The myokine irisin increases cortical bone mass

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 39, 2015, Pages 12157-12162

  Colaianni, Graziana ^a   Cuscito, Concetta ^a   Mongelli, Teresa ^a   Pignataro, Paolo ^a   Buccoliero, Cinzia ^a   Liu, Peng ^b   Lu, Ping ^b   Sartini, Loris ^c   Comite, Mariasevera D ^a   Mori, Giorgio ^d   Benedetto, Adriana D ^d   Brunetti, Giacomina ^a   Yuen, Tony ^b   Sun, Li ^b   Reseland, Janne E ^e   Colucci, Silvia ^a   New, Maria I ^b   Zaidi, Mone ^b   Cinti, Saverio ^c   Grano, Maria ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^d UNIVERSITY OF FOGGIA   (Italy)

^e UNIVERSITY OF OSLO   (Norway)

Author keywords

Mechanical loading; Osteoporosis; Sarcopenia

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BETA CATENIN; IRISIN; TRANSCRIPTION FACTOR RUNX2; FIBRONECTIN; FNDC5 PROTEIN, MOUSE; RECOMBINANT PROTEIN;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE DEVELOPMENT; BONE MASS; BONE STRENGTH; CONTROLLED STUDY; CORTICAL BONE; MALE; MOUSE; NONHUMAN; OSTEOCLAST; PERIOSTEUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRABECULAR BONE; WHITE ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METABOLISM; OSTEOBLAST; POLYMERASE CHAIN REACTION; SKELETAL MUSCLE;

ADIPOSE TISSUE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRONECTINS; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; OSTEOBLASTS; OSTEOGENESIS; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS;

EID: 84942917596     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1516622112     Document Type: Article

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