LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

Journal of Translational Medicine

Volumn 13, Issue 1, 2015, Pages

  Ti, Dongdong ^a   Hao, Haojie ^a   Tong, Chuan ^a   Liu, Jiejie ^a   Dong, Liang ^a   Zheng, Jingxi ^a   Zhao, Yali ^b   Liu, Huiling ^a   Fu, Xiaobing ^a   Han, Weidong ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b Hainan Branch of Chinese PLA General Hospital   (China)

Author keywords

Exosome; LPS preconditioning; Macrophage polarization; Mesenchymal stromal cells

Indexed keywords

CYTOKINE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MICRORNA; MICRORNA LET 7B; PROTEIN KINASE B; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; MIRNLET7 MICRORNA, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CENTRIFUGATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; EXOSOME; GENE EXPRESSION PROFILING; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOMODULATION; IMMUNOTHERAPY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MACROPHAGE POLARIZATION; MESENCHYMAL STROMA CELL; MICROARRAY ANALYSIS; NONHUMAN; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN INJURY; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SUPERNATANT; UPREGULATION; WESTERN BLOTTING; WOUND HEALING; CELL LINE; CYTOLOGY; DRUG EFFECTS; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; METABOLISM; PATHOLOGY; VALIDATION STUDY;

CELL LINE; EXOSOMES; HUMANS; IN VITRO TECHNIQUES; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MESENCHYMAL STROMAL CELLS; MICRORNAS;

EID: 84941931780     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-015-0642-6     Document Type: Article

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