Secalonic Acid-D represses HIF1α/VEGF-mediated angiogenesis by regulating the Akt/mTOR/p70S6K signaling cascade

Cancer Research

Volumn 75, Issue 14, 2015, Pages 2886-2896

  Guru, Santosh Kumar ^a   Pathania, Anup Singh ^a,b   Kumar, Suresh ^a,b   Ramesh, Deshidi ^a,b   Kumar, Manjeet ^a   Rana, Satiander ^a   Kumar, Ajay ^a   Malik, Fayaz ^a,b,c   Sharma, P R ^a   Chandan, B K ^a   Jaglan, Sundeep ^a   Sharma, J P ^a   Shah, Bhahwal Ali ^a   Tasduq, Sheikh Abdullah ^a   Lattoo, Surrinder K ^a   Faruk, Abdul ^d   Saxena, A K ^a,b   Vishwakarma, R A ^a,b   Bhushan, Shashi ^a,b  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

^c UNIVERSITY OF MICHIGAN   (United States)

^d GURU NANAK DEV UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; GELATINASE A; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; S6 KINASE; SECALONIC ACID D; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; SECALONIC ACID; TARGET OF RAPAMYCIN KINASE; VASCULOTROPIN A; XANTHONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR RING; ANIMAL; C57BL MOUSE; CELL CULTURE; DOWN REGULATION; DRUG EFFECTS; GENETICS; MCF 7 CELL LINE; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; PHYSIOLOGY;

ANIMALS; CELLS, CULTURED; DOWN-REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MCF-7 CELLS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XANTHONES;

EID: 84942898489     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-2312     Document Type: Article

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