Signal transduction of mechanical stimuli is dependent on microfilament integrity: Identification of osteopontin as a mechanically induced gene in osteoblasts

Journal of Bone and Mineral Research

Volumn 12, Issue 10, 1997, Pages 1626-1636

  Toma, C D ^a,b,c   Ashkar, S ^b   Gray, M L ^d   Schaffer, J L ^b,c   Gerstenfeld, L C ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHALASIN D; FOCAL ADHESION KINASE; OSTEOPONTIN; PHORBOL 12 ACETATE 13 MYRISTATE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION REGULATION; MECHANICAL STIMULATION; MICROFILAMENT; MICROTUBULE ASSEMBLY; NONHUMAN; SECOND MESSENGER; SIGNAL TRANSDUCTION;

ANIMALS; CELL ADHESION; CELL ADHESION MOLECULES; CELLS, CULTURED; CHICK EMBRYO; COLCHICINE; CYCLOHEXIMIDE; CYTOCHALASIN D; ENZYME ACTIVATION; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICROFILAMENTS; NUCLEIC ACID SYNTHESIS INHIBITORS; OSTEOBLASTS; OSTEOPONTIN; PHOSPHOPROTEINS; PROTEIN KINASE C; PROTEIN SYNTHESIS INHIBITORS; PROTEIN-TYROSINE KINASES; RNA, MESSENGER; SIALOGLYCOPROTEINS; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TRANSCRIPTION FACTORS;

EID: 0030827291     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.10.1626     Document Type: Article

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