Anticancer activity, toxicity and pharmacokinetic profile of an indanone derivative

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 5, 2012, Pages 988-995

  Chanda, Debabrata ^a   Bhushan, Shashi ^b   Guru, Santosh K ^b   Shanker, Karuna ^a   Wani, Z A ^b   Rah, B A ^b   Luqman, Suaib ^a   Mondhe, Dilip M ^b   Pal, Anirban ^a   Negi, Arvind S ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Acute oral toxicity; Gallic acid; In vivo anticancer activity; Indanone; Pharmacokinetics; Tubulin polymerisation inhibition

Indexed keywords

3 (3',4',5' TRIMETHOXYPHENYL) 4,5,6 TRIMETHOXY 1 INDANONE; FLUOROURACIL; GALLIC ACID; HYPOXIA INDUCIBLE FACTOR 1; INDANONE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASCITES TUMOR; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG TOLERABILITY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CARCINOMA, EHRLICH TUMOR; CELL CYCLE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FEMALE; HUMANS; INDANS; LEUKOCYTES; MALE; MICE; NF-KAPPA B; RABBITS; TUBULIN MODULATORS;

EID: 84868701468     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.08.013     Document Type: Article

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