Antiproliferative and antiproteolytic activity of pentoxifylline in cultures of B16F10 melanoma cells

Cancer Chemotherapy and Pharmacology

Volumn 58, Issue 2, 2006, Pages 195-202

  Dua, Pooja ^a   Gude, Rajiv P ^a  

^a CANCER RESEARCH INSTITUTE   (India)

Author keywords

Adhesion; B16f10 melanoma; Matrix metalloproteinases; Pentoxifylline; Proliferation

Indexed keywords

GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; PENTOXIFYLLINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ADHESION; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRUCTURE; COLONY FORMATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME RELEASE; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; IC 50; IN VITRO STUDY; MELANOMA CELL; MOUSE; NONHUMAN; PERIPHERAL VASCULAR DISEASE; PRIORITY JOURNAL; WESTERN BLOTTING; ZYMOGRAPHY;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; HYDROLYSIS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MELANOMA, EXPERIMENTAL; MICE; NEOPLASM PROTEINS; PENTOXIFYLLINE;

EID: 33646477131     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-005-0155-8     Document Type: Article

References (33)

1. Amirkhosravi A, Warnes G, Biggerstaff J, Malik Z, May K, Francis JL (1997) The effect of pentoxifylline on spontaneous and experimental metastasis of the mouse Neuro2a neuroblastoma. Clin Exp Metastasis 4:453-461
2. Bennewith KL, Durand RE (2001) Drug-induced alterations in tumor perfusion yield increases in tumor cell radiosensitivity. Br J Cancer 85:1577-1584
3. Brinckerhoff CE, Matrician LM (2002) Matrix metalloproteases a tail of frog that became a Prince. Nat Rev Mol Cell Biol 3:204-221
4. Chun-Lin Ye, Jian-Wen Liu, Dong-Zhi Wei, Yan-Hua Lu, Feng Qian (2004). In vitro anti-tumor activity of 2′, 4′-dihydroxy-6′-methoxy- 3′,5′-dimethylchalcone against six established human cancer cell lines. Pharmacol Res 50(5):505-510
5. Demierre MF, Nathanson L (2003) Chemoprevention of melanoma: an unexplored strategy. J Clin Oncol 21:158-165
6. Ducloux D, Bresson Vautrin C, Chalopin J (2001) Use of pentoxifylline in membranous nephropathy. Lancet 357:1672-1673
7. Edward M, Gold JA, Mackie RM (1988) Different susceptibilities of melanoma cell to retinoic acid-induced changes in melanotic expression. Biochem Biophys Res Commun 155:773-778
8. Felding HB (2003) Integrin adhesion receptors in tumor metastasis. Clin Exp Metastasis 20:203-213
9. Fidler IJ (1973) Selection of successive tumor lines for metastasis. Nat (New Biol) 242:148-149
10. Gallagher HC, Bacon CL, Odumeru OA, Gallagher KF, Fitzpatrick T, Regan CM (2004) Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression. Neurotoxicol Teratol 26:73-81
11. Gude RP, Binda MM, Boquete AL, Bonfil RD (2001). Inhibition of endothelial cell proliferation and tumor induced angiogenesis by pentoxifylline. J Cancer Res Clin Oncol 127:625-630
12. Gude RP, Binda MM, Prasas HL, Andres JP, Klein-Santo R, Bonfil D (1996) Studies on mechanisms responsible for inhibition of experimental metastasis of B16F10 murine melanoma by pentoxifyllline. J Biomed Sci 6:133-141
13. Gude RP, Ingle AD, Rao SGA (1996) Inhibition on lung homing of B16F10 by Pentoxifylline, microfilament depolymerising agent. Cancer Lett 106:171-176
14. Kleiner DE, Stetler Stevenson WG (1999) Matrix metalloproteinase and metastasis. Cancer Chemother Pharmacol 43(Suppl):542
15. Lazarczyk M, Grzela T, Niderla J, Lazarczyk MA, Milewski L, Dziunycz P, Skopinski P, Golab J (2004) Differential influence of Pentoxifylline on murine colon adenocarcinoma and melanoma derived metastatic tumor development in lungs. Oncol Rep 11:1121-1125
16. Liotta LA, Rao CN, Wewer UM (1986) Biochemical interactions of tumor cells with the basement membrane. Annu Rev Biochem 55:1037-1057
17. LiYe-Xiong S Lin -Quan, Weber-Johnson K (1999). Potentiation of cytotoxicity and radiosensitization of E-2-deoxy-2′-(flouromethylene) cytidine by pentoxifylline in vitro. Int J Cancer 80:155-160
18. Marnett LJ (1992) Aspirin and role of prostaglandins in colon cancer. Cancer Res 52:5575-5589
19. Mazzieri R, Masiero L, Zanetta L, Monea S, Onisto M, Garbisa S, Mignatti P (1997) Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants. Embo J 16:2319-2332
20. Nicholson C D, Challiss RAJ, Shahid M (1991) Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. Trends Pharmacol Sci 12:19-27
21. Novick WJ, Sullivan G (1990) New Pharmacological Studies with pentoxifylline In: Schimid GM (eds) Biorhology. Schonbein Perogamon Press, USA, 27:449-454
22. Okada Y, Tsuchiya H, Shimizu H, Tomita K, Nakanishi I, Sato H, Seiki M, Yamashita K, Hayakawa T (1990). Induction and stimulation of 92-kDa gelatinase type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor alpha. Biochem Biophys Res Commun 171:610
23. Pavey S, Gabrielli B (2002) Alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiation. Cancer Res 62:875-80
24. Peracchia F, Tamburro A, Prontera C, Mariani B, Rotilio D (1997) cAMP involvement in the expression of MMP-2 and MT-MMP1 metalloproteinases in human endothelial cells. Arterioscler Thromb Vasc Biol 17:3185-3190
25. Philip S, Bulbule A, Kundu GC (2001) Activation of promatrix metalloproteinase-2 through nuclear factor-κB mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells. J Biol Chem 276:44926-44935
26. Ries C, Kolb H, Petrides PE (1994) Regulation of 92-kD gelatinase release in HL-60 leukemia cells: Tumor Necrosis Factor-α as an autocrine stimulus for basal and phorbol ester induced secretion. Blood 183:3638-3646
27. Salo T, Liotta LA, Tryggvason K(1983) Purification and characterization of a murine basement membrane collagen-degrading enzyme secreted by metastatic tumor cells. J Biol Chem 258:3058-3063
28. Tatematsu H; Kilkuskie RE; Corrigan AJ; Bodner AJ; Lee K H (1991). Anti-AIDS agents, 3. Inhibitory effects of colchicine derivatives on HIV replication in H9 lymphocyte cells. J Nat Prod 54(2):632-637
29. Teicher BA, Herman TS, Tanaka J, Dezube B, Pardee A, Frei E 3rd (1991). Fluosol-DA/carbogen with lonidamine or pentoxifylline as modulators of alkylating agents in the FSaIIC fibrosarcoma. Cancer Chemother Pharmacol 28(1):45-50
30. Teicher BA, Holden SA, Herman TS, Epelbaum R, Pardee AB, Dezube B (1991). Efficacy of pentoxifylline as a modulator of alkylating agent activity in vitro and in vivo. Anticancer Res 11(4):1555-1560
31. Toth M, Chvyrkova I, Bernardo M, Barrantes SH, Fridman R (2003) Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes. Biochem Biophys Res Commun 108:386-395
32. Tryggvason K, Hoyhtya M, Salo T (1987) Proteolytic degradation of extracellular matrix in tumor invasion. Biochem Biophys Acta 907:191-217
33. Vihinen P and Kahari VM (2002) Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets. Int J Cancer 99:157-166