The perioperative immune response

Current Opinion in Critical Care

Volumn 21, Issue 4, 2015, Pages 336-342

  Oâ Dwyer, Michael J ^a,b   Owen, Helen C ^a   Torrance, Hew D T ^a,b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

Anaesthesia; Epigenetics; Immunomodulation; Inflammation; Tissue damage; Transfusion

Indexed keywords

DEXAMETHASONE; ANALGESIC AGENT; ANESTHETIC AGENT; CYTOKINE;

ADAPTIVE IMMUNITY; BLOOD TRANSFUSION; CANCER RECURRENCE; CLINICAL PRACTICE; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; GENE EXPRESSION ASSAY; HUMAN; IMMUNE EVASION; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; INNATE IMMUNITY; PERIOPERATIVE PERIOD; REVIEW; TISSUE INJURY; BLOOD AUTOTRANSFUSION; CHEMICALLY INDUCED; GENETICS; IMMUNITY; IMMUNOLOGY; INTENSIVE CARE; PHYSIOLOGY;

ANALGESICS; ANESTHETICS; BLOOD TRANSFUSION, AUTOLOGOUS; CRITICAL CARE; CYTOKINES; HUMANS; IMMUNE SYSTEM PROCESSES; INFLAMMATION; PERIOPERATIVE PERIOD;

EID: 84942916818     PISSN: 10705295     EISSN: 15317072     Source Type: Journal    
DOI: 10.1097/MCC.0000000000000213     Document Type: Review

References (56)

1. Lord JM, Midwinter MJ, Chen YF, et al. The systemic immune response to trauma: an overview of pathophysiology and treatment. Lancet 2014; 384:1455-1465.
2. Oppenheim JJ, Yang D. Alarmins: chemotactic activators of immune responses. Curr Opin Immunol 2005; 17:359-365.
3. Chan JK, Roth J, Oppenheim JJ, et al. Alarmins: awaiting a clinical response. J Clin Invest 2012; 122:2711-2719.
4. Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4:499-511.
5. Manson J, Thiemermann C, Brohi K. Trauma alarmins as activators of damageinduced inflammation. Br J Surg 2012; 99 (Suppl 1):12-20.
6. Bianchi ME, Manfredi AA. High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol Rev 2007; 220:35-46.
7. Mokart D, Leone M, Sannini A, et al. Predictive perioperative factors for developing severe sepsis after major surgery. Br J Anaesth 2005; 95:776-781.
8. Giannoudis PV, Smith RM, Perry SL, et al. Immediate IL-10 expression following major orthopaedic trauma: relationship to anti-inflammatory response and subsequent development of sepsis. Intensive Care Med 2000; 26:1076-1081.
9. Baigrie RJ, Lamont PM, Kwiatkowski D, et al. Systemic cytokine response after major surgery. Br J Surg 1992; 79:757-760.
10. Fragkou P, Torrance HD, Ackland G, et al. Major gastrointestinal surgery is associated with a specific gene expression profile that is quantitatively associated with infectious complications. Eur J Anaesthesiol 2014; 31 (Suppl 52): 14.
11. Diehl S, Rincon M. The two faces of IL-6 on Th1/Th2 differentiation. Mol Immunol 2002; 39:531-536.
12. Wakefield CH, Carey PD, Foulds S, et al. Changes in major histocompatibility complex class II expression in monocytes and T cells of patients developing infection after surgery. Br J Surg 1993; 80:205-209.
13. Cheron A, Floccard B, Allaouchiche B, et al. Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma. Crit Care 2010; 14:R208.
14. White M, Martin-Loeches I, Lawless MW, et al. Hospital-Acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression. Chest 2011; 139:626-632.
15. Xiao W, Mindrinos MN, Seok J, et al. A genomic storm in critically injured humans. J Exp Med 2011; 208:2581-2590.
16. Gaudilliere B, Fragiadakis GK, Bruggner RV, et al. Clinical recovery from surgery correlates with single-cell immune signatures. Sci Transl Med 2014; 6:255ra131.
17. Gabrilovich DI, Bronte V, Chen SH, et al. The terminology issue for myeloidderived suppressor cells. Cancer Res 2007; 67:425; author reply 426.
18. Schmielau J, Finn OJ. Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients. Cancer Res 2001; 61:4756-4760.
19. Highfill SL, Rodriguez PC, Zhou Q, et al. Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13. Blood 2010; 116:5738-5747.
20. Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 2009; 182:4499-4506.
21. Pillay J, Kamp VM, van Hoffen E, et al. A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J Clin Invest 2012; 122:327-336.
22. Pillay J, Tak T, Kamp VM, et al. Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences. Cell Mol Life Sci 2013; 70:3813-3827.
23. Lahiri R, Derwa Y, Bashir Z, et al. Systemic inflammatory response syndrome (SIRS) after major abdominal surgery is predicted by early upregulation of TLR4 and TLR5. Ann Surg (in press).
24. Matsuoka H, Kurosawa S, Horinouchi T, et al. Inhalation anesthetics induce apoptosis in normal peripheral lymphocytes in vitro. Anesthesiology 2001; 95:1467-1472.
25. Picq CA, Clarencon D, Sinniger VE, et al. Impact of anesthetics on immune functions in a rat model of vagus nerve stimulation. PLoS One 2013; 8:e67086.
26. Vallejo R, de Leon-Casasola O, Benyamin R. Opioid therapy and immunosuppression: a review. Am J Ther 2004; 11:354-365.
27. Markovic SN, Knight PR, Murasko DM. Inhibition of interferon stimulation of natural killer cell activity in mice anesthetized with halothane or isoflurane. Anesthesiology 1993; 78:700-706.
28. Hotchkiss RS, Moldawer LL. Parallels between cancer and infectious disease. N Engl J Med 2014; 371:380-383.
29. Milosavljevic SB, Pavlovic AP, Trpkovic SV, et al. Influence of spinal and general anesthesia on the metabolic, hormonal, and hemodynamic response in elective surgical patients. Med Sci Monit 2014; 20:1833-1840.
30. Liu J, Ma C, Elkassabany N, et al. Neuraxial anesthesia decreases postoperative systemic infection risk compared with general anesthesia in knee arthroplasty. Anesth Analg 2013; 117:1010-1016.
31. Chen WK, Ren L, Wei Y, et al. General anesthesia combined with epidural anesthesia ameliorates the effect of fast-track surgery by mitigating immunosuppression and facilitating intestinal functional recovery in colon cancer patients. Int J Colorectal Dis 2015; 30:475-481.
32. Cheng YC, Cheng XB, Li XJ, et al. Combined general and regional anesthesia and effects on immune function in patients with benign ovarian tumors treated by laparoscopic therapy. Int J Clin Exp Med 2013; 6:716-719.
33. Pei L, Tan G, Wang L, et al. Comparison of combined general-epidural anesthesia with general anesthesia effects on survival and cancer recurrence: a meta-Analysis of retrospective and prospective studies. PLoS One 2014; 9:e114667.
34. Memtsoudis SG, Sun X, Chiu YL, et al. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anesthesiology 2013; 118:1046-1058.
35. Buggy DJ, Borgeat A, Cata J, et al. Consensus statement from the BJA workshop on cancer and anaesthesia. Br J Anaesth 2015; 114:2-3.
36. Elston MS, Conaglen HM, Hughes C, et al. Duration of cortisol suppression following a single dose of dexamethasone in healthy volunteers: a randomised double-blind placebo-controlled trial. Anaesth Intensive Care 2013; 41:596-601.
37. Bolac CS, Wallace AH, Broadwater G, et al. The impact of postoperative nausea and vomiting prophylaxis with dexamethasone on postoperative wound complications in patients undergoing laparotomy for endometrial cancer. Anesth Analg 2013; 116:1041-1047.
38. Percival VG, Riddell J, Corcoran TB. Single dose dexamethasone for postoperative nausea and vomiting: a matched case-control study of postoperative infection risk. Anaesth Intensive Care 2010; 38:661-666.
39. Corcoran TB, Truyens EB, Ng A, et al. Antiemetic dexamethasone and postoperative infection risk: a retrospective cohort study. Anaesth Intensive Care 2010; 38:654-660.
40. Waldron NH, Jones CA, Gan TJ, et al. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and metaanalysis. Br J Anaesth 2013; 110:191-200.
41. Mathiesen O, Wetterslev J, Kontinen VK, et al. Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review. Acta Anaesthesiol Scand 2014; 58:1182-1198.
42. Opelz G, Terasaki PI. Improvement of kidney-graft survival with increased numbers of blood transfusions. N Engl J Med 1978; 299:799-803.
43. Amato A, Pescatori M. Perioperative blood transfusions for the recurrence of colorectal cancer. Cochrane Database Syst Rev 2006:CD005033.
44. Cata JP, Wang H, Gottumukkala V, et al. Inflammatory response, immunosuppression, and cancer recurrence after perioperative blood transfusions. Br J Anaesth 2013; 110:690-701.
45. Jensen LS, Andersen AJ, Christiansen PM, et al. Postoperative infection and natural killer cell function following blood transfusion in patients undergoing elective colorectal surgery. Br J Surg 1992; 79:513-516.
46. Soubra A, Zabell JR, Adejoro O, et al. Effect of perioperative blood transfusion on mortality for major urologic malignancies. Clin Genitourin Cancer 2014. [Epub ahead of print]
47. Schiergens TS, Rentsch M, Kasparek MS, et al. Impact of perioperative allogeneic red blood cell transfusion on recurrence and overall survival after resection of colorectal liver metastases. Dis Colon Rectum 2015; 58:74-82.
48. Danan D, Smolkin ME, Varhegyi NE, et al. Impact of blood transfusions on patients with head and neck cancer undergoing free tissue transfer. Laryngoscope 2015; 125:86-91.
49. Fragkou PC, Torrance HD, PearseRM, et al. Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study. Crit Care 2014; 18:541.
50. Torrance HD, Brohi K, Pearse RM, et al. Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Ann Surg 2014; 261:751-759.
51. Atzil S, Arad M, Glasner A, et al. Blood transfusion promotes cancer progression: a critical role for aged erythrocytes. Anesthesiology 2008; 109:989-997.
52. Torrance HD, Vivian ME, Brohi K, et al. Changes in gene expression following trauma are related to the age of transfused packed red blood cells. J Trauma Acute Care Surg 2015; 78:535-542.
53. Héninger E, Krueger TEG, Lang JM. Augmenting antitumor immune responses with epigenetic modifying agents. Front Immunol 2015; 6:1-14.
54. Lirk P, Fiegl H, Weber NC, et al. Epigenetics in the perioperative period. Br J Pharmacol 2014. [Epub ahead of print]
55. Doehring A, Oertel BG, Sittl R, et al. Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain. Pain 2013; 154:15-23.
56. Owen HC, Torrance HD, Brohi K, et al. MicroRNA-regulated immunosuppression in severely injured polytrauma patients. Intensive Care Med Exp 2014; 2 (Suppl 1):84.