Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletal muscle

Experimental Biology and Medicine

Volumn 237, Issue 9, 2012, Pages 1068-1083

  Hernández Ochoa, Erick O ^a   Robison, Patrick ^a   Contreras, Minerva ^a   Shen, Tiansheng ^a   Zhao, Zhiyong ^a   Schneider, Martin F ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium; Hyperglycemia; Hypertonic stress; NFAT5; Skeletal muscle; Transverse tubular network

Indexed keywords

CALCINEURIN; GLUCOSE; MITOGEN ACTIVATED PROTEIN KINASE 14; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NUCLEAR FACTOR OF ACTIATED T CELL 5; UNCLASSIFIED DRUG; INDO 1; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; ELECTRIC FIELD; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FEMALE; GENETIC TRANSCRIPTION; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; MUSCLE HYPERTONIA; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; SKELETAL MUSCLE; TRANSVERSE TUBULAR SYSTEM; ANIMAL TISSUE; BLOOD ANALYSIS; CELL CULTURE; ENZYME ACTIVITY; FLEXOR MUSCLE; HYPEROSMOTIC STRESS; IMMUNOCYTOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; MALE; QUANTITATIVE ASSAY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CALCINEURIN; CALCIUM SIGNALING; DIABETES MELLITUS, TYPE 1; GLUCOSE; HYPERGLYCEMIA; MICE; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASE; TRANSCRIPTION FACTORS;

MURINAE; MUS;

EID: 84866456641     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2012.012052     Document Type: Article

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