54
    • 77957884403 scopus 로고    scopus 로고
    • Matrix remodeling in vascular calcification associated with chronic kidney disease
    • Pai AS, Giachelli CM: Matrix remodeling in vascular calcification associated with chronic kidney disease. J Am Soc Nephrol 21: 1637-1640, 2010.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1637-1640
    • Pai, A.S.1    Giachelli, C.M.2
  • 56
    • 84893162772 scopus 로고    scopus 로고
    • Atorvastatin protects vascular smooth muscle cells from TGF-b1- stimulated calcification by inducing autophagy via suppression of the b-catenin pathway
    • Liu D, Cui W, Liu B, Hu H, Liu J, Xie R, Yang X, Gu G, Zhang J, Zheng H: Atorvastatin protects vascular smooth muscle cells from TGF-b1- stimulated calcification by inducing autophagy via suppression of the b-catenin pathway. Cell Physiol Biochem 33: 129-141, 2014.
    • (2014) Cell Physiol Biochem , vol.33 , pp. 129-141
    • Liu, D.1    Cui, W.2    Liu, B.3    Hu, H.4    Liu, J.5    Xie, R.6    Yang, X.7    Gu, G.8    Zhang, J.9    Zheng, H.10
  • 57
    • 62249090222 scopus 로고    scopus 로고
    • Targeting vascular calcification: Softeningup a hard target
    • Kapustin A, Shanahan CM: Targeting vascular calcification: Softeningup a hard target. Curr Opin Pharmacol 9: 84-89, 2009.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 84-89
    • Kapustin, A.1    Shanahan, C.M.2
  • 58
    • 76149097543 scopus 로고    scopus 로고
    • Calcium metabolism in health and disease
    • Peacock M: Calcium metabolism in health and disease. Clin J Am Soc Nephrol 5[Suppl 1]: S23-S30, 2010.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. S23-S30
    • Peacock, M.1
  • 59
    • 53849083453 scopus 로고    scopus 로고
    • Mechanisms of arterial calcification: Spotlight on the inhibitors
    • Weissen-Plenz G, Nitschke Y, Rutsch F: Mechanisms of arterial calcification: Spotlight on the inhibitors. Adv Clin Chem 46: 263-293, 2008.
    • (2008) Adv Clin Chem , vol.46 , pp. 263-293
    • Weissen-Plenz, G.1    Nitschke, Y.2    Rutsch, F.3
  • 60
    • 27444436252 scopus 로고    scopus 로고
    • Cholesterol and recurrent events trial investigators: Relation between serum phosphate level and cardiovascular event rate in people with coronary disease
    • Tonelli M, Sacks F, Pfeffer M, Gao Z, Curhan G; Cholesterol and Recurrent Events Trial Investigators: Relation between serum phosphate level and cardiovascular event rate in people with coronary disease. Circulation 112: 2627-2633, 2005.
    • (2005) Circulation , vol.112 , pp. 2627-2633
    • Tonelli, M.1    Sacks, F.2    Pfeffer, M.3    Gao, Z.4    Curhan, G.5
  • 61
    • 0000327807 scopus 로고
    • PH regulation in single glomerular mesangial cells. I. Acid extrusion in absen ce and presence of HCO3
    • Boyarsky G, Ganz MB, Sterzel RB, Boron WF: pH regulation in single glomerular mesangial cells. I. Acid extrusion in absen ce and presence of HCO3. Am J Physiol 255: C844-C856, 1988.
    • (1988) Am J Physiol , vol.255 , pp. C844-C856
    • Boyarsky, G.1    Ganz, M.B.2    Sterzel, R.B.3    Boron, W.F.4
  • 62
    • 59649091992 scopus 로고    scopus 로고
    • In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23)-mediated regulation of systemic phosphate homeostasis
    • Nakatani T, Sarraj B, Ohnishi M, Densmore MJ, Taguchi T, Goetz R, Mohammadi M, Lanske B, Razzaque MS: In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23)-mediated regulation of systemic phosphate homeostasis. FASEB J 23: 433-441, 2009.
    • (2009) FASEB J , vol.23 , pp. 433-441
    • Nakatani, T.1    Sarraj, B.2    Ohnishi, M.3    Densmore, M.J.4    Taguchi, T.5    Goetz, R.6    Mohammadi, M.7    Lanske, B.8    Razzaque, M.S.9
  • 63
    • 84872954260 scopus 로고    scopus 로고
    • Nuclearmatrix-targeting of the osteogenic factor Runx2 is essential for its recognition and activation of the alkaline phosphatase gene
    • Weng JJ, Su Y: Nuclearmatrix-targeting of the osteogenic factor Runx2 is essential for its recognition and activation of the alkaline phosphatase gene. Biochim Biophys Acta 1830: 2839-2852, 2013.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 2839-2852
    • Weng, J.J.1    Su, Y.2
  • 64
    • 84863667325 scopus 로고    scopus 로고
    • Aging and atherosclerosis: Mechanisms, functional consequences, and potential therapeutics for cellular senescence
    • Wang JC, Bennett M: Aging and atherosclerosis: Mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circ Res 111: 245-259, 2012.
    • (2012) Circ Res , vol.111 , pp. 245-259
    • Wang, J.C.1    Bennett, M.2
  • 67
    • 38849207866 scopus 로고    scopus 로고
    • Nitric oxide regulates vascular calcification by interfering with TGF- signalling
    • Kanno Y, Into T, Lowenstein CJ, Matsushita K: Nitric oxide regulates vascular calcification by interfering with TGF- signalling. Cardiovasc Res 77: 221-230, 2008.
    • (2008) Cardiovasc Res , vol.77 , pp. 221-230
    • Kanno, Y.1    Into, T.2    Lowenstein, C.J.3    Matsushita, K.4
  • 68
    • 84861709581 scopus 로고    scopus 로고
    • SOX9 and myocardin counteract each other in regulating vascular smooth muscle cell differentiation
    • Xu Z, Ji G, Shen J, Wang X, Zhou J, Li L: SOX9 and myocardin counteract each other in regulating vascular smooth muscle cell differentiation. Biochem Biophys Res Commun 422: 285-290, 2012.
    • (2012) Biochem Biophys Res Commun , vol.422 , pp. 285-290
    • Xu, Z.1    Ji, G.2    Shen, J.3    Wang, X.4    Zhou, J.5    Li, L.6
  • 69
  • 71
  • 72
    • 0032229826 scopus 로고    scopus 로고
    • Epidemiology of cardiovascular disease in chronic renal disease
    • Foley RN, Parfrey PS, Sarnak MJ: Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol 9[Suppl]: S16-S23, 1998.
    • (1998) J Am Soc Nephrol , vol.9 , pp. S16-S23
    • Foley, R.N.1    Parfrey, P.S.2    Sarnak, M.J.3
  • 74
    • 84892921362 scopus 로고    scopus 로고
    • Treatment of metabolic acidosis in patients with CKD
    • Chen W, Abramowitz MK: Treatment of metabolic acidosis in patients with CKD. Am J Kidney Dis 63: 311-317, 2014.
    • (2014) Am J Kidney Dis , vol.63 , pp. 311-317
    • Chen, W.1    Abramowitz, M.K.2
  • 75
    • 84873550424 scopus 로고    scopus 로고
    • Does correction of metabolic acidosis slow chronic kidney disease progression?
    • Goraya N, Wesson DE: Does correction of metabolic acidosis slow chronic kidney disease progression? Curr Opin Nephrol Hypertens 22: 193-197, 2013.
    • (2013) Curr Opin Nephrol Hypertens , vol.22 , pp. 193-197
    • Goraya, N.1    Wesson, D.E.2
  • 78
    • 84866456641 scopus 로고    scopus 로고
    • Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletalmuscle
    • Maywood
    • Hernández-Ochoa EO, Robison P, Contreras M, Shen T, Zhao Z, Schneider MF: Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletalmuscle. Exp BiolMed (Maywood) 237: 1068- 1083, 2012.
    • (2012) Exp BiolMed , vol.237 , pp. 1068-1083
    • Hernández-Ochoa, E.O.1    Robison, P.2    Contreras, M.3    Shen, T.4    Zhao, Z.5    Schneider, M.F.6
  • 79
    • 84877769812 scopus 로고    scopus 로고
    • Vascular calcification in diabetes: Mechanisms and implications
    • Snell-Bergeon JK, Budoff MJ, Hokanson JE: Vascular calcification in diabetes: Mechanisms and implications. Curr Diab Rep 13: 391-402, 2013.
    • (2013) Curr Diab Rep , vol.13 , pp. 391-402
    • Snell-Bergeon, J.K.1    Budoff, M.J.2    Hokanson, J.E.3
  • 80
    • 78649983233 scopus 로고    scopus 로고
    • Role of NFAT5 in inflammatory disorders associated with osmotic stress
    • Neuhofer W: Role of NFAT5 in inflammatory disorders associated with osmotic stress. Curr Genomics 11: 584-590, 2010.
    • (2010) Curr Genomics , vol.11 , pp. 584-590
    • Neuhofer, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.