메뉴 건너뛰기




Volumn 10, Issue 1, 2010, Pages 56-63

Myostatin (GDF-8) as a key factor linking muscle mass and bone structure

Author keywords

ActRIIB; Bone density; GDF 8; Hypertrophy; Muscle bone interactions

Indexed keywords

MYOSTATIN;

EID: 77649198629     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (187)

References (54)
  • 1
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 1997;387:83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 2
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee SJ. Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol 2004;20:61-86.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 4
    • 0036200822 scopus 로고    scopus 로고
    • Suppression of body fat accumulation in myostatin-deficient mice
    • McPherron AC, Lee SJ. Suppression of body fat accumulation in myostatin-deficient mice. J Clin Invest 2002; 109:595-601.
    • (2002) J Clin Invest , vol.109 , pp. 595-601
    • McPherron, A.C.1    Lee, S.J.2
  • 5
    • 3142619579 scopus 로고    scopus 로고
    • Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders
    • Tsuchida K. Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders. Curr Drug Targets Immune Endocr Metabol Disord 2004;4:157-66.
    • (2004) Curr Drug Targets Immune Endocr Metabol Disord , vol.4 , pp. 157-166
    • Tsuchida, K.1
  • 6
    • 33646749327 scopus 로고    scopus 로고
    • Structure of the ternary signaling complex of a TGF-beta superfamily member
    • Allendorph GP, Vale WW, Choe S. Structure of the ternary signaling complex of a TGF-beta superfamily member. Proc Natl Acad Sci USA 2006;103:7643-8.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7643-7648
    • Allendorph, G.P.1    Vale, W.W.2    Choe, S.3
  • 7
    • 33645822277 scopus 로고    scopus 로고
    • Transcriptional profiling of myostatin-knockout mice implicates Wnt signaling in postnatal skeletal muscle growth and hypertrophy
    • Steelman CA, Recknor JC, Nettleton D, Reecy JM. Transcriptional profiling of myostatin-knockout mice implicates Wnt signaling in postnatal skeletal muscle growth and hypertrophy. Faseb J 2006;20:580-2.
    • (2006) Faseb J , vol.20 , pp. 580-582
    • Steelman, C.A.1    Recknor, J.C.2    Nettleton, D.3    Reecy, J.M.4
  • 8
    • 34248324912 scopus 로고    scopus 로고
    • The myostatin gene: Physiology and pharmacological relevance
    • Joulia-Ekaza D, Cabello G. The myostatin gene: physiology and pharmacological relevance. Curr Opin Pharmacol 2007;7:310-5.
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 310-315
    • Joulia-Ekaza, D.1    Cabello, G.2
  • 9
    • 0034864131 scopus 로고    scopus 로고
    • The developing bone: Slave or master of its cells and molecules?
    • Rauch F, Schoenau E. The developing bone: slave or master of its cells and molecules? Pediatr Res 2001;50:309-14.
    • (2001) Pediatr Res , vol.50 , pp. 309-314
    • Rauch, F.1    Schoenau, E.2
  • 10
    • 0034055123 scopus 로고    scopus 로고
    • Muscle, bone, and the Utah paradigm: A 1999 overview
    • Frost HM. Muscle, bone, and the Utah paradigm: a 1999 overview. Med Sci Sports Exerc 2000;32:911-7.
    • (2000) Med Sci Sports Exerc , vol.32 , pp. 911-917
    • Frost, H.M.1
  • 11
    • 0030816572 scopus 로고    scopus 로고
    • On our age-related bone loss: Insights from a new paradigm
    • Frost HM. On our age-related bone loss: insights from a new paradigm. J Bone Miner Res 1997;12:1539-46.
    • (1997) J Bone Miner Res , vol.12 , pp. 1539-1546
    • Frost, H.M.1
  • 12
    • 0023066530 scopus 로고
    • Effects of mechanical loads on surface morphology of the condylar cartilage of the mandible in rats
    • Bouvier M, Zimny ML. Effects of mechanical loads on surface morphology of the condylar cartilage of the mandible in rats. Acta Anat (Basel) 1987;129:293-300.
    • (1987) Acta Anat (Basel) , vol.129 , pp. 293-300
    • Bouvier, M.1    Zimny, M.L.2
  • 13
    • 0019152385 scopus 로고
    • Characteristics of growth-inducing exercise
    • Borer KT. Characteristics of growth-inducing exercise. Physiol Behav 1980;24:713-20.
    • (1980) Physiol Behav , vol.24 , pp. 713-720
    • Borer, K.T.1
  • 14
    • 0034007273 scopus 로고    scopus 로고
    • Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation
    • Montero A, Okada Y, Tomita M, Ito M, Tsurukami H, Nakamura T, et al. Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation. J Clin Invest 2000;105:1085-93.
    • (2000) J Clin Invest , vol.105 , pp. 1085-1093
    • Montero, A.1    Okada, Y.2    Tomita, M.3    Ito, M.4    Tsurukami, H.5    Nakamura, T.6
  • 16
    • 33646352965 scopus 로고    scopus 로고
    • Resistance to body fat gain in 'double-muscled' mice fed a high-fat diet
    • Hamrick MW, Pennington C, Webb CN, Isales CM. Resistance to body fat gain in 'double-muscled' mice fed a high-fat diet. Int J Obes (Lond) 2006;30:868-70.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 868-870
    • Hamrick, M.W.1    Pennington, C.2    Webb, C.N.3    Isales, C.M.4
  • 17
    • 0036654715 scopus 로고    scopus 로고
    • Bone mineral content and density in the humerus of adult myostatin-deficient mice
    • Hamrick MW, McPherron AC, Lovejoy CO. Bone mineral content and density in the humerus of adult myostatin-deficient mice. Calcif Tissue Int 2002;71:63-8.
    • (2002) Calcif Tissue Int , vol.71 , pp. 63-68
    • Hamrick, M.W.1    McPherron, A.C.2    Lovejoy, C.O.3
  • 18
    • 38349092250 scopus 로고    scopus 로고
    • Tendons of myostatin-deficient mice are small, brittle, and hypocellular
    • Mendias CL, Bakhurin KI, Faulkner JA. Tendons of myostatin-deficient mice are small, brittle, and hypocellular. Proc Natl Acad Sci USA 2008;105:388-93.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 388-393
    • Mendias, C.L.1    Bakhurin, K.I.2    Faulkner, J.A.3
  • 19
    • 0033842229 scopus 로고    scopus 로고
    • Femoral morphology and cross-sectional geometry of adult myostatin-deficient mice
    • Hamrick MW, McPherron AC, Lovejoy CO, Hudson J. Femoral morphology and cross-sectional geometry of adult myostatin-deficient mice. Bone 2000;27:343-9.
    • (2000) Bone , vol.27 , pp. 343-349
    • Hamrick, M.W.1    McPherron, A.C.2    Lovejoy, C.O.3    Hudson, J.4
  • 20
    • 0141891154 scopus 로고    scopus 로고
    • Increased bone mineral density in the femora of GDF8 knockout mice. Anat Rec A Discov Mol Cell
    • Hamrick MW. Increased bone mineral density in the femora of GDF8 knockout mice. Anat Rec A Discov Mol Cell Evol Biol 2003;272:388-91.
    • (2003) Evol Biol , vol.272 , pp. 388-391
    • Hamrick, M.W.1
  • 21
    • 33644530668 scopus 로고    scopus 로고
    • Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise
    • Hamrick MW, Samaddar T, Pennington C, McCormick J. Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise. J Bone Miner Res 2006;21:477-83.
    • (2006) J Bone Miner Res , vol.21 , pp. 477-483
    • Hamrick, M.W.1    Samaddar, T.2    Pennington, C.3    McCormick, J.4
  • 22
    • 34248584375 scopus 로고    scopus 로고
    • Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading
    • Hamrick MW, Shi X, Zhang W, Pennington C, Thakore H, Haque M, et al. Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading. Bone 2007;40:1544-53.
    • (2007) Bone , vol.40 , pp. 1544-1553
    • Hamrick, M.W.1    Shi, X.2    Zhang, W.3    Pennington, C.4    Thakore, H.5    Haque, M.6
  • 23
    • 57449118268 scopus 로고    scopus 로고
    • Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume
    • Kellum E, Starr H, Arounleut P, Immel D, Fulzele S, Wenger K, et al. Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume. Bone 2009;44:17-23.
    • (2009) Bone , vol.44 , pp. 17-23
    • Kellum, E.1    Starr, H.2    Arounleut, P.3    Immel, D.4    Fulzele, S.5    Wenger, K.6
  • 24
    • 0036181393 scopus 로고    scopus 로고
    • Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing
    • Cho TJ, Gerstenfeld LC, Einhorn TA. Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res 2002;17:513-20.
    • (2002) J Bone Miner Res , vol.17 , pp. 513-520
    • Cho, T.J.1    Gerstenfeld, L.C.2    Einhorn, T.A.3
  • 25
    • 0142241272 scopus 로고    scopus 로고
    • Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF-8 (myostatin)
    • Hamrick MW, Pennington C, Byron CD. Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF-8 (myostatin). J Orthop Res 2003;21:1025-32.
    • (2003) J Orthop Res , vol.21 , pp. 1025-1032
    • Hamrick, M.W.1    Pennington, C.2    Byron, C.D.3
  • 26
    • 64249143104 scopus 로고    scopus 로고
    • Redundancy of myostatin and growth/differentiation factor 11 function
    • McPherron AC, Huynh TV, Lee SJ. Redundancy of myostatin and growth/differentiation factor 11 function. BMC Dev Biol 2009;9:24.
    • (2009) BMC Dev Biol , vol.9 , pp. 24
    • McPherron, A.C.1    Huynh, T.V.2    Lee, S.J.3
  • 27
    • 0033052036 scopus 로고    scopus 로고
    • Regulation of anterior/ posterior patterning of the axial skeleton by growth/differentiation factor 11
    • McPherron AC, Lawler AM, Lee SJ. Regulation of anterior/ posterior patterning of the axial skeleton by growth/differentiation factor 11. Nat Genet 1999;22:260-4.
    • (1999) Nat Genet , vol.22 , pp. 260-264
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 28
    • 0030837018 scopus 로고    scopus 로고
    • The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse
    • Oh SP, Li E. The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. Genes Dev 1997;11:1812-26.
    • (1997) Genes Dev , vol.11 , pp. 1812-1826
    • Oh, S.P.1    Li, E.2
  • 29
    • 0033049661 scopus 로고    scopus 로고
    • Expression of growth/differentiation factor 11, a new member of the BMP/TGFbeta superfamily during mouse embryogenesis
    • Nakashima M, Toyono T, Akamine A, Joyner A. Expression of growth/differentiation factor 11, a new member of the BMP/TGFbeta superfamily during mouse embryogenesis. Mech Dev 1999;80:185-9.
    • (1999) Mech Dev , vol.80 , pp. 185-189
    • Nakashima, M.1    Toyono, T.2    Akamine, A.3    Joyner, A.4
  • 30
    • 0035862774 scopus 로고    scopus 로고
    • Gdf11 is a negative regulator of chondrogenesis and myogenesis in the developing chick limb
    • Gamer LW, Cox KA, Small C, Rosen V. Gdf11 is a negative regulator of chondrogenesis and myogenesis in the developing chick limb. Dev Biol 2001;229407-20.
    • (2001) Dev Biol , pp. 229407-229420
    • Gamer, L.W.1    Cox, K.A.2    Small, C.3    Rosen, V.4
  • 31
    • 0024075083 scopus 로고
    • Effects of age on the ability of the rat temporomandibular joint to respond to changing functional demands
    • Bouvier M. Effects of age on the ability of the rat temporomandibular joint to respond to changing functional demands. J Dent Res 1988;67:1206-12.
    • (1988) J Dent Res , vol.67 , pp. 1206-1212
    • Bouvier, M.1
  • 32
    • 33947395687 scopus 로고    scopus 로고
    • Pushing the limit: Masticatory stress and adaptive plasticity in mammalian craniomandibular joints
    • Ravosa MJ, Kunwar R, Stock SR, Stack MS. Pushing the limit: masticatory stress and adaptive plasticity in mammalian craniomandibular joints. J Exp Biol 2007; 210(Pt.4):628-41.
    • (2007) J Exp Biol , vol.210 , Issue.PART.4 , pp. 628-641
    • Ravosa, M.J.1    Kunwar, R.2    Stock, S.R.3    Stack, M.S.4
  • 33
    • 3042775279 scopus 로고    scopus 로고
    • Effects of increased muscle mass on mouse sagittal suture morphology and mechanics. Anat Rec A Discov Mol Cell
    • Byron CD, Borke J, Yu J, Pashley D, Wingard CJ, Hamrick M. Effects of increased muscle mass on mouse sagittal suture morphology and mechanics. Anat Rec A Discov Mol Cell Evol Biol 2004;279:676-84.
    • (2004) Evol Biol , vol.279 , pp. 676-684
    • Byron, C.D.1    Borke, J.2    Yu, J.3    Pashley, D.4    Wingard, C.J.5    Hamrick, M.6
  • 35
  • 36
    • 51849148703 scopus 로고    scopus 로고
    • Using "mighty mouse" to understand masticatory plasticity: Myostatin-deficient mice and musculoskeletal function
    • Ravosa MJ, Lopez EL, Menegaz RA, Stock SR, Stack MS, hamrick MW. Using "mighty mouse" to understand masticatory plasticity: myostatin-deficient mice and musculoskeletal function. Integr Comp Biol 2008;48:345-59.
    • (2008) Integr Comp Biol , vol.48 , pp. 345-359
    • Ravosa, M.J.1    Lopez, E.L.2    Menegaz, R.A.3    Stock, S.R.4    Stack, M.S.5    hamrick, M.W.6
  • 37
    • 51849150506 scopus 로고    scopus 로고
    • Enlargement of the temporalis muscle and alterations in the lateral cranial vault
    • Byron CD, Maness H, Yu JC, Hamrick MW. Enlargement of the temporalis muscle and alterations in the lateral cranial vault. Integr Comp Biol 2008;48:338-44.
    • (2008) Integr Comp Biol , vol.48 , pp. 338-344
    • Byron, C.D.1    Maness, H.2    Yu, J.C.3    Hamrick, M.W.4
  • 38
    • 28744452490 scopus 로고    scopus 로고
    • Biomineralization and adaptive plasticity of the temporomandibular joint in myostatin knockout mice
    • Nicholson EK, Stock SR, Hamrick MW, Ravosa MJ. Biomineralization and adaptive plasticity of the temporomandibular joint in myostatin knockout mice. Arch Oral Biol 2006;51:37-49.
    • (2006) Arch Oral Biol , vol.51 , pp. 37-49
    • Nicholson, E.K.1    Stock, S.R.2    Hamrick, M.W.3    Ravosa, M.J.4
  • 39
    • 36649003506 scopus 로고    scopus 로고
    • Association between myostatin gene polymorphisms and peak BMD variation in Chinese nuclear families
    • Zhang ZL, He JW, Qin YJ, Hu YQ, Li M, Zhang H, et al. Association between myostatin gene polymorphisms and peak BMD variation in Chinese nuclear families. Osteoporos Int 2008;19:39-47.
    • (2008) Osteoporos Int , vol.19 , pp. 39-47
    • Zhang, Z.L.1    He, J.W.2    Qin, Y.J.3    Hu, Y.Q.4    Li, M.5    Zhang, H.6
  • 40
    • 34548702201 scopus 로고    scopus 로고
    • In vivo evaluation of changes in body composition of transgenic mice expressing the myostatin pro domain using dual energy X-ray absorptiometry
    • Mitchell AD, Wall RJ. In vivo evaluation of changes in body composition of transgenic mice expressing the myostatin pro domain using dual energy X-ray absorptiometry. Growth Dev Aging 2007;70:25-37.
    • (2007) Growth Dev Aging , vol.70 , pp. 25-37
    • Mitchell, A.D.1    Wall, R.J.2
  • 41
    • 44049094434 scopus 로고    scopus 로고
    • The effects of myostatin on adipogenic differentiation of human bone marrow-derived mesenchymal stem cells are mediated through cross-communication between Smad3 and Wnt/beta-catenin signaling pathways
    • Guo W, Flanagan J, Jasuja R, Kirkland J, Jiang L, Bhasin S. The effects of myostatin on adipogenic differentiation of human bone marrow-derived mesenchymal stem cells are mediated through cross-communication between Smad3 and Wnt/beta-catenin signaling pathways. J Biol Chem 2008;283:9136-45.
    • (2008) J Biol Chem , vol.283 , pp. 9136-9145
    • Guo, W.1    Flanagan, J.2    Jasuja, R.3    Kirkland, J.4    Jiang, L.5    Bhasin, S.6
  • 42
    • 23044501742 scopus 로고    scopus 로고
    • Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells
    • Artaza JN, Bhasin S, Magee TR, Reisz-Porszasz S, Shen R, Groome NP, et al. Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells. Endocrinology 2005;146:3547-57.
    • (2005) Endocrinology , vol.146 , pp. 3547-3557
    • Artaza, J.N.1    Bhasin, S.2    Magee, T.R.3    Reisz-Porszasz, S.4    Shen, R.5    Groome, N.P.6
  • 43
    • 0141864365 scopus 로고    scopus 로고
    • Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis
    • Rebbapragada A, Benchabane H, Wrana JL, Celeste AJ, Attisano L. Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis. Mol Cell Biol 2003;23:7230-42.
    • (2003) Mol Cell Biol , vol.23 , pp. 7230-7242
    • Rebbapragada, A.1    Benchabane, H.2    Wrana, J.L.3    Celeste, A.J.4    Attisano, L.5
  • 44
    • 0032078468 scopus 로고    scopus 로고
    • Immunohistochemical detection of activin A, follistatin, and activin receptors during fracture healing in the rat
    • Nagamine T, Imamura T, Ishidou Y, Kato M, Murata F, ten Dijke P, et al. Immunohistochemical detection of activin A, follistatin, and activin receptors during fracture healing in the rat. J Orthop Res 1998;16:314-21.
    • (1998) J Orthop Res , vol.16 , pp. 314-321
    • Nagamine, T.1    Imamura, T.2    Ishidou, Y.3    Kato, M.4    Murata, F.5    ten Dijke, P.6
  • 46
    • 66049084853 scopus 로고    scopus 로고
    • Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets
    • Chelh I, Meunier B, Picard B, Reecy MJ, Chevalier C, Hocquette JF, et al. Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets. BMC Genomics 2009; 10:196.
    • (2009) BMC Genomics , vol.10 , pp. 196
    • Chelh, I.1    Meunier, B.2    Picard, B.3    Reecy, M.J.4    Chevalier, C.5    Hocquette, J.F.6
  • 47
    • 34548492947 scopus 로고    scopus 로고
    • Relationships between transforming growth factor-beta1, myostatin, and decorin: Implications for skeletal muscle fibrosis
    • Zhu J, Li Y, Shen W, Qiao C, Ambrosio F, Lavasani M, et al. Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis. J Biol Chem 2007;282:25852-63.
    • (2007) J Biol Chem , vol.282 , pp. 25852-25863
    • Zhu, J.1    Li, Y.2    Shen, W.3    Qiao, C.4    Ambrosio, F.5    Lavasani, M.6
  • 48
    • 50349094996 scopus 로고    scopus 로고
    • Myostatin directly regulates skeletal muscle fibrosis
    • Li ZB, Kollias HD, Wagner KR. Myostatin directly regulates skeletal muscle fibrosis. J Biol Chem 2008; 283:19371-8.
    • (2008) J Biol Chem , vol.283 , pp. 19371-19378
    • Li, Z.B.1    Kollias, H.D.2    Wagner, K.R.3
  • 49
    • 77649203944 scopus 로고    scopus 로고
    • Myostatin stimulates early tendon healing and responds to mechanical loading
    • Eliasson P, Andersson T, Aspenberg P. Myostatin stimulates early tendon healing and responds to mechanical loading. Trans Orthop Res Soc 234. 2009.
    • (2009) Trans Orthop Res Soc , vol.234
    • Eliasson, P.1    Andersson, T.2    Aspenberg, P.3
  • 50
    • 57449097320 scopus 로고    scopus 로고
    • Mice treated with myostatin/GDF-8 decoy receptor, ActRIIB-Fc, exhibit a tremendous increase in bone mass
    • Bialek P. Mice treated with myostatin/GDF-8 decoy receptor, ActRIIB-Fc, exhibit a tremendous increase in bone mass. Bone 2008;42/S1:S46.
    • (2008) Bone , vol.42 , Issue.S1
    • Bialek, P.1
  • 51
    • 85044010203 scopus 로고    scopus 로고
    • Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant musculoskeletal injury
    • in press
    • Hamrick MW, Arounleut P, Kellum E, Cain M, Immel D, Liang L. Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant musculoskeletal injury. J Trauma; in press.
    • J Trauma
    • Hamrick, M.W.1    Arounleut, P.2    Kellum, E.3    Cain, M.4    Immel, D.5    Liang, L.6
  • 52
    • 77649198942 scopus 로고    scopus 로고
    • Hamrick M, Arounleut P, Kellum E, Cain M, Elkasrawy M, F S, et al. Effects of recombinant myostatin propeptide on fracture repair in a fibula osteotomy model. Trans Orthop Res Soc 0936. 2009.
    • Hamrick M, Arounleut P, Kellum E, Cain M, Elkasrawy M, F S, et al. Effects of recombinant myostatin propeptide on fracture repair in a fibula osteotomy model. Trans Orthop Res Soc 0936. 2009.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.