Epigallocatechin 3-Gallate ameliorates bile duct ligation induced liver injury in mice by modulation of mitochondrial oxidative stress and inflammation

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Shen, Kezhen ^a,b   Feng, Xiaowen ^a,b   Su, Rong ^a,b   Xie, Haiyang ^a,b   Zhou, Lin ^a,b   Zheng, Shusen ^a,b,c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; EPIGALLOCATECHIN GALLATE; FIBRONECTIN; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MANGANESE SUPEROXIDE DISMUTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; CATECHIN; CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE DUCT LIGATION; CELL DEATH; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MECHANISM; GENE EXPRESSION; HEPATITIS; IN VITRO STUDY; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; MALE; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; SINGLE DRUG DOSE; ANALOGS AND DERIVATIVES; ANIMAL; CHOLESTASIS; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELL; INFLAMMATION; INJURIES; INTRAHEPATIC BILE DUCT; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY;

ANIMALS; BILE DUCTS, INTRAHEPATIC; CATECHIN; CELL DEATH; CHOLESTASIS; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; HEPATOCYTES; INFLAMMATION; LIVER CIRRHOSIS; MICE; MITOCHONDRIA; NF-KAPPA B; OXIDATIVE STRESS;

EID: 84942301344     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126278     Document Type: Article

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