An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes

Journal of Pharmacological and Toxicological Methods

Volumn 75, Issue , 2015, Pages 91-100

  Rast, Georg ^a   Weber, Jürgen ^a   Disch, Christoph ^b   Schuck, Elmar ^a   Ittrich, Carina ^a   Guth, Brian D ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b Konitel GmbH   (Germany)

Author keywords

Calcium transient; Cardiomyocyte; Field potential; Fura 2; Human induced pluripotent stem cell (hiPSC); Methods; Multi electrode array; Ratiometry

Indexed keywords

4 (2 BENZYLBENZOYL) 2,5 DIMETHYL 1H PYRROLE 3 CARBOXYLIC ACID METHYL ESTER; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; FLUORESCENT DYE; FURA 2; NIFEDIPINE; PYRROLE DERIVATIVE; RYANODINE;

CARDIAC MUSCLE CELL; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; HUMAN; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PROCEDURES; RADIOMETRY;

CALCIUM; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; FLUORESCENT DYES; FURA-2; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MYOCYTES, CARDIAC; NIFEDIPINE; PYRROLES; RADIOMETRY; RYANODINE;

EID: 85027928558     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2015.04.005     Document Type: Article

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