The novel receptor C5aR2 is required for C5a-mediated human mast cell adhesion, migration, and proinflammatory mediator production

Journal of Immunology

Volumn 195, Issue 6, 2015, Pages 2774-2787

  Pundir, Priyanka ^a,d   MacDonald, Clayton A ^b   Kulka, Marianna ^b,c  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT COMPONENT C5A RECEPTOR 1; COMPLEMENT COMPONENT C5A RECEPTOR 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL INTERFERING RNA; STEM CELL FACTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ANDROSTANE DERIVATIVE; BETA ARRESTIN; C5AR1 PROTEIN, HUMAN; CCL2 PROTEIN, HUMAN; CHEMOKINE RECEPTOR; COMPLEMENT COMPONENT C5A; CXCL10 PROTEIN, HUMAN; GAMMA INTERFERON; GPR77 PROTEIN, HUMAN; IL4 PROTEIN, HUMAN; INTERLEUKIN 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE INHIBITOR; RETINA S ANTIGEN; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA; WORTMANNIN;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL SURFACE; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTERNALIZATION; MAST CELL DEGRANULATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CELL MOTION; DEGRANULATION; FIBROBLAST; GENETICS; IMMUNOLOGY; INFLAMMATION; MAST CELL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RNA INTERFERENCE;

ANDROSTADIENES; ANTIGENS, CD34; ARRESTINS; CELL ADHESION; CELL DEGRANULATION; CELL LINE; CELL MOVEMENT; CHEMOKINE CCL2; CHEMOKINE CXCL10; COMPLEMENT C5A; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-4; MAST CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, CHEMOKINE; RNA INTERFERENCE; RNA, SMALL INTERFERING; STEM CELL FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84941779673     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401348     Document Type: Article

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