High-fat diet decreases activity of the oxidative phosphorylation complexes and causes nonalcoholic steatohepatitis in mice

DMM Disease Models and Mechanisms

Volumn 7, Issue 11, 2014, Pages 1287-1296

  García Ruiz, Inmaculada ^a   Solís Muñoz, Pablo ^b   Fernández Moreira, Daniel ^c   Grau, Montserrat ^a   Colina, Francisco ^a   Muñoz Yagüe, Teresa ^a   Solís Herruzo, José A ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c Department of Bromatology and Food Hygiene Military Center of Veterinary of Defense   (Spain)

Author keywords

Mitochondrial respiratory chain; NADPH oxidase; Nitro oxidative stress; Nonalcoholic steatohepatitis; Oxidative phosphorylation; Proteomic

Indexed keywords

CASPASE 3; COLLAGEN TYPE 1; GAMMA INTERFERON; GENOMIC DNA; MELATONIN; MITOCHONDRIAL DNA; MONOCYTE CHEMOTACTIC PROTEIN 1; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; URIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; GENE EXPRESSION; LIPID DIET; MOUSE; NITROSATIVE STRESS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; ANIMAL; GENETIC TRANSCRIPTION; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE;

MUS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; DIET, HIGH-FAT; MICE; NADPH OXIDASE; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATIVE PHOSPHORYLATION; TRANSCRIPTION, GENETIC;

EID: 84919922568     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.016766     Document Type: Article

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