메뉴 건너뛰기




Volumn 75, Issue 11, 2015, Pages 2254-2263

Hepcidin regulation in prostate and its disruption in prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; AXIN; AZACITIDINE; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 4; FERROPORTIN; GLYCOGEN SYNTHASE KINASE 3BETA; HEPCIDIN; INTERLEUKIN 6; LYMPHOID ENHANCER FACTOR 1; OSTEOGENIC PROTEIN 1; PROSTATE SPECIFIC ANTIGEN; SCLEROSTIN; SCLEROSTIN DOMAIN CONTAINING 1 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; IRON; PROTEIN; SOSTDC1 PROTEIN, HUMAN;

EID: 84942888188     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-2465     Document Type: Article
Times cited : (137)

References (44)
  • 1
    • 84861355868 scopus 로고    scopus 로고
    • Hepcidin and iron homeostasis
    • Ganz T, Nemeth E. Hepcidin and iron homeostasis. Biochim Biophys Acta 2012;1823:1434-43.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 1434-1443
    • Ganz, T.1    Nemeth, E.2
  • 2
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004;306:2090-3.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6
  • 3
    • 70349325941 scopus 로고    scopus 로고
    • Iron sequestration and anemia of inflammation
    • Ganz T, Nemeth E. Iron sequestration and anemia of inflammation. Semin Hematol 2009;46:387-93.
    • (2009) Semin Hematol , vol.46 , pp. 387-393
    • Ganz, T.1    Nemeth, E.2
  • 5
    • 84862792124 scopus 로고    scopus 로고
    • Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation
    • Sun CC, Vaja V, Babitt JL, Lin HY. Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation. Am J Hematol 2012;87:392-400.
    • (2012) Am J Hematol , vol.87 , pp. 392-400
    • Sun, C.C.1    Vaja, V.2    Babitt, J.L.3    Lin, H.Y.4
  • 8
    • 84855197344 scopus 로고    scopus 로고
    • Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection
    • Schwarz P, Kubler JA, Strnad P, Muller K, Barth TF, Gerloff A, et al. Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection. Gut 2012;61:193-201.
    • (2012) Gut , vol.61 , pp. 193-201
    • Schwarz, P.1    Kubler, J.A.2    Strnad, P.3    Muller, K.4    Barth, T.F.5    Gerloff, A.6
  • 10
    • 84890555121 scopus 로고    scopus 로고
    • Prostate cancer progression after androgen deprivation therapy: Mechanisms of castrate resistance and novel therapeutic approaches
    • Karantanos T, Corn PG, Thompson TC. Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches. Oncogene 2013;32:5501-11.
    • (2013) Oncogene , vol.32 , pp. 5501-5511
    • Karantanos, T.1    Corn, P.G.2    Thompson, T.C.3
  • 11
    • 73849106797 scopus 로고    scopus 로고
    • E-cadherin-mediated survival of androgen- receptor-expressing secretory prostate epithelial cells derived from a stratified in vitro differentiation model
    • Lamb LE, Knudsen BS, Miranti CK. E-cadherin-mediated survival of androgen- receptor-expressing secretory prostate epithelial cells derived from a stratified in vitro differentiation model. J Cell Sci 2010;123:266-76.
    • (2010) J Cell Sci , vol.123 , pp. 266-276
    • Lamb, L.E.1    Knudsen, B.S.2    Miranti, C.K.3
  • 14
    • 79959875910 scopus 로고    scopus 로고
    • DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer
    • Kobayashi Y, Absher DM, Gulzar ZG, Young SR, McKenney JK, Peehl DM, et al. DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer. Genome Res 2011;21:1017-27.
    • (2011) Genome Res , vol.21 , pp. 1017-1027
    • Kobayashi, Y.1    Absher, D.M.2    Gulzar, Z.G.3    Young, S.R.4    McKenney, J.K.5    Peehl, D.M.6
  • 15
    • 84868312894 scopus 로고    scopus 로고
    • Identification of new differentially methylated genes that have potential functional consequences in prostate cancer
    • Kim JW, Kim ST, Turner AR, Young T, Smith S, Liu W, et al. Identification of new differentially methylated genes that have potential functional consequences in prostate cancer. PLoS ONE 2012;7:e48455.
    • (2012) PLoS ONE , vol.7 , pp. e48455
    • Kim, J.W.1    Kim, S.T.2    Turner, A.R.3    Young, T.4    Smith, S.5    Liu, W.6
  • 16
    • 78649475003 scopus 로고    scopus 로고
    • Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
    • Du P, Zhang X, Huang CC, Jafari N, Kibbe WA, Hou L, et al. Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinformatics 2010;11:587.
    • (2010) BMC Bioinformatics , vol.11 , pp. 587
    • Du, P.1    Zhang, X.2    Huang, C.C.3    Jafari, N.4    Kibbe, W.A.5    Hou, L.6
  • 17
    • 33646370235 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
    • Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 2006;38:531-9.
    • (2006) Nat Genet , vol.38 , pp. 531-539
    • Babitt, J.L.1    Huang, F.W.2    Wrighting, D.M.3    Xia, Y.4    Sidis, Y.5    Samad, T.A.6
  • 20
    • 84864017887 scopus 로고    scopus 로고
    • Interleukin-6: A multifunctional targetable cytokine in human prostate cancer
    • Culig Z, Puhr M. Interleukin-6: a multifunctional targetable cytokine in human prostate cancer. Mol Cell Endocrinol 2012;360:52-8.
    • (2012) Mol Cell Endocrinol , vol.360 , pp. 52-58
    • Culig, Z.1    Puhr, M.2
  • 21
    • 77952548279 scopus 로고    scopus 로고
    • Extracellular BMP-antagonist regulation in development and disease: Tied up in knots
    • Walsh DW, Godson C, Brazil DP, Martin F. Extracellular BMP-antagonist regulation in development and disease: tied up in knots. Trends Cell Biol 2010;20:244-56.
    • (2010) Trends Cell Biol , vol.20 , pp. 244-256
    • Walsh, D.W.1    Godson, C.2    Brazil, D.P.3    Martin, F.4
  • 25
    • 84881231573 scopus 로고    scopus 로고
    • SOSTDC1 down-regulation of expression involves CpG methylation and is a potential prognostic marker in gastric cancer
    • Gopal G, Raja UM, Shirley S, Rajalekshmi KR, Rajkumar T. SOSTDC1 down-regulation of expression involves CpG methylation and is a potential prognostic marker in gastric cancer. Cancer Genet 2013;206:174-82.
    • (2013) Cancer Genet , vol.206 , pp. 174-182
    • Gopal, G.1    Raja, U.M.2    Shirley, S.3    Rajalekshmi, K.R.4    Rajkumar, T.5
  • 27
    • 21244480924 scopus 로고    scopus 로고
    • Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
    • Li X, Zhang Y, Kang H, Liu W, Liu P, Zhang J, et al. Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem 2005;280: 19883-7.
    • (2005) J Biol Chem , vol.280 , pp. 19883-19887
    • Li, X.1    Zhang, Y.2    Kang, H.3    Liu, W.4    Liu, P.5    Zhang, J.6
  • 28
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell 2012; 149:1192-205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 29
    • 58249122326 scopus 로고    scopus 로고
    • Small moleculemediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
    • Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, et al. Small moleculemediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol 2009;5:100-7.
    • (2009) Nat Chem Biol , vol.5 , pp. 100-107
    • Chen, B.1    Dodge, M.E.2    Tang, W.3    Lu, J.4    Ma, Z.5    Fan, C.W.6
  • 30
    • 84881086323 scopus 로고    scopus 로고
    • Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
    • Timp W, Feinberg AP. Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer 2013; 13:497-510.
    • (2013) Nat Rev Cancer , vol.13 , pp. 497-510
    • Timp, W.1    Feinberg, A.P.2
  • 31
    • 0027052350 scopus 로고
    • Expression of bone morphogenetic proteins in human prostatic adenocarcinomaand benign prostatic hyperplasia
    • Bentley H, Hamdy FC, Hart KA, Seid JM, Williams JL, Johnstone D, et al. Expression of bone morphogenetic proteins in human prostatic adenocarcinomaand benign prostatic hyperplasia. Br J Cancer 1992;66:1159-63.
    • (1992) Br J Cancer , vol.66 , pp. 1159-1163
    • Bentley, H.1    Hamdy, F.C.2    Hart, K.A.3    Seid, J.M.4    Williams, J.L.5    Johnstone, D.6
  • 32
    • 34547580553 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their receptor signaling in prostate cancer
    • Ye L, Lewis-Russell JM, Kyanaston HG, Jiang WG. Bone morphogenetic proteins and their receptor signaling in prostate cancer. HistolHistopathol 2007;22:1129-47.
    • (2007) HistolHistopathol , vol.22 , pp. 1129-1147
    • Ye, L.1    Lewis-Russell, J.M.2    Kyanaston, H.G.3    Jiang, W.G.4
  • 34
    • 0037369118 scopus 로고    scopus 로고
    • Increased expression of bone morphogenetic protein-7 in bone metastatic prostate cancer
    • Masuda H, Fukabori Y, Nakano K, Takezawa Y, T CS, Yamanaka H. Increased expression of bone morphogenetic protein-7 in bone metastatic prostate cancer. Prostate 2003;54:268-74.
    • (2003) Prostate , vol.54 , pp. 268-274
    • Masuda, H.1    Fukabori, Y.2    Nakano, K.3    Takezawa, Y.4    Cs, T.5    Yamanaka, H.6
  • 35
    • 29844443964 scopus 로고    scopus 로고
    • Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies
    • Mimeault M, Batra SK. Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies. Carcinogenesis 2006;27:1-22.
    • (2006) Carcinogenesis , vol.27 , pp. 1-22
    • Mimeault, M.1    Batra, S.K.2
  • 36
    • 79952772716 scopus 로고    scopus 로고
    • Inhibition of tumor growth and sensitization to chemotherapy by RNA interference targeting interleukin-6 in the androgen-independent human prostate cancer PC3 model
    • Sakai I, Miyake H, Terakawa T, Fujisawa M. Inhibition of tumor growth and sensitization to chemotherapy by RNA interference targeting interleukin-6 in the androgen-independent human prostate cancer PC3 model. Cancer Sci 2011;102:769-75.
    • (2011) Cancer Sci , vol.102 , pp. 769-775
    • Sakai, I.1    Miyake, H.2    Terakawa, T.3    Fujisawa, M.4
  • 37
    • 79956126860 scopus 로고    scopus 로고
    • IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR
    • Rojas A, Liu G, Coleman I, Nelson PS, Zhang M, Dash R, et al. IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR. Oncogene 2011;30:2345-55.
    • (2011) Oncogene , vol.30 , pp. 2345-2355
    • Rojas, A.1    Liu, G.2    Coleman, I.3    Nelson, P.S.4    Zhang, M.5    Dash, R.6
  • 38
    • 77953091816 scopus 로고    scopus 로고
    • Clinical and correlative results of SWOG S0354: A phase II trial of CNTO328 (siltuximab), a monoclonal antibody against interleukin-6, in chemotherapy-pretreated patients with castration-resistant prostate cancer
    • Dorff TB, Goldman B, Pinski JK, Mack PC, Lara PN Jr, Van Veldhuizen PJ Jr, et al. Clinical and correlative results of SWOG S0354: a phase II trial of CNTO328 (siltuximab), a monoclonal antibody against interleukin-6, in chemotherapy-pretreated patients with castration-resistant prostate cancer. Clin Cancer Res 2010;16:3028-34.
    • (2010) Clin Cancer Res , vol.16 , pp. 3028-3034
    • Dorff, T.B.1    Goldman, B.2    Pinski, J.K.3    Mack, P.C.4    Lara, P.N.5    Van Veldhuizen, P.J.6
  • 40
    • 77954527232 scopus 로고    scopus 로고
    • Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists
    • Rider CC, Mulloy B. Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists. Biochem J 2010;429:1-12.
    • (2010) Biochem J , vol.429 , pp. 1-12
    • Rider, C.C.1    Mulloy, B.2
  • 41
    • 84876854791 scopus 로고    scopus 로고
    • Iron and cancer: More ore to be mined
    • Torti SV, Torti FM. Iron and cancer: more ore to be mined. Nat Rev Cancer 2013;13:342-55.
    • (2013) Nat Rev Cancer , vol.13 , pp. 342-355
    • Torti, S.V.1    Torti, F.M.2
  • 42
  • 43
    • 84874302553 scopus 로고    scopus 로고
    • Highthroughput screening of small molecules identifies hepcidin antagonists
    • Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E. Highthroughput screening of small molecules identifies hepcidin antagonists. Mol Pharmacol 2013;83:681-90.
    • (2013) Mol Pharmacol , vol.83 , pp. 681-690
    • Fung, E.1    Sugianto, P.2    Hsu, J.3    Damoiseaux, R.4    Ganz, T.5    Nemeth, E.6
  • 44
    • 67349204418 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD
    • Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU. Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD. J Mol Med 2009;87:471-80.
    • (2009) J Mol Med , vol.87 , pp. 471-480
    • Casanovas, G.1    Mleczko-Sanecka, K.2    Altamura, S.3    Hentze, M.W.4    Muckenthaler, M.U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.