-
1
-
-
0042671357
-
Pre-mRNA splicing: Awash in a sea of proteins
-
Jurica,M.S. and Moore,M.J. (2003) Pre-mRNA splicing: awash in a sea of proteins. Mol. Cell, 12, 5-14.
-
(2003)
Mol. Cell
, vol.12
, pp. 5-14
-
-
Jurica, M.S.1
Moore, M.J.2
-
2
-
-
0344198459
-
The spliceosome: The most complex macromolecular machine in the cell?
-
Nilsen,T.W. (2003) The spliceosome: the most complex macromolecular machine in the cell? Bioessays, 25, 1147-1149.
-
(2003)
Bioessays
, vol.25
, pp. 1147-1149
-
-
Nilsen, T.W.1
-
3
-
-
0001877802
-
-
Gesteland,R and Atkins,J (eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor
-
Moore,M.J., Query,C.C. and Sharp,P.A. (1993) In: Gesteland,R and Atkins,J (eds). The RNA World. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp. 303-357.
-
(1993)
The RNA World
, pp. 303-357
-
-
Moore, M.J.1
Query, C.C.2
Sharp, P.A.3
-
5
-
-
0032489021
-
Mechanical devices of the spliceosome: Motors, clocks, springs, and things
-
Staley,J.P. and Guthrie,C. (1998) Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell, 92, 315-326.
-
(1998)
Cell
, vol.92
, pp. 315-326
-
-
Staley, J.P.1
Guthrie, C.2
-
6
-
-
0036948420
-
Allosteric cascade of spliceosome activation
-
Brow,D.A. (2002) Allosteric cascade of spliceosome activation. Annu. Rev. Genet., 36, 333-360.
-
(2002)
Annu. Rev. Genet.
, vol.36
, pp. 333-360
-
-
Brow, D.A.1
-
7
-
-
0032537739
-
RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
-
Raghunathan,P.L. and Guthrie,C. (1998) RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr. Biol., 8, 847-855.
-
(1998)
Curr. Biol.
, vol.8
, pp. 847-855
-
-
Raghunathan, P.L.1
Guthrie, C.2
-
8
-
-
0032515969
-
The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro
-
Laggerbauer,B., Achsel,T. and Luhrmann,R. (1998) The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro. Proc. Natl. Acad. Sci. U.S.A., 95, 4188-4192.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 4188-4192
-
-
Laggerbauer, B.1
Achsel, T.2
Luhrmann, R.3
-
9
-
-
0033056712
-
The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex
-
Kim,D.H. and Rossi,J.J. (1999) The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex. RNA, 5, 959-971.
-
(1999)
RNA
, vol.5
, pp. 959-971
-
-
Kim, D.H.1
Rossi, J.J.2
-
10
-
-
33746441457
-
The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase
-
Small,E.C., Leggett,S.R., Winans,A.A. and Staley,J.P. (2006) The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Mol. Cell, 23, 389-399.
-
(2006)
Mol. Cell
, vol.23
, pp. 389-399
-
-
Small, E.C.1
Leggett, S.R.2
Winans, A.A.3
Staley, J.P.4
-
11
-
-
71849087061
-
Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs
-
Zhao,C., Bellur,D.L., Lu,S., Zhao,F., Grassi,M.A., Bowne,S.J., Sullivan,L.S., Daiger,S.P., Chen,L.J., Pang,C.P. et al. (2009) Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs. Am. J. Hum. Genet., 85, 617-627.
-
(2009)
Am. J. Hum. Genet.
, vol.85
, pp. 617-627
-
-
Zhao, C.1
Bellur, D.L.2
Lu, S.3
Zhao, F.4
Grassi, M.A.5
Bowne, S.J.6
Sullivan, L.S.7
Daiger, S.P.8
Chen, L.J.9
Pang, C.P.10
-
12
-
-
79957582993
-
Next generation sequencing of pooled samples reveals new SNRNP200 mutations associated with retinitis pigmentosa
-
Benaglio,P., McGee,T.L., Capelli,L.P., Harper,S., Berson,E.L. and Rivolta,C. (2011) Next generation sequencing of pooled samples reveals new SNRNP200 mutations associated with retinitis pigmentosa. Hum. Mutat., 32, E2246-E2258.
-
(2011)
Hum. Mutat.
, vol.32
, pp. E2246-E2258
-
-
Benaglio, P.1
McGee, T.L.2
Capelli, L.P.3
Harper, S.4
Berson, E.L.5
Rivolta, C.6
-
13
-
-
84866529609
-
A novel missense SNRNP200 mutation associated with autosomal dominant retinitis pigmentosa in a Chinese family
-
Liu,T., Jin,X., Zhang,X., Yuan,H., Cheng,J., Lee,J., Zhang,B., Zhang,M., Wu,J., Wang,L. et al. (2012) A novel missense SNRNP200 mutation associated with autosomal dominant retinitis pigmentosa in a Chinese family. PLoS One, 7, e45464.
-
(2012)
PLoS One
, vol.7
-
-
Liu, T.1
Jin, X.2
Zhang, X.3
Yuan, H.4
Cheng, J.5
Lee, J.6
Zhang, B.7
Zhang, M.8
Wu, J.9
Wang, L.10
-
14
-
-
84893968426
-
Retinitis pigmentosa mutations of SNRNP200 enhance cryptic splice-site recognition
-
Cvackova,Z., Mateju,D. and Stanek,D. (2014) Retinitis pigmentosa mutations of SNRNP200 enhance cryptic splice-site recognition. Hum. Mutat., 35, 308-317.
-
(2014)
Hum. Mutat.
, vol.35
, pp. 308-317
-
-
Cvackova, Z.1
Mateju, D.2
Stanek, D.3
-
15
-
-
0029782402
-
The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases
-
Lauber,J., Fabrizio,P., Teigelkamp,S., Lane,W.S., Hartmann,E. and Luhrmann,R. (1996) The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases. EMBO J., 15, 4001-4015.
-
(1996)
EMBO J.
, vol.15
, pp. 4001-4015
-
-
Lauber, J.1
Fabrizio, P.2
Teigelkamp, S.3
Lane, W.S.4
Hartmann, E.5
Luhrmann, R.6
-
16
-
-
17844395704
-
Prp8 protein: At the heart of the spliceosome
-
Grainger,R.J. and Beggs,J.D. (2005) Prp8 protein: at the heart of the spliceosome. RNA, 11, 533-557.
-
(2005)
RNA
, vol.11
, pp. 533-557
-
-
Grainger, R.J.1
Beggs, J.D.2
-
17
-
-
23344449230
-
Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation
-
Brenner,T.J. and Guthrie,C. (2005) Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation. Genetics, 170, 1063-1080.
-
(2005)
Genetics
, vol.170
, pp. 1063-1080
-
-
Brenner, T.J.1
Guthrie, C.2
-
18
-
-
0036747295
-
The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome
-
Bartels,C., Klatt,C., Luhrmann,R. and Fabrizio,P. (2002) The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome. EMBO Rep., 3, 875-880.
-
(2002)
EMBO Rep.
, vol.3
, pp. 875-880
-
-
Bartels, C.1
Klatt, C.2
Luhrmann, R.3
Fabrizio, P.4
-
19
-
-
67650296697
-
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
-
Zhang,L., Xu,T., Maeder,C., Bud,L.O., Shanks,J., Nix,J., Guthrie,C., Pleiss,J.A. and Zhao,R. (2009) Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat. Struct. Mol. Biol., 16, 731-739.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 731-739
-
-
Zhang, L.1
Xu, T.2
Maeder, C.3
Bud, L.O.4
Shanks, J.5
Nix, J.6
Guthrie, C.7
Pleiss, J.A.8
Zhao, R.9
-
20
-
-
69149090973
-
Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase
-
Pena,V., Jovin,S.M., Fabrizio,P., Orlowski,J., Bujnicki,J.M., Luhrmann,R. and Wahl,M.C. (2009) Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Mol. Cell, 35, 454-466.
-
(2009)
Mol. Cell
, vol.35
, pp. 454-466
-
-
Pena, V.1
Jovin, S.M.2
Fabrizio, P.3
Orlowski, J.4
Bujnicki, J.M.5
Luhrmann, R.6
Wahl, M.C.7
-
21
-
-
84867913431
-
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome
-
Santos,K.F., Jovin,S.M., Weber,G., Pena,V., Luhrmann,R. and Wahl,M.C. (2012) Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc. Natl. Acad. Sci. U.S.A., 109, 17418-17423.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 17418-17423
-
-
Santos, K.F.1
Jovin, S.M.2
Weber, G.3
Pena, V.4
Luhrmann, R.5
Wahl, M.C.6
-
22
-
-
0033010430
-
An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p
-
Staley,J.P. and Guthrie,C. (1999) An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p. Mol. Cell, 3, 55-64.
-
(1999)
Mol. Cell
, vol.3
, pp. 55-64
-
-
Staley, J.P.1
Guthrie, C.2
-
23
-
-
58949085244
-
An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol
-
Liu,H. and Naismith,J.H. (2008) An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol. BMC Biotechnol., 8, 91-100.
-
(2008)
BMC Biotechnol.
, vol.8
, pp. 91-100
-
-
Liu, H.1
Naismith, J.H.2
-
24
-
-
0003529272
-
-
Cold Spring Harbor Laboratory Press, Long Island, NY
-
Rose,M.D., Winston,F. and Heiter,P. (1990) Methods in Yeast Gentics: A Laboratory Course Manual. Cold Spring Harbor Laboratory Press, Long Island, NY.
-
(1990)
Methods in Yeast Gentics: A Laboratory Course Manual
-
-
Rose, M.D.1
Winston, F.2
Heiter, P.3
-
25
-
-
34247255773
-
Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components
-
Pleiss,J.A., Whitworth,G.B., Bergkessel,M. and Guthrie,C. (2007) Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components. PLoS Biol., 5, e90.
-
(2007)
PLoS Biol.
, vol.5
, pp. e90
-
-
Pleiss, J.A.1
Whitworth, G.B.2
Bergkessel, M.3
Guthrie, C.4
-
26
-
-
0035161567
-
Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae
-
Stevens,S.W., Barta,I., Ge,H.Y., Moore,R.E., Young,M.K., Lee,T.D. and Abelson,J. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA, 7, 1543-1553.
-
(2001)
RNA
, vol.7
, pp. 1543-1553
-
-
Stevens, S.W.1
Barta, I.2
Ge, H.Y.3
Moore, R.E.4
Young, M.K.5
Lee, T.D.6
Abelson, J.7
-
27
-
-
0027454568
-
A rapid assay for quantitative detection of specific RNAs
-
Li,Z. and Brow,D.A. (1993) A rapid assay for quantitative detection of specific RNAs. Nucleic Acids Res., 21, 4645-4646.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 4645-4646
-
-
Li, Z.1
Brow, D.A.2
-
28
-
-
84876016933
-
Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly
-
Li,X., Zhang,W., Xu,T., Ramsey,J., Zhang,L., Hill,R., Hansen,K.C., Hesselberth,J.R. and Zhao,R. (2013) Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly. Nucleic Acids Res., 41, 3805-3818.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 3805-3818
-
-
Li, X.1
Zhang, W.2
Xu, T.3
Ramsey, J.4
Zhang, L.5
Hill, R.6
Hansen, K.C.7
Hesselberth, J.R.8
Zhao, R.9
-
29
-
-
70449625597
-
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome
-
Fabrizio,P., Dannenberg,J., Dube,P., Kastner,B., Stark,H., Urlaub,H. and Luhrmann,R. (2009) The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol. Cell, 36, 593-608.
-
(2009)
Mol. Cell
, vol.36
, pp. 593-608
-
-
Fabrizio, P.1
Dannenberg, J.2
Dube, P.3
Kastner, B.4
Stark, H.5
Urlaub, H.6
Luhrmann, R.7
-
30
-
-
29244464778
-
Tube-gel digestion: A novel proteomic approach for high throughput analysis of membrane proteins
-
Lu,X. and Zhu,H. (2005) Tube-gel digestion: a novel proteomic approach for high throughput analysis of membrane proteins. Mol. Cell. Proteomics, 4, 1948-1958.
-
(2005)
Mol. Cell. Proteomics
, vol.4
, pp. 1948-1958
-
-
Lu, X.1
Zhu, H.2
-
31
-
-
0037444512
-
Fast-response proteomics by accelerated in-gel digestion of proteins
-
Havlis,J., Thomas,H., Sebela,M. and Shevchenko,A. (2003) Fast-response proteomics by accelerated in-gel digestion of proteins. Anal. Chem., 75, 1300-1306.
-
(2003)
Anal. Chem.
, vol.75
, pp. 1300-1306
-
-
Havlis, J.1
Thomas, H.2
Sebela, M.3
Shevchenko, A.4
-
32
-
-
84907752981
-
GeLC-MS/MS analysis of complex protein mixtures
-
Dzieciatkowska,M., Hill,R. and Hansen,K.C. (2014) GeLC-MS/MS analysis of complex protein mixtures. Methods Mol. Biol., 1156, 53-66.
-
(2014)
Methods Mol. Biol.
, vol.1156
, pp. 53-66
-
-
Dzieciatkowska, M.1
Hill, R.2
Hansen, K.C.3
-
33
-
-
84901194640
-
Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness in humans
-
Julian,C.G., Subudhi,A.W., Hill,R.C., Wilson,M.J., Dimmen,A.C., Hansen,K.C. and Roach,R.C. (2014) Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness in humans. J. Appl. Physiol. (1985), 116, 937-944.
-
(2014)
J. Appl. Physiol. (1985)
, vol.116
, pp. 937-944
-
-
Julian, C.G.1
Subudhi, A.W.2
Hill, R.C.3
Wilson, M.J.4
Dimmen, A.C.5
Hansen, K.C.6
Roach, R.C.7
-
34
-
-
27944508215
-
CLIP: A method for identifying protein-RNA interaction sites in living cells
-
Ule,J., Jensen,K., Mele,A. and Darnell,R.B. (2005) CLIP: a method for identifying protein-RNA interaction sites in living cells. Methods, 37, 376-386.
-
(2005)
Methods
, vol.37
, pp. 376-386
-
-
Ule, J.1
Jensen, K.2
Mele, A.3
Darnell, R.B.4
-
35
-
-
0036158942
-
Composition and functional characterization of the yeast spliceosomal penta-snRNP
-
Stevens,S.W., Ryan,D.E., Ge,H.Y., Moore,R.E., Young,M.K., Lee,T.D. and Abelson,J. (2002) Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol. Cell, 9, 31-44.
-
(2002)
Mol. Cell
, vol.9
, pp. 31-44
-
-
Stevens, S.W.1
Ryan, D.E.2
Ge, H.Y.3
Moore, R.E.4
Young, M.K.5
Lee, T.D.6
Abelson, J.7
-
36
-
-
84868592766
-
Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning
-
Hahn,D., Kudla,G., Tollervey,D. and Beggs,J.D. (2012) Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning. Genes Dev., 26, 2408-2421.
-
(2012)
Genes Dev.
, vol.26
, pp. 2408-2421
-
-
Hahn, D.1
Kudla, G.2
Tollervey, D.3
Beggs, J.D.4
-
37
-
-
84878849387
-
Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site
-
Nguyen,T.H., Li,J., Galej,W.P., Oshikane,H., Newman,A.J. and Nagai,K. (2013) Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site. Structure, 21, 910-919.
-
(2013)
Structure
, vol.21
, pp. 910-919
-
-
Nguyen, T.H.1
Li, J.2
Galej, W.P.3
Oshikane, H.4
Newman, A.J.5
Nagai, K.6
-
38
-
-
84890659579
-
An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8
-
Price,A.M., Gornemann,J., Guthrie,C. and Brow,D.A. (2014) An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8. RNA, 20, 46-60.
-
(2014)
RNA
, vol.20
, pp. 46-60
-
-
Price, A.M.1
Gornemann, J.2
Guthrie, C.3
Brow, D.A.4
-
39
-
-
0033047503
-
Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome
-
Kuhn,A.N., Li,Z. and Brow,D.A. (1999) Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome. Mol. Cell, 3, 65-75.
-
(1999)
Mol. Cell
, vol.3
, pp. 65-75
-
-
Kuhn, A.N.1
Li, Z.2
Brow, D.A.3
-
40
-
-
36248983726
-
A dynamic bulge in the U6 RNA internal stem-loop functions in spliceosome assembly and activation
-
McManus,C.J., Schwartz,M.L., Butcher,S.E. and Brow,D.A. (2007) A dynamic bulge in the U6 RNA internal stem-loop functions in spliceosome assembly and activation. RNA, 13, 2252-2265.
-
(2007)
RNA
, vol.13
, pp. 2252-2265
-
-
McManus, C.J.1
Schwartz, M.L.2
Butcher, S.E.3
Brow, D.A.4
-
41
-
-
0035053295
-
Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae
-
van Nues,R.W. and Beggs,J.D. (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics, 157, 1451-1467.
-
(2001)
Genetics
, vol.157
, pp. 1451-1467
-
-
Van Nues, R.W.1
Beggs, J.D.2
|