Fatty acid-induced mitochondrial uncoupling in adipocytes as a key protective factor against insulin resistance and beta cell dysfunction: A new concept in the pathogenesis of obesity-associated type 2 diabetes mellitus

Diabetologia

Volumn 50, Issue 10, 2007, Pages 2036-2041

  Maassen, J A ^a,b   Romijn, J A ^a   Heine, R J ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Adipocytes; Fatty acids; HAART; Mitochondria; Thiazolidinedione; Type 2 diabetes mellitus

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; FATTY ACID;

ADIPOCYTE; CYTOSOL; DISEASE ASSOCIATION; FATTY ACID OXIDATION; HUMAN; INSULIN RESISTANCE; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

ADIPOCYTES; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ION CHANNELS; LIFE STYLE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; OBESITY;

EID: 34548504082     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0776-z     Document Type: Review

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