Protective Effect of Unsaturated Fatty Acids on Palmitic Acid-Induced Toxicity in Skeletal Muscle Cells is not Mediated by PPARδ Activation

Lipids

Volumn 50, Issue 10, 2015, Pages 955-964

  Tumova, Jana ^a   Malisova, Lucia ^a   Andel, Michal ^a   Trnka, Jan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Mitochondrial respiration; Mitochondrial uncoupling; PPAR ; PPAR agonist; Saturated fatty acid; Skeletal muscle cells; Unsaturated fatty acids

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE I; CYTOPROTECTIVE AGENT; LINOLEIC ACID; LINOLENIC ACID; MESSENGER RNA; OLEIC ACID; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PYRUVATE DEHYDROGENASE KINASE 4; UNCOUPLING PROTEIN 3; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; 3 [(4 ANILINO 2 METHOXYPHENYL)SULFAMOYL] 2 THENOIC ACID METHYL ESTER; CELL RECEPTOR; EDIBLE OIL; PPARD PROTEIN, MOUSE; SULFONE; THIAZOLE DERIVATIVE; THIOPHENE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; FATTY ACID OXIDATION; GENE EXPRESSION; MITOCHONDRIAL RESPIRATION; MOUSE; MUSCLE CELL; MYOBLAST; MYOTUBE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CELL DEATH; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; SKELETAL MUSCLE;

ANIMALS; CELL DEATH; CELL LINE; CELL SURVIVAL; DIETARY FATS, UNSATURATED; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; MUSCLE CELLS; MUSCLE, SKELETAL; PALMITIC ACID; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SULFONES; THIAZOLES; THIOPHENES;

EID: 84942191631     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-015-4058-0     Document Type: Article

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