Palmitate-induced cell death and mitochondrial respiratory dysfunction in myoblasts are not prevented by mitochondria-targeted antioxidants

Cellular Physiology and Biochemistry

Volumn 33, Issue 5, 2014, Pages 1439-1451

  Patková, Jana ^a   Anděl, Michal ^a   Trnka, Jan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Mitochondria targeted antioxidants; Mitochondrial respiration; MitoQ; MitoTEMPOL; mtDNA integrity; Myoblasts; Myotubes; Palmitate; Skeletal muscle; Spare respiratory capacity

Indexed keywords

ANTIOXIDANT; CYTOPROTECTIVE AGENT; HYDROGEN PEROXIDE; MITOCHONDRIAL DNA; MITOQ; MITOTEMPOL; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; PALMITIC ACID DERIVATIVE; TEMPOL;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA DAMAGE; DRUG CYTOTOXICITY; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL RESPIRATION; MOUSE; MYOBLAST; MYOTUBE; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ANIMAL; CELL CULTURE; CELL DEATH; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PATHOLOGY; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL DIFFERENTIATION; CELL VIABILITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; OXYGEN CONSUMPTION; SKELETAL MUSCLE;

ANIMALS; ANTIOXIDANTS; CELL DEATH; CELLS, CULTURED; DNA DAMAGE; DNA, MITOCHONDRIAL; MICE; MITOCHONDRIA; MYOBLASTS; PALMITATES;

EID: 84900887397     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000358709     Document Type: Article

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