Utility of the auditory brainstem response evaluation in non-clinical drug safety evaluations

Journal of Pharmacological and Toxicological Methods

Volumn 75, Issue , 2015, Pages 111-117

  Abernathy, Matthew M ^a   Gauvin, David V ^a   Tapp, Rachel L ^a   Yoder, Joshua D ^a   Baird, Theodore J ^a  

^a MPI RESEARCH   (United States)

Author keywords

Auditory brainstem response evaluations; Auditory function; Drug safety; Drug induced hearing loss; Method; Ototoxicity; Risk assessment

Indexed keywords

AMINOGLYCOSIDE; CISPLATIN; KANAMYCIN; PLATINUM COMPLEX;

ARTICLE; AUDITORY STIMULATION; AUDITORY THRESHOLD; CONDUCTION DEAFNESS; DRUG SAFETY; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING; HEARING IMPAIRMENT; HUMAN; INNER EAR; MIDDLE EAR; MIXED HEARING LOSS; NONHUMAN; OTOTOXICITY; PERCEPTION DEAFNESS; RISK ASSESSMENT; SEDATION; TREATMENT RESPONSE; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; FOOD AND DRUG ADMINISTRATION; HEARING LOSS; PRECLINICAL STUDY; PROCEDURES; REPRODUCIBILITY; UNITED STATES;

ANIMALS; DRUG EVALUATION, PRECLINICAL; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; HEARING LOSS; HUMANS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 84942549319     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2015.05.005     Document Type: Article

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