-
1
-
-
84942549319
-
Utility of the Auditory Brainstem Response evaluation in non-clinical drug safety evaluations
-
Abernathy M.M., Gauvin D.V., Tapp R.L., Yoder J.D., Baird T.J. Utility of the Auditory Brainstem Response evaluation in non-clinical drug safety evaluations. Journal of Pharmacological and Toxicological Methods 2015, 75:111-117.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 111-117
-
-
Abernathy, M.M.1
Gauvin, D.V.2
Tapp, R.L.3
Yoder, J.D.4
Baird, T.J.5
-
2
-
-
84942374527
-
Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes
-
Asakura K., Hayashi S., Ojima A., Taniguchi T., Miyamoto N., Nakamori C., et al. Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 2015, 75:17-26.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 17-26
-
-
Asakura, K.1
Hayashi, S.2
Ojima, A.3
Taniguchi, T.4
Miyamoto, N.5
Nakamori, C.6
-
3
-
-
84942366893
-
The Diplomate in Safety Pharmacology (DSP) certification scheme
-
Authier S., Curtis M.J., Soloviev M., Redfern W.S., Kallman M.J., Hamlin R.L., et al. The Diplomate in Safety Pharmacology (DSP) certification scheme. Journal of Pharmacological and Toxicological Methods 2015, 75:1-4.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 1-4
-
-
Authier, S.1
Curtis, M.J.2
Soloviev, M.3
Redfern, W.S.4
Kallman, M.J.5
Hamlin, R.L.6
-
4
-
-
84942553798
-
Renal studies in safety pharmacology and toxicology: A survey conducted in the top 15 pharmaceutical companies
-
Benjamin A., Gallacher D.J., Greiter-Wilke A., Guillon J.M., Kasai C., Ledieu D., et al. Renal studies in safety pharmacology and toxicology: A survey conducted in the top 15 pharmaceutical companies. Journal of Pharmacological and Toxicological Methods 2015, 75:101-110.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 101-110
-
-
Benjamin, A.1
Gallacher, D.J.2
Greiter-Wilke, A.3
Guillon, J.M.4
Kasai, C.5
Ledieu, D.6
-
5
-
-
0031214407
-
Effects of combined exposure to noise and toxic substances-Critical review of the literature
-
Cary R., Clarke S., Delic J. Effects of combined exposure to noise and toxic substances-Critical review of the literature. Annals of Occupational Hygiene 1997, 41:455-465.
-
(1997)
Annals of Occupational Hygiene
, vol.41
, pp. 455-465
-
-
Cary, R.1
Clarke, S.2
Delic, J.3
-
6
-
-
84942378090
-
Extended recording of rat locomotor activity in closed photobeam chambers: Effects on activity and arterial blood gases
-
(in press)
-
Gauvin D.V., Dalton J.A., Baird T.J. Extended recording of rat locomotor activity in closed photobeam chambers: Effects on activity and arterial blood gases. Journal of Pharmacological and Toxicological Methods 2015, (in press).
-
(2015)
Journal of Pharmacological and Toxicological Methods
-
-
Gauvin, D.V.1
Dalton, J.A.2
Baird, T.J.3
-
7
-
-
84942552230
-
Abuse liability assessment of hydrocodone under current draft regulatory guidelines
-
Gauvin D.V., McComb M., Code R., Dalton J.A., Baird T.J. Abuse liability assessment of hydrocodone under current draft regulatory guidelines. Journal of Pharmacological and Toxicological Methods 2015, 75:118-129.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 118-129
-
-
Gauvin, D.V.1
McComb, M.2
Code, R.3
Dalton, J.A.4
Baird, T.J.5
-
8
-
-
84928897709
-
Adult human stem cell-derived cardiomyocytes detect drug-mediated changes on action potentials
-
Gibson J.K., Yue Y., Bronson J., Palmer C., Numann R. Adult human stem cell-derived cardiomyocytes detect drug-mediated changes on action potentials. Journal of Pharmacological and Toxicological Methods 2014, 70:255-267.
-
(2014)
Journal of Pharmacological and Toxicological Methods
, vol.70
, pp. 255-267
-
-
Gibson, J.K.1
Yue, Y.2
Bronson, J.3
Palmer, C.4
Numann, R.5
-
9
-
-
84942550985
-
Improvements in self-administration studies based on changes in skin button type and surgical technique
-
Gilbert L.M., Sgro M.P., Modlin L.M., Wheat N.J., Kallman M.J. Improvements in self-administration studies based on changes in skin button type and surgical technique. Journal of Pharmacological and Toxicological Methods 2015, 75:130-134.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 130-134
-
-
Gilbert, L.M.1
Sgro, M.P.2
Modlin, L.M.3
Wheat, N.J.4
Kallman, M.J.5
-
11
-
-
84942549502
-
The evaluation of drug-induced changes in cardiac inotropy in dogs: Results from a HESI-sponsored consortium
-
Guth B.D., Chiang A.Y., Doyle J., Engwall M.J., Guillon J.M., Hoffmann P., et al. The evaluation of drug-induced changes in cardiac inotropy in dogs: Results from a HESI-sponsored consortium. Journal of Pharmacological and Toxicological Methods 2015, 75:70-90.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 70-90
-
-
Guth, B.D.1
Chiang, A.Y.2
Doyle, J.3
Engwall, M.J.4
Guillon, J.M.5
Hoffmann, P.6
-
12
-
-
84942549845
-
Telemetric assessment of social and single housing: Evaluation of electrocardiographic intervals in jacketed cynomolgus monkeys
-
Kaiser R.A., Tichenor S.D., Regalia D.E., York K., Holzgrefe H.H. Telemetric assessment of social and single housing: Evaluation of electrocardiographic intervals in jacketed cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 2015, 75:38-43.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 38-43
-
-
Kaiser, R.A.1
Tichenor, S.D.2
Regalia, D.E.3
York, K.4
Holzgrefe, H.H.5
-
13
-
-
33747882070
-
Optimizing the experimental environment for dog telemetry studies
-
Klumpp A., Trautmann T., Markert M., Guth B. Optimizing the experimental environment for dog telemetry studies. Journal of Pharmacological and Toxicological Methods 2006, 54:141-149.
-
(2006)
Journal of Pharmacological and Toxicological Methods
, vol.54
, pp. 141-149
-
-
Klumpp, A.1
Trautmann, T.2
Markert, M.3
Guth, B.4
-
14
-
-
84942552531
-
Evaluation of cardiovascular changes in dogs administered three positive controls using Jacketed External Telemetry-Blood Pressure (JET-BP)
-
Kremer J.J., Bills A.J., Hanke N., Chena H., Meiera W., Osinski M.A., et al. Evaluation of cardiovascular changes in dogs administered three positive controls using Jacketed External Telemetry-Blood Pressure (JET-BP). Journal of Pharmacological and Toxicological Methods 2015, 75:27-37.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 27-37
-
-
Kremer, J.J.1
Bills, A.J.2
Hanke, N.3
Chena, H.4
Meiera, W.5
Osinski, M.A.6
-
15
-
-
84942551022
-
Assessment of seizure risk in pre-clinical studies: Strengths and limitations of the electroencephalogram (EEG)
-
Metea M., Litwak M., Arrezzo J.A. Assessment of seizure risk in pre-clinical studies: Strengths and limitations of the electroencephalogram (EEG). Journal of Pharmacological and Toxicological Methods 2015, 75:135-142.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 135-142
-
-
Metea, M.1
Litwak, M.2
Arrezzo, J.A.3
-
16
-
-
84942549779
-
QT Interval correction assessment on the anesthetized guinea pig
-
Morrissette P., Regan H.K., Fitzgerald K., Bernasconi S., Gerenser P., Travis P., et al. QT Interval correction assessment on the anesthetized guinea pig. Journal of Pharmacological and Toxicological Methods 2015, 75:52-61.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 52-61
-
-
Morrissette, P.1
Regan, H.K.2
Fitzgerald, K.3
Bernasconi, S.4
Gerenser, P.5
Travis, P.6
-
18
-
-
79958158591
-
Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation
-
O'Hara T., Virág L., Varró A., Rudy Y. Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation. PLoS Computational Biology 2011, 7(5):e1002061. 10.1371/journal.pcbi.1002061.
-
(2011)
PLoS Computational Biology
, vol.7
, Issue.5
, pp. e1002061
-
-
O'Hara, T.1
Virág, L.2
Varró, A.3
Rudy, Y.4
-
19
-
-
84896689737
-
Computational models of ventricular and atrial-like human induced pluripotent stem cell derived cardiomyocytes
-
Paci M., Hyttinen J., Aalto-Setala K., Severi S. Computational models of ventricular and atrial-like human induced pluripotent stem cell derived cardiomyocytes. Annals of Biomedical Engineering 2013, 41:2334-2348.
-
(2013)
Annals of Biomedical Engineering
, vol.41
, pp. 2334-2348
-
-
Paci, M.1
Hyttinen, J.2
Aalto-Setala, K.3
Severi, S.4
-
20
-
-
77952292876
-
The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes
-
Peng S., Lacerda A.E., Kirsch G.E., Brown A.M., Bruening-Wright A. The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes. Journal of Pharmacological and Toxicological Methods 2010, 61:277-286.
-
(2010)
Journal of Pharmacological and Toxicological Methods
, vol.61
, pp. 277-286
-
-
Peng, S.1
Lacerda, A.E.2
Kirsch, G.E.3
Brown, A.M.4
Bruening-Wright, A.5
-
21
-
-
84880043414
-
A public-private consortium advances cardiac safety evaluation: achievements of the HESI Cardiac Safety Technical Committee
-
Pierson J.B., Berridge B.R., Brooks M.B., Dreher K., Koerner J., Schultze A.E., et al. A public-private consortium advances cardiac safety evaluation: achievements of the HESI Cardiac Safety Technical Committee. Journal of Pharmacological and Toxicological Methods 2013, 68:7-12.
-
(2013)
Journal of Pharmacological and Toxicological Methods
, vol.68
, pp. 7-12
-
-
Pierson, J.B.1
Berridge, B.R.2
Brooks, M.B.3
Dreher, K.4
Koerner, J.5
Schultze, A.E.6
-
23
-
-
84907008720
-
Safety pharmacology in 2014: New focus on non-cardiac methods and models
-
Pugsley M.K., Dalton J.A., Authier S., Curtis M.J. Safety pharmacology in 2014: New focus on non-cardiac methods and models. Journal of Pharmacological and Toxicological Methods 2014, 70:170-174.
-
(2014)
Journal of Pharmacological and Toxicological Methods
, vol.70
, pp. 170-174
-
-
Pugsley, M.K.1
Dalton, J.A.2
Authier, S.3
Curtis, M.J.4
-
24
-
-
85027928558
-
An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes
-
Rast G., Weber J., Disch C., Schuck E., Ittrich C., Guth B.D. An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods 2015, 75:91-100.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 91-100
-
-
Rast, G.1
Weber, J.2
Disch, C.3
Schuck, E.4
Ittrich, C.5
Guth, B.D.6
-
25
-
-
84896692500
-
Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium
-
Sager P.T., Gintant G., Turner J.R., Pettit S., Stockbridge N. Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium. American Heart Journal 2014, 16:292-300.
-
(2014)
American Heart Journal
, vol.16
, pp. 292-300
-
-
Sager, P.T.1
Gintant, G.2
Turner, J.R.3
Pettit, S.4
Stockbridge, N.5
-
26
-
-
84865651871
-
Left ventricular pressure, contractility and dP/dt(max) in nonclinical drug safety assessment studies
-
Sarazan R.D., Kroehle J.P., Main B.W. Left ventricular pressure, contractility and dP/dt(max) in nonclinical drug safety assessment studies. Journal of Pharmacological and Toxicological Methods 2012, 66:71-78.
-
(2012)
Journal of Pharmacological and Toxicological Methods
, vol.66
, pp. 71-78
-
-
Sarazan, R.D.1
Kroehle, J.P.2
Main, B.W.3
-
27
-
-
67349123365
-
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
-
Tanaka T., Tohyama S., Murata M., Nomura F., Kaneko T., Chen H., et al. In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochemical and Biophysical Research Communications 2009, 385:497-502.
-
(2009)
Biochemical and Biophysical Research Communications
, vol.385
, pp. 497-502
-
-
Tanaka, T.1
Tohyama, S.2
Murata, M.3
Nomura, F.4
Kaneko, T.5
Chen, H.6
-
29
-
-
84907080941
-
Schedules of controlled substances: Rescheduling of hydrocodone combination products from Schedule III to Schedule II
-
US DEA Schedules of controlled substances: Rescheduling of hydrocodone combination products from Schedule III to Schedule II. Federal Register 2014, 79:49661-49682.
-
(2014)
Federal Register
, vol.79
, pp. 49661-49682
-
-
-
30
-
-
84942378091
-
-
US Department of Justice
-
US DEA Drugs of abuse (2011 edition). A DEA resource guide 2014, US Department of Justice, (http://www.dea.gov/pr/multimedia-library/publications/drug_of_abuse.pdf).
-
(2014)
Drugs of abuse (2011 edition). A DEA resource guide
-
-
-
32
-
-
0035854839
-
ICHS7A: Safety pharmacology studies for human pharmaceuticals
-
US FDA ICHS7A: Safety pharmacology studies for human pharmaceuticals. Federal Register 2001, 66:36791-36792.
-
(2001)
Federal Register
, vol.66
, pp. 36791-36792
-
-
-
34
-
-
84942551329
-
Predictivity of in vitro non-clinical cardiac contractility assays for effects in humans - A literature search
-
Wallis R., Gharanei M., Maddock H.L. Predictivity of in vitro non-clinical cardiac contractility assays for effects in humans - A literature search. Journal of Pharmacological and Toxicological Methods 2015, 75:62-69.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 62-69
-
-
Wallis, R.1
Gharanei, M.2
Maddock, H.L.3
-
36
-
-
84942553775
-
Effects of group housing on ECG assessment in conscious cynomolgus monkeys
-
Xing G., Lu J., Hu M., Wang S., Zhao L., Zheng W., Schofield J., Oldman K., Adkins D., Yu H., Platz S., Ren J., Skinner M. Effects of group housing on ECG assessment in conscious cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 2015, 75:44-51.
-
(2015)
Journal of Pharmacological and Toxicological Methods
, vol.75
, pp. 44-51
-
-
Xing, G.1
Lu, J.2
Hu, M.3
Wang, S.4
Zhao, L.5
Zheng, W.6
Schofield, J.7
Oldman, K.8
Adkins, D.9
Yu, H.10
Platz, S.11
Ren, J.12
Skinner, M.13
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