Label-free quantitative proteomics of mouse cerebrospinal fluid detects β-site APP cleaving enzyme (BACE1) protease substrates in vivo

Molecular and Cellular Proteomics

Volumn 14, Issue 10, 2015, Pages 2550-2563

  Dislich, Bastian ^a,b   Wohlrab, Felix ^a,b   Bachhuber, Teresa ^c   Müller, Stephan A ^a,b   Kuhn, Peer Hendrik ^b,e   Hogl, Sebastian ^a,b   Meyer Luehmann, Melanie ^d   Lichtenthaler, Stefan F ^a,b,e,f  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f Germany 3 Munich Cluster for Systems Neurology   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APLP1 PROTEIN; APLP2 PROTEIN; ATP6AP1 PROTEIN; AXONIN 1; BETA SECRETASE 1; CDH13 PROTEIN; CDH2 PROTEIN; CHL1 PROTEIN; CNTN2 PROTEIN; DAG1 PROTEIN; EFNB3 PROTEIN; ENPP5 PROTEIN; MEMBRANE PROTEIN; NUCLEOTIDE PYROPHOSPHATASE; PLEXIN; PLEXIN DOMAIN CONTAINING 2; PLXDC2 PROTEIN; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE N2; PTPRN2 PROTEIN; QSOX1 PROTEIN; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; BACE1 PROTEIN, MOUSE; BIOLOGICAL MARKER; CELL SURFACE RECEPTOR; PHOSPHODIESTERASE; PLXDC2 PROTEIN, HUMAN; PTPRN2 PROTEIN, HUMAN; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE; SECRETASE;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN CELL; CELL COMMUNICATION; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; EMBRYO; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF QUANTITATION; LIPID METABOLISM; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CEREBROSPINAL FLUID; FEMALE; GENETICS; HEK293 CELL LINE; KNOCKOUT MOUSE; MALE; METABOLISM; PROCEDURES;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BIOMARKERS; FEMALE; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORIC DIESTER HYDROLASES; PROTEOMICS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 8; RECEPTORS, CELL SURFACE;

EID: 84942908544     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M114.041533     Document Type: Article

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