Epigallocatechin-3-gallate inhibits tax-dependent activation of nuclear factor Kappa B and of matrix metalloproteinase 9 in human T-cell lymphotropic virus-1 positive leukemia cells

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 3, 2014, Pages 1219-1225

  Harakeh, Steve ^a   Diab Assaf, Mona ^b   Azar, Rania ^b   Abdulla Hassan, Hani Mutlak ^a   Tayeb, Safwan ^a   Abou El Ardat, Khalil ^c   Damanhouri, Ghazi Abdullah ^a   Qadri, Ishtiaq ^a   Abuzenadah, Adel ^a   Chaudhary, Adeel ^a   Kumosani, Taha ^a   Niedzwiecki, Aleksandra ^d   Rath, Mathias ^d   Yacoub, Haitham ^a   Azhar, Esam ^a   Barbour, Elie ^c  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b Department of Anaesthesiology   (Saudi Arabia)

^c AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^d Dr Rath Research Institute   (Canada)

Author keywords

Acute T cell leukemia; Human T cell lymphotropic virus type I (HTLV 1); NF kB pathway; Tax

Indexed keywords

ANTIOXIDANT; CATECHIN; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MMP9 PROTEIN, HUMAN; NEUROPROTECTIVE AGENT; TAX PROTEIN; UROKINASE;

ARTICLE; BIOSYNTHESIS; CELL PROLIFERATION; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; HUMAN; HUMAN T CELL LEUKEMIA VIRUS 1; METABOLISM; PATHOGENICITY; T CELL LEUKEMIA; TRANSCRIPTION INITIATION; TUMOR CELL LINE; VIROLOGY;

ANTIOXIDANTS; CATECHIN; CELL LINE, TUMOR; CELL PROLIFERATION; GENE PRODUCTS, TAX; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MATRIX METALLOPROTEINASE 9; NEUROPROTECTIVE AGENTS; NF-KAPPA B; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84896820063     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.3.1219     Document Type: Article

References (48)

1. Afaq F, Adhami VM, Ahmad N, et al (2003). inhibition of ultraviolet b-mediated activation of nuclear factor κb in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate. Oncogene, 22, 1035-44.
2. Ahmad N, Gupta S, Mukhtar H (2000). green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor κb in cancer cells versus normal cells. Arch Biochem Biophys, 376, 338-46.
3. Azar R, Alard A, Susini C, et al (2009). 4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferation. EMBO J, 28, 3514-22.
4. Azar R, Najib S, Lahlou H, et al (2008). Phosphatidylinositol 3-kinase-dependent transcriptional silencing of the translational repressor 4E-BP1. Cell Mol Life Sci, 65, 3110-7.
5. Azar R, Susini C, Bousquet C, et al (2010). Control of contactinhibition by 4E-BP1 upregulation. Cell Cycle, 9, 1241-5.
6. Bazarbachi A, Plumelle Y, Carlos Ramos J, et al (2010). Metaanalysis on the use of zidovudine and interferon-alfa in adult T-cell leukemia/lymphoma showing improved survival in the leukemic subtypes. J Clin Oncol, 28, 4177-83.
7. El-Sabban ME, Nasr R, Dbaibo G, et al (2000). Arsenicinterferon-alpha-triggered apoptosis in HTLV-I transformed cells is associated with tax down-regulation and reversal of NF-kappa B activation. Blood, 96, 2849-55.
8. Feng X, Heyden NV, Ratner L (2003). Alpha interferon inhibits human T-cell leukemia virus type 1 assembly by preventing Gag interaction with rafts. J Virol, 77, 13389-95.
9. Graff JR, Boghaert ER, De Benedetti A, et al (1995). Reduction of translation initiation factor 4E decreases the malignancy of ras-transformed cloned rat embryo fibroblasts. Int J Cancer, 60, 255-63.
10. Harakeh S, Abu-El-Ardat K, Diab-Assaf M, et al (2008). Epigallocatechin-3-gallate induces apoptosis and cell cycle arrest in HTLV-1-positive and-negative leukemia cells. Med Oncol, 25, 30-9.
11. Harakeh S, Diab-Assaf M, Abu-El-Ardat K, et al (2006). Mechanistic aspects of apoptosis induction by l-lysine in both HTLV-1-positive and-negative cell lines. Chem Biol Interact, 164, 102-14.
12. Jeong SJ, Radonovich M, Brady JN, et al (2004). HTLV-I tax induces a novel interaction between p65/rela and p53 that results in inhibition of p53 transcriptional activity. Blood, 104, 1490-97.
13. Jiang Y, Muschel RJ (2002). Regulation of matrix metalloproteinase-9 (MMP-9) by translational efficiency in murine prostate carcinoma cells. Cancer Res, 62, 1910-4.
14. Kannian P, Green PL (2010). Human T lymphotropic virus type 1 (HTLV-1): molecular biology and oncogenesis. Viruses, 2, 2037-77.
15. Kchour G, Tarhini M, Kooshyar MM, et al (2009). Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL). Blood, 113, 6528-32.
16. Kim HS, Kim MH, Jeong M, et al (2004). EGCG blocks tumor promoter-induced MMP-9 expression via suppression of MAPK and AP-1 activation in human gastric AGS cells. Anticancer Res, 24, 747-53.
17. Lairmore MD, Haines R, Anupam R (2012). Mechanisms of human T-lymphotropic virus type 1 transmission and disease. Curr Opin Virol, 2, 474-81.
18. Li HC, Yashiki S, Sonoda J, et al (2000). Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients. Jpn J Cancer Res, 91, 34-40.
19. Marçais A, Suarez F, Sibon D, et al (2013). Therapeutic options for adult T-cell leukemia/lymphoma. Curr Oncol Rep, 15, 457-64.
20. Martineau Y, Azar R, Müller D, et al (2013). Pancreatic tumours escape from translational control through 4E-BP1 loss. Oncogene. Apr 8 [Epub ahead of print]
21. Mori N, Yamada Y, Ikeda S, et al (2002). Bay 11-7082 Inhibits transcription factor NF-kB and induces apoptosis of htlv-iinfected t-cell lines and primary adult t-cell leukemia cells. Blood, 100, 1828-34.
22. Nasr R, Hajj HE, Kfoury Y, et al (2011). Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON Target or OFF target effects? Viruses, 3, 750-69.
23. Nicot C, Mahieux R, Takemoto S, et al (2000). Bcl-X(L) is upregulated by HTLV-I and HTLV-II in vitro and in ex vivo ATLL samples. Blood, 96, 275-81.
24. Oeckinghaus A, Hayden MS, Ghosh S (2011). Crosstalk in NFkB signaling pathways. Nat Immunol, 12, 695-708.
25. Ohsugi T, Horie R, Kumasaka T, et al (2005). In vivo antitumor activity of the NF-kB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell Leukemia. Carcinogenesis, 26, 1382-8.
26. Okamoto K, Fujisawa J, Reth M, et al (2006). Human T-cell leukemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB. Genes Cells, 11, 177-91.
27. Otsuka T, Ogo T, Eto T, et al (1998). Growth inhibition of leukemic cells by (-)-epigallocatechingallate, the main constituent of green tea. Life Sci, 63, 1397-403.
28. Pyronnet S, Imataka H, Gingras AC, et al (1999). Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E. EMBO J, 18, 270-9.
29. Qin J, Wang Y, Bai Y, et al (2012). Epigallocatechin-3-gallate inhibits bladder cancer cell invasion via suppression of NFkB-mediated matrix metalloproteinase-9 expression. Mol Med Rep, 6, 1040-4.
30. Rauch DA, Ratner L (2011). Targeting HTLV-1 activation of NFκB in mouse models and ATLL patients. Viruses, 3, 886-900.
31. Sen T, Dutta A, Chatterjee A (2010). Epigallocatechin-3-gallate (EGCG) down regulates gelatinase-B (MMP-9) by involvement of FAK/ERK/NFkappaB and AP-1 in the human breast cancer cell line MDA-MB-231. Anticancer Drugs, 21, 632-44.
32. Singh BN, Shankar S and Srivastava RK (2011). Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications. Biochem Pharmacol, 82, 1807-21.
33. Singh M, Singh R, Bhui K, et al (2011). Tea polyphenols induce apoptosis through mitochondrial pathway and by inhibiting nuclear factor-kappaB and Akt activation in human cervical cancer cells. Oncol Res, 19, 245-57.
34. Suganuma M, Saha A and Fujiki H (2011). New cancer treatment strategy using combination of green tea catechins and anticancer drugs. Cancer Sci, 102, 317-23.
35. Syed DN, Afaq F, Kweon MH, et al (2007). Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NFkappaB activation in normal human bronchial epithelial cells. Oncogene, 26, 673-82.
36. Tabakin-Fix, I. Azran-Shaish, Y Schavinsky-Khrapunsky, et al (2006). HumanT-cell leukemia virus type 1: transition from latent infection to pathogenic progression and implications for molecular therapy. Curr Cancer Ther Rev, 2, 101-13.
37. Tanimura S, Kadomoto R, Tanaka T, et al (2005). Suppression of tumor cell invasiveness by hydrolyzable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity. Biochem Biophys Res Commun, 330, 1306-13.
38. Uota S, Zahidunnabi Dewan M, Saitoh Y, et al (2012). An IκB kinase 2 inhibitor IMD-0354 suppresses the survival of adult T-cell leukemia cells. Cancer Sci, 103, 100-6.
39. Van Aller GS, Carson JD, Tang W, et al (2011). Epigallocatechingallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor. Biochem Biophys Res Commun, 406, 194-9.
40. Vézina A, Chokor R, Annabi B (2012). EGCG targeting efficacy of NF-kB downstream gene products is dictated by the monocytic/macrophagic differentiation status of promyelocytic leukemia cells. Cancer Immunol Immunother, 61, 2321-31.
41. Wang J, Li J, Huang Y, et al (2013). Bcl-3 suppresses Taxinduced NF-kB activation through p65 nuclear translocation blockage in HTLV-1-infected cells. Int J Oncol, 42, 269-76.
42. Yan Z, Yong-Guang T, Fei-Jun L, et al (2004). Interference effect of epigallocatechin-3-gallate on targets of nuclear factor κB signal transduction pathways activated by EB virus encoded latent membrane protein 1. Int J Biochem Cell Biol, 36, 1473-81.
43. Yang J, Wei D, Liu J (2005). Repressions of MMP-9 expression and NF-kappa B localization are involved in inhibition of lung carcinoma 95-D cell invasion by (-)-epigallocatechin-3-gallate. Biomed Pharmacother, 59, 98-103.
44. Yao J, Liu Y, Wang X, et al (2009). UVB radiation induces human lens epithelial cell migration via NADPH oxidase-mediated generation of reactive oxygen species and up-regulation of matrix metalloproteinases. Int J Mol Med, 24, 153-9.
45. Yoshita M, Higuchi M, Takahashi M, et al (2012). The activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to IL-2-independent growth. Cancer Sci, 103, 369-74.
46. Zane L, Sibon D, Legras C, et al (2010). Clonal expansion of HTLV-1 positive CD8+ cells relies on cIAP-2 but not on c-FLIP expression. Virology, 407, 341-51.
47. Zhang J, Balestrieri E, Grelli S, et al (2001). Efficacy of 3'-azido 3'deoxythymidine (AZT) in preventing HTLV-1 transmission to human cord blood mononuclear cells. Virus Res, 78, 67-78.
48. Zhou F, Zhou H, Wang T, et al (2012). Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro. Acta Pharmacol Sin, 33, 120-6.