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Volumn 75, Issue 13, 2015, Pages 2607-2618

Quantifying the landscape for development and cancer from a core cancer stem cell circuit

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER STEM CELL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL FATE; CELL RENEWAL; DEVELOPMENT; GENE ACTIVATION; GENE EXPRESSION; GENE INTERACTION; GENE REGULATORY NETWORK; GENE REPRESSION; HUMAN; MATHEMATICAL MODEL; NEOPLASM; PRIORITY JOURNAL; STEM CELL; TUMOR SUPPRESSOR GENE; BIOLOGICAL MODEL; CELL TRANSFORMATION; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; PHYSIOLOGY;

EID: 84942576109     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-0079     Document Type: Article
Times cited : (62)

References (50)
  • 1
    • 34248199004 scopus 로고    scopus 로고
    • Bifurcation dynamics of cell fate decision lineage-commitment in bipotent progenitor cells
    • Huang S, Guo Y, May G, Enver T. Bifurcation dynamics of cell fate decision lineage-commitment in bipotent progenitor cells. Dev Biol 2007;305:695-713.
    • (2007) Dev Biol , vol.305 , pp. 695-713
    • Huang, S.1    Guo, Y.2    May, G.3    Enver, T.4
  • 3
    • 0003392542 scopus 로고
    • Hao B, editor. Shanghai: Shanghai Scientific and Technological Education Press
    • Hu G. Stochastic forces and nonlinear systems. Hao B, editor. Shanghai: Shanghai Scientific and Technological Education Press; 1994.
    • (1994) Stochastic Forces and Nonlinear Systems
    • Hu, G.1
  • 4
    • 0015074045 scopus 로고
    • Differentiation of malignant to benign cells
    • Kauffman S. Differentiation of malignant to benign cells. J Theor Biol 1971;31:429-51.
    • (1971) J Theor Biol , vol.31 , pp. 429-451
    • Kauffman, S.1
  • 5
    • 70349330663 scopus 로고    scopus 로고
    • Cancer attractors: A systems view of tumors from agene network dynamics and developmental perspective
    • Huang S, Ernberg I, Kauffman S. Cancer attractors: a systems view of tumors from agene network dynamics and developmental perspective. Semin Cell Dev Biol 2009;20:869-76.
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 869-876
    • Huang, S.1    Ernberg, I.2    Kauffman, S.3
  • 6
    • 0141988694 scopus 로고    scopus 로고
    • An evolutionary model of carcinogenesis
    • Gatenby RA, Vincent TL. An evolutionary model of carcinogenesis. Cancer Res 2003;63:6212-20.
    • (2003) Cancer Res , vol.63 , pp. 6212-6220
    • Gatenby, R.A.1    Vincent, T.L.2
  • 7
    • 38749098685 scopus 로고    scopus 로고
    • Cancer as robust intrinsic state of endogenous molecular-cellular network shaped by evolution
    • L H
    • Ao P, Galas D, L H, Zhu X. Cancer as robust intrinsic state of endogenous molecular-cellular network shaped by evolution. Med Hypotheses 2008;70:678-84.
    • (2008) Med Hypotheses , vol.70 , pp. 678-684
    • Ao, P.1    Galas, D.2    Zhu, X.3
  • 8
    • 84887278742 scopus 로고    scopus 로고
    • MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination
    • Lu M, Jolly MK, Levine H, Onuchic JN, Ben-Jacob E. MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination. Proc Natl Acad Sci U S A 2013;110:18144-9.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 18144-18149
    • Lu, M.1    Jolly, M.K.2    Levine, H.3    Onuchic, J.N.4    Ben-Jacob, E.5
  • 9
    • 84908177103 scopus 로고    scopus 로고
    • Quantifying the underlying landscape and paths of cancer
    • Li C, Wang J. Quantifying the underlying landscape and paths of cancer. J R Soc Interface 2014;10:20140774.
    • (2014) J R Soc Interface , vol.10
    • Li, C.1    Wang, J.2
  • 10
    • 0036500609 scopus 로고    scopus 로고
    • A genomic regulatory network for development
    • Davidson EH. A genomic regulatory network for development. Science 2002;295:1669-78.
    • (2002) Science , vol.295 , pp. 1669-1678
    • Davidson, E.H.1
  • 12
    • 84942907146 scopus 로고
    • The strategy of the genes: A discussion of some aspects of theoretical biology
    • Waddington CH. The strategy of the genes: a discussion of some aspects of theoretical biology. London: Allen and Unwin; 1957.
    • (1957) London: Allen and Unwin;
    • Waddington, C.H.1
  • 13
    • 79957710315 scopus 로고    scopus 로고
    • Quantifying the waddington landscape and biological paths for development and differentiation
    • Wang J, Zhang K, Xu L, Wang EK. Quantifying the Waddington landscape and biological paths for development and differentiation. Proc Natl Acad Sci U S A 2011;108:8257-62.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 8257-8262
    • Wang, J.1    Zhang, K.2    Xu, L.3    Wang, E.K.4
  • 14
    • 84883349635 scopus 로고    scopus 로고
    • Quantifying cell fate decisions for differentiation and reprogramming of a human stem cell network: Landscape and biological paths
    • Li C, Wang J. Quantifying cell fate decisions for differentiation and reprogramming of a human stem cell network: landscape and biological paths. PLoS Comput Biol 2013;9:e1003165.
    • (2013) PLoS Comput Biol , vol.9
    • Li, C.1    Wang, J.2
  • 15
    • 77952914558 scopus 로고    scopus 로고
    • The potential landscape of genetic circuits imposes the arrow of time in stem cell differentiation
    • Wang J, Xu L, Wang EK, Huang S. The potential landscape of genetic circuits imposes the arrow of time in stem cell differentiation. Biophys J 2010; 99:29-39.
    • (2010) Biophys J , vol.99 , pp. 29-39
    • Wang, J.1    Xu, L.2    Wang, E.K.3    Huang, S.4
  • 16
    • 84928206114 scopus 로고    scopus 로고
    • Exploring the mechanisms of differentiation, dedifferentiation, reprogramming and transdifferentiation
    • Xu L, Zhang K, Wang J. Exploring the mechanisms of differentiation, dedifferentiation, reprogramming and transdifferentiation. PLoS ONE 2014;9:e105216.
    • (2014) PLoS ONE , vol.9
    • Xu, L.1    Zhang, K.2    Wang, J.3
  • 17
    • 60949084535 scopus 로고    scopus 로고
    • Cancer stem cells: A model in the making
    • Marotta LLC, Polyak K. Cancer stem cells: a model in the making. Curr Opin Genet Dev 2009;19:44-50.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 44-50
    • Marotta, L.L.C.1    Polyak, K.2
  • 19
    • 34047096557 scopus 로고    scopus 로고
    • Cancer stem cells: Models and concepts
    • Dalerba P, Cho RW, Clarke MF. Cancer stem cells: models and concepts. Annu Rev Med 2007;58:267-84.
    • (2007) Annu Rev Med , vol.58 , pp. 267-284
    • Dalerba, P.1    Cho, R.W.2    Clarke, M.F.3
  • 20
    • 84861194295 scopus 로고    scopus 로고
    • Cancer stem cells and metastasis
    • Sampieri K, Fodde R. Cancer stem cells and metastasis. Semin Cancer Biol 2012;22:187-93.
    • (2012) Semin Cancer Biol , vol.22 , pp. 187-193
    • Sampieri, K.1    Fodde, R.2
  • 23
    • 80051967505 scopus 로고    scopus 로고
    • Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
    • Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 2011;146:633-44.
    • (2011) Cell , vol.146 , pp. 633-644
    • Gupta, P.B.1    Fillmore, C.M.2    Jiang, G.3    Shapira, S.D.4    Tao, K.5    Kuperwasser, C.6
  • 24
    • 84865973282 scopus 로고    scopus 로고
    • An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state
    • Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci U S A 2012;109:14470-5.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 14470-14475
    • Polytarchou, C.1    Iliopoulos, D.2    Struhl, K.3
  • 25
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulatesOCT4, SOX2, and KLF4 and represses pluripotencyinhuman embryonic stem cells
    • Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulatesOCT4, SOX2, and KLF4 and represses pluripotencyinhuman embryonic stem cells. Cell 2009;137:647-58.
    • (2009) Cell , vol.137 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 26
    • 79951813950 scopus 로고    scopus 로고
    • The ZEB1/miR-200 feedback loop controls notch signalling in cancer cells
    • Brabletz S, Bajdak K, Meidhof S, Burk U, Niedermann G, Firat E, et al. The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J 2011;30:770-82.
    • (2011) EMBO J , vol.30 , pp. 770-782
    • Brabletz, S.1    Bajdak, K.2    Meidhof, S.3    Burk, U.4    Niedermann, G.5    Firat, E.6
  • 27
    • 79952283482 scopus 로고    scopus 로고
    • p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol 2011;13:317-23.
    • (2011) Nat Cell Biol , vol.13 , pp. 317-323
    • Chang, C.J.1    Chao, C.H.2    Xia, W.3    Yang, J.Y.4    Xiong, Y.5    Li, C.W.6
  • 28
    • 84871958603 scopus 로고    scopus 로고
    • Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop
    • Zhang J, Sun Q, Zhang Z, Ge S, Han Z, Chen W. Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene 2012;32:61-9.
    • (2012) Oncogene , vol.32 , pp. 61-69
    • Zhang, J.1    Sun, Q.2    Zhang, Z.3    Ge, S.4    Han, Z.5    Chen, W.6
  • 29
    • 84922345421 scopus 로고    scopus 로고
    • Towards elucidating the connection between epithelial-mesenchymal transitions and stemness
    • Jolly MK, Huang B, Lu M, Mani S, Levine H, Ben-Jacob E. Towards elucidating the connection between epithelial-mesenchymal transitions and stemness. J R Soc Interface 2014;11:20140962.
    • (2014) J R Soc Interface , vol.11
    • Jolly, M.K.1    Huang, B.2    Lu, M.3    Mani, S.4    Levine, H.5    Ben-Jacob, E.6
  • 30
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008;133:704-15.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 31
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008;9:582-9.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6
  • 32
    • 0037418265 scopus 로고    scopus 로고
    • Stochastic gene expression as a many-body problem
    • Sasai M, Wolynes P. Stochastic gene expression as a many-body problem. Proc Natl Acad Sci U S A 2003;100:2374-9.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2374-2379
    • Sasai, M.1    Wolynes, P.2
  • 33
    • 77952334362 scopus 로고    scopus 로고
    • Potential and flux landscapes quantify the stability and robustness of budding yeast cell cycle network
    • Wang J, Li C, Wang EK. Potential and flux landscapes quantify the stability and robustness of budding yeast cell cycle network. Proc Natl Acad Sci USA 2010;107:8195-200.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8195-8200
    • Wang, J.1    Li, C.2    Wang, E.K.3
  • 34
    • 84907587746 scopus 로고    scopus 로고
    • Landscape and flux reveal a new global view and physical quantification of mammalian cell cycle
    • Li C, Wang J. Landscape and flux reveal a new global view and physical quantification of mammalian cell cycle. Proc Natl Acad Sci U S A 2014; 111:14130-5.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 14130-14135
    • Li, C.1    Wang, J.2
  • 35
    • 84904316003 scopus 로고    scopus 로고
    • Stem cell differentiation as a many-body problem
    • Zhang B, Wolynes PG. Stem cell differentiation as a many-body problem. Proc Natl Acad Sci U S A 2014;111:10185-90.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 10185-10190
    • Zhang, B.1    Wolynes, P.G.2
  • 36
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008;22:894-907.
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 39
    • 69349100179 scopus 로고    scopus 로고
    • Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
    • Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, et al. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 2009;460:1132-5.
    • (2009) Nature , vol.460 , pp. 1132-1135
    • Hong, H.1    Takahashi, K.2    Ichisaka, T.3    Aoi, T.4    Kanagawa, O.5    Nakagawa, M.6
  • 40
    • 69349100455 scopus 로고    scopus 로고
    • Linking the p53 tumour suppressor pathway to somatic cell reprogramming
    • Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, Raya A, et al. Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 2009;460:1140-4.
    • (2009) Nature , vol.460 , pp. 1140-1144
    • Kawamura, T.1    Suzuki, J.2    Wang, Y.V.3    Menendez, S.4    Morera, L.B.5    Raya, A.6
  • 41
    • 46149089421 scopus 로고    scopus 로고
    • Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression
    • Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, et al. Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression. Cell 2008;134:62-73.
    • (2008) Cell , vol.134 , pp. 62-73
    • Godar, S.1    Ince, T.A.2    Bell, G.W.3    Feldser, D.4    Donaher, J.L.5    Bergh, J.6
  • 42
    • 84870063669 scopus 로고    scopus 로고
    • Acquired cancer stem cell phenotypes through oct4-mediated dedifferentiation
    • Kumar SM, Liu S, Lu H, Zhang H, Zhang PJ, Gimotty PA, et al. Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Oncogene 2012;31:4898-911.
    • (2012) Oncogene , vol.31 , pp. 4898-4911
    • Kumar, S.M.1    Liu, S.2    Lu, H.3    Zhang, H.4    Zhang, P.J.5    Gimotty, P.A.6
  • 43
    • 33847796969 scopus 로고    scopus 로고
    • From adult stem cells to cancer stem cells
    • Trosko JE. From adult stem cells to cancer stem cells. Ann N Y Acad Sci 2006;1089:36-58.
    • (2006) Ann N y Acad Sci , vol.1089 , pp. 36-58
    • Trosko, J.E.1
  • 45
    • 13944273471 scopus 로고    scopus 로고
    • p53 induces differentiation of mouse embryonic stem cells by suppressing nanog expression
    • Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, Appella E, et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 2004;7:165-71.
    • (2004) Nat Cell Biol , vol.7 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3    Mazur, S.J.4    Murphy, M.E.5    Appella, E.6
  • 46
    • 50449104011 scopus 로고    scopus 로고
    • Potential landscape and flux framework of non-equilibrium networks: Robustness, dissipation and coherence of biochemical oscillations
    • Wang J, Xu L, Wang EK. Potential landscape and flux framework of non-equilibrium networks: robustness, dissipation and coherence of biochemical oscillations. Proc Natl Acad Sci U S A 2008;105:12271-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 12271-12276
    • Wang, J.1    Xu, L.2    Wang, E.K.3
  • 47
    • 77957734642 scopus 로고    scopus 로고
    • Kinetic paths, time scale, and underlying landscapes: A path integral framework to study global natures of nonequilibrium systems and networks
    • Wang J, Zhang K, Wang EK. Kinetic paths, time scale, and underlying landscapes: A path integral framework to study global natures of nonequilibrium systems and networks. J Chem Phys 2010;133:125103:1-13.
    • (2010) J Chem Phys , vol.133 , pp. 1-13
    • Wang, J.1    Zhang, K.2    Wang, E.K.3
  • 49
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
    • Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010;29:4741-51.
    • (2010) Oncogene , vol.29 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 50
    • 84907059374 scopus 로고    scopus 로고
    • Toward decoding the principles of cancer metastasis circuits
    • Lu M, Jolly MK, Onuchic J, Ben-Jacob E. Toward decoding the principles of cancer metastasis circuits. Cancer Res 2014;74:4574-87.
    • (2014) Cancer Res , vol.74 , pp. 4574-4587
    • Lu, M.1    Jolly, M.K.2    Onuchic, J.3    Ben-Jacob, E.4


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