Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: A prospective cohort study

Critical Care

Volumn 18, Issue 5, 2014, Pages

  Fragkou, Paraskevi C ^a,b   Torrance, Hew D ^a,b   Pearse, Rupert M ^a,b   Ackland, Gareth L ^c   Prowle, John R ^a   Owen, Helen C ^b   Hinds, Charles J ^a,b   O'Dwyer, Michael J ^a,b  

^a ROYAL LONDON HOSPITAL   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 23; MESSENGER RNA; RAR RELATED ORPHAN RECEPTOR GAMMA T; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE;

ABDOMINAL INFECTION; ADULT; AGED; ARTICLE; BLOOD TRANSFUSION; BLOODSTREAM INFECTION; CATHETER INFECTION; COHORT ANALYSIS; DISEASE PREDISPOSITION; DISEASE SEVERITY; DOWN REGULATION; FEMALE; GASTROINTESTINAL SURGERY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HOSPITAL MORTALITY; HOSPITAL PATIENT; HUMAN; IMMUNE DEFICIENCY; IMMUNOMODULATION; INFECTION RISK; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MAJOR SURGERY; MALE; PERIOPERATIVE PERIOD; PHENOTYPE; PNEUMONIA; POSTOPERATIVE INFECTION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SKIN INFECTION; SURGICAL INFECTION; TH1 CELL; TH17 CELL; URINARY TRACT INFECTION; ABDOMINAL SURGERY; ADVERSE EFFECTS; CROSS INFECTION; ELECTIVE SURGERY; GENE EXPRESSION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LEUKOCYTE COUNT; METABOLISM; MIDDLE AGED; MORTALITY;

AGED; BLOOD TRANSFUSION; CROSS INFECTION; CYTOKINES; DIGESTIVE SYSTEM SURGICAL PROCEDURES; DISEASE SUSCEPTIBILITY; ELECTIVE SURGICAL PROCEDURES; FEMALE; GENE EXPRESSION; HOSPITAL MORTALITY; HUMANS; IMMUNE TOLERANCE; LEUKOCYTE COUNT; MALE; MIDDLE AGED; PERIOPERATIVE PERIOD; PROSPECTIVE STUDIES; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 84929940231     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-014-0541-x     Document Type: Article

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